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| 1 | An Analysis and Modeling Study of a Sea Fog Event over the Yellow and Bohai Seas显示文摘In this study, a sea fog event which occurred on 27 March 2005 over the Yellow and Bohai Seas was investigated obser- vationally and numerically. Almost all available observational data were used, including satellite imagery of Geostationary Opera- tional Environmental Satellite (GOES)-9, three data sets from station observations at Dandong, Dalian and Qingdao, objectively reanalyzed data of final run analysis (FNL) issued by the National Center for Environmental Prediction (NCEP) and Regional At- mospheric Modeling System (RAMS) results. Synoptic conditions and fog characteristics were analyzed. The fog formed when warm, moist air was advected northwards over the cool water of the Yellow and Bohai Seas, and dissipated when a cold front brought northerly winds and cool, dry air. In order to better understand the fog formation mechanism, a high-resolution RAMS modeling with a 6 km×6 km grid, initialized and validated by FNL data, was designed. A 48 h modeling that started from 12 UTC 26 March 2005 reproduced the main characteristics of this sea fog event. The simulated lower visibility area agreed reasonably well with the sea fog region identified from the satellite imagery. Advection cooling effect seemed to play a significant role in the fog formation. | FU Gang GUO Jingtian Angeline Pendergrass LI Pengyuan | 2008 | Journal of Ocean University of China2008，7，1： | 26 |
| 2 | 皮质类固醇治疗外伤性视神经病变的四天关键时期显示文摘目的:评估静脉注射甲基强的松龙(IVMP)对外伤性视神经病变患者的疗效。
方法:回顾性分析2000-01至2007-06我院收治的16例外伤性视神经病变(TON)患者的临床资料。1g甲基强的松龙分3d静脉应用,然后口服泼尼松龙11d,并逐渐减量。记录从损伤开始到治疗开始的时间。视力变化是本研究结果的主要功能评价指标。在入院时,治疗后1,2,3d;1wk和1mo时,分别记录最佳矫正视力(BCVA)。
结果:共有16例患者纳入本研究,平均年龄为30岁,其中男性14例、女性2例。引起TON的主要原因有摩托车事故(占69%),打架斗殴(占19%)和体育运动(占12%)。所有患者都表现有相对传入性瞳孔障碍。在损伤后4d内开始静脉注射甲基强的松龙,采用Snellen视力表检查视力,绝大部分(56%)患者视力提高超过3行或大于等于0.5(6/12)。在损伤后5d以上才开始用类固醇治疗,视力则没有任何进步。
结论:治疗TON,静脉注射中等到大剂量甲基强的松龙仍将起到重要作用。静脉注射甲基强的松龙治疗TON可能存在伤后4d的关键时期,超过了这个时期,该治疗可能就毫无效果。但还需要有更多的研究来为我们提供有明显统计学意义的数据。 | Soon Lek Yap Angeline Diong Ching Nga Nadir Ali Mohamed Ali Visvaraja Subrayan | 2008 | 国际眼科杂志2008，8，3： | 6 |
| 3 | Comprehensive functional annotation of susceptibility variants identifies genetic heterogeneity between lung adenocarcinoma and squamous cell carcinoma显示文摘Although genome-wide association studies have identified more than eighty genetic variants associated with non-small cell lung cancer(NSCLC)risk,biological mechanisms of these variants remain largely unknown.By integrating a large-scale genotype data of 15581 lung adenocarcinoma(AD)cases,8350 squamous cell carcinoma(SqCC)cases,and 27355 controls,as well as multiple transcriptome and epigenomic databases,we conducted histology-specific meta-analyses and functional annotations of both reported and novel susceptibility variants.We identified 3064 credible risk variants for NSCLC,which were overrepresented in enhancer-like and promoter-like histone modification peaks as well as DNase I hypersensitive sites.Transcription factor enrichment analysis revealed that USF1 was AD-specific while CREB1 was SqCC-specific.Functional annotation and genebased analysis implicated 894 target genes,including 274 specifics for AD and 123 for SqCC,which were overrepresented in somatic driver genes(ER=1.95,P=0.005).Pathway enrichment analysis and Gene-Set Enrichment Analysis revealed that AD genes were primarily involved in immune-related pathways,while SqCC genes were homologous recombination deficiency related.Our results illustrate the molecular basis of both wellstudied and new susceptibility loci of NSCLC,providing not only novel insights into the genetic heterogeneity between AD and SqCC but also a set of plausible gene targets for post-GWAS