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80篇 您的检索式:作者名="Citro"
    题名 作者 年代 出处 被引量
1Cysteinyl-leukotrienes in the regulation of β2-adrenoceptor function:an in vitro model of asthma显示文摘G Enrico Rovati Michele Baroffio Simona Citro 2006Respiratory Research2006,7,:1
2Cysteingleukot rienes in the regulation of β2-adrenoeeptor function: an in vitro model of ashma显示文摘Rovati GE MBaroffio M Citro S 2006Repiratory Research2006,,7:1
3PI3K/mTOR mediate mitogen-dependent HDAC1 phosphorylation in breast cancer:a novel regulation of estrogen receptor expression显示文摘Histone deacetylase 1(HDAC1)is an important epigenetic controller involvedin transcriptional regulation throughmodification of chromatin structure.Genetic and epigenetic changes and deregulation of signal transduction pathways have been implicated in the development of breast cancer.Downregulation of estrogen receptor a(ERa)expression is one of the mechanisms behind the acquisition of endocrine resistance.Sustained and increased hormone and growth factor receptor signaling in breast cancer cells contribute to resistance to endocrine therapy.Both HDACs and the PI3K/mTOR signaling pathway are becoming promising targets in breast cancer,reversing also acquired hormone resistance.Here we show how mitogens,activating the PI3K/mTOR pathway,trigger the phosphorylation of HDAC1 in breast cancer cells,which is completely dependent on the activity of the p70 S6 kinase(S6K1).Our findings show that S6K1,overexpressed in many breast cancers,controls HDAC1-dependent transcriptional regulation of ERa levels upon mitogenic stimuli,controlling HDAC1 recruitment to the ERa promoter.Furthermore,cell treatment with both mTOR and HDACs inhibitors shows an additive effect in inhibiting breast cancer proliferation.This confirms the novel cross-talk between the HDAC1 and PI3K pathways with clinical implications towards the treatment of this malignant disease.Simona Citro Claudia Miccolo Laura Meloni Susanna Chiocca 2015Journal of Molecular Cell Biology2015,7,2:1
4Zero-conductance resonances and spin filtering effects in ring conductors subject to Rashba coupling显示文摘Citro R Romeo F Marinaro M 2006Phys Rev B2006,74,11:1
5Combined operations of renewable energy systems and responsive demand in a smart grid显示文摘Cecati C Citro C S iano P 2011IEEE Transactions on SustainableEnergy2011,2,4:1
6Indentification of gains and losses of DNA sequences in primary bladder cancer by comparative genomic hybridization显示文摘Kallioniemi A Kanioniemi OP Citro G 1995Genes Chromosomes Cancer1995,12,3:1
7Albumin excretion rate increases during acute myocardial infarction and strongly predicts early mortality显示文摘Berton G Citro T Palmieri R 1997Circulation1997,96,:1
8Widening the applicability of reactive distillation technology by using concurrent design显示文摘Citro F Lee J W 2004Ind Eng Chem Res2004,43,:1
9Identification of two surface proteins involved in the oxidation of sulphur compounds in Thiobacillus ferrooxidans 显示文摘BUONFIGLIO V POLIDORO M FLORA L CITRO G VALENTI P ORSI N 1993FEMS Microbiology Reviews1993,11,13:1
10c myc antisense oligodeoxynucleotides enhance the efficacy of cisp latin in melanoma chemotherapy in vitro and in nude mice显示文摘Citro G D' Agnano I Leonetti C 1998Cancer Res1998,58,2:1
11Role of Echocardiography in Takotsubo Cardiomyopathy显示文摘Rodolfo Citro Federico Piscione Guido Parodi Jorge Salerno-Uriarte Eduardo Bossone 2013Heart Failure Clinics2013,,:1
12What non-alcoholic fatty liver disease has got to do with obstructive sleep apnoea syndrome and viceversa? 显示文摘Tarantino G Citro V Fenilli C 2014J Gastrointestin Liver Dis2014,23,3:1
13A fundamental metric for continuity of care:Modeling and performance evaluation显示文摘Citro R Ghosh S Churgin PG 0,,03:1
14Anti-Inflammatory Strategies to Enhance Islet Engraftment and Survival显示文摘Antonio Citro Elisa Cantarelli Lorenzo Piemonti 2013Current Diabetes Reports2013,,5:1
15Endocrine dis- ruptors in utero cause ovarian damages linked to endome- triosis 显示文摘Signorile PG Spugnini EP Citro G 2012Front Biosei ( Elite Ed)2012,4,:1
16Analysis of beta1 and beta2-adrenergic receptors polymorphism in patients with apical ballooning cardiomyopathy显示文摘Vriz Q Minisini R Citro Rv 2011Acta Cardiol2011,66,6:1
17Inhibition of leukemia cell proliferation by receptor-mediated uptake of c-myb antisense oligonucleotides显示文摘Citro G Perrotti D Cucco C 1992Proc Natl Acad Sci US41992,89,15:1
18Cysteinyl-leukotrienes in the regulation of beta2-adrenoceptor function:an in vitro model of asthma显示文摘Rovati GE Baroffio M Citro S 2006Respir Res2006,7,1:1
19Randomized trial of dose-dense versus conventionally schedule and sequential versus concurrent combination chemotherapy as postoperative adjuvant treatment of node-positive primary breast cancer:first report of intergroup trial C9741/Cancer and leukemia group B trial 9741显示文摘Citro ML Berry DA Cirricione C 2003J Clin Oncol2003,27,7:1
20Immunochemical determination of lonidamine in rat tissues and blood serum显示文摘Citro Gennaro Galati Rossella Verdina Ale 1989Anticancer Res1989,9,3:1
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