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| 1 | 基质诱导的自体软骨细胞移植术修复膝关节软骨缺损10例术后2年的随访显示文摘目的应用基质诱导的自体软骨细胞移植技术(MACI,Genzyme,America)对膝关节软骨损伤的患者进行治疗,通过对患者进行术后2年的随访分析,评价MACI治疗的安全性和有效性。方法从2004年至2008年11月,对10例患者实施MACI手术。患者平均年龄34.9岁(14~57岁),缺损的平均面积(3.69±2.62)cm2/处(0.4~8cm2,n=20)。MACI技术是从患者非负重区取自体关节软骨,进行体外消化并分离出软骨细胞,培养扩增后接种在Ⅰ/Ⅲ型双层胶原膜上。移植前按缺损的部位修剪成相应形状,用生物蛋白胶将胶原膜粘贴在关节软骨缺损处。分别于术前1周、术后3个月、6个月、1年和2年使用KOOS评分问卷进行临床康复效果的评估并进行术后核磁共振的检测(MRI)。此外,术后对2例患者进行了3次关节镜检查和2次组织学检测。结果 10例患者术后均未发生并发症及与手术相关的不良事件。患者术后3个月KOOS评分显示疼痛明显改善(P<0.05);术后6个月KOOS评分显示:疼痛、症状、日常生活、运动及娱乐和生活质量5项均明显升高,5项评分间有统计学差异(P<0.05)。术后1年和2年患者的情况得到了持续的改善(P<0.05)。患者术后3个月的MRI显示软骨缺损部位得到大部分填充和修复;6个月移植软骨基本与周围软骨完全整合;1年后修复组织呈等信号,软骨下骨髓水肿消失;2年后大部分患者软骨修复组织信号与周围组织信号强度一致,软骨下骨无骨髓水肿。术后15个月和2年的组织学检查显示新生的软骨组织以透明软骨为主。MACI手术一般都能在2h内完成,术中出血量小于100ml。结论 MACI技术是修复关节软骨缺损安全、可靠和有效的治疗措施,具有操作简单、手术时间短和术中出血量少等特点。 | 张仲文 侯世科 杨造成 唐子滨 钟心 杨传铎 白建鹏 郑铭豪 David Wood | 2010 | 中华关节外科杂志(电子版)2010，4，6： | 14 |
| 2 | Atrial fibrillation: the current epidemic显示文摘 | Carlos A Morillo Amitava Banerjee Pablo Perel David Wood Xavier Jouven | 2017 | Journal of Geriatric Cardiology2017，14，3： | 7 |
| 3 | 基质诱导的自体软骨细胞移植一例显示文摘 | 张仲文 杨造成 侯世科 白建鹏 杨传铎 高春华 匡正达 叶启彬 郑铭豪 David J Wood | 2006 | 中华外科杂志2006，44，4： | 7 |
| 4 | 利用井筒稳定性分析确定砂岩安全钻井液密度窗口显示文摘以伊朗西南部某油田Asmari组砂岩储集层为研究对象,研究其中一口垂直井的井筒稳定性,利用FLAC3D软件,根据钻遇地层地质力学特征建立井筒的有限体积模型,监测井壁岩石塑性状态的形成以确定砂岩层安全钻井液密度的上限值和下限值。评估了岩石强度特性、井筒周围主要地应力和孔隙压力对该井安全钻井液密度窗口的影响,敏感性分析结果表明,井壁岩石内聚力和内摩擦角的减小会导致安全钻井液密度窗口大幅变窄;孔隙压力和最大水平应力与最小水平应力之比的减小则会使安全钻井液密度窗口显著增大。此模型便于量化安全钻井液密度窗口的变化,可作为一种油气井钻井方案设计和监测工具。 | DARVISHPOUR Ayoub SEIFABAD Masoud Cheraghi WOOD David Anthony GHORBANI Hamzeh | 2019 | 石油勘探与开发2019，46，5： | 5 |
| 5 | Characterization of artificial spherical particles for DEM validation studies显示文摘This paper describes a study in which advanced particle-scale characterization was carried out on spherical particles that can be used in experimental tests to validate discrete element method (DEM) simulations. Two types of particle, alkaline and borosilicate glass beads, made from two different materials, were considered. The particle shape, stiffness, contact friction properties and surface roughness were measured. The influences of hardness and roughness on the mechanical response of the particles were carefully considered. Compared to the alkaline beads, the borosilicate beads were more spherical and more uniform in size, and they exhibited mechanical characteristics closer to natural quartz sand. While only two material types were studied, the work has the broader implication as a methodology for selecting particles suitable for use in DEM studies and the key parameters that should be considered in the selection process are highlighted. | Ignazio Cavarretta Catherine O'Sullivan Erdin Ibraim Martin Lings Simon Hamlin David Muir Wood | 2012 | Particuology2012，10，2： | 3 |
| 6 | Transanal rectosigmoid resection via natural orifice translumenal endoscopic surgery (NOTES) with total mesorectal excision in a large human cadaver series显示文摘 | Dana A. Telem Kyung Su Han Min-Chan Kim Ifode Ajari Dae Kyung Sohn Kevin Woods Varun Kapur Mohammad A. Sbeih Silvana Perretta David W. Rattner Patricia Sylla | 2013 | Surgical Endoscopy2013，，1： | 3 |
