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| 1 | 在有分散的胃的息肉的病人的 colorectal 息肉的风险: 盒子控制研究显示文摘 AIM:To assess the risk of colonic polyps,adenomas and advanced neoplastic lesions(ANL) in patients with sporadic gastric polyps,especially those with fundic gland polyps(FGP).METHODS:Clinical records of patients who had performed an upper and a lower digestive endoscopy between September 2007 and August 2008 were retrospectively analyzed.A case-control study was carried out,calling patients with gastric polyps as 'cases' and patients without gastric polyps as 'controls'.The risk of colonic polyps,adenomas and ANL(villous component ≥ 25%,size ≥ 10 mm,or high grade dysplasia) was assessed [odds ratio(OR) and its corresponding 95%CI].RESULTS:Two hundred and forty seven patients were analyzed:78 with gastric polyps(cases) and 169 without gastric polyps(controls).Among the cases,the majority of gastric polyps were FGP(80%,CI:69-88) and hyperplastic(20%,CI:12-31);25% had colonic polyps(25% hyperplastic and 68% adenomas,from which 45% were ANL).Among the controls,20% had colonic polyps(31% hyperplastic and 63% adenomas,from which 41% were ANL).The patients with sporadic FGP had an OR of 1.56(CI:0.80-3.04) for colonic polyps,an OR of 1.78(CI:0.82-3.84) for colonic adenomas,and an OR of 0.80(CI:0.21-2.98) for ANL.Similar results were found in patients with gastric polyps in general.CONCLUSION:The results of this study did not show more risk of colorectal adenomas or ANL neither in patients with sporadic gastric polyps nor in those with FGP. | Daniel Gustavo Cimmino José Manuel Mella Pablo Luna Raquel González Lisandro Pereyra Carolina Fischer Adriana Mohaidle Beatriz Vizcaino Mario Andres Medrano Adrián Hadad Silvia Pedreira Luis Boerr | 2013 | World Journal of Gastrointestinal Endoscopy2013,5,5: | 12 |
| 2 | Coexpression of receptor-tyrosine-kinases in gastric adenocarcinoma-a rationale for a molecular targeting strategy?显示文摘AIM: To define the (co-)expression pattern of target receptor-tyrosine-kinases (RTK) in human gastric adenocarcinoma. METHODS: The (co-)expression pattern of VEGFR1-3,PDGFRα/b and EGFR1 was analyzed by RT-PCR in 51 human gastric adenocarcinomas. In addition,IHC staining was applied for confirmation of expression and analysis of RTK localisation. RESULTS: The majority of samples revealed a VEGFR1 (98%),VEGFR2 (80%),VEGFR3 (67%),PDGFRα (82%) and PDGFRβ(82%) expression,whereas only 62% exhibited an EGFR1 expression. 78% of cancers expressed at least four out of six RTKs. While VEGFR1-3 and PDGFRα revealed a predominantly cytoplasmatic staining in tumor cells,accompanied by an additional nuclear staining for VEGFR3 ,EGFR1 was almost exclusively detected on the membrane of tumor cells. PDGFRβ was restricted to stromal pericytes,which also depicted a PDGFRα expression.receptor-tyrosine-kinases coexpression in gastric adenocarcinoma and might therefore encourage an application of multiple-target RTK-inhibitors within a combination therapy. | Daniel Drescher Markus Moehler Ines Gockel Kirsten Frerichs Annett Müller Friedrich Dünschede Thomas Borschitz Stefan Biesterfeld Martin Holtmann Thomas Wehler Andreas Teufel Kerstin Herzer Thomas Fischer Martin R Berger Theodor Junginger Peter R Galle Carl C Schimanski | 2007 | World Journal of Gastroenterology2007,13,26: | 4 |
| 3 | Influence of experimental soil disturbances on the diversity of plants in agricultural grasslands显示文摘Aims and Methods Disturbance is supposed to play an important role for biodiversity and ecosystem stability as described by the intermediate disturbance hypoth-esis(IDH),which predicts highest species richness at intermediate levels of disturbances.In this study,we tested the effects of artificial soil distur-bances on diversity of annual and perennial vascular plants and bryo-phytes in a field experiment in 86 agricultural grasslands differing in land use in two regions of Germany.On each grassland,we implemented four treatments:three treatments differing in application time of soil dis-turbances and one control.One year after experimental disturbance,we recorded vegetation and measured biomass productivity and bare ground.We analysed the disturbance response taking effects of region and land-use-accompanied disturbance regimes into account.Important Findings Region and land-use type strongly determined plant species rich-ness.Experimental disturbances had small positive effects on the species richness of annuals,but none on perennials or bryophytes.Bare ground was positively related to species richness of bryophytes.However,exceeding the creation of 12%bare ground further distur-bance had a detrimental effect on bryophyte species richness,which corresponds to the IDH.As biomass productivity was unaffected by disturbance our results indicate that the disturbance effect on spe-cies richness of annuals was not due to decreased overall produc-tivity,but rather due to short-term lowered inter-and intraspecific competition at the newly created microsites.Generally,our results highlight the importance of soil disturbances for species richness of annual plants and bryophytes in agricultural grasslands.However,most grasslands were disturbed naturally or by land-use practices and our additional experimental soil dis-turbances only had a small short-term effect.Overall,total plant diversity in grasslands seemed to be more limited by the availabil-ity of propagules rather than by suitable microsites for germination.Thus,nature conservation efforts to increase grassland diversity should focus on overcoming propagule limitation,for instance by additional sowing of seeds,while the creation of additional open patches by disturbance might only be appropriate where natural disturbances are scarce. | Jörg Müller Johannes Heinze Jasmin Joshi Steffen Boch Valentin H.Klaus Markus Fischer Daniel Prati | 2014 | Journal of Plant Ecology2014,7,6: | 3 |
| 4 | Ionic liquids for extraction of metals and metal containing compounds from communal and industrial waste water显示文摘 | Lisa Fischer Thomas Falta Gunda Koellensperger Anja Stojanovic Daniel Kogelnig Markus Galanski Regina Krachler Bernhard K. Keppler Stephan Hann | 2011 | Water Research2011,,15: | 2 |
| 5 | 低成本姿态控制敏感器的新家族显示文摘本文介绍满足人造卫星姿态测量要求的新一代光学敏感器的发展状况。这些敏感器包括:一种新型两轴全静态红外地球敏感器(现已通过鉴定)。它用来测量三轴稳定卫星相对于地平线的俯仰与滚动姿态;一种新型多功能、全自动、低成本的星跟踪器。这种星跟踪器(现已通过鉴定)为姿态控制分系统提供三轴姿态和卫星角速度信息;一种用来测量卫星俯仰与滚动姿态角的新型太阳敏感器。它质量很轻,价格很便宜。 | Daniel Fischer Rene.Priam Ludovic Blarre Didier Vilaire 郑克隆 | 2003 | 控制工程(北京)2003,,2: | 1 |
| 6 | Mechatronic semi-active and active vehicle suspensions显示文摘 | Daniel Fischer Rolf Isermann | 2003 | Control Engineering Practice2003,8,: | 1 |
| 7 | Expression of PEPT2 peptide transporter mRNA and protein in glial cells of rat dorsal root ganglia显示文摘 | Groneberg DA Doring F Nickolaus M Daniel H Fischer A | 2001 | Neurosci Lett2001,304,3: | 1 |
| 8 | Peptide transport in the mammary gland : expression and distribution of PEPT2 mRNA and protein显示文摘 | Groneherg DA Daring F Theis S Nickolaus M Fischer A Daniel H | 2002 | Am J Physiol Endocrinol Metab2002,282,5: | 1 |
| 9 | Frequency, Timing, and Predictors of Neurological Dysfunction in the Nonmyelopathic Patient With Cervical Spinal Cord Compression, Canal Stenosis, and/or Ossification of the Posterior Longitudinal Ligament显示文摘 | Jefferson R. Wilson Sean Barry Dena J. Fischer Andrea C. Skelly Paul M. Arnold K. Daniel Riew Christopher I. Shaffrey Vincent C. Traynelis Michael G. Fehlings | 2013 | 2013 (22S)2013,,22: | 1 |
| 10 | High-Resolution Multiprojector Display Walls 显示文摘 | Daniel R Schikore Richard A Fischer | 2000 | IEEE Computer Graphics and Applications (S0272-1716)2000,20,4: | 1 |
| 11 | Liver Fat Quantification by Dual-echo MR Imaging Outperforms Traditional Histopathological Analysis显示文摘 | Michael A. Fischer Dimitri A. Raptis Matteo Montani Rolf Graf Pierre-Alain Clavien Daniel Nanz Hatem Alkadhi Hans Scheffel | 2012 | Academic Radiology2012,,10: | 1 |
| 12 | Prime-boost immunization using DNA vaccine and re- combinant orf virus protects pigs against pseudorabies virus (Herpes suid 1)显示文摘 | Daniel Dory Timo Fischer Veronique Beven | 2006 | Vaccine2006,24,: | 1 |
| 13 | Localization of the peptide transporter PEPT2 in the lung: implication for pulmonary oligopeptide uptake显示文摘 | Groneberg DA Nickolaus M Springer J Doring F Daniel H Fischer A | 2001 | Am J Pathol2001,158,2: | 1 |
| 14 | Th1 and Th2 cells are required for both eosinophil- and neutrophil-associated airway inflammatory responses in mice显示文摘 | Romy Fischer Daniel Tomé Jerry R. McGhee Prosper N. Boyaka | 2007 | Biochemical and Biophysical Research Communications2007,,1: | 1 |
| 15 | High-voltage pixel detectors in commercial CMOS technologies for ATLAS, CLIC and Mu3e experiments显示文摘 | Ivan Peri? Peter Fischer Christian Kreidl Hong Hanh Nguyen Heiko Augustin Niklaus Berger Moritz Kiehn Ann-Kathrin Perrevoort André Sch?ning Dirk Wiedner Simon Feigl Timon Heim Lingxin Meng Daniel Münstermann Mathieu Benoit Dominik Dannheim Frederic Bompar | 2013 | Nuclear Inst. and Methods in Physics Research, A2013,,: | 1 |
| 16 | Expression of PEPT2 peptide transporter mRNA and protein in glial cells of rat dorsal root ganglia显示文摘 | Groneberg DA Doring F Nickolaus M Daniel H Fischer A | 2001 | Neurosci Lett2001,304,3: | 1 |
| 17 | Low-molecular-weight fucoidan enhances the proangiogenic phenotype of endothelial progenitor cells显示文摘 | Faouzia Zemani Danielle Benisvy Isabelle Galy-Fauroux Anna Lokajczyk Sylvia Colliec-Jouault Georges Uzan Anne Marie Fischer Catherine Boisson-Vidal | 2005 | Biochemical Pharmacology2005,,: | 1 |
| 18 | Intestinal peptide transport: ex vivo uptake studies and localization of peptide carrier PEPT1显示文摘 | Groneberg DA Doring F Eynott PR Fischer A Daniel H | 2001 | Am J Physiol Gastrointest Liver Physiol2001,281,3: | 1 |
| 19 | Evaluation of ultrasound velocity measurements for estimating protease activities using casein as substrate显示文摘 | Karin Born Anja Manns Kristina Dzeyk Sabine Lutz-Wahl Daniel Gau Lutz Fischer | 2010 | Biotechnology Letters2010,,2: | 1 |
| 20 | In vivo fracture resistance of implant-supported all-ceramic restorations显示文摘 | Murat Yildirim Horst Fischer Rudolf Marx Daniel Edelhoff | 2003 | The Journal of Prosthetic Dentistry2003,,4: | 1 |