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| 1 | 甲硝唑棒在深牙周袋病损治疗中的作用显示文摘目的 :评价牙康 (甲硝唑棒 )治疗深牙周袋的作用。方法 :牙康 +刮治治疗 7名牙周炎患者的 7个深牙周袋位点 ,单纯刮治另 7个位点为对照。治疗后 7天、2 8天观察龈下微生物变化及临床疗效。结果 :牙康治疗后龈下总细菌数及能动菌、梭形杆菌、螺旋体百分比显著降低 ,7天时显著低于对照 ,配合刮治 2 8天时探深显著低于治疗前 ;而单纯刮治后探深无显著降低。结论 :牙康 +刮治治疗深牙周袋 ,能快而有效地抑制龈下致病微生物 ,临床效果更佳。 | 欧阳翔英 Andrea Mombelli Niklaus Lang | 2001 | 口腔医学纵横2001，17，3： | 18 |
| 2 | 应用BioMod集成多种模型研究物种的空间分布——以铁杉在中国的潜在分布为例显示文摘新型统计方法和多源、多尺度空间信息数据的产生促进了物种空间分布模型的快速发展。不同的物种空间分布模型在生态学理论的运用以及前提假设上存在差异。选用不同的模型方法和输入数据会带来预测结果的不确定性。对比并集成多个物种空间分布模型,同时利用多组输入数据可降低预测的不确定性,提高物种分布模拟的精度。本文以中国特有种铁杉(Tsuga chinensis)为例,运用基于R语言开发的BioMod软件包对比9个物种空间分布模型对铁杉的模拟效果。最后以曲线下面积(ROC)为权重集成9个模型的模拟结果,产生和筛选最佳的铁杉潜在空间分布图。研究发现随机森林模型(RF)的模拟效果最好,其次是多元适应回归样条函数模型(MARS)和广义相加模型(GAM),模拟效果最差的是表面分布区分室模型(SRE)。模型集成结果显示,最适宜铁杉分布的区域集中在中国的西南及四川盆地周围,其次零星分散于华南和台湾部分地区。这一结果与前人对铁杉自然分布的描述和研究结果较为吻合。研究进一步表明,通过模型的集成能有效地降低由于单个模型所带来的模拟结果不确定性,从而提高模拟的精度和效果。 | 毕迎凤 许建初 李巧宏 Antoine Guisan Wilfried Thuiller Niklaus E.Zimmermann 杨永平 杨雪飞 | 2013 | 植物分类与资源学报2013，35，5： | 16 |
| 3 | Manufacture and characterization of graphene membranes with suspended silicon proof masses for MEMS and NEMS applications显示文摘Graphene’s unparalleled strength,chemical stability,ultimate surface-to-volume ratio and excellent electronic properties make it an ideal candidate as a material for membranes in micro-and nanoelectromechanical systems(MEMS and NEMS).However,the integration of graphene into MEMS or NEMS devices and suspended structures such as proof masses on graphene membranes raises several technological challenges,including collapse and rupture of the graphene.We have developed a robust route for realizing membranes made of double-layer CVD graphene and suspending large silicon proof masses on membranes with high yields.We have demonstrated the manufacture of square graphene membranes with side lengths from 7µm to 110µm,and suspended proof masses consisting of solid silicon cubes that are from 5µm×5µm×16.4µm to 100µm×100µm×16.4µm in size.Our approach is compatible with wafer-scale MEMS and semiconductor manufacturing technologies,and the manufacturing yields of the graphene membranes with suspended proof masses were>90%,with>70%of the graphene membranes having>90%graphene area without visible defects.The measured resonance frequencies of the realized structures ranged from tens to hundreds of kHz,with quality factors ranging from 63 to 148.The graphene membranes with suspended proof masses were extremely robust,and were able to withstand indentation forces from an atomic force microscope(AFM)tip of up to~7000nN.The proposed approach for the reliable and large-scale manufacture of graphene membranes with suspended proof masses will enable the development and study of innovative NEMS devices with new functionalities and improved performances. | Xuge Fan Anderson D.Smith Fredrik Forsberg Stefan Wagner Stephan Schroder Sayedeh Shirin Afyouni Akbari Andreas C.Fischer Luis Guillermo Villanueva Mikael Ostling Max C.Lemme Frank Niklaus | 2020 | Microsystems & Nanoengineering2020，6，1： | 4 |
| 4 | A systematic review of the survival and complication rates of fixed partial dentures (FPDs) after an observation period of at least 5 years显示文摘 | KenTan Bjarni E.Pjetursson Niklaus P.Lang Edwin S.Y.Chan | 2004 | Clinical Oral Implants Research2004，，6： | 2 |
| 5 | Predictive habitat distribution models in ecology显示文摘 | Antoine Guisan Niklaus E. Zimmermann | 2000 | Ecological Modelling2000，，2： | 2 |
| 6 | SPINK1 Is a Susceptibility Gene for Fibrocalculous Pancreatic Diabetes in Subjects from the Indian Subcontinent显示文摘 | Zahid Hassan Viswananthan Mohan Liaquat Ali Rebecca Allotey Khalid Barakat M. Omar Faruque Raj Deepa Michael F. McDermott Alan E. Jackson Paul Cassell David Curtis Susan V. Gelding Shanti Vijayaravaghan Niklaus Gyr David C. Whitcomb A.K. Azad Khan Graham | 2002 | The American Journal of Human Genetics2002，，4： | 1 |
| 7 | A novel standardized algorithm for evaluating patients with painful total knee arthroplasty using combined single photon emission tomography and conventional computerized tomography显示文摘 | Michael T. Hirschmann Farhad Iranpour Praveen Konala Anna Kerner Helmut Rasch Justin P. Cobb Niklaus F. Friederich | 2010 | Knee Surgery Sports Traumatology Arthroscopy2010，，7： | 1 |
| 8 | Ridge preservation at implants installed immediately after molar extraction. An experimental study in the dog显示文摘 | Giacomo Favero Niklaus P. Lang Enzo Santis Brismayda Garcia Gonzalez Michael T. Schweikert Daniele Botticelli | 2012 | Clin Oral Implants Res2012，，3： | 1 |
