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| 1 | Transcranial Doppler ultrasonography: From methodology to major clinical applications显示文摘Non-invasive Doppler ultrasonographic study of cerebral arteries [transcranial Doppler(TCD)] has been extensively applied on both outpatient and inpatient settings. It is performed placing a low-frequency(≤ 2 MHz) transducer on the scalp of the patient over specific acoustic windows, in order to visualize the intracranial arterial vessels and to evaluate the cerebral blood flow velocity and its alteration in many different conditions. Nowadays the most widespread indication for TCD in outpatient setting is the research of right to left shunting, responsable of so called 'paradoxical embolism', most often due to patency of foramen ovale which is responsable of the majority of cryptogenic strokes occuring in patients younger than 55 years old. TCD also allows to classify the grade of severity of such shunts using the so called 'microembolic signal grading score'. In addition TCD has found many useful applications in neurocritical care practice. It is useful on both adults and children for day-to-day bedside assessment of critical conditions including vasospasm in subarachnoidal haemorrhage(caused by aneurysm rupture or traumatic injury), traumatic brain injury, brain stem death. It is used also to evaluate cerebral hemodynamic changes after stroke. It also allows to investigate cerebral pressure autoregulation and for the clinical evaluation of cerebral autoregulatory reserve. | Antonello D'Andrea Marianna Conte Massimo Cavallaro Raffaella Scarafile Lucia Riegler Rosangela Cocchia Enrica Pezzullo Andreina Carbone Francesco Natale Giuseppe Santoro Pio Caso Maria Giovanna Russo Eduardo Bossone Raffaele Calabrò | 2016 | World Journal of Cardiology2016，8，7： | 10 |
| 2 | Heart and lung, a dangerous liaison-Tako-tsubo cardiomyopathy and respiratory diseases: A systematic review显示文摘AIM: To investigate the possible association between Tako-tsubo cardiomyopathy(TTC)-a reversible clini-cal condition mimicking an acute myocardial infarction characterized by multifactorial pathophysiologic mecha-nisms- and respiratory system diseases. METHODS: We systematically searched PubMed and EMBASE medical information sources, to identify the different triggering causes, limiting our search to ar-ticles in English. The search keywords were: 'tako-tsubo cardiomyopathy', 'takotsubo', 'takotsubo cardiomyopa-thy', 'broken heart syndrome', 'stress-induced cardio-myopathy', 'apical ballooning syndrome', and 'ampulla cardiomyopathy in combination with respiratory dis-eases, lung, pulmonary disease. For each kind of dis-ease, we registered: author, year and country of study, patient sex, age, concurring situation, and outcome. RESULTS: Out of a total of 1725 articles found, we se-lected 37 papers reporting a total of 38 patients. As ex-pected, most patients were women(81.6%), mean age was 65 ± 10 years. Outcome was favorable in 100% of cases, and all the patients have been discharged un-eventfully in a few days. CONCLUSION: An association between respiratory diseases and TTC is likely to exist. Patients with severe respiratory diseases, due to the high dosages of β2-agonists used or to the need of invasive procedures, are highly exposed to the risk of developing TTC. | Roberto Manfredini Fabio Fabbian Alfredo De Giorgi Marco Pala Alessandra Mallozzi Menegatti Claudia Parisi Elisa Misurati Ruana Tiseo Massimo Gallerani Raffaella Salmi Eduardo Bossone | 2014 | World Journal of Cardiology2014，6，5： | 3 |
| 3 | Cardiac damage in athlete's heart: When the “supernormal” heart fails!显示文摘Intense exercise may cause heart remodeling to compensate increases in blood pressure or volume by increasing muscle mass. Cardiac changes do not involve only the left ventricle, but all heart chambers. Physiological cardiac modeling in athletes is associated with normal or enhanced cardiac function, but recent studies have documented decrements in left ventricular function during intense exercise and the release of cardiac markers of necrosis in athlete's blood of uncertain significance. Furthermore, cardiac remodeling may predispose athletes to heart disease and result in electrical remodeling, responsible for arrhythmias. Athlete's heart is a physiological condition and does