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| 1 | Depression in patients with irritable bowel syndrome in Jos,Nigeria显示文摘AIM: To study the brain-gut interaction and the effect of behavioral or psychiatric conditions on irritable bowel syndrome (IBS) in an African population. METHODS: IBS was diagnosed using the Rome Ⅱ diagnostic criteria. The entry of each patient was confirmed following detailed explanations of the questions. Four hundred and eighteen patients were studied. Subjects satisfying the Rome Ⅱ criteria for IBS were physically examined and stool microscopy was done to identify the presence of “alarm factors”. Depression was diagnosed using the symptom-check list adapted from the Research Diagnostic Criteria (DSM-Ⅳ) of the American Psychiatric Association. RESULTS: Seventy-five (56.8%) of the 132 IBS patients were depressed whereas only 54 (20.1%) of the 268 non-IBS patients were depressed. There was a significant relationship between IBS and depression (χ2 = 54.29, Odds ratio = 5.21, 56.8 ± 8.4 vs 20.1 ± 5.2, P = 0.001). Even though constipation predominant IBS patients were more likely to be depressed, no significant relationship was found between the subtype of IBS and depression (χ2 = 0.02, OR = 0.95, P = 0.68). CONCLUSION: IBS is significantly associated with major depression but not gender and bowel subtypes of the patients. Patients with IBS need to be evaluated for depression due to the highly significant relationship between the two conditions. | Nimzing G Ladep Taiwo J Obindo Moses D Audu Edith N Okeke Abraham O Malu | 2006 | World Journal of Gastroenterology2006,12,48: | 22 |
| 2 | Possible contribution of artificial neural networks and linear discriminant analysis in recognition of patients with suspected atrophic body gastritis显示文摘AIM: To investigate whether ANNs and LDA could recognize patients with ABG in a database, containing only clinical and biochemical variables, of a pool of patients with and without ABG, by selecting the most predictive variables and by reducing input data to the minimum.METHODS: Data was collected from 350 consecutive outpatients (263 with ABG, 87 with non-atrophic gastritis and/or celiac disease [controls]). Structured questionnaires with 22 items (anagraphic, anamnestic, clinical, and biochemical data) were filled out for each patient. All patients underwent gastroscopy with biopsies. ANNs and LDA were applied to recognize patients with ABG.Experiment 1: random selection on 37 variables, experiment 2: optimization process on 30 variables, experiment 3:input data reduction on 8 variables, experiment 4: use of only clinical input data on 5 variables, and experiment 5:use of only serological variables.RESULTS: In experiment 1, overall accuracies of ANNs and LDA were 96.6% and 94.6%, respectively, for predicting patients with ABG. In experiment 2, ANNs and LDA reached an overall accuracy of 98.8% and 96.8%,respectively. In experiment 3, overall accuracy of ANNs was 98.4%. In experiment 4, overall accuracies of ANNs and LDA were, respectively, 91.3% and 88.6%. In experiment 5, overall accuracies of ANNs and LDA were,respectively, 97.7% and 94.5%.CONCLUSION: This preliminary study suggests that advanced statistical methods, not only ANNs, but also LDA,may contribute to better address bioptic sampling during gastroscopy in a subset of patients in whom ABG may be suspected on the basis of aspecific gastrointestinal symptoms or non-digestive disorders. | Edith Lahner Enzo Grossi Marco Intraligi Massimo Buscema Vito D Corleto Gianfranco Delle Fave Bruno Annibale | 2005 | World Journal of Gastroenterology2005,11,37: | 4 |
| 3 | 重组卡介苗表达的MalE蛋白T细胞表位的鉴定显示文摘目的 鉴定重组卡介苗表达的MalE蛋白T细胞表位。方法 用抗原提呈试验、T细胞增殖试验、ELISPOT试验和表位作图测试重组MalE蛋白的T细胞表位。结果 重组BCG MalE功能性表达了MalE蛋白的 4种H 2 d 限制性T细胞表位。结论 在 4种表位中 ,p6 8~ 82是重组MalE蛋白的主要T细胞表位 ,而其余 | 焦新安 Richard Lo-man Edith Driaud Sophie Burgaud Brigitte Gicquel Nathalie Winter Claude Leclerc 刘秀梵 | 2002 | 中华微生物学和免疫学杂志2002,22,1: | 3 |
