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| 1 | 洋葱伯克霍尔德菌对29种抗生素的耐药性分析显示文摘目的 了解洋葱伯克霍尔德菌的耐药特征。方法 用微量稀释法测定洋葱伯克霍尔德菌对 2 9种抗生素的MIC值。结果 2 9种抗生素敏感性测试结果显示 β-内酰胺酶抗生素中青霉素类抗生素哌拉西林、哌拉西林 /他唑巴坦敏感性分别为 82 .2 %和 89.7%;10种头孢类抗生素中的头孢他啶和头孢布烯的敏感性在 85 %左右 ,头孢曲松和头孢克洛为 5 0 %左右 ,其余均 <5 0 %;被测试的两种碳青酶烯类抗生素亚胺培南的敏感性只有7.7%,美罗培南敏感性为 87.2 %;4种氨基糖苷类抗生素敏感率均为 2 .6 %;6种喹诺酮类抗生素除萘啶酸为5 6 .4 %,其他均 <2 5 %;氯霉素的敏感性为 15 .4 %;哌拉西林、哌拉西林 /他唑巴坦、头孢他啶、头孢布烯、美罗培南和甲氧苄啶对洋葱伯克霍尔德菌有较高的活性。结论 洋葱伯克霍尔德菌是一种多重耐药菌 ,体外药敏结果哌拉西林、哌拉西林 /他唑巴坦、头孢他啶、头孢布烯、美罗培南和甲氧苄啶可作为由洋葱伯克霍尔德菌引起感染的治疗药物。 | 罗燕萍 张军民 刘丽 崔岩 杨继勇 Augustine F Cheng | 2002 | 中华医院感染学杂志2002，12，10： | 57 |
| 2 | Acute esophageal variceal bleeding:Current strategies and new perspectives显示文摘Management of acute variceal bleeding has greatly improved over recent years. Available data indicates that general management of the bleeding cirrhotic patient by an experienced multidisciplinary team plays a major role in the f inal outcome of this complication. It is currently recommended to combine pharmacological and endoscopic therapies for the initial treatment of the acute bleeding. Vasoactive drugs (preferable somatostatin or terlipressin) should be started as soon as a variceal bleeding is suspected (ideally during transfer to hospital) and maintained afterwards for 2-5 d. After stabilizing the patient with cautious fluid and blood support, an emergency diagnostic endoscopy should be done and, as soon as a skilled endoscopist is available, an endoscopic variceal treatment (ligation as f irst choice, sclerotherapy if endoscopic variceal ligation not feasible) should be performed. Antibiotic prophylaxis must be regarded as an integral part of the treatment of acute variceal bleeding and should be started at admission and maintained for at least 7 d. In case of failure to control the acute bleeding, rescue therapies should be immediately started. Shunt therapies (especially tran sjugular intrahepatic portosystemic shunt) are very effective at controlling treatment failures after an acute variceal bleeding. Therapeutic developments and increasing knowledge in the prognosis of this complication may allow optimization of the management strategy by adapting the different treatments to the expected risk of complications for each patient in the near future. Theoretically, this approach would allow the initiation of early aggressive treatments in high-risk patients and spare low-risk individuals unnecessary proce dures. Current research efforts will hopefully clarify this hypothesis and help to further improve the outcomes of the severe complication of cirrhosis. | Salvador Augustin Antonio González Joan Genescà | 2010 | World Journal of Hepatology2010，2，7： | 44 |
| 3 | Transjugular intrahepatic portosystemic shunt in cirrhosis: An exhaustive critical update显示文摘More than five decades after it was originally conceptualized as rescue therapy for patients with intractable variceal bleeding,the transjugular intrahepatic portosystemic shunt(TIPS)procedure continues to remain a focus of intense clinical and biomedical research.By the impressive reduction in portal pressure achieved by this intervention,coupled with its minimally invasive nature,TIPS has gained increasing acceptance in the treatment of complications of portal hypertension.The early years of TIPS were plagued by poor long-term patency of the stents and increased incidence of hepatic encephalopathy.Moreover,the diversion of portal flow after placement of TIPS often resulted in derangement of hepatic functions,which was occasionally severe.While the incidence of shunt dysfunction has markedly reduced with the advent of covered stents,hepatic encephalopathy and instances of early liver failure continue to remain a significant issue after TIPS.It has emerged over the years that careful selection of patients and diligent post-procedural care is of paramount importance to optimize the outcome after TIPS.The past twenty years have seen multiple studies redefining the role of TIPS in the management of variceal bleeding and refractory ascites while exploring its application in other complications of cirrhosis like hepatic hydrothorax,portal hypertensive gastropathy,ectopic varices,hepatorenal and hepatopulmonary syndromes,non-tumoral portal vein thrombosis and chylous ascites.It has also been utilized to good effect before extrahepatic abdominal surgery to reduce perioperative morbidity and mortality.The current article aims to review the updated literature on the status of TIPS in the management of patients with liver cirrhosis. | Sasidharan Rajesh Tom George Cyriac Abby Philips Rizwan Ahamed Sandeep Kumbar Narain Mohan Meera Mohanan Philip Augustine | 2020 | World Journal of Gastroenterology2020，26，37： | 26 |
| 4 | Diagnosis of ectopic pancreas by endoscopic ultrasound with fine-needle aspiration显示文摘AIM:To study the clinical,endoscopic,sonographic,and cytologic features of ectopic pancreas(EP).METHODS:This was a retrospective study performedat an academic referral center including two hospitals.Institutional review board approval was obtained.Patients referred to the University Hospital or Denver Health Medical Center Gastrointestinal Endoscopy Lab for gastroduodenal subepithelial lesions(SEL)with a final diagnosis of EP between January 2009and December 2013 were identified.Patients in this group were selected for the study if they underwent endoscopic ultrasound(EUS)with fine-needle aspiration(FNA)or deep biopsy.A review of the medical record was performed specifically to review the following information:presenting symptoms,endoscopic and EUS findings,computed tomography or magnetic resonance imaging findings,pathology results,procedure-related adverse events,and subsequent treatments after EUSFNA.EUS with FNA or deep submucosal biopsy was performed in all patients on an outpatient basais by one of two physicians(Attwell A,Fukami N).Review of all subsequent clinic notes and operative reports was performed in order to determine follow-up and final diagnoses.RESULTS:Between July 2009 and December 2013,10patients[3 males,7 females,median age 52(26-64)years]underwent EUS for a gastroduodenal SEL and were diagnosed with EP.One patient was symptomatic.Six(60%)lesions were in the antrum,3(30%)in the body,and 1(10%)in the duodenum.A mucosal dimple was noted in 6(60%).Mean lesion size was 17(8-25)mm.Gastrointestinal wall involvement:muscularis mucosae,10%;submucosa,70%;muscularis propria,60%;and serosa,10%.Nine(90%)lesions were hypoechoic and 5(50%)were homogenous.A duct was seen in 5(50%).FNA was attempted in 9(90%)and successful in 8(80%)patients after 4(2-6)passes.Cytology showed acini or ducts in 7 of 8(88%).Superficial biopsies in 7 patients(70%)showed normal gastric mucosa.Deep endoscopic biopsies were taken in 2 patients and diagnostic in one.One patient(10%)developed pancreatitis after EUS-FNA.Two patients(20%)underwent surgery to relieve symptoms or confirm the diagnosis.The main limitation of the study was the fact that it was retrospective and performed at a single medical center.CONCLUSION:EUS features of EP include antral location,mucosal dimple,location in layers 3-4,and lesional duct,and FNA or biopsy is accurate and effective. | Augustin Attwell Sharon Sams Norio Fukami | 2015 | World Journal of Gastroenterology2015，21，8： | 22 |
| 5 | 香根草根系固土拉力的原位测定显示文摘应用锚杆拉力计和项目组自行设计改进的剪切箱,原位测定了不同深度(10 cm,20 cm)分蘖期香根草根系固土、单根拉力。结果表明,在给香根草施加载荷初期,根系都会发生弹性形变,荷载与位移都按比例增加,呈现一定的线性关系。当载荷超过根系抗拉极限后,随着拉力的继续增加,根系发生塑性形变,载荷与位移关系逐渐偏离直线,反映出非线性弹性特征,测定的土体样方与土体分离。但与裸土样方相比,在施加同样载荷的情况下,有根样方位移明显要小于无根样方,说明香根草具有一定的固土能力,并且根系入土越深,植物固土能力越强。 | 王斌 范茂攀 郑毅 Michael Augustin FULLEN 李永梅 | 2012 | 云南农业大学学报(自然科学版)2012，27，2： | 9 |
| 6 | 在人工接种和自然感虫情况下美洲黑杨后代对桑天牛抗性的研究显示文摘Two Populus deltoides clones ( P.deltoides Bartr.cl.‘55/65’ and P.deltoides Bartr.cl.‘2KEN8’)with high resistance to Anoplophora glabripennis (Resistant rate are 96.16%,97.37%,respectively) were used as parents and crossed by artificial controlled pollination,37 among of which F 1 progenies were planted in Shuyang,Jiangsu province and tested for insect resistance with the borer Apriona germari Hope.Under artificial inoculation and natural infestation with Apriona germari Hope,significant variations of oviposition and larval development were observed between progenies.Both artificial inoculation and natural infestation alow the characterization of plant resistance to insect,although insect behavioral responses sometimes differ between free choice (natural infestation) and no choice experiment (inoculation). | 胡建军 韩一凡 尹伟伦 Sylvie Augustin Marc Villar | 2002 | 林业科学2002，38，1： | 8 |
| 7 | Electrospun poly(vinylidene fluoride-trifluoroethylene)/ zinc oxide nanocomposite tissue engineering scaffolds with enhanced cell adhesion and blood vessel formation显示文摘响应机械紧张产生电的信号的压电的材料能在设计刺激房间增长的织物被使用。Poly (vinylidene fluoride-trifluoroethylene )(P (VDF-TrFE )) ,压电的聚合物,广泛地在 biomaterial 应用被使用。我们假设了进 P (VDF-TrFE ) 矩阵的 nanoparticles 能支持的锌氧化物(ZnO ) 的那加入房间的粘附,移植,和增长,以及血容器形成(angiogenesis ) 。在这研究,我们制作了并且包括地描绘了新奇 electrospun P (VDF-TrFE )/ZnO nanocomposite 织物设计支架。我们由扫描电子显微镜学分析了聚合矩阵的词法特征,并且利用了红外线的光谱学, X 光检查衍射,和检验的微分扫描热量测定由于 nanoparticles 的增加在共聚物的水晶的阶段改变的 Fourier 变换。我们不检测了,显示 P (VDF-TrFE )/ZnO nanocomposite 脚手架对设计应用的织物合适或关于在 vitro, biocompatibility,和 cytotoxicity 的血相容性的 biomaterials 的最小的不利效果。有趣地,人的间充质的干细胞(hMSCs ) 和在 nanocomposite 脚手架上有教养的人的脐的静脉 endothelial 房间与在织物文化盘子或整洁的 P (VDF-TrFE ) 上有教养的房间相比展出了更高的房间生存能力,粘附,和增长脚手架。植入进老鼠与或没有 hMSCs 的 Nanocomposite 脚手架没得到免疫学的回答,由宏观的分析和组织学估计了。重要地, nanocomposite 脚手架支持了 angiogenesis,它在脚手架被增加与 hMSCs 预先播种。总的来说,我们的结果在织物工程为使用加亮这些新奇 P (VDF-TrFE )/ZnO nanocomposites 的潜力,由于他们支持房间粘附和 angiogenesis 的 biocompatibility 和能力。 | Robin Augustine Pan Dan Alejandro Sosnik Nandakumar Kalarikkal Nguyen Tran Brice Vincent Sabu Thomas Patrick Menu Didier Rouxel | 2017 | Nano Research2017，10，10： | 8 |
| 8 | 玉米根系原位固土力学特性研究显示文摘通过采用自制的剪切箱和锚杆拉力计对玉米(云瑞8号,Zea mays.L)根系在10 cm和20 cm两个深度上和空地样方的固土能力进行了原位测定比较。结果表明,施加相同载荷时,两种深度空地样方位移大于有根玉米样方;20 cm深度样方位移为4个样方中最小。作物扎根越深,达到剪切分离样方特征点所需的载荷越大。10cm玉米样方屈服拉力点载荷为2.7 kN,抗拉极限点载荷为2.9 kN;20 cm玉米样方屈服拉力点载荷为3.6 kN,抗拉极限点载荷为3.61 kN;10 cm空地样方两点载荷分别为2.3 kN和2.5 kN;20 cm深度空地样方载荷分别为3.1 kN和3.4 kN。该方法可直接量化测定玉米根系固土能力,为农业水土保持提供了有效研究手段。 | 郑朝元 范茂攀 郑毅 Michael Augustin FULLEN 李永梅 Mudhu SUBEDI | 2010 | 云南农业大学学报(自然科学版)2010，25，4： | 7 |
| 9 | COHERENT, REGULAR AND SIMPLE SYSTEMS IN ZERO DECOMPOSITIONS OF PARTIAL DIFFERENTIAL SYSTEMS显示文摘This paper studies triangular differential systems arising from various decompositions of partial differential polynomial systems. In theoretical aspects, we emphasizeon translating differential problems into purely algebraic ones. Rosenfeld’s lemma is extended to a more general setting; relations between passivity and coherence are clarified;regular systems and simple systems are generalized and proposed, respectively. In algorithmic aspects, we review the Ritt-Wu and Seidenberg algorithms, and outline a methodfor decomposing a differential polynomial system into simple ones. Some applications arealso discussed. | LI Ziming(Institute Of Algorithms and Scientific Computing, German National Research Centerfor Information Technology, D-52754 Sankt Augustin, Germany)WANG Dongming(LEIBNIZ-IMAG, 46, Avenue Felix Viallet,38031 Grenoble Cedex, France) | 1999 | Systems Science and Mathematical Sciences1999，12，S1： | 7 |
| 10 | Gardner's syndrome:Genetic testing and colonoscopy are indicated in adolescents and young adults with cranial osteomas:A case report显示文摘We present a case of a 25-year-old female with diagnosed familial adenomatous polyposis and elevated carcinoembryonic antigen with negative family history. The suspicion of Gardner's syndrome was raised because extirpation of an osteoma of the left temporo-occipital region was made 10 years ago. Restorative procto-colectomy and ileal pouch anal anastomosis was made but histology delineated adenocarcinoma of the rectum (Dukes C stage). We conclude that cranial osteomas often precede gastrointestinal manifestations of familial adenomatous polyposis or Gardner's syndrome and such patients should be evaluated with genetic testing followed by colonoscopy if results are positive to prevent the development of colorectal carcinoma. If the diagnosis is positive all family members should be evaluated for familial adenomatous polyposis. | Dubravko Smud Goran Augustin Tihomir Kekez Emil Kinda Mate Majerovic Zeljko Jelincic | 2007 | World Journal of Gastroenterology2007，13，28： | 7 |
| 11 | 油菜根系固土拉力的原位测定研究显示文摘应用锚杆拉力计和自行设计的剪切箱对不同根系密度的油菜根系固土能力在10 cm深度进行了原位测定。结果表明,当施加载荷达到3.5 kN时,生长有油菜的土壤样方1(根系密度为1.11 kg/m3)位移为38.0mm,生长有油菜的土壤样方2(根系密度为0.57 kg/m3)位移为46.0 mm,而裸土样方位移为49.7 mm。土壤样方内根系密度越大,达到土壤样方与土体分离的特征点所需要施加的载荷就越大。土壤样方1的屈服拉力点为3.5 kN,抗拉极限点为4.0 kN;而土壤样方2的屈服拉力点为3.1 kN,抗拉极限点为3.5 kN。该测定方法可以在水土保持上作为评价不同作物(植物)固土能力的有效参考手段。 | 毛妍婷 郑毅 Michael Augustin FULLEN 李永梅 Mudhu SUBEDI | 2008 | 云南农业大学学报(自然科学版)2008，23，6： | 6 |
| 12 | 内皮Notch信号的抑制阻碍脂肪酸转运并导致成年心脏的代谢和血管重塑显示文摘营养成分在被肌肉细胞代谢利用之前通过内皮细胞转运。然而,对于内皮运输过程的调节知之甚少。Notch信号传导是发育过程中代谢和血管生成的关键调控因子。在该研究中,Jabs等研究了成年小鼠内皮Notch信号的遗传和药理学调控如何影响内皮脂肪酸转运、心脏血管生成和心脏功能。 | 刘青 叶鹏 Jabs M Rose AJ Lehmann LH Taylor J Moll I Sijmonsma TP Herberich SE Sauer SW Poschet G Federico G Mogler C Weis EM Augustin HG Yan M Gretz N Schmid RM Adams RH Gr9ne HJ Hell R Okun JG Backs J Nawroth PP Herzig S Fischer A | 2018 | 中华高血压杂志2018，26，3： | 6 |
| 13 | Suture granuloma of the abdominal wall with intra-abdominal extension 12 years after open appendectomy显示文摘Most complications after appendectomy occur within ten days; however, we report the unusual case of a suture granuloma 12 years after open appendectomy. The afebrile 75-year-old woman presented with a slightly painful palpable mass in the right lower abdomen. There was no nausea or vomiting and bowel movements were normal. She lost 10 kg during the 3 mo before presentation. The patient had undergone an appendectomy 12 years previously. Physical examination revealed a tender mass, 10 cm in diameter, under the appendectomy scar. The preoperative laboratory findings, tumor markers and plain abdominal radiographs were normal. Multi-slice computed tomography scanning showed an inhomo-genous abdominal mass with minimal vascularization in the right lower abdomen 8.6cm×8cm×9 cm in size which communicated with the abdominal wall. The abdominal wall was thickened, weak and bulging. The abdominal wall mass did not communicate with the cecum or the ascending colon. Complete excision of the abdominal wall mass was performed via median laparotomy. Histopathological examination revealed a granuloma with a central abscess. This case report demonstrates that a preoperative diagnosis of abdominal wall mass after open appendectomy warrants the use of a wide spectrum of diagnostic modalities and consequently different treatment options. | Goran Augustin Dragan Korolija Mate Skegro Jasminka Jakic-Razumovic | 2009 | World Journal of Gastroenterology2009，15，32： | 5 |