not require a specific treatment. In some conditions, it is important to differentiate the physiological adaptations from pathological conditions, such as hypertrophic cardiomyopathy, arrhythmogenic dysplasia of the right ventricle, and non-compaction myocardium, for the greater risk of sudden cardiac death of these conditions. Moreover, some drugs and performance-enhancing drugs can cause structural alterations and arrhythmias, therefore, their use should be excluded. | Andreina Carbone Antonello D’Andrea Lucia Riegler Raffaella Scarafile Enrica Pezzullo Francesca Martone Raffaella America Biagio Liccardo Maurizio Galderisi Eduardo Bossone Raffaele Calabrò | 2017 | World Journal of Cardiology2017，9，6： | 3 |
| 4 | Early and late complications associated with transcatheter occlusion of secundum atrial septal defect显示文摘 | Massimo Chessa Mario Carminati Gianfranco Butera Roberta Margherita Bini Manuela Drago Luca Rosti Alessandro Giamberti Giuseppe Pomè Eduardo Bossone Alessandro Frigiola | 2002 | Journal of the American College of Cardiology2002，，6： | 2 |
| 5 | Predicting Death in Patients With Acute Type A Aortic Dissection显示文摘 | Rajendra H. Mehta Toru Suzuki Peter G. Hagan Eduardo Bossone Dan Gilon Alfredo Llovet Luis C. Maroto Jeanna V. Cooper Dean E. Smith William F. Armstrong Christoph A. Nienaber Kim A. Eagle | 2002 | Circulation: Journal of the American Heart Association2002，，2： | 1 |
| 6 | Simple Risk Models to Predict Surgical Mortality in Acute Type A Aortic Dissection: The International Registry of Acute Aortic Dissection Score显示文摘 | Vincenzo Rampoldi Santi Trimarchi Kim A. Eagle Christoph A. Nienaber Jae K. Oh Eduardo Bossone Truls Myrmel Giuseppe M. Sangiorgi Carlo De Vincentiis Jeanna V. Cooper Jianming Fang Dean Smith Thomas Tsai Arun Raghupathy Rossella Fattori Udo Sechtem Michae | 2007 | The Annals of Thoracic Surgery2007，，1： | 1 |
| 7 | Role of Echocardiography in Takotsubo Cardiomyopathy显示文摘 | Rodolfo Citro Federico Piscione Guido Parodi Jorge Salerno-Uriarte Eduardo Bossone | 2013 | Heart Failure Clinics2013，，： | 1 |
| 8 | Reperfusion strategies for acute myocardial infarction in the elderly显示文摘 | Rajendra H. Mehta Christopher B. Granger Karen P. Alexander Eduardo Bossone Harvey D. White Michael H. Sketch | 2005 | Journal of the American College of Cardiology2005，，4： | 1 |
| 9 | Contemporary results of surgery in acute type A aortic dissection: The International Registry of Acute Aortic Dissection experience显示文摘 | Santi Trimarchi Christoph A. Nienaber Vincenzo Rampoldi Truls Myrmel Toru Suzuki Rajendra H. Mehta Eduardo Bossone Jeanna V. Cooper Dean E. Smith Lorenzo Menicanti Alessandro Frigiola Jae K. Oh Michael G. Deeb Eric M. Isselbacher Kim A. Eagle | 2004 | The Journal of Thoracic and Cardiovascular Surgery2004，，1： | 1 |
| 10 | Breaking Heart显示文摘 | Roberto Manfredini Raffaella Salmi Fabio Fabbian Fabio Manfredini Massimo Gallerani Eduardo Bossone | 2013 | Heart Failure Clinics2013，，： | 1 |
| 11 | Cardiac Toxicity after Anthracycline Chemotherapy in Childhood显示文摘 | Diana Iarussi Paolo Indolfi Maurizio Galderisi Eduardo Bossone | 2000 | Herz2000，，7： | 1 |
| 12 | Takotsubo Cardiomyopathy: Overview显示文摘 | Eduardo Bossone Gianluigi Savarese Francesco Ferrara Rodolfo Citro Susanna Mosca Francesca Musella Giuseppe Limongelli Roberto Manfredini Antonio Cittadini Pasquale Perrone Filardi | 2012 | Heart Failure Clinics2012，，： | 1 |
| 13 | Monday preference in onset of takotsubo cardiomyopathy显示文摘 | Roberto Manfredini Rodolfo Citro Mario Previtali Olga Vriz Quirino Ciampi Marco Pascotto Ercole Tagliamonte Gennaro Provenza Fabio Manfredini Eduardo Bossone | 2010 | American Journal of Emergency Medicine2010，，6： | 1 |
| 14 | Chronobiological Patterns of Onset of Tako-Tsubo Cardiomyopathy显示文摘 | Rodolfo Citro Mario Previtali Daniella Bovelli Olga Vriz Costantino Astarita Marco Mariano Patella Gennaro Provenza Corinna Armentano Quirino Ciampi Giovanni Gregorio Massimo Piepoli Eduardo Bossone Roberto Manfredini | 2009 | Journal of the American College of Cardiology2009，，2： | 1 |
| 15 | Comparison of aortic dissection in patients with and without Marfan’s syndrome (results from the International Registry of Aortic Dissection)显示文摘 | James L Januzzi Firas Marayati Rajendra H Mehta Jeanna V Cooper Patrick T O’Gara Udo Sechtem Eduardo Bossone Arturo Evangelista Jae K Oh Christoph A Nienaber Kim A Eagle Eric M Isselbacher | 2004 | The American Journal of Cardiology2004，，3： | 1 |
