|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Is the neutrophil to lymphocyte ratio associated with liver fibrosis in patients with chronic hepatitis B?显示文摘AIM: To determine the association between the neutrophil to lymphocyte(N/L) ratio and the degree of liver fibrosis in patients with chronic hepatitis B(CHB) infection. METHODS: Between December 2011 and February 2013, 129 consecutive CHB patients who were admitted to the study hospitals for histological evaluation of chronic hepatitis B-related liver fibrosis were included in this retrospective study. The patients were divided into two groups based on the fibrosis score: individuals with a fibrosis score of F0 or F1 were included in the 'no/minimal liver fibrosis' group, whereas patients with a fibrosis score of F2, F3, or F4 were included in the 'advanced liver fibrosis' group. The Statistical Package for Social Sciences 18.0 for Windows was used to analyze the data. A P value of < 0.05 was accepted as statistically significant.RESULTS: Three experienced and blinded pathologists evaluated the fibrotic status and inflammatory activity of 129 liver biopsy samples from the CHB patients. Following histopathological examination, the 'no/minimal fibrosis' group included 79 individuals, while the 'advanced fibrosis' group included 50 individuals. Mean(N/L) ratio levels were notably lower in patients with advanced fibrosis when compared with patients with no/minimal fibrosis. The mean value of the aspartate aminotransferase-platelet ratio index was markedly higher in cases with advanced fibrosis compared to those with no/minimal fibrosis.CONCLUSION: Reduced levels of the peripheral blood N/L ratio were found to give high sensitivity, specificity and predictive values in CHB patients with significant fibrosis. The prominent finding of our research suggests that the N/L ratio can be used as a novel noninvasive marker of fibrosis in patients with CHB. | Murat Kekilli Alpaslan Tanoglu Yusuf Serdar Sakin Mevlut Kurt Serkan Ocal Sait Bagci | 2015 | World Journal of Gastroenterology2015，21，18： | 15 |
| 2 | Protective effects of intravenous anesthetics on kidney tissue in obstructive jaundice显示文摘AIM:To evaluate the protective effects on kidney tissue of frequently used intravenous anesthetics(ketamine,propofol,thiopental,and fentanyl)in rats with obstructive jaundice.METHODS:There is an increased incidence of postoperative acute renal failure in patients with obstructive jaundice.Thirty-two Wistar-albino rats were randomly divided into four equal groups.Laparatomy was performed on each animal in the four groups and common bile ducts were ligated and severed on day 0.After 7 d,laparotomy was again performed using ketamine,propofol,thiopental,or fentanyl anesthesia whose antioxidative properties are well known in oxidative stress in a rat liver model of obstructive jaundice.After 2 h,the rats were sacrificed.Renal tissue specimens were analyzed for catalase,superoxide dismutase and malondialdehyde enzymes activities.All values are expressed as the mean±SD.P values less than 0.05 were considered statistically significant.RESULTS:All animals survived without complications until the end of the study.Enlargement in the bile duct and obstructive jaundice were observed in all rats.Catalase was found to be significantly lower in the fentanyl group than in the ketamine(P=0.039),propofol(P=0.012),and thiopental(P=0.001)groups.Superoxide dismutase activities were similar in all groups(P>0.05).Malondialdehyde was found to be significantly lower in the ketamine group than in the propofol(P=0.028),thiopental(P=0.002)and fentanyl(P=0.005)groups.Malondialdehyde was also lower in the fentanyl group than in the thiopental group(P=0.001).The results showed that obstructive jaundice sensitizes renal tissue to damage under the different