| 7 | Hepatitis B and C infection and liver disease trends among human immunodeficiency virus-infected individuals显示文摘AIM:To examine trends in and correlates of liver disease and viral hepatitis in an human immunodeficiency virus (HIV)-infected cohort. METHODS:The multi-site adult/adolescent spectrum of HIV-related diseases (ASD) followed 29 490 HIVinfected individuals receiving medical care in 11 U.S. metropolitan areas for an average of 2.4 years,and a total of 69 487 person-years,between 1998 and 2004. ASD collected data on the presentation,treatment,and outcomes of HIV,including liver disease,hepatitis screening,and hepatitis diagnoses. RESULTS:Incident liver disease,chronic hepatitis B virus (HBV),and hepatitis C virus (HCV) were diagnosed in 0.9,1.8,and 4.7 per 100 person-years. HBV and HCV screening increased from fewer than 20% to over 60% during this period of observation (P < 0.001). Deaths occurred in 57% of those diagnosed with liver disease relative to 15% overall (P < 0.001). Overall 10% of deaths occurred among individuals with a diagnosis of liver disease. Despite care guidelines promoting screening and vaccination for HBV and screening for HCV,screening and vaccination were not universally conducted or,if conducted,not documented. CONCLUSION:Due to high rates of incident liver disease,viral hepatitis screening,vaccination,and treatment among HIV-infected individuals should be a priority. | Susan E Buskin Elizabeth A Barash John D Scott David M Aboulafia Robert W Wood | 2011 | World Journal of Gastroenterology2011，17，14： | 2 |
| 8 | 连铸结晶器技术的开发--最新全陶瓷镀层结晶器显示文摘描述了最新全陶瓷镀层结晶器的跟踪实验,实验涉及到铸坯质量和机器操作性能的改善.铜板窄面磨损是连铸机结晶器使用寿命典型的限制性因素.然而,随着CASTCOAT的开发,陶瓷镀层应用于窄面,这已经不再是严重的问题.相反,增加连铸机结晶器使用寿命的限制性因素是宽面的磨损.为了增加使用寿命,结晶器宽面铜板显示了一种在铜板底部的磨损形式.这种磨损形式可以在窄面和宽面之间产生小的'角部缝隙'.在某些情况下,这种'角部缝隙'允许钢液进入,产生飞边缺陷.在结晶器调宽过程中,如果这种飞边存在,那么就存在着宽面刮伤的可能.此外,一些宽面磨损可以影响出结晶器的铸坯形状,从而影响板坯内部质量.为了减少宽面磨损,Corus Process Engineering已测试了各种镀层和镀层系统,包括全镍镀层,分步镀镍镀层,铬镀层,镍铬镀层.但是由于一些问题,在英国这些镀层并没有被采用.因此,决定开发应用于铜板宽面的陶瓷镀层技术.这一开发需要大量的用于升级连铸机设备的投资.同时也需要为镀层实验付出大量的努力.为确保连续镀层厚度的程序被应用.一副镀陶瓷的宽面铜板被安装在Corus Tesside Lackenby(碳钢)双流连铸机上.第二流在采用普通铜板的情况下运行,以直接比较结果.另一副镀陶瓷的宽面铜板被安装在Outokumpu Stainless(Sheffield)单流连铸机上.在跟踪实验中,铜板发生了非常小的磨损,铸坯形状得到很好的保持.和作为对比的铜板相比,镀陶瓷的宽面铜板使用了更长的时间.与无粘结相联系的其他优点有减少宽面的刮伤、减少粘结漏钢警报、改善铸坯的表面质量.宽面镀陶瓷技术计划成为结晶器各个铜板镀层的通用技术.Arcelor和Nucor也同意并计划开展跟踪实验.Corus Process Engineering也开发了CASTCOATⅡ,这是一项改进的陶瓷镀层技术,它更适合于较高的磨损区域,如双流连铸机中间的分隔装置. | Kevin Goode David Jenkinson Brian Stalker Charles Bradley-Smith Kevin Davis Peter Watson John Wood Bryan Allcock | 2004 | 钢铁2004，39，z1： | 2 |
| 9 | 中美医院财务管理的差距显示文摘医院财务管理是一种综合性的管理,涉及到医院的外部环境和医院内部的各种管理,需要借鉴国内外各种先进的管理理论和经验。为此,由本刊与北京卫生经济学会联合主办,北京望海康信科技有限公司和北京华美康医院管理咨询有限公司协办的中美医院财务管理高峰论坛。 | Richard Clarke(嘉宾) Steven Berger(嘉宾) David Wood(嘉宾) 张伟(主持人) 朱万里(整理) 彭海涛(图) | 2006 | 中国医院院长2006，，1： | 2 |
| 10 | Changing grading of soil: effect on critical states显示文摘 | David Muir Wood Kenichi Maeda | 2008 | Acta Geotechnica2008，，1： | 2 |
| 11 | Importance of Low Preoperative Platelet Count in Selecting Patients for Resection of Hepatocellular Carcinoma: A Multi-Institutional Analysis显示文摘 | Shishir K. Maithel Peter J. Kneuertz David A. Kooby Charles R. Scoggins Sharon M. Weber Robert C.G. Martin Kelly M. McMasters Clifford S. Cho Emily R. Winslow William C. Wood Charles A. Staley | 2011 | Journal of the American College of Surgeons2011，，4： | 2 |
| 12 | Projected effectiveness of HIV detection during early infection and rapid ART initiation among MSM and transgender women in Peru: A modeling study显示文摘Background:The Sabes study,a treatment as prevention intervention in Peru,tested the hypothesis that initiating antiretroviral therapy(ART)early in HIV infection when viral load is high,would markedly reduce onward HIV transmission among high-risk men who have sex with men(MSM)and transgender women(TW).We investigated the potential population-level benefits of detection of HIV early after acquisition and