| 16 | Patient selection for transcatheter aortic valve replacement:A combined clinical and multimodality imaging approach显示文摘Transcatheter aortic valve replacement(TAVR) has been validated as a new therapy for patients affected by severe symptomatic aortic stenosis who are not eligible for surgical intervention because of major contraindication or high operative risk. Patient selection for TAVR should be based not only on accurate assessment of aortic stenosis morphology, but also on several clinical and functional data. Multi-Imaging modalities should be preferred for assessing the anatomy and the dimensions of the aortic valve and annulus before TAVR. Ultrasounds represent the first line tool in evaluation of this patients giving detailed anatomic description of aortic valve complex and allowing estimating with enough reliability the hemodynamic entity of valvular stenosis. Angiography should be used to assess coronary involvement and plan a revascularization strategy before the implant. Multislice computed tomography play a central role as it can give anatomical details in order to choice the best fitting prosthesis, evaluate the morphology of the access path and detect other relevant comorbidities. Cardiovascular magnetic resonance and positron emission tomography are emergent modality helpful in aortic stenosis evaluation. The aim of this review is to give an overview onTAVR clinical and technical aspects essential for adequate selection. | Rosangela Cocchia Antonello D’Andrea Marianna Conte Massimo Cavallaro Lucia Riegler Rodolfo Citro Cesare Sirignano Massimo Imbriaco Maurizio Cappelli Giovanni Gregorio Raffaele Calabrò Eduardo Bossone | 2017 | World Journal of Cardiology2017，9，3： | 1 |
| 17 | Predicting Death in Patients With Acute Type A Aortic Dissection显示文摘 | Rajendra H. Mehta Toru Suzuki Peter G. Hagan Eduardo Bossone Dan Gilon Alfredo Llovet Luis C. Maroto Jeanna V. Cooper Dean E. Smith William F. Armstrong Christoph A. Nienaber Kim A. Eagle | 2002 | Circulation: Journal of the American Heart Association2002，，2： | 1 |
| 18 | Standard and Advanced Echocardiography in Takotsubo (Stress) Cardiomyopathy: Clinical and Prognostic Implications显示文摘 | Rodolfo Citro Alexander R. Lyon Patrick Meimoun Elmir Omerovic Bj?rn Redfors Thomas Buck Stamatios Lerakis Guido Parodi Angelo Silverio Ingo Eitel Birke Schneider Abhiram Prasad Eduardo Bossone | 2015 | Journal of the American Society of Echocardiograp2015，，： | 1 |
| 19 | Acute type A aortic dissection in the elderly: clinical characteristics, management, and outcomes in the current era显示文摘 | Rajendra H. Mehta Patrick T. O’Gara Eduardo Bossone Christoph A. Nienaber Truls Myrmel Jeanna V. Cooper Dean E. Smith William F. Armstrong Eric M. Isselbacher Linda A. Pape Kim A. Eagle Dan Gilon | 2002 | Journal of the American College of Cardiology2002，，4： | 1 |
| 20 | Multimodality imaging in COVID-19 patients:A key role from diagnosis to prognosis显示文摘The integrated clinical,laboratory and ultrasound approach is essential for the diagnosis,evaluation and monitoring of the patient's therapy in coronavirus disease 2019 pneumonia.The ideal imaging approach in this context is not yet well defined.Chest X-ray is characterized by low sensitivity in identifying earlier lung changes.The'bedside'pulmonary ultrasound has an undeniable series of advantages in the patient at high infectious risk and can provide incremental data in the respiratory intensive care for the serial control of the individual patient as well as for the home delivery of the stabilized subjects.Pulmonary computed tomography shows high sensitivity but should not be routinely performed in all patients,because in the first 48 h it can be absolutely negative and in the late phase the imaging findings may not change the therapeutic approach.Echocardiography should be limited to patients with hemodynamic instability to assess ventricular function and pulmonary pressures. | Antonello D'Andrea Juri Radmilovic Andreina Carbone Alberto Forni Ercole Tagliamonte Lucia Riegler Biagio Liccardo Fabio Crescibene Cesare Sirignano Giovanna Esposito Eduardo Bossone | 2020 | World Journal of Radiology2020，12，11： | 0 |
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