anesthetics.CONCLUSION:Among the agents tested,ketamine and propofol generated the least amount of oxidative stres on renal tissues in this rat model of obstructive jaundice created by common bile duct ligation.The importance of free radical injury in renal tissue in obstructive jaundice under different intravenous anesthetics during hepatobiliary and liver transplant surgery should be considered for prevention of postoperative acute renal failure. | Sinan Hatipoglu Huseyin Yildiz Ertan Bulbuloglu Ismail Coskuner Ergul Belge Kurutas Filiz Hatipoglu Harun Ciralik Mehmet Sait Berhuni | 2014 | World Journal of Gastroenterology2014，20，12： | 9 |
| 3 | 以抗坏血酸作协同试剂时红土镍矿在硫酸溶液中的溶解(英文)显示文摘研究硫酸与抗坏血酸联用对恰尔达红土镍矿中镍和钴的溶解作用。作为比较,也研究柠檬酸、马来酸和硬脂酸等有机酸作为协同试剂的应用情况。结果表明,抗坏血酸和柠檬酸的使用显著改善了钴的溶解,而其他两种有机酸对浸出率的协同作用很小。对于镍的溶解,抗坏血酸是最有效的协同试剂,其次是柠檬酸、马来酸和硬脂酸。在本研究获得的最优条件下,即1 mol/L硫酸中加入4 g/L抗坏血酸、80°C、固液比1/10,浸出4 h后钴和镍的浸出率分别达到99%和98%以上。此外,浸出行为对抗坏血酸浓度的变化(2~4 g/L)较不敏感,这从操作角度来看是非常理想的。 | Sait KURSUNOGLU Zela Tanlega ICHLAS Muammer KAYA | 2018 | Transactions of Nonferrous Metals Society of China2018，28，8： | 3 |
| 4 | Mesenchymal stem cell therapy in patients with small bowel transplantation:Single center experience显示文摘AIM:To study the effects of mesenchymal stem cell(MSC) therapy on the prevention of acute rejection and graft vs host disease following small bowel transplantation.METHODS: In our transplantation center, 6 isolated intestinal transplants have been performed with MSC therapy since 2009. The primary reasons for transplants were short gut syndrome caused by surgical intestine resection for superior mesenteric artery thrombosis(n = 4), Crohn's disease(n = 1) and intestinal aganglionosis(n = 1). Two of the patients were children. At the time of reperfusion, the first dose of MSCs cultured from the patient's bone marrow was passedinto the transplanted intestinal artery at a dose of 1000000 cells/kg. The second and third doses of MSCs were given directly into the mesenteric artery through the arterial anastomosis using an angiography catheter on day 15 and 30 post-transplant.RESULTS: The median follow-up for these patients was 10.6 mo(min: 2 mo-max: 30 mo). Three of the patients developed severe acute rejection. One of these patients did not respond to bolus steroid therapy. Although the other two patients did respond to antirejection treatment, they developed severe fungal and bacterial infections. All of these patients died in the 2nd and 3rd months post-transplant due to sepsis. The remaining patients who did not have acute rejection had good quality of life with no complications observed during the follow-up period. In addition, their intestinal grafts were functioning properly in the 13th, 25th and 30th month post-transplant. The patients who survived did not encounter any problems related to MSC transplantation.CONCLUSION: Although this is a small case series and not a randomized study, it is our opinion that small bowel transplantation is an effective treatment for intestinal failure, and MSC therapy may help to prevent acute rejection and graft vs host disease following intestinal transplantation. | Sait Murat Do?an Sel?uk K?l?n? Eyüp Kebap?? Cem Tu?men Mustafa ?lmez Cezmi Karaca Alp Gürkan Ma?allah Baran Yusuf Kurtulmu? | 2014 | World Journal of Gastroenterology2014，20，25： | 3 |
| 5 | 采用硫酸浸出和添加酒石酸钾钠的氢氧化钠浸出从Yahyali非硫化浮选尾矿中回收锌和铅显示文摘采用硫酸浸出和添加酒石酸钾钠的氢氧化钠浸出从Yahyali非硫化浮选尾矿中回收锌和铅。在酸浸阶段,研究pH值、固液比和温度对尾矿中锌溶出的影响。在pH值为2、温度为40°C、固液比为20%、浸出时间为2 h的条件下,锌的溶出率达到82.3%,而铁和铅的溶出率低于0.5%。硫酸消耗量为110.6 kg/t(干尾矿)。浸出温度对尾矿中锌的溶出无有益的影响。酸浸液的电积试验结果表明,阴极产物含99.8%的Zn和0.15%的Fe。在碱浸阶段,添加酒石酸钾钠时铅的溶出率略有增加,浸出温度从40°C升高到80°C时,超过60%的Pb进入浸出液中。利用XRD和XRF分析最终的浸出渣。XRD分析结果表明,主要衍射峰来自针铁矿和石英,次要衍射峰属于菱锌矿和白铅矿。XRF分析结果显示,浸出渣含有70.3%的氧化铁。基于顺序浸出实验结果,浮选尾矿中的锌和铅可以被很好地浸出,而大量的铁留在浸出渣中。 | Sait KURSUNOGLU Soner TOP Muammer KAYA | 2020 | Transactions of Nonferrous Metals Society of China2020，30，12： | 3 |
