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| 1 | Hepatic steatosis is associated with an increased risk of carotid atherosclerosis显示文摘AIM: Although an association between helatic steatosis and vascular risk factors has been described, direct relationships between fatty liver and atherosclerosis have not yet been investigated. The aim of the present study has been to investigate those relationships.METHODS: The Study of Health in Pomerania examined a random population sample aged between 20 and 79 years.A study population of 4 222 subjects without hepatitis B and C infections and without liver cirrhosis was available for the present analysis. Hepatic steatosis was defined sonographically and intima-media thickness (IMT) as well as plaque prevalence were estimated by carotid ultrasound.RESULTS: The prevalence rate of hepatic steatosis was 29.9%. Among subjects aged ≥45 years, an association between hepatic steatosis and IMT of the carotid arteries was found in bivariate analysis, but not after adjustment for atherosclerotic risk factors. Individuals with fatty liver had more often carotid plaques than persons without fatty liver (plaque prevalence rate 76.8% vs 66.6%; P<0.001).This association persisted after adjustment for confounding factors and was predominantly present in subjects with no to mild alcohol consumption.CONCLUSION: There is an independent association between hepatic steatosis and carotid atherosclerotic plaques. Metabolic changes due to nonalcoholic fatty liver disease may explain this relationship. | Henry V(o|¨)lzke Daniel M.Robinson Volker Kleine Roland Deutscher Wolfgang Hoffmann Jan Lüdemann Ulf Schminke Christof Kessler Ulrich John | 2005 | World Journal of Gastroenterology2005，11，12： | 29 |
| 2 | 一种采用洁净空气绝缘和真空灭弧技术的环境友好型GIS的研究和应用显示文摘对于高压产品尤其是GIS/AIS开关,SF_6一直被作为主要的灭弧和绝缘介质广泛使用。但因为其非常高的全球变暖潜能(GWP=23 900),在过去几十年人们从没停止过对其替代气体的研究和寻找工作。近年氟化腈(如:C4-PFN即C4F7N)和氟代酮(如:C5-PFK即C5F10O)气体及其混合气体作为潜在的SF_6替代气体受到关注和初步应用;同时采用基于真空灭弧室灭弧配合洁净空气绝缘的GIS/AIS开关产品上也被开发并有了实际应用。文中简单总结了现有SF_6替代气体方案的技术现状,并重点介绍一种基于洁净空气绝缘和真空灭弧技术、不采用SF_6和任何氟类气体的GIS产品在研发过程中的一些关键技术,试验发现和最终应用情况。首先通过洁净空气在GIS中不同工况下的绝缘击穿试验和典型缺陷下的局放试验确立该新型GIS的尺寸参数标准;其次比较了GIS隔离开关和接地开关在洁净空气、C4-PFN混合气体、C5-PFK混合气体以及SF_6气体等不同工况下的小电流开合性能,并确定了洁净空气的相关开合特性和相对的优缺点;然后描述了为了满足高压断路器性能对真空灭弧室关键技术的相关改进情况;此外还从环境、安全和运维角度,对使用上述几种气体的开关进行了优劣势评估和讨论;最后结合该类新型开关设备的现场运行经验,认为基于洁净空气绝缘和真空灭弧技术的环境友好型GIS是理想的SF_6 GIS的替代产品。 | 李德军 沈威 KUSCHEL M DEMANN R | 2019 | 高压电器2019，55，2： | 15 |
| 3 | 前列腺药代动力计量及血流量参数MRI组织特性与组织学的对照性研究显示文摘目的前瞻性对照研究药代动力学MR影像参数与组织学的平均血管密度(MVD)、平均血管面积(MVA)及平均间质面积(MIA)的相关性,明确这些参数能否鉴别前列腺癌、慢性前列腺炎与正常前列腺组织。材料与方法此项研究由学术委员会批准,所有病人均签署了知情同意书。35例活检证实的前列腺癌病人接受了1.5TMR动态对比剂增强预反转双对比梯度回波序列(时间分辨率1.65s)扫描,计算血容量、间质容积与血流量。 | T.Franiel L.Lüdemann B.Rudolph H.Rehbein C.Stephan M.Taupitz 唐光健 | 2009 | 国际医学放射学杂志2009，32，5： | 8 |
| 4 | Excluding infection through procalcitonin testing improves outcomes of congestive heart failure patients presenting with acute respiratory symptoms: Results from the randomized ProHOSP trial显示文摘 | Philipp Schuetz Alexander Kutz Eva Grolimund Sebastian Haubitz Désirée Demann Alaadin V?geli Fabienne Hitz Mirjam Christ-Crain Robert Thomann Claudine Falconnier Claus Hoess Christoph Henzen Robert J. Marlowe Werner Zimmerli Beat Mueller | 2014 | International Journal of Cardiology2014，，3： | 2 |
| 5 | Detailed study of the composition of hydrogenated SiNx layers for high-quality silicon surface passivation显示文摘 | M(A)CKEL H LūDEMANN R | 2002 | J Appl Phys2002，92，： | 1 |
| 6 | Identifica-tion and functional characterization of thioredoxin from Trypanoso-ma brucei brucei显示文摘 | Reckenfelderbumer N Lüdemann H Schmidt H | 2000 | J Biol Chem2000，275，11： | 1 |
| 7 | Post-discharge surgical wound infection:what is to be done显示文摘 | Lüdemann CM Pfeffer F | | 0，，45： | 1 |
| 8 | Self-diffusion in fluid carbon dioxide at high pressures显示文摘 | Groβ T Buchhanser J Lüdemann H D | | 0，，11： | 1 |
| 9 | Study of Health in Pomerania (SHIP): A health examination survey in an east German region: Objectives and design显示文摘 | Prof. Dr. Ulrich John Elke Hensel Jan Lüdemann Marion Piek Sybille Sauer Christiane Adam Gabriele Born Dietrich Alte Eberhard Greiser Ursula Haertel Hans-Werner Hense Johannes Haerting Stefan Willich Christof Kessler | 2001 | Sozial - und Pr?ventivmedizin SPM2001，，3： | 1 |
| 10 | Do position and soft tissue affect distraction vector? An in vitro investigation显示文摘 | Demann ET Haug RH | 2002 | J Oral Maxillofac Surg2002，60，2： | 1 |
| 11 | Diagnosis of periprosthetic hip infections显示文摘 | Lüdemann C M Schütze N Rudert M | 2015 | Oper Orthop Traumatol2015，27，3： | 1 |
| 12 | Study of Health in Pomerania (SHIP): A health examination survey in an east German region: Objectives and design显示文摘 | Prof. Dr. Ulrich John Elke Hensel Jan Lüdemann Marion Piek Sybille Sauer Christiane Adam Gabriele Born Dietrich Alte Eberhard Greiser Ursula Haertel Hans-Werner Hense Johannes Haerting Stefan Willich Christof Kessler | 2001 | Sozial - und Pr?ventivmedizin SPM2001，，3： | 1 |
| 13 | The Prevalence of Undiagnosed Thyroid Disorders in a Previously Iodine-Deficient Area显示文摘 | Volzke H L Q demann J Robinson D M | 2003 | Thyroid2003，13，8： | 1 |
| 14 | Spatial changes in the bacterial community structure along a vertical oxygen gradient in flooded paddy soil cores显示文摘 | Lüdemann H Arth I Liesack W | 2000 | Applied and Environmental Microbiology2000，66，2： | 1 |
| 15 | 查看详情显示文摘 | Chowdhary J Cairns B Mishchenko M I Hobbs P Cota G Re- demann J Rutledge K Holben B N Russel E | | 0，，： | 1 |
| 16 | Ki-67 protein is associated with ribosomal RNA transcription in quiescent and proliferating cells显示文摘 | Bullwinkel J Baron-Lühr B Lüdemann A | 2006 | J Cell Physiol2006，206，3： | 1 |
| 17 | Evaluation of Normal Prostate Tissue, Chronic Prostatitis, and Prostate Cancer by Quantitative Perfusion Analysis Using a Dynamic Contrast-Enhanced Inversion-Prepared Dual-Contrast Gradient Echo Sequence显示文摘 | Tobias Franiel Lutz Lüdemann Birgit Rudolph Hagen Rehbein Andrea Staack Matthias Taupitz Daniel Prochnow Dirk Beyersdorff | 2008 | Investigative Radiology2008，，： | 1 |
| 18 | Self-diffusion in fluid carbon dioxide at high pressures显示文摘 | Gross T Buchhauser J Lüdemann H D | | 0，，11： | 1 |
| 19 | Patient preference and tolerability of a DPP-4 inhibitor versus a GLP-1 analog in patients with type 2 diabetesmellitus inadequately controlled with metformin:a 24-week,randomized,multicenter,crossover study显示文摘 | Lüdemann J Dütting ED Dworak M | 2015 | Ther Adv Endocrinol Metab2015，6，4： | 1 |
| 20 | Cervical artery dissection—clinical features, risk factors, therapy and outcome in 126 patients显示文摘 | Rainer Dziewas MD Carsten Konrad Bianca Dr?ger Stefan Evers Michael Besselmann Peter Lüdemann Gregor Kuhlenb?umer Florian St?gbauer E. Bernd Ringelstein | 2003 | Journal of Neurology2003，，10： | 1 |
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