| 14 | Application of Ordinary Kriging in Mapping Soil Organic Carbon in Zambia显示文摘The quantification of the pattern and spatial distribution of soil organic carbon(SOC) is fundamental to understand many ecosystem processes. This study aimed to apply ordinary kriging(OK) to model the spatial distribution of SOC in a selected part of Zambia. A total of 100 soil samples were collected from the study area and analyzed for SOC by determining soil oxidizable carbon using the Walkley-Black method. An automated fitting procedure was followed when modeling the spatial structure of the SOC data with the exponential semivariogram. The results indicated that the short range spatial dependence of SOC was strong with a nugget close to zero. The spatial autocorrelation was high to medium with a nugget to sill ratio of 0.25. The root mean square error of the predictions was 0.64, which represented 58.18% of the mean observed data for SOC. It can be concluded that the generated map could serve as a proxy for SOC in the region where evidence of spatial structure and quantitative estimates of uncertainty are reported.Therefore, the maps produced can be used as guides for various uses including optimization of soil sampling. | Lydia Mumbi CHABALA Augustine MULOLWA Obed LUNGU | 2017 | Pedosphere2017，27，2： | 5 |
| 15 | Rectal cancer and Fournier's gangrene- current knowledge and therapeutic options显示文摘Fournier's gangrene(FG) is a rapid progressive bacterial infection that involves the subcutaneous fascia and part of the deep fascia but spares the muscle in the scrotal,perianal and perineal region. The incidence has increased dramatically,while the reported incidence of rectal cancer-induced FG is unknown but is extremely low. Pathophysiology and clinical presentation of rectal cancer-induced FG per se does not differ from the other causes. Only rectal cancer-specific symptoms before presentation can lead to the diagnosis. The diagnosis of rectal cancer-induced FG should be excluded in every patient with blood on digital rectal examination,when urogenital and dermatological causes are excluded and when fever or sepsis of unknown origin is present with perianal symptomatology. Therapeutic options are more complex than for other forms of FG. First,the causative rectal tumor should be removed. The survival of patients with rectal cancer resection is reported as 100%,while with colostomy it is 80%. The preferred method of rectal resection has not been defined. Second,oncological treatment should be administered but the timing should be adjusted to the resolution of the FG and sometimes for the healing of plastic reconstructive procedures that are commonly needed for the reconstruction of large perineal,scrotal and lower abdominal wall defects. | Tomislav Bruketa Matea Majerovic Goran Augustin | 2015 | World Journal of Gastroenterology2015，21，30： | 5 |
| 16 | Colonic duplication in an adult who presented with chronic constipation attributed to hypothyroidism显示文摘Gastrointestinal duplications are an uncommon congenital abnormality that manifest before the age of two in 80% of cases. Ileal duplication is the most common while colonic duplication,either cystic or tubular,occurs in 10%-15% of cases and remains asymptomatic and undiagnosed in most cases. Mostly occurring in pediatric patients,colonic duplication is encountered in adults in only a few cases. The most common clinical manifestations are abdominal pain and intestinal obstruction. Rarely,duplications present with signs of acute abdomen or acute bleeding. This study reports a case of colonic duplication in an adult who presented with chronic constipation. Complete diagnostic workup was made on several occasions during the previous eight year period,but no pathology was found and chronic constipation was attributed to hypothyroidism caused by long standing Hashimoto thyroiditis. Multislice CT,performed because of abdominal distension,defined colonic pathology but the definite diagnosis of duplication of the transversal colon was made at operation. The cystic duplication and the adjacent part of the ascending and transversal colon were excised en-block. This study implies that colonic duplication,though uncommon,should be included in the differential diagnosis of chronic constipation even when precipitating factors for constipation,such as hypothyroidism are present. | Tihomir Kekez Goran Augustin Irena Hrstic Dubravko Smud Mate Majerovic Zeljko Jelincic Emil Kinda | 2008 | World Journal of Gastroenterology2008，14，4： | 5 |
| 17 | Diagnostic challenge of lipomatous uterine tumors in three patients显示文摘Lipomatous uterine tumors are uncommon benign neoplasms, with incidence ranging from 0.03% to 0.2%. They can generally be subdivided into two types: pure or mixed lipomas. A third group of malignant neoplasm has been proposed, which is liposarcoma; however, this is very rare. In this article, we report three patients having lipomatous uterine tumors, including one uterine lipoma and two uterine lipoleiomyomas. All our patients are postmenopausal women, which is the typical presenting age group. They did not have any symptoms and the tumors were only found incidentally on imaging. However, in some patients, symptoms may uncommonly occur. If symptoms occur, these are similar to those of leiomyoma. We illustrate the imaging features of the tumors in our patients with ultrasound, computed tomography (CT) scan and magnetic resonance imaging (MRI). The tumor typically appears as a well-defined homogenously hyperechoic lesion on ultrasound. It shows fat density on CT scan and signal intensity of fat on MRI. MRI is the modality of choice because of its multiplanar capability and its ability to demonstrate fat component of the lesion, as illustrated in our cases. We also discuss the importance of differentiating lipomatous uterine tumors from other lesions, especially ovarian teratoma which requires surgical intervention. Despite the rarity and the common asymptomatic nature of the tumors, we believe that this series of three cases demonstrates a review of a rare tumor which provides important knowledge for patient management. | Chi-Yeung Chu Yip-Kan Tang Tin-Sang Augustine Chan Yu-Hon Wan Kai-Hung Fung | 2012 | World Journal of Radiology2012，4，2： | 4 |
| 18 | Slope Processes, Mass Movement and Soil Erosion: A Review显示文摘Soil erosion and land degradation are global problems and pose major issues in many countries.Both soil erosion and mass movement are two forms of land degradation and humans play important roles in these geomorphological processes.This paper reviews slope processes associated with mass movement and soil erosion and contributory factors,including physical and human agents.Acting together,these cause diverse geomorphological features.Slope processes are illustrated by reference to case studies from Brazil and UK.The causes and impacts of erosion are discussed,along with appropriate remedial bioengineering methods and the potential of the measures to prevent these types of environmental degradation.Although there are several agents of erosion,water is the most important one.Cultivation can promote soil erosion,due to ploughing and harvesting,which moves soil down slopes.Soil erosion and mass movement data would inform the viability of soil conservation practices.Integrated management of drainage basins offers a promising way forward for effective soil conservation and soil remedial bioengineering in Brazil and UK. | Antonio Jos Teixeira GUERRA Michael Augustine FULLEN Maria do Carmo Oliveira JORGE Joss Fernando Rodrigues BEZERRA Mohamed S. SHOKR | 2017 | Pedosphere2017，27，1： | 4 |
| 19 | The composition and diversity of natural regeneration of tree species in gaps under different intensities of forest disturbance显示文摘The positive ecological interaction between gap formation and natural regeneration has been examined but little research has been carried out on the effects of gaps on natural regeneration in forests under different intensities of disturbance.This study evaluates the composition,diversity,regeneration density and abundance of natural regeneration of tree species in gaps in undisturbed,intermittently disturbed,and disturbed forest sites.Bia Tano Forest Reserve in Ghana was the study area and three gaps each were selected in the three forest site categories.Ten circular subsampling areas of 1 m2 were delineated at 2 m spacing along north,south,east,and west transects within individual gaps.Data on natural regeneration<350 cm height were gathered.The results show that the intensity of disturbance was disproportional to gap size.Species diversity differed significantly between undisturbed and disturbed sites and,also between intermittently disturbed and disturbed sites for Simpson’s(1-D),Equitability(J),and Berger-Parker(B-P)indices.However,there was no significant difference among forest sites for Shannon diversity(H)and Margalef richness(MI)indices.Tree species composition on the sites differed.Regeneration density on the disturbed site was significantly higher than on the two other sites.Greater abundance and density of shade-dependent species on all sites identified them as opportunistic replacements of gap-dependent pioneers.Pioneer species giving way to shade tolerant species is a natural process,thus make them worst variant in gap regeneration. | Maame Esi Hammond Radek Pokorný Daniel Okae-Anti Augustine Gyedu Irene Otwuwa Obeng | 2021 | Journal of Forestry Research2021，32，5： | 3 |
| 20 | Antihyperglycemic effects of the methanol leaf extract of Diaphananthe bidens in normoglycemic and streptozotocin—induced hyperglycemic rats显示文摘Objective:To evaluate the methanol leaf extract of Diaphonathe bidem(D.bidenx)(AFZEL EX SW) SCHLTR for antihyperglycemic activity in order to confirm it antidiabetic potential.Methods: D.bidenx was extracted by cold maceration for 48 h and concentrated in vacuo to yield D.bidenx extract(DBE).Hyperglycemia was induced by intraperitoneal administration of slreplozotocin (75 mg/kg).Oral glucose tolerance test was done with 2 g/kg glucose load in normal rats.DBE (150.300 and 600 mg/kg) was administered orally,while tolbutamide(100 mg/kg.p.o.) was used as the standard reference drug.Blood glucose levels determined using ACCUCHEK glucose autoanalyzer. The acute toxicity and phytochemical studies were also carried out.Results:DBF. (600 mg/kg) and tolbutamide(100 mg/kg) significantly(P<0.05,0.005) reduced blood glucose levels of rats between 120 and 480 nun post administration in normal rats.In the streptozotoeininduced hyperglycemic rats,DBE(150.300.600 mg/kg) caused significant(P<0.001)dose- and time- dependent reduction in the blood glucose levels by 1.7%.22.8%and 43.4%,respectively at 480 min compared to the negative control group.DBE(600 mg/kg) reduced the blood glucose level of rats by 1.2%in the oral glucose tolerance test when compared with the normal saline treated group.The acute toxicity test showed that DBE was safe at the doses used and the phytochemical screening revealed the presence of saponins,steroids,tannins and terpernoids.Conclusions:D. bidens extract possess antihyperglycemic activity which may be mediated through pancreatic and extra-pancreatic pathways,thereby justifying it folkloric use. | Anaga Aruh Ottah Onuoha Augustine Igboeli Okechukwu Obiora Ezeja Maxwell | 2012 | Asian Pacific Journal of Tropical Medicine2012，5，3： | 3 |
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