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| 1 | Variation of head and facial morphological characteristics with increased age of Han in Southern China显示文摘We investigated 13940 (6735 male, 7250 female) adult head and facial physical attributes from 19 different Han ethnic groups in 10 southern-China provinces, and calculated 12 head and facial indexes. Indexes were used to analyze the variation of head and facial morphological characteristics with increased age. Results showed that as age increases: (1) Head breadth, minimum frontal breadth, face breadth, interocular breadth, external biocular breadth, lip height, lip thickness, head circumference, auricular height, length-breadth head index, length-height head index, and lip-index values decline significantly in a linear fashion. (2) Nose breadth, mouth breadth, morphological facial height, upper-lip height, physiognomic ear length, physiognomic ear breadth, visor skin-fold, and vertical head-facial index values significantly increase in a linear fashion. | LI YongLan ZHENG LianBin YU KeLi LU ShunHua ZHANG XingHua LI YuLing WANG Yang XUE Hong DENG Wei | 2013 | Chinese Science Bulletin2013，58，4： | 20 |
| 2 | Protective effect of Angelica sinensis on cerebral neurons from rat embryos under hypoxia显示文摘BACKGROUND: The enhanced expression of c-Fos protein in nerve cells after hypoxia is the marker for converting extracellular hypoxia information to intracellular changes at hypoxia, and it is suspected that the increase of c-Fos protein can lead to the synthesis and excretion of related neurotrophic factor and nerve growth factor. However, it is still unclear what functional changes of nerve cells are induced by the increase of c-Fos protein at hypoxia, and whether it is good for the survival of damaged neurons. OBJECTIVE: To observe the expression of c-Fos in the cerebral neurons from embryos of rats with hypoxia in uterus, and investigate the pathway for the protective effect of Angelica sinensis injection on the cerebral neurons from rat embryos under hypoxia. DESIGN: A completely randomized controlled study. SETTING: Department of Histology and Embryology, Luzhou Medical College. MATERIALS: Twelve female Wistar rats in oestrum and 1 male adult Wistar rat with body mass of 220 to 250 g were selected. Rabbit-anti-rat neuro-specific enolase (NSE) and rabbit-anti-rat c-Fos were purchased from Wuhan Boster Biological Technology Co., Ltd.; Double-staining kit was bought from Beijing Zhongshan Golden Bridge Biotechnology Co., Ltd. Angelica sinensis injection was produced by the Department of Pharmacy, the Second Affiliated Hospital of Hubei Medical University. METHODS: The experiments were completed in the experimental animal center and the Department of Histology and Embryology of Luzhou Medical College from December 2004 to December 2005. ① Twelve adult female Wistar rats in oestrum and 1 male Wistar rat were housed in one rearing cage. The appearance of vaginal embolus at 8:00 in the next morning was recorded as 0 day of pregnancy and the rats were recorded for 15 days, and they were divided randomly into three groups, control group (n =4), hypoxia group (n =4) and Angelica group (n =4). The pregnant rats in the hypoxia group were firstly injected with saline (8 mL/kg), then put into 2 L wide-mouthed bottle containing 100 g sodalime, and then the lid of the bottle was closed tightly to induce hypotonic hypoxia for 1 hour followed by 1-hour re-oxygenation. The pregnant rats were killed under anesthesia, and then fetuses were taken out by rapid cesarean. Part of the brain tissues were exposed and then fixed in formaldehyde (40 g/L). The pregnant rats in the Angelica group were treated the same as those in the hypoxia group except that saline was replaced by 250 g/L Angelica