| 4 | Type I Gastric Carcinoids: A Prospective Study on Endoscopic Management and Recurrence Rate显示文摘 | Merola Elettra Sbrozzi-vanni Andrea Panzuto Francesco D’ambra Giancarlo Di Giulio Emilio Pilozzi Emanuela Capurso Gabriele Lahner Edith Bordi Cesare Annibale Bruno Delle Fave Gianfranco | 2012 | Neuroendocrinology2012,,3: | 2 |
| 5 | 重组卡介苗感染树突细胞的研究显示文摘在体内外试验中 ,树突细胞 (DC)均能摄取表达大肠杆菌麦芽糖结合蛋白 (MalE)的重组卡介苗 (rBCG·MalE)。应用流式细胞术测得荧光标记的rBCG·MalE在体内感染DC的水平在 1 % 2 % ,与感染巨噬细胞 (MΦ)的水平相当。体外抗原提呈试验结果显示 ,DC和MΦ能吞噬、加工rBCG·MalE并向T细胞杂交瘤FBU·B1 1提呈MalE蛋白抗原表位 ,而在体内试验中 ,从rBCG·MalE免疫小鼠脾脏中纯化的DC ,可检测到MalE表位MHCⅡ复合物 ,而纯化的MΦs却测不到。这表明DC在起始抗分枝杆菌的免疫保护中发挥关键作用。 | 焦新安 Richard Lo-Man Pierre Guermonprez Edith Dériaud Brigitte Gicquel Nathalie Winter Claude Leclerc 刘秀梵 | 2002 | 扬州大学学报(农业与生命科学版)2002,23,1: | 2 |
| 6 | A comparison of postprandial and prepandial adminstration of insulin aspart in child and adolescants with type 1 diabetes 显示文摘 | THOMAS D JAN A EDITH S | 2003 | Diabetes Care2003,26,8: | 1 |
| 7 | P-glycoprotein is strongly expression in the luminal membranes of the endothelium of blood vessels in the brain显示文摘 | EDITH B MICHEL D LUCIAN G | 1997 | Biochem J1997,326,: | 1 |
| 8 | Rheology and morphology of polyester/thermoplastic flour blends显示文摘 | Florian D Edith P D Bruno V | 2014 | Journal of Applied Polymer Science2014,131,10: | 1 |
| 9 | Occurrence of gastric cancer and carcinoids in atrophic gastritis during prospective long-term follow up显示文摘 | Edith Lahner Gianluca Esposito Emanuela Pilozzi Flaminia Purchiaroni Vito D Corleto Emilio Di Giulio Bruno Annibale | 2015 | Scandinavian Journal of Gastroenterology2015,,7: | 1 |
| 10 | Ras pathway inhibition prevents neovascularization by repressing endothelial cell sprouting显示文摘 | Westenskow Peter D Kurihara Toshihide Aguilar Edith Scheppke Elizabeth L Moreno Stacey K Wittgrove Carli Marchetti Valentina Michael Iacovos P Anand Sudarshan Nagy Andras Cheresh David Friedlander Martin | 2013 | Journal of Clinical Investigation2013,,11: | 1 |
| 11 | The effect of ceftriaxone on the anaerobic bacterial flora and the bacterial enzymatic activity in the intestinal tract显示文摘 | G. W. Welling Ph. D. Geke J. Meijer-Severs M. S. Gé Helmus Edith Santen R. H. J. Tonk Hilly G. Vries- Hospers M. D. Ph. D. D. Waaij M. D. Ph. D | 1991 | Infection1991,,5: | 1 |
| 12 | A comparison of postprandial and prepandial adminstration of insulin aspart in child and adolescants with type 1 diabetes 显示文摘 | THOMAS D JAN A EDITH S | 2003 | Diabetes Care2003,26,8: | 1 |
| 13 | Citrate Kinetics in patients re- ceiving long- term hemodialysis therapy 显示文摘 | Edith B Kurt D Christian J | 2005 | American J Kidney Diseases2005,46,5: | 1 |
| 14 | Assessment of jugular blood oxygen and lactate inkices for detection of cerebral ischemia and prognosis显示文摘 | Francois Artru Frédéric Dailler Edith Burel | 2004 | J Neurosurg Anesthesiol2004,16,3: | 1 |
| 15 | Adolescent depression: a metasynthesis 显示文摘 | Edith D | 2006 | Journal of Pediatric Health Care2006,20,6: | 1 |
| 16 | Signal transducers and activators of transcription ( STAT ) signalingin patients with end-stage dilated cardiomyopathy 显示文摘 | Edith K Podewski D | 2003 | Circulation2003,107,: | 1 |
| 17 | Assessment ofjugular blood oxygen and lactate indices for detection ofcerebral ischemia and prognosis 显示文摘 | Francois A Frederic D Edith B | 2004 | J NeurosurgAnesthesiol2004,16,3: | 1 |
| 18 | Density Functional Theory Investigation of the Stereochemistry Effects on ^1H and ^13 C NMR Chemical Shifts of Poly(vinyl chloride) Oligomers显示文摘 | Philippe d' Antuono Edith Botek Benoit Champagne | 2005 | Chemical Physics Letters2005,411,: | 1 |
| 19 | In vivo assessment of skin electroporation using square wave pulses显示文摘 | NATHALIE D EDITH S | 2002 | J Controlled Release2002,79,13: | 1 |
| 20 | Identification of the angiogenic endothelial-cell growth factor-1/thymidine phosphorylase as apotential target for immunotherapy of cancer 显示文摘 | Elisabeth H S Willy M H Edith D M | 2006 | Blood2006,107,12: | 1 |