| 6 | Digitally reinforced hematoxylin-eosin polarization technique in diagnosis of rectal amyloidosis显示文摘AIM:To investigate the efficacy of the digitally reinforced hematoxylin-eosin polarization(DRHEP)technique for detection of amyloidosis in rectal biopsies.METHODS:One hundred hematoxylin-eosin(HE)stained rectal biopsies with Congo-red(CR)-positive amyloid depositions and 50 control cases with CRnegative amyloid-mimicking areas were scanned blinded to the CR results for amyloid depositions under both bright and polarized light,and digitally photographed using the DRHEP technique,to accentuate the faint birefringence observed in HE slides under polarization.The results of DRHEP and HE evaluation were statistically correlated with CR polarization results with respect to presence and localization of amyloid deposits as well as amyloid types.RESULTS:Amyloid deposits showed yellowish-green birefringence by DRHEP,which allowed identification of amyloidosis in 41 HE-unsuspected cases(P=0.016),31 of which only had vascular deposits.True positivity was higher,and false negativity and positivity were lower by DRHEP,compared to evaluation by HE(69%,31%,and 0.8%vs 33%,67%,and 33%,respectively;P<0.0001).The sensitivity,specificity,accuracy,and positive and negative predictive values for DRHEP were69%,98%,78.6%,98.5%,and 61.25%,respectively.Reasons for DRHEP false negativity were presence of extensive background birefringence in 12 cases,absence of CR birefringent vessel in 3 cases,and missing of the tiny deposits in 9 cases,which could be improved by experience,especially in the latter case.No correlation was found between age,gender,sites of deposits,or amyloid types.CONCLUSION:The DRHEP technique improves diagnostic accuracy when used as an adjunct or a prior step to CR staining,especially for cases with limited tissues for further analysis. | Basak Doganavsargil Gulruh Emiroglu Buberal Huseyin Toz Banu Sarsik Burcin Pehlivanoglu Murat Sezak Sait Sen | 2015 | World Journal of Gastroenterology2015，21，6： | 2 |
| 7 | Protective effect of Spirulina platensis enriched in phenolic compounds against hepatotoxicity induced by CCl 4显示文摘 | Remziye Aysun Kepek?i Sait Polat Ahmet ?elik Nuray Bayat Saadet Demir?rs Saygideger | 2013 | Food Chemistry2013，，3： | 2 |
| 8 | Value of lead aVR in predicting acute occlusion of proximal left anterior descending coronary artery and in-hospital outcome in ST-elevation myocardial infarction: an electrocardiographic predictor of poor prognosis显示文摘 | Nazif Aygul Kurtulus Ozdemir Mehmet Tokac Meryem Ulku Aygul Mehmet Akif Duzenli Adnan Abaci Ahmet Bacaksiz Hüseyin Yazici Sait Bodur | 2008 | Journal of Electrocardiology2008，，4： | 2 |
| 9 | The effect of turbulence on NLOS underwater wireless optical communication channels [Invited]显示文摘Conventional line-of-sight underwater wireless optical communication(UWOC)links suffer from huge signal fading in the presence of oceanic turbulence due to misalignment,which is caused by variations in the refractive index in the water.Non-line-of-sight(NLOS)communication,a novel underwater communication configuration,which has eased the requirements on the alignment,is supposed to enhance the robustness of the UWOC links in the presence of such turbulence.This Letter experimentally and statistically studies the impact of turbulence that arises from temperature gradient variations and the presence of different air bubble populations on NLOS optical channels.The results suggest that temperature gradient-induced turbulence causes negligible signal fading to the NLOS link.Furthermore,the presence of air bubbles with different populations and sizes can enhance the received signal power by seizing the scattering phenomena from an ultraviolet 377 nm laser diode. | Mohammed Sait Xiaobin Sun Omar Alkhazragi Nasir Alfaraj Meiwei Kong Tien Khee Ng Boon S.Ooi | 2019 | Chinese Optics Letters2019，17，10： | 2 |