functional experiments. | Na Qin Yuancheng Li Cheng Wang Meng Zhu Juncheng Dai Tongtong Hong Demetrius Albanes Stephen Lam Adonina Tardon Chu Chen Gary Goodman Stig EBojesen Maria Teresa Landi Mattias Johansson Angela Risch H-Erich Wichmann Heike Bickeboller Gadi Rennert Susanne Arnold Paul Brennan John KField Sanjay Shete Loic Le Marchand Olle Melander Hans Brunnstrom Geoffrey Liu Rayjean JHung Angeline Andrew Lambertus AKiemeney Shan Zienolddiny Kjell Grankvist Mikael Johansson Neil Caporaso Penella Woll Philip Lazarus Matthew BSchabath Melinda CAldrich Victoria LStevens Guangfu Jin David CChristiani Zhibin Hu Christopher IAmos Hongxia Ma Hongbing Shen | 2021 | Frontiers of Medicine2021，15，2： | 3 |
| 4 | MicroRNA-31 functions as an oncogenic microRNA in mouse and human lung cancer cells by repressing specific tumor suppressors显示文摘 | Liu Xi Sempere Lorenzo F Ouyang Haoxu Memoli Vincent A Andrew Angeline S Luo Yue Demidenko Eugene Korc Murray Shi Wei Preis Meir Dragnev Konstantin H Li Hua DiRenzo James Bak Mads Freemantle Sarah J Kauppinen Sakari Dmitrovsky Ethan | 2010 | Journal of Clinical Investigation2010，，4： | 3 |
| 5 | Indonesian nurses' perception of disaster management preparedness显示文摘Purpose: Using a quantitative approach, this study aims to assess Indonesian nurses' perception of their knowledge, skills, and preparedness regarding disaster management. Methods: This study was a descriptive comparison in design. The research samples are Indonesian nurses working in medical services and educational institutions. The variables of nurses' preparedness to cope with disaster victims were measured using the Disaster Preparedness Evaluation Tool (DPET), which was electronically distributed to all nurses in Indonesia. Data were analyzed using a statistical descriptive one-way Analysis of Variance (ANOVA) and t-test with a significance level of 95%. Results: In total, 1341 Indonesian nurses completed this survey. The average scores of preparedness to cope with disasters, the ability to recover from disaster, and evaluation of disaster victims were 3.13, 2.53, and 2.46, respectively. In general, nurses surveyed in this study are less prepared for disaster management, and do not understand their roles either during the phase of disaster preparedness or in coping with a postdisaster situation. Conclusion: Nurses' preparedness and understanding of their roles in coping with disasters are still low in Indonesia. Therefore, their capacity in preparedness, responses, recovery, and evaluation of disasters needs improvement through continuing education. The efforts needed are significant due to potential disasters in Indonesia. | Martono Martono Satino Satino Nursalam Nursalam Ferry Efendi Angeline Bushy | 2019 | Chinese Journal of Traumatology2019，22，1： | 3 |
| 6 | Gut Microbiota Regulates Bile Acid Metabolism by Reducing the Levels of Tauro-beta-muricholic Acid, a Naturally Occurring FXR Antagonist显示文摘 | Sama I. Sayin Annika Wahlstr?m Jenny Felin Sirkku J?ntti Hanns-Ulrich Marschall Krister Bamberg Bo Angelin Tuulia Hy?tyl?inen Matej Ore?i? Fredrik B?ckhed | 2013 | Cell Metabolism2013，，2： | 3 |
| 7 | Poly(N,N-dimethylaminoethyl methacrylate) Grafted Poly(vinyl chloride)s Synthesized via ATRP Process and Their Membranes for Dye Separation显示文摘To functionalize poly(vinyl chloride)(PVC) for various applications, monomers containing tertiary amine group are incorporated into PVC via atom transfer radical polymerization(ATRP) initiated by the labile chlorines in their backbones. The kinetics of synthesis was carefully investigated, and it is proven that the grafting polymerization process can be effectively controlled by regulating the reaction time. The membranes are fabricated using PVC and copolymers by non-solvent induced phase separation(NIPS) process. The hydrophilicity and pore structure of copolymer membranes were enhanced as well, these membranes are endowed with positive charge. When PDMA%(i.e., the PDMA weight percentage in copolymer) is 31.1%, the flux and Victoria blue B rejection are 26.0 L?m?2?h?1(0.5 MPa) and 91.2%, respectively. Thus, the newly synthesized polymer is proven to be a promising material for dye separation with positive charges. | Li-feng Fang Na-chuan Wang Ming-yong Zhou 朱宝库 Li-ping Zhu Angelin Ebanezar John | 2015 | Chinese Journal of Polymer Science2015，33，11： | 3 |