| 9 | Resistance and resilience of the forest soi microbiome to logging-associated compaction显示文摘 | MARTIN HARTMANN PASCAL A NIKLAUS STEPHANZIMMERMANN | 2014 | The ISMEJournal2014，8，： | 1 |
| 10 | A long-term field study on biodi- versity × elevated CO2 interactions in Grassland 显示文摘 | Niklaus P Leadley P Schmid B | 2001 | Ecological Mort-o- graphs2001，71，： | 1 |
| 11 | A prospective, randomized‐controlled clinical trial to evaluate bone preservation using implants with different geometry placed into extraction sockets in the maxilla显示文摘 | MarianoSanz DenisCecchinato JorgeFerrus E. BjarniPjetursson Niklaus P.Lang JanLindhe | 2009 | Clinical Oral Implants Research2009，，1： | 1 |
| 12 | A meta -analysis of responses of soil biota to global change显示文摘 | Blankinship J C Niklaus P A Hungate B A | 2011 | Oecologia2011，165，： | 1 |
| 13 | Predictive habitat distribution models in ecology显示文摘 | Antoine G Niklaus E Z | 2000 | Ecological Modelling2000，135，： | 1 |
| 14 | A meta-analysis of responses of soil biota to global change显示文摘 | Blankinship J C Niklaus P A Hungate B A | 2011 | Oecologia2011，165，3： | 1 |
| 15 | Mechanical characterization of a dielectric elastomer microactuator with Non-implanted electrodes 显示文摘 | ROSSET S NIKLAUS M DUBOIS P | 2008 | Sensors and Actuators A2008，144，： | 1 |
| 16 | The inflammasome mediates UVB-induced activation and secretion of interleukin-1beta by keratinocytes显示文摘 | Feldmeyer L Keller M Niklaus G | 2007 | Curr Biol2007，17，13： | 1 |
| 17 | Predictive habitat distribution models in ecology显示文摘 | Antoine Guisan Niklaus E Zimmenrmann | 2000 | Ecological Modeling2000，135，： | 1 |
| 18 | A meta-analysis of re- sponses of soil biota to global change 显示文摘 | Blankinship J C Niklaus P A Hungate B A | 2011 | Oecologia2011，165，3： | 1 |
| 19 | Integrated silicon ohotonic MEMS显示文摘Silicon photonics has emerged as a mature technology that is expected to play a key role in critical emerging applications,including very high data rate optical communications,distance sensing for autonomous vehicles,photonic-accelerated computing,and quantum information processing.The success of silicon photonics has been enabled by the unique combination of performance,high yield,and high-volume capacity that can only be achieved by standardizing manufacturing technology.Today,standardized silicon photonics technology platforms implemented by foundries provide access to optimized library components,including low-loss optical routing,fast modulation,continuous tuning,high-speed germanium photodiodes,and high-effciency optical and electrical interfaces.However,silicon's relatively weak electro-optic effects result in modulators with a significant footprint and thermo-optic tuning devices that require high power consumption,which are substantial impediments for very large-scale integration in silicon photonics.Microelectromechanical systems(MEMS)technology can enhance silicon photonics with building blocks that are compact,low-loss,broadband,fast and require very low power consumption.Here,we introduce a silicon photonic MEMS platform consisting of high-performance nano-opto-electromechanical devices fully integrated alongside standard silicon photonics foundry components,with wafer-level sealing for long-term reliability,flip-chip bonding to redistribution interposers,and fibre-array attachment for high port count optical and electrical interfacing.Our experimental demonstration of fundamental silicon photonic MEMS circuit elements,including power couplers,phase shifters and wavelength-division multiplexing devices using standardized technology lifts previous impediments to enable scaling to very large photonic integrated circuits for applications in telecommunications,neuromorphic computing,sensing,programmable photonics,and quantum computing. | Niels Quack Alain Yuji Takabayashi Hamed Sttari Pieirre Edinger Gaehun Jo Simon JBleker Carlos Errando-Herranz Kristinn BGylfason Frank Niklaus Umar Khan Peter Verheyen Arun Kumar Malik Jun Su Lee Moises Jezzini Padraic Morrissey Cleitus Antony Peter O'Brien Wim Bogaertso | 2023 | Microsystems & Nanoengineering2023，9，2： | 1 |
| 20 | Long-term CO2 enrichment stimulates N mineralization and enzyme activities in ealeareous grassland显示文摘 | Ebersberger D Niklaus P A Kandeler E | 2003 | Soil Biology and Biochemistry2003，5，： | 1 |
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