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| 1 | Welcome Back to the Pre-Penicillin Era.Why We Desperately Need New Strategies in the Battle Against Bacterial Pathogens显示文摘In 2023,one hundred years will have passed since penicillin was discovered.My parents'generation was bor around the time penicillin was introduced(in 1942),raising their children when the last class of antibiotics was introduced(Daptomycin in the late 1980s),and recently saw major players of the pharmaceutical industry abandon their research programs on novel antibiotics.1,2 In the span of one lifetime,mankind has experienced the tremendous success of antibiotics and the realization of the horrific consequences of their failure,with over 10 million deaths predicted by 2050 due to multidrug-resistant infections.3 With the rise of multidrug resistant pathogens,resistant to many if not all compounds,it scems the golden era of antibiotics has lasted less than one century. | Sebastian Leptihn | 2019 | Infectious Microbes & Diseases2019，1，2： | 4 |
| 2 | The natural history of Ebola virus in Africa显示文摘 | Xavier Pourrut Brice Kumulungui Tatiana Wittmann Ghislain Moussavou André Délicat Philippe Yaba Dieudonné Nkoghe Jean-Paul Gonzalez Eric Maurice Leroy | 2005 | Microbes and Infection2005，，7： | 4 |
| 3 | Comparison of aerobic denitrification under high oxygen atmosphere by Thiosphaerapantotropha ATCC 35512 and Pseudomonas stutzeri SU2 newly isolated from the activated sludge of a piggery wastewater treatment system显示文摘 | Su JJ Liu BY Liu CY | | J Appl Microb0，，： | 4 |
| 4 | Microbes, Microbiota, and Colon Cancer显示文摘 | Cynthia L. Sears Wendy S. Garrett | 2014 | Cell Host & Microbe2014，，3： | 3 |
| 5 | Air pollution effects on the gut microbiota显示文摘 | Saad Y Salim Gilaad G Kaplan Karen L Madsen | 2014 | Gut Microbes2014，，： | 3 |
| 6 | The Treatment-Naive Microbiome in New-Onset Crohn’s Disease显示文摘 | Dirk Gevers Subra Kugathasan Lee A. Denson Yoshiki Vázquez-Baeza Will Van Treuren Boyu Ren Emma Schwager Dan Knights Se Jin Song Moran Yassour Xochitl C. Morgan Aleksandar D. Kostic Chengwei Luo Antonio González Daniel McDonald Yael Haberman Thomas Walter | 2014 | Cell Host & Microbe2014，，： | 3 |
| 7 | Probiotics for human lactational mastitis显示文摘 | L. Fernández R. Arroyo I. Espinosa M. Marín E. Jiménez J.M. Rodríguez | 2014 | Beneficial Microbes (-)2014，，1： | 3 |
| 8 | The Mitochondrial Targeting Chaperone 14-3-3ε Regulates a RIG-I Translocon that Mediates Membrane Association and Innate Antiviral Immunity显示文摘 | Helene Minyi Liu Yueh-Ming Loo Stacy M. Horner Gregory A. Zornetzer Michael G. Katze Michael Gale | 2012 | Cell Host & Microbe2012，，5： | 3 |
| 9 | Kinetic calculations in the enzymic resolution of D-amino acids显示文摘 | Bodalo A Gomez J L | 1999 | Enzyme Microb Technol1999，24，1： | 2 |
| 10 | Autophagy Induction by the Pathogen Receptor CD46显示文摘 | Pierre-Emmanuel Joubert Grégory Meiffren Isabel Pombo Grégoire Guillemette Pontini Clémence Richetta Monique Flacher Olga Azocar Pierre-Olivier Vidalain Marc Vidal Vincent Lotteau Patrice Codogno Chantal Rabourdin-Combe Mathias Faure | 2009 | Cell Host & Microbe2009，，4： | 2 |
| 11 | Composition and Three-Dimensional Architecture of the Dengue Virus Replication and Assembly Sites显示文摘 | Sonja Welsch Sven Miller Ines Romero-Brey Andreas Merz Christopher K.E. Bleck Paul Walther Stephen D. Fuller Claude Antony Jacomine Krijnse-Locker Ralf Bartenschlager | 2009 | Cell Host & Microbe2009，，： | 2 |
| 12 | Catheter-related infections显示文摘 | Philippe Eggimann Hugo Sax Didier Pittet | 2004 | Microbes and Infection2004，，11： | 2 |
| 13 | Diet, microbial virulence, and Helicobacter pylori-induced gastric cancer显示文摘 | Timothy L Cover Richard M Peek Jr | 2013 | Gut Microbes2013，，： | 2 |
| 14 | Effects of lignocellulosic degradation products on ethanol fermentations of glucose and xylose by Saccharomyces cerevisiae, Zymomonas mobilis, Pichia stipititis and Candida shehatae显示文摘 | Delgens JP Moletta R Navarro JM | 1996 | Enzyme Microb Technol1996，19，： | 2 |
| 15 | Epidemiology and Control of Brucellosis in China显示文摘 | Shang Deqiu | 2002 | Vet Microb Inter J2002，90，14： | 2 |
| 16 | Tertiary Structure-Function Analysis Reveals the Pathogenic Signaling Potentiation Mechanism of Helicobacter pylori Oncogenic Effector CagA显示文摘 | Takeru Hayashi Miki Senda Hiroko Morohashi Hideaki Higashi Masafumi Horio Yui Kashiba Lisa Nagase Daisuke Sasaya Tomohiro Shimizu Nagarajan Venugopalan Hiroyuki Kumeta Nobuo N. Noda Fuyuhiko Inagaki Toshiya Senda Masanori Hatakeyama | 2012 | Cell Host & Microbe2012，，1： | 2 |
| 17 | Autophagy is involved in the early step of Japanese encephalitis virus infection显示文摘 | Jin-Kun Li Jian-Jong Liang Chin-Len Liao Yi-Ling Lin | 2011 | Microbes and Infection2011，，2： | 2 |
| 18 | Influenza A Virus NS1 Targets the Ubiquitin Ligase TRIM25 to Evade Recognition by the Host Viral RNA Sensor RIG-I显示文摘 | Michaela Ulrike Gack Randy Allen Albrecht Tomohiko Urano Kyung-Soo Inn I-Chueh Huang Elena Carnero Michael Farzan Satoshi Inoue Jae Ung Jung Adolfo García-Sastre | 2009 | Cell Host & Microbe2009，，5： | 2 |
| 19 | Host-Mediated Inflammation Disrupts the Intestinal Microbiota and Promotes the Overgrowth of Enterobacteriaceae显示文摘 | Claudia Lupp Marilyn L. Robertson Mark E. Wickham Inna Sekirov Olivia L. Champion Erin C. Gaynor B. Brett Finlay | 2007 | Cell Host & Microbe2007，，2： | 2 |
| 20 | Aedes albopictus , an arbovirus vector: From the darkness to the light显示文摘 | C. Paupy H. Delatte L. Bagny V. Corbel D. Fontenille | 2009 | Microbes and Infection2009，，14： | 2 |
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