| 8 | The dimensionality of counterproductivity: Are all counterproductive behaviors created equal?显示文摘 | Paul E. Spector Suzy Fox Lisa M. Penney Kari Bruursema Angeline Goh Stacey Kessler | 2005 | Journal of Vocational Behavior2005，，3： | 2 |
| 9 | 紫杉醇局部治疗抑制猪静脉桥新生内膜形成和增厚的实验研究显示文摘目的 :局部药物治疗是一个很好的防治静脉桥病变的策略。本研究用抗细胞增殖药物紫杉醇处理大隐静脉桥后植入猪的颈动脉 ,以观察紫杉醇的抗细胞增殖作用在抑制静脉桥内膜平滑肌细胞增殖、迁移导致内膜形成和增厚的效果。方法 :将 10头猪的 2 0只大隐静脉桥分为两组。治疗组 :将大隐静脉桥 10只置于含有 10 μmol/L浓度的紫杉醇溶液中 (先用该溶液灌洗 )浸泡 1h后植入猪的颈动脉 ,紫杉醇是溶解在 2 5 μl/L的无水酒精中 ,对照组 10只大隐静脉桥置于单纯的酒精中浸泡。 4周后取开放的静脉桥进行组织学分析。结果 :①治疗组静脉桥新生内膜面积 (1 5 9± 0 95 )mm2 ,对照组新生内膜面积高达 (2 43± 1 3 5 )mm2 ,治疗组显著低于对照组 ,两组比较有非常显著的差异 ,P <0 0 1;②治疗组内膜平滑肌细胞密度均值为 (3 681± 193 5 ) /mm2 ,对照组为 (4 60 7± 1993 ) /mm2 ,两组比较有显著性差异 ,P <0 0 5 ;中膜平滑肌细胞密度均值治疗组 (2 13 9± 73 4) /mm2 ,对照组(3 62 9± 3 2 0 7) /mm2 ,两组比较有显著性的差异 ,P <0 0 5。结论 :紫杉醇可显著抑制静脉桥内膜、中膜平滑肌细胞的增殖 ,抑制新生内膜的形成 ,证明紫杉醇可在防治静脉桥闭塞方面发挥独特作用。 | 吴隐雄 Martin H Chamberlain Thomas Johnson Jason L Johnson Andrew C Newby Gianni D Angelin Martin Oberhoff Karl K Karsch | 2003 | 中国循环杂志2003，18，6： | 2 |
| 10 | Does work engagement mediate the rela- tionship between job resources and job performance of employees? 显示文摘 | CHUNG N G ANGELINE T | 2010 | African Journal of Business Management2010，4，9： | 1 |
| 11 | Hallervorden- Spatz dis ease:clinical and MRI study of 11 cases diagnosed in life显示文摘 | NARDOCCI N RUMI V | 1992 | J Neurol1992，239，： | 1 |
| 12 | Butein downregulates chemokine receptor CXCR4 expression and function through suppression of NF-κB activation in breast and pancreatic tumor cells显示文摘 | Angeline Wei Ling Chua Hui Sin Hay Peramaiyan Rajendran Muthu K. Shanmugam Feng Li Pradeep Bist Evelyn S.C. Koay Lina H.K. Lim Alan Prem Kumar Gautam Sethi | 2010 | Biochemical Pharmacology2010，，10： | 1 |
| 13 | A high Performance Tool forThe Simulation of the Dynamic Pantograph–catenaryInteraction显示文摘 | Angelines Alberto etc | 2008 | Mathematics and Computers inSimulation2008，，3： | 1 |
| 14 | Chemical control of the heptotoxic phytoplanton blooms: implication for human health显示文摘 | Angeline KY Ellie E Dadid S | 1995 | Water Res1995，29，： | 1 |
| 15 | Increased prevalence of atherosclerotic wall changes in patients with hyperlipidaemia after renal transplantation显示文摘 | Fehrman Ekholm I Angelin B | 1996 | J Intern Med1996，239，： | 1 |
| 16 | Kinectin-Kinesin Binding Domains and Their Effects on Organelle Motility显示文摘 | Ong LL Angeline PL Connie PN | 2000 | The Journal Of Biological Chemistry2000，275，32： | 1 |
| 17 | Circulating intestinal fibroblast growth factor 19 has a pronounced diurnal variation and modulates hepatic bile acid synthesis in man显示文摘 | Lundasen T Galman C Angelin B | 2006 | J Intern Med2006，260，6： | 1 |
| 18 | Endothelial ni- tric oxide synthase gene polymorphism G894T and acute myocardial infarction显示文摘 | Angeline T Krithiga HR Wisabe C | 1998 | Hypertension1998，32，3： | 1 |
| 19 | Cholesterol regulates ACAT2 gene expression and enzyme activity in human hepatoma cells显示文摘 | Pramfalk C Angelin B Eriksson M | 2007 | Biochena Biophy Res Commun2007，364，2： | 1 |
| 20 | Qinidine reduces biliary clearance of digoxin in man显示文摘 | Angelin B Arvidsson A Dahlqvist R | 1987 | Eur J Clin Invest1987，17，： | 1 |
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