| 10 | Production of in vitro haploid plants from in situ induced haploid embryos in winter squash (Cucurbita maxima Duchesne ex Lam.) via irradiated pollen显示文摘 | Ertan Sait Kurtar Ahmet Balkaya | 2010 | Plant Cell Tissue and Organ Culture (PCTOC)2010，，3： | 2 |
| 11 | Dissolution behavior of Caldag lateritic nickel ore subjected to a sequential organic acid leaching method显示文摘The dissolution behavior of Caldag lateritic nickel ore subjected to a sequential organic acid leaching method was investigated. The effects of the type of organic acid, acid concentration, leaching time, and leaching temperature on the lateritic nickel ore were examined. Organic acids were used individually prior to sequential leaching. Citric acid was more effective than the other two acids for the selective leaching of nickel and cobalt. An increase in the citric acid concentration negligibly affected the dissolution of the metals, whereas temperature exhibited a strong beneficial effect. Oxalic acid was determined to be the most appropriate organic acid for the second leaching step. After 8 h(4 h + 4 h) of leaching with organic acids(0.5 M citric + 0.5 M oxalic) in sequence at 90°C, 89.63% Ni, 82.89% Co, and 69.63% Fe were leached from the lateritic nickel ore. A sequential citric + oxalic acid leaching method could represent a viable alternative for the dissolution of metals from lateritic nickel ore. | Sait Kursunoglu Muammer Kaya | 2015 | International Journal of Minerals,Metallurgy and Materials2015，22，11： | 2 |
| 12 | Association of Helicobacter pylori infection with systemic inflammation in preeclampsia显示文摘 | Yusuf üstün Yaprak Engin-üstün Esra ?zkaplan Bari? Otlu Mehmet Sait Tekereko?lu | 2010 | Journal of Maternal-Fetal and Neonatal Medicine2010，，4： | 2 |
| 13 | Red cell distribution width as a novel, simple, inexpensive predictor of mortality in patients with chronic heart failure显示文摘 | Sevket Balta Mehmet Aydogan Omer Kurt Murat Karaman Sait Demirkol Emin Ozgur Akgul | 2013 | International Journal of Cardiology2013，，： | 2 |
| 14 | Transcriptional profiling of granulosa cells from a patient with recurrent empty follicle syndrome显示文摘 | Mehmet Sait Inan Saad Al-Hassan Pinar Ozand Serdar Coskun | 2006 | Reproductive BioMedicine Online2006，，： | 2 |
| 15 | Efficacy of a Modified Sequential Therapy Including Bismuth Subcitrate as First‐Line Therapy to Eradicate H elicobacter pylori in a Turkish Population显示文摘 | Ahmet Uygun A. Melih OZEL Bulent Sivri Zulfikar Polat Halil Gen? Yusuf Serdar Sakin Gürkan ?elebi Oya Uygur‐Bayrami?li Cemal Nuri Er?in Abdurrahman Kadayif?i Ozdes Emer Armagan Gunal Sait Bagci | 2012 | Helicobacter2012，，6： | 2 |
| 16 | Enhanced accumu-lation of Pb in Indian mustard by soil-applied chelating ugents显示文摘 | Blaylock MJ Sait DE DushenkovS | 1997 | Environmental Science and Technology1997，31，： | 1 |
| 17 | The human sacrum and safe ap- proaches for screw placement显示文摘 | Candan A Sait N Amac K et aI | 2009 | Journal of Clinical Neuroscience2009，16，： | 1 |
| 18 | A simulated evolution approach to task matcging and scheduling in heterogeneous computing environments显示文摘 | Barada H Sait S M Baig N | 2002 | Engineering Applications of Artificial Intelligence2002，15，9： | 1 |
| 19 | High-resolution solid-state carbon-13 NMR study of chitosan and its salts with acids:conformational characterization of polymorphs and helical structures as viewed from the conformation-dependent carbon-13 chemical shifts显示文摘 | Saitō H Tabeta R Ogawa K | 1987 | Macromolecoles1987，20，： | 1 |
| 20 | Characterization of b-FGF mediated acceleration of axonal bronching in cultured rat hippocamplaneurons显示文摘 | Aoyagi A Nishikawa K Sait OH | 1994 | Brain Res1994，661，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员