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| 1 | 乳腺癌的分子分类及其临床应用显示文摘乳腺癌是一组异质性很高的肿瘤。当前在乳腺癌的诊断和治疗上已取得了重要进展,包括乳腺摄片筛查、化疗方案以及针对ER和HER2的内分泌治疗和靶向治疗,已开始降低了乳腺癌的病死率。然而在确定哪些患者对哪种治疗最有效,以及哪些患者最易复发等方面取得的成效很小。目前临床医师面临的主要挑战是怎样最好地评估和预测肿瘤的临床过程和患者的临床结局。 | 唐平 魏兵 David G. Hicks Kristin Skinner 步宏 | 2009 | 中华病理学杂志2009，38，1： | 24 |
| 2 | ^(18)F-FDG PET/CT显像在鼻咽癌分期与疗效监测中的临床应用价值显示文摘背景与目的:18F-脱氧葡萄糖(fluorine-18 fluorodeoxyglucose,18F-FDG)PET/CT显像可明显提高肺癌、食管癌等多种肿瘤的诊断、分期与疗效监测的准确性,有助于更准确地制定治疗方案。本研究探讨全身18F-FDG PET/CT显像在鼻咽癌首次分期、再分期及疗效监测中的临床应用价值。方法:回顾性分析澳大利亚Peter MacCallum肿瘤中心2002年2月至2005年12月43例鼻咽癌患者的18F-FDG PET/CT全身扫描报告,根据临床资料、病理结果及临床随访结果,计算18F-FDG PET/CT与传统影像学检查CT、MRI的准确性、特异性、灵敏度、阳性预测值与阴性预测值,并对结果进行比较和分析。结果:18F-FDG PET/CT诊断鼻咽癌总的准确率、敏感性、特异性、阳性预测值与阴性预测值分别为95.3%、100.0%、85.7%、93.8%、100.0%,传统影像学检查CT、MRI分别为65.5%、79.4%、64.7%、81.8%、57.9%。18F-FDGPET/CT诊断结果使2例首次分期、7例再分期患者治疗方案得到改变,并影响1例首次分期和3例再分期患者治疗方案的制定;在疗效监测组中,指导医生修改治疗方案共11例(其中5例为原则性的修改)。18F-FDG PET/CT检测到2例第二原发肿瘤,1例是甲状腺癌,1例是低度恶性胃癌。结论:18F-FDG PET/CT全身显像对鼻咽癌N、M分期与疗效监测的临床作用可能优于CT、MR检查。 | 王国慧 Eddie W. F. Lau Ramdave Shakher David S. Binns Annette Hogg Elizabeth Drummond Rodney J. Hicks | 2007 | 癌症2007，26，6： | 19 |
| 3 | A 3D morphometric perspective for facial gender analysis and classification using geodesic path curvature features显示文摘The relationship between the shape and gender of a face, with particular application to automatic gender classification, has been the subject of significant research in recent years. Determining the gender of a face, especially when dealing with unseen examples, presents a major challenge. This is especially true for certain age groups, such as teenagers, due to their rapid development at this phase of life. This study proposes a new set of facial morphological descriptors,based on 3D geodesic path curvatures, and uses them for gender analysis. Their goal is to discern key facial areas related to gender, specifically suited to the task of gender classification. These new curvature-based features are extracted along the geodesic path between two biological landmarks located in key facial areas.Classification performance based on the new features is compared with that achieved using the Euclidean and geodesic distance measures traditionally used in gender analysis and classification. Five different experiments were conducted on a large teenage face database(4745 faces from the Avon Longitudinal Study of Parents and Children) to investigate and justify the use of the proposed curvature features. Our experiments show that the combination of the new features with geodesic distances provides a classification accuracy of 89%. They also show that nose-related traits provide the most discriminative facial feature for gender classification, with the most discriminative features lying along the 3D face profile curve. | Hawraa Abbas Yulia Hicks David Marshall Alexei I.Zhurov StephenRichmond | 2018 | Computational Visual Media2018，4，1： | 5 |
| 4 | Parametrically constrained geometry relaxations for high-throughput materials science显示文摘Reducing parameter spaces via exploiting symmetries has greatly accelerated and increased the quality of electronic-structure calculations.Unfortunately,many of the traditional methods fail when the global crystal symmetry is broken,even when the distortion is only a slight perturbation(e.g.,Jahn-Teller like distortions).Here we introduce a flexible and generalizable parametric relaxation scheme and implement it in the all-electron code FHI-aims.This approach utilizes parametric constraints to maintain symmetry at any level.After demonstrating the method’s ability to relax metastable structures,we highlight its adaptability and performance over a test set of 359 materials,across 13 lattice prototypes.Finally we show how these constraints can reduce the number of steps needed to relax local lattice distortions by an order of magnitude.The flexibility of these constraints enables a significant acceleration of high-throughput searches for novel materials for numerous applications. | Maja-Olivia Lenz Thomas A.R.Purcell David Hicks Stefano Curtarolo Matthias Scheffler Christian Carbogno | 2019 | npj Computational Materials2019，，1： | 2 |
| 5 | AFLOW-XtalFinder:a reliable choice to identify crystalline prototypes显示文摘The accelerated growth rate of repository entries in crystallographic databases makes it arduous to identify and classify their prototype structures.The open-source AFLOW-XtalFinder package was developed to solve this problem.It symbolically maps structures into standard designations following the AFLOW Prototype Encyclopedia and calculates the internal degrees of freedom consistent with the International Tables for Crystallography.To ensure uniqueness,structures are analyzed and compared via symmetry,local atomic geometries,and crystal mapping techniques,simultaneously grouping them by similarity.The software(i)distinguishes distinct crystal prototypes and atom decorations,(ii)determines equivalent spin configurations,(iii)reveals compounds with similar properties,and(iv)guides the discovery of unexplored materials.The operations are accessible through a Python module ready for workflows,and through command line syntax.All the 4+million compounds in the AFLOW.org repositories are mapped to their ideal prototype,allowing users to search database entries via symbolic structure-type.Furthermore,15,000 unique structures—sorted by prevalence—are extracted from the AFLOW-ICSD catalog to serve as future prototypes in the Encyclopedia. | David Hicks Cormac Toher Denise CFord Frisco Rose Carlo De Santo Ohad Levy Michael J.Mehl Stefano Curtarolo | 2021 | npj Computational Materials2021，，1： | 2 |
| 6 | MUC17, a Novel Membrane-Tethered Mucin显示文摘 | James R. Gum Suzanne C. Crawley James W. Hicks David E. Szymkowski Young S. Kim | 2002 | Biochemical and Biophysical Research Communications2002，，3： | 1 |
| 7 | Impact of C-arm CT on Hepatic Arterial Interventions for Hepatic Malignancies显示文摘 | Michael J. Wallace Ravi Murthy Paresh P. Kamat Teri Moore Sujaya H. Rao Joe Ensor Sanjay Gupta Kamran Ahrar David C. Madoff Stephen E. McRae Marshall E. Hicks | 2007 | Journal of Vascular and Interventional Radiology2007，，12： | 1 |
| 8 | Low back pain显示文摘 | Swink Hicks G David N Duddleseton | 2002 | Am J Mad Sci2002，324，： | 1 |
| 9 | Cornfiber gum : New structure/function relationships for this po-tential beverage flavor stabilizer 显示文摘 | Madhav P Yadav David B Johnston Kevin B Hicks | 2009 | Food Hydrocolloids2009，23，6： | 1 |
| 10 | Recommendations for Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer: American Society of Clinical Oncology/College of American Pathologists Clinical Practice Guideline Update显示文摘 | Antonio C. Wolff M. Elizabeth H. Hammond David G. Hicks Mitch Dowsett Lisa M. McShane Kimberly H. Allison Donald C. Allred John M.S. Bartlett Michael Bilous Patrick Fitzgibbons Wedad Hanna Robert B. Jenkins Pamela B. Mangu Soonmyung Paik Edith A. Perez Mi | 2013 | Journal of Clinical Oncology2013，，： | 1 |
| 11 | Low back pain显示文摘 | SWINK HICKS G DAVID W DIDDLESETON | 2002 | Am J Mad Sci2002，324，： | 1 |
| 12 | Pretreatment of wet-milled com fiber to improve recovery of com fiber oil and phytosterols 显示文摘 | Vijay Singh David B Johnston Robert A Moreau Kevin B Hicks Bruce S Dien R J Bothast | 2003 | Cereal Chem2003，80，9： | 1 |
| 13 | Mechano- catalysis for biomass-derived chemicals and fuels 显示文摘 | Sandra M Hick Carolin Griebel David T Restrepo | 2010 | Green Chem2010，3，： | 1 |
| 14 | Low back pain显示文摘 | Swink Hicks G David N DuddIeseton et al | 2002 | The American Journal of The Medical Sciences2002，324，4： | 1 |
| 15 | A comparison of commercial enzymes for the aqueous enzymatic extraction of corn oil from corn germ显示文摘 | Robert A. Moreau David B. Johnston Michael J. Powell Kevin B. Hicks | 2004 | Journal of the American Oil Chemists’ Society2004，，11： | 1 |
| 16 | Bio-oil and bio-char production from corn cobs and stover by fast pyrolysis显示文摘 | Charles A. Mullen Akwasi A. Boateng Neil M. Goldberg Isabel M. Lima David A. Laird Kevin B. Hicks | 2009 | Biomass and Bioenergy2009，，1： | 1 |
| 17 | Low Back Pain显示文摘 | G. Swink Hicks David N. Duddleston Lori D. Russell Honey E. Holman Jinna M. Shepherd C. Andrew Brown | 2002 | The American Journal of the Medical Sciences2002，，4： | 1 |
| 18 | Corn fiber gum:new structure/function relationship for this potential beverage flavor stabilizer显示文摘 | Madhav P Yadav David B Johnston Kevin B Hicks | | 0，，23： | 1 |
| 19 | Low back pain 显示文摘 | Swink Hicks G David N Duddleseton | 2002 | The American Journal of The Medical Sciences2002，324，4： | 1 |
| 20 | A three-dimensional in-vitro model for the study of peritoneal tumour metastasis显示文摘 | David G. Jayne Ronan O’Leary Andrew Gill Adrian Hick Pierre J. Guillou | 1999 | Clinical and Experimental Metastasis1999，，6： | 1 |
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