sinensis injection which was injected via caudal vein (8 mL/kg). The rats in the control group were injected with saline (8 mL/kg) slowly via caudal vein, but not put into the wide-mouthed bottle for hypoxia, and then the brain tissues were removed and fixed as those in the hypoxia group after 1 hour. ② Twenty embryos from rats were chosen randomly in each group and then routinely embedded in paraffin. Paraffin sections of 4 μm thick were prepared through the anterior fontanelle of head of the fetal rats. The sections were immunohistologically stained with c-Fos/NSE. ③ The one-way analysis of variance (ANOVA) was used to compare the differences of measurement data among the groups, and the q test was applied in the two-two comparison. MAIN OUTCOME MEASURES: The numbers of c-Fos and c-Fos/NSE positive neurons in cerebrum from rat embryos were observed. RESULTS: ① Numbers of NSE positive neurons in cerebrum of rat embryos in the control group, hypoxia group and Angelica group were (84.3±9.0), (90.2±12.5) and (86.7±9.7) cells/high power field (P > 0.05). ② The number of c-Fos/NSE positive neurons was more in the hypoxia group than in the control group and Angelica group [(38.4±5.28), (11.35±2.67), (20.65±4.07) cells/high power field, q =29.17, 19.14, P < 0.05]. CONCLUSION: Hypoxia can stimulate the expression of c-Fos in cerebral neurons from rat embryos. Angelica sinensis injection could reducing the damage of hypoxia to neurons and play a neuroprotective roleby decreasing the expression of c-Fos protein in hypoxic neurons. | Yuling Wu Hongxian Zhao Hong Yu | 2007 | Neural Regeneration Research2007，2，1： | 7 |
| 3 | Particulate Matter Air Pollution and Cardiovascular Disease: An Update to the Scientific Statement From the American Heart Association显示文摘 | Robert D. Brook Sanjay Rajagopalan C. Arden Pope Jeffrey R. Brook Aruni Bhatnagar Ana V. Diez-Roux Fernando Holguin Yuling Hong Russell V. Luepker Murray A. Mittleman Annette Peters David Siscovick Sidney C. Smith Laurie Whitsel Joel D. Kaufman | 2010 | Circulation2010，，21： | 4 |
| 4 | Modeling and Path Generation Approaches for Crowd Simulation Based on Computational Intelligence显示文摘 | LIU Hong SUN Yuling LI Yuanyuan | 2012 | Chinese Journal of Electronics2012，21，4： | 3 |
| 5 | Heart Disease and Stroke Statistics—2006 Update: A Report From the American Heart Association Statistics Committee and Stroke Statistics Subcommittee显示文摘 | Thomas Thom Nancy Haase Wayne Rosamond Virginia J. Howard John Rumsfeld Teri Manolio Zhi-Jie Zheng Katherine Flegal Christopher O’Donnell Steven Kittner Donald Lloyd-Jones David C. Goff Yuling Hong Robert Adams Gary Friday Karen Furie Philip Gorelick Bret | 2006 | Circulation2006，，6： | 3 |
| 6 | Particulate Matter Air Pollution and Cardiovascular Disease: An Update to the Scientific Statement From the American Heart Association显示文摘 | Robert D. Brook Sanjay Rajagopalan C. Arden Pope Jeffrey R. Brook Aruni Bhatnagar Ana V. Diez-Roux Fernando Holguin Yuling Hong Russell V. Luepker Murray A. Mittleman Annette Peters David Siscovick Sidney C. Smith Laurie Whitsel Joel D. Kaufman | 2010 | Circulation2010，，21： | 2 |
| 7 | Air Pollution and Cardiovascular Disease: A Statement for Healthcare Professionals From the Expert Panel on Population and Prevention Science of the American Heart Association显示文摘 | Robert D. Brook Barry Franklin Wayne Cascio Yuling Hong George Howard Michael Lipsett Russell Luepker Murray Mittleman Jonathan Samet Sidney C. Smith Ira Tager | 2004 | Circulation: Journal of the American Heart Association2004，，21： | 2 |