rapid initiation of ART.Methods:We designed a transmission dynamic model to simulate the HIV epidemic among MSM and TW in Peru,calibrated to data on HIV prevalence and ART coverage from 2004 to 2011.We assessed the impact of an intervention starting in 2018 in which up to 50%of the new infections were diagnosed within three months of acquisition and initiated on ART within 1 month of diagnosis.We estimated the impact of the intervention over 20 years using the cumulative prevented fraction of new HIV infections compared to scenarios without intervention.Findings:Our model suggests that only 19%of the infected MSM and TW are virally suppressed in 2018 and 35%e40%of the new HIV infections are transmitted from contacts with acutely-infected partners.An intervention reaching 10%of all acutely infected MSM and TW is projected to prevent 13.3%[Uncertainty interval:11.9%e14.3%]of the new infections over 20 years and reduce HIV incidence in 2038 by 24%.Reaching 50%of all acutely infected MSM and TWwill increase the prevalence of viral suppression in 2038 to 59%and prevent 41%of expected infections over 20 years.Reaching 50%of the high-risk MSM and TW in acute phase would reduce HIV incidence in 2038 by 60%and prevent 36%of new infections between 2018 and 2038.Conclusions:Early detection of HIV infections and rapid initiation of ART among MSM is desirable as it would increase the effectiveness of the HIV prevention program in Peru.Targeting high-risk MSM and TW will be highly efficient. | Dobromir Dimitrov Daniel Wood Angela Ulrich David A.Swan Blythe Adamson Javier R.Lama Jorge Sanchez Ann Duerr | 2019 | Infectious Disease Modelling2019，4，1： | 2 |
| 13 | Comparison of Central and Extended Left Pancreatectomy for Lesions of the Pancreatic Neck显示文摘 | Lee M. Ocuin MD Juan M. Sarmiento MD Charles A. Staley MD John R. Galloway MD Colin D. Johnson MD William C. Wood MD David A. Kooby MD | 2008 | Annals of Surgical Oncology2008，，8： | 2 |
| 14 | Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock显示文摘 | Anand Kumar Daniel Roberts Kenneth E. Wood Bruce Light Joseph E. Parrillo Satendra Sharma Robert Suppes Daniel Feinstein Sergio Zanotti Leo Taiberg David Gurka Aseem Kumar Mary Cheang | 2006 | Critical Care Medicine2006，，6： | 2 |
| 15 | 病害防治措施显示文摘美国北卡罗莱纳州立大学农业推广服务部(Agricuetural Extension Service north Caroeina University),每年对该州烟草生产,均发布《烟草资料》(“Tobacco Information”),这一刊物是用以指导烟草生产的技术指南。兹将《1989年烟草资料》(“Tobacco Informetion1989”)中第62~94页的烤烟“病害防治措施”的大部分,摘译出来,供我国从事烤烟病害防治和烟草病害调查的同志们参考。 | Jhomar A. meeton David Potter Keith Wood 陈瑞泰 | 1989 | 中国烟草科学1989，，2： | 2 |
| 16 | Elite swimmers and the D allele of the ACE I/D polymorphism显示文摘 | DAVID WOODS MICHELLE HICKMAN YALDA JAMSHIDI | 2001 | Hum Genet2001，108，： | 1 |
| 17 | Results of tests of etched foil regenerator material 显示文摘 | Matthew P Mitchell David Gedeon Gary Wood | 2007 | Cryocool- ers2007，14，： | 1 |
| 18 | Multidetector Computed Tomography in Transcatheter Aortic Valve Implantation显示文摘 | Jonathon Leipsic Ronen Gurvitch Troy M. LaBounty James K. Min David Wood Mark Johnson Amr M. Ajlan Namal Wijesinghe John G. Webb | 2011 | JACC: Cardiovascular Imaging2011，，4： | 1 |
| 19 | Effect of direct liquid water injection and interdigitated flow field on the performance of proton exchange membrane fuel cells显示文摘 | David L Wood Jung S Yi Trung V Nguyen | 1996 | Electrochimica Acta1996，43，24： | 1 |
| 20 | Ecohydrology and hydroecology:A ' new paradigm显示文摘 | David M Hannah Paul J Wood Jonathan P Sadler | | 0，，： | 1 |
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