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| 1 | Evolution of transanal total mesorectal excision for rectal cancer:From top to bottom显示文摘The gold standard for curative treatment of locally advanced rectal cancer involves radical resection with a total mesorectal excision(TME). TME is the most effective treatment strategy to reduce local recurrence and improve survival outcomes regardless of the surgical platform used. However, there are associated morbidities, functional consequences, and quality of life(QoL) issues associated with TME; these risks must be considered during the modern-day multidisciplinary treatment for rectal cancer. This has led to the development of new surgical techniques to improve patient, oncologic, and QoL outcomes. In this work, we review the evolution of TME to the transanal total mesorectal excision(TaTME) through more traditional minimally invasive platforms. The review the development, safety and feasibility, proposed benefits and risks of the procedure, implementation and education models, and future direction for research and implementation of the TaTME in colorectal surgery. While satisfactory short-term results have been reported, the procedure is in its infancy, and long term outcomes and definitive results from controlled trials are pending.As evidence for safety and feasibility accumulates,structured training programs to standardize teaching,training, and safe expansion will aid the safe spread of the TaTME. | Sameh Hany Emile F Borja de Lacy Deborah Susan Keller Beatriz Martin-Perez Sadir Alrawi Antonio M Lacy Manish Chand | 2018 | World Journal of Gastrointestinal Surgery2018，10，3： | 18 |
| 2 | Review of 500 single incision laparoscopic colorectalsurgery cases-Lessons learned显示文摘Single incision laparoscopic surgery(SILS) is a minimally invasive platform with specific benefits over traditional multiport laparoscopic surgery. The safety and feasibility of SILS has been proven, and the applications continue to grow with experience. After 500 cases at a high-volume, single-institution, we were able to standardize instrumentation and operative steps, as well as develop adaptations in technique to help overcome technical and ergonomic challenges. These technical adaptations have allowed the successful application of SILS to technically difficult patient populations, such as pelvic cases, inflammatory bowel disease cases, and high body mass index patients. This review is a frame of reference for the application and wider integration of the single incision laparoscopic platform in colorectal surgery. | Deborah S Keller Juan R Flores-Gonzalez Sergio Ibarra Eric M Haas | 2016 | World Journal of Gastroenterology2016，22，2： | 8 |
| 3 | Review of single incision laparoscopic surgery in colorectal surgery显示文摘As surgical techniques continue to move towards less invasive techniques,single incision laparoscopic surgery(SILS),a hybrid between traditional multiport laparoscopy and natural orifice transluminal endoscopic surgery,was introduced to further the enhanced outcomes of multiport laparoscopy. The safety and feasibility of SILS for both benign and malignant colorectal disease has been proven. SILS provides the potential for improved cosmesis,postoperative pain,recovery time,and quality of life at the drawback of higher technical skill required. In this article,we review the history,describe the available technology and techniques,and evaluate the benefits and limitations of SILS for colorectal surgery in the published literature. | Nisreen Madhoun Deborah S Keller Eric M Haas | 2015 | World Journal of Gastroenterology2015，21，38： | 8 |
| 4 | Regulation of epithelium-specific Ets-like factors ESE-1 and ESE-3 in airway epithelial cells: potential roles in airway inflammation显示文摘航线发炎是许多呼吸障碍的特点,例如气喘和膀胱的纤维变性。在发炎触发的航线基因表示的变化在这些疾病的致病起一个关键作用。基因连接研究建议 ESE-2 和 ESE-3,编码上皮特定的 Ets-domain-containing 抄写因素,是候选人气喘危险性基因。我们这里报导 et 家庭抄写因素 ESE-1 的另一个成员的表示,以及 ESE-3,起来在支气管的上皮的房间线由煽动性的 cytokines interleukin-1beta (IL-1beta ) 和肿瘤坏死 factor-alpha (TNF-alpha ) 调整了。有 IL-1beta 和 TNF-alpha 的这些房间的处理为 ESE-1 和 ESE-3 导致了信使 rna 表示的戏剧的增加。我们证明导致的表示被抄写因素 NF-kappaB 的激活调停。我们描绘了 ESE-1 和 ESE-3 倡导者并且识别了为导致 cytokine 的表达式被要求的 NF-kappaB 有约束力的序列。另外,我们也表明那 ESE-1 在上面调整 ESE-3 表示, down 由 cytokines 调整它的自己的正式就职。最后,我们在 Elf3 显示出那(对人的 ESE-1 相应) 猛烈老鼠,煽动性的 cytokine interleukin-6 (IL-6 ) 的表示是调整的 down。我们的调查结果建议 ESE-1 和 ESE-3 在航线发炎起一个重要作用。 | Jing Wu Rongqi Duan Huibi Cao Deborah Field Catherine M Newnham David R Koehler Noe Zamel Melanie A Pritchard Paul Hertzog Martin Post A Keith Tanswell Jim Hu | 2008 | Cell Research2008，18，6： | 6 |
| 5 | The role of serotonin receptor alleles and environmental stressors in the development of post‐concussive symptoms after pediatric mild traumatic brain injury显示文摘 | Kim Smyth Sandeep S Sandhu Susan Crawford Deborah Dewey Jillian Parboosingh Karen M Barlow | 2014 | Dev Med Child Neurol2014，，1： | 2 |
| 6 | Characterisation of programmed cell death during aerenchyma formation induced by ethylene or hypoxia in roots of maize 显示文摘 | Gunawardena AN Deborah M | 2001 | Planta2001，212，： | 1 |
| 7 | Identification of △^5-desaturase from mortierella alpina by heterologous extrusion in bakers' yeast and canola显示文摘 | Deborah S K Jennifer M T Huang Y S | 1998 | J Biol Chem1998，273，29： | 1 |
| 8 | Rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisolone in patients with newly diagnosed diffuse large B-cell non-Hodgkin lymphoma: a phase 3 comparison of dose intensification with 14-day versus 21-day cycles显示文摘 | David Cunningham Eliza A Hawkes Andrew Jack Wendi Qian Paul Smith Paul Mouncey Christopher Pocock Kirit M Ardeshna John A Radford Andrew McMillan John Davies Deborah Turner Anton Kruger Peter Johnson Joanna Gambell David Linch | 2013 | The Lancet2013，，9880： | 1 |
| 9 | Adolescents' concern for privacy when using the internet- an empirical analysis of predictors and relationships with privacy-protecting behaviors 显示文摘 | Deborah M M Richard D | 2007 | Family and Consumer Sciences Research Journal2007，35，3： | 1 |
| 10 | Radiation-induced epigenetic DNA methylation modification of radiation-response pathways显示文摘 | Deborah A Antwih Kristina M Gabbara Wayne D Lancaster Douglas M Ruden Steven P Zielske | 2013 | Epigenetics2013，，8： | 1 |
| 11 | “Tailored”organometallics as precursors for the chemicalvapor deposition of high-purity palladium and platinum thinfilms显示文摘 | John E Gozum Deborah M Pollina James A Jensen | 1988 | J Am Chem Soc1988，110，： | 1 |
| 12 | The role of endoscopy in Barrett’s esophagus and other premalignant conditions of the esophagus显示文摘 | John A. Evans Dayna S. Early Norio Fukami Tamir Ben-Menachem Vinay Chandrasekhara Krishnavel V. Chathadi G. Anton Decker Robert D. Fanelli Deborah A. Fisher Kimberly Q. Foley Joo Ha Hwang Rajeev Jain Terry L. Jue Khalid M. Khan Jenifer Lightdale Phyllis M | 2012 | Gastrointestinal Endoscopy2012，，6： | 1 |
| 13 | Mental health during pregnancy : A study comparing asian, caucasian and native hawaiian women 显示文摘 | DEBORAH G LESLIE M LEIGHANN F | 2007 | Maternal and Child Health Journal2007，11，3： | 1 |
| 14 | Real-time reverse transeription-polymerase chain reaction assays for the detection and differentiation of North American swine influenza viruses 显示文摘 | Jurgen A R Kelly M L Deborah F C | 2004 | J Vet Diagn Invest2004，16，： | 1 |
| 15 | Natriuretic Peptides,Their Receptors and cGMP-dependent Signa-ling Functions显示文摘 | Lincoln R P Sarah A H Deborah M D | 2005 | Endocrine Reviews2005，16，： | 1 |
| 16 | Influenza vaccination: an emerging opportunity to prevent cardio vascular disease显示文摘 | Mohammad M Silvio L Deborah V | 2004 | International Congress Series2004，126，3： | 1 |
| 17 | The Prevalence of Depression in a Cohort of the very Dlderly显示文摘 | Deborah M G Claire B Eugene S P | 1995 | Journal of Affective Disorders1995，34，： | 1 |
| 18 | A political theory of corporate tax- ation显示文摘 | Arlen J and Deborah M W | 1995 | Yale Law Journal1995，105，1： | 1 |
| 19 | Imaging of Adnexal Masses in Pregnancy显示文摘 | Gloria Chiang B A Deborah Levine M D | | 0，，： | 1 |
| 20 | Global burden of hepatitis C:considerations for healthcare providers in the United States显示文摘 | AverhoffFrancisco M Glass Nancy Holtzman Deborah | 2012 | Clin Infect Dis2012，，： | 1 |
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