| 8 | New NIR-Ⅱ dyes without a benzobisthiadiazole core显示文摘Fluorescent NIR-Ⅱ imaging has a wide range of benefits not offered by other imaging modalities for biomedical applications, derived from its combination of high spatial and temporal resolution due to reduced photon absorption, scattering and tissue auto-fluorescence. Compared to the well-studied NIR-Ⅰ small-molecule fluorophores, the structures of NIR-Ⅱ fluorophores are scarce. To date, the main fluorophore units are composed of conjugated π system with a benzobisthiadiazole(BBTD) core and donor-acceptor-donor(D-A-D) structure. Herein, researchers Yang et al. and Zhang et al. have reported new NIR-Ⅱ probes ECX and FD-1080 respectively without a BBTD core which are highlighted. | Hui Zhou Yuling Xiao Xuechuan Hong | 2018 | Chinese Chemical Letters2018，29，10： | 2 |
| 9 | Markers of Inflammation and Cardiovascular Disease: Application to Clinical and Public Health Practice: A Statement for Healthcare Professionals From the Centers for Disease Control and Prevention and the American Heart Association显示文摘 | Thomas A. Pearson George A. Mensah R. Wayne Alexander Jeffrey L. Anderson Richard O. Cannon Michael Criqui Yazid Y. Fadl Stephen P. Fortmann Yuling Hong Gary L. Myers Nader Rifai Sidney C. Smith Kathryn Taubert Russell P. Tracy Frank Vinicor | 2003 | Circulation: Journal of the American Heart Association2003，，3： | 2 |
| 10 | Value of three-dimensional contrast-enhanced Ultrasound in the diagnosis of small adnexal masses显示文摘 | Xiang Hong Huang Rui Cheng Jingxin Gulinaer Shahai Hu rong Feng Yuling Liu Hui | 2012 | Ultrasound in Medicine & Biology2012，，： | 1 |
| 11 | Incorporation of Lysine-Containing Copolymer with Polyurethane Affording Biomaterial with Specific Adsorption of Plasminogen显示文摘新奇 biomaterial 通过包含离氨酸的共聚物的物理加入基于聚氨酯(PU ) 被准备改进它的 hemocompatibility 和 plasminogen 的表面识别。包含离氨酸的共聚物经由 2-ethylhexyl methacrylate ( EHMA )的 copolymerization 被综合, oligo (乙烯乙二醇)甲基醚 methacrylate ( OEGMA )和 6-tert-butoxycarbonyl amino-2-( 2-methyl-acryloylamino ) -hexanoic 酸tert丁基酉旨( Lys (P)麻省),在共聚物在离氨酸残余上由 COOH 和 -NH2 组的 deprotection 列在后面。共聚物的作文能被改变单体调整喂比率。三个部件贡献分别地与 PU,到 nonspecific 蛋白质吸附的抵抗和 plasminogen 的特定的绑定改进相容性。向 plasminogen 的有约束力的能力在共聚物与离氨酸内容增加了。这条途径与改进 hemocompatibility 和特定的 biomolecules 的表面识别为新奇 biomaterials 的产生说明一个简单方法。 | Haichao Xu Yafei Luan Zhaoqiang Wu Xinming Li Yuling Yuan Xiaoli Liu Lin Yuan Dan Li Hong Chen | 2014 | Chinese Journal of Chemistry2014，32，1： | 1 |
| 12 | Particulate Matter Air Pollution and Cardiovascular Disease: An Update to the Scientific Statement From the American Heart Association显示文摘 | Robert D. Brook Sanjay Rajagopalan C. Arden Pope Jeffrey R. Brook Aruni Bhatnagar Ana V. Diez-Roux Fernando Holguin Yuling Hong Russell V. Luepker Murray A. Mittleman Annette Peters David Siscovick Sidney C. Smith Laurie Whitsel Joel D. Kaufman | 2010 | Circulation2010，，21： | 1 |
| 13 | Defining and Setting National Goals for Cardiovascular Health Promotion and Disease Reduction: The American Heart Association?s Strategic Impact Goal Through 2020 and Beyond显示文摘 | Donald M. Lloyd-Jones Yuling Hong Darwin Labarthe Dariush Mozaffarian Lawrence J. Appel Linda Van Horn Kurt Greenlund Stephen Daniels Graham Nichol Gordon F. Tomaselli Donna K. Arnett Gregg C. Fonarow P. Michael Ho Michael S. Lauer Frederick A. Masoudi Ro | 2010 | Circulation2010，，4： | 1 |
| 14 | Transcriptional and post‑transcriptional regulation of RNAi‑related gene expression during plant‑virus interactions显示文摘As sessile organisms,plants encounter diverse invasions from pathogens including viruses.To survive and thrive,plants have evolved multilayered defense mechanisms to combat virus infection.RNAi,also known as RNA silencing,is an across-kingdom innate immunity and gene regulatory machinery.Molecular framework and crucial roles of RNAi in antiviral defense have been well-characterized.However,it is largely unknown that how RNAi is transcriptionally regulated to initiate,maintain and enhance cellular silencing under normal or stress conditions.Recently,insights into the transcriptional and post-transcriptional regulation of RNAi-related genes in different physiological processes have been emerging.In this review,we integrate these new findings to provide updated views on how plants modulate RNAi machinery at the(post-)transcriptional level to respond to virus infection. | Qian Gong Yunjing Wang Zhenhui Jin Yiguo Hong Yule Liu | 2022 | Stress Biology2022，2，1： | 1 |
| 15 | Markers of Inflammation and Cardiovascular Disease: Application to Clinical and Public Health Practice: A Statement for Healthcare Professionals From the Centers for Disease Control and Prevention and the American Heart Association显示文摘 | Thomas A. Pearson George A. Mensah R. Wayne Alexander Jeffrey L. Anderson Richard O. Cannon Michael Criqui Yazid Y. Fadl Stephen P. Fortmann Yuling Hong Gary L. Myers Nader Rifai Sidney C. Smith Kathryn Taubert Russell P. Tracy Frank Vinicor | 2003 | Circulation: Journal of the American Heart Association2003，，3： | 1 |
| 16 | Predictive value for the Chinese population of the framingham CHD risk assessment tool compared with the Chinese multi-provincial cohort study显示文摘 | Jing Liu Yuling Hong | 2004 | JAMA2004，122，21： | 1 |
| 17 | Forecasting the Future of Cardiovascular Disease in the United States: A Policy Statement From the American Heart Association显示文摘 | Paul A. Heidenreich Justin G. Trogdon Olga A. Khavjou Javed Butler Kathleen Dracup Michael D. Ezekowitz Eric Andrew Finkelstein Yuling Hong S. Claiborne Johnston Amit Khera Donald M. Lloyd-Jones Sue A. Nelson Graham Nichol Diane Orenstein Peter W.F. Wilso | 2011 | Circulation2011，，8： | 1 |
| 18 | Defining and setting national coals for cardiovascular health promotion and disease reduction : The A- merican Heart Association's Strategic Impact Coal Through 2020 and Beyond显示文摘 | Donld M Lloyd-Jones Yuling Hong | 2010 | Circulation2010，，： | 1 |
| 19 | Defining and setting national coals for cardiovascular health promotion and disease reduction : The A- merican Heart Association's Strategic Impact Coal Through 2020 and Beyond显示文摘 | Donald M Lloyd-Jones Yuling Hong | 2010 | Circulation2010，，： | 1 |
| 20 | Expression of c-Fos protein and nitricoxide synthase in neurons of cerebral cortex from fetal rats in hypoxia and protective role of Angelica sinensis显示文摘BACKGROUND: Both c-Fos protein and nitricoxide synthase (NOS) have been used as general indexes in relative research about neurons, but it is lack of reports that c-Fos protein and NOS are applied synchronously to study the neurons of hypoxic fetal rats in uterus. OBJECTIVE: To study the effect of hypoxia in uterus on the expression of c-Fos protein and NOS in neurons of cerebral cortex from fetal rats and whether Angelica sinensis has the protective effect on these neurons in hypoxia. DESIGN: Randomized control experiment. SETTING: Department of Histology and Embryology, Luzhou Medical College. MATERIALS: Twelve adult female Wistar rats in oestrum and 1 male Wistar rat with bodymass from 220 to 250 g were chosen. Parenteral solution of Angelica sinensis mainly contained angelica sinensis, 10 mL/ampoule, was provided by Department of Agent of the Second Hospital Affiliated to Hubei Medical University (batch number: 01062310). METHODS: This experiment was completed in the Department of Histology and Embryology of Luzhou Medical College from September 2003 to June 2004. ① Twelve adult female Wistar rats in oestrum and 1 male Wistar rat were housed in one rearing cage. Vaginal embolus was performed on conceive female rat at 8:00 am next day. On the 15th conceiving day, all conceiving rats were divided randomly into three groups: control group, hypoxia group and Angelica group with 4 in each group. Rats in hypoxia group and Angelica group were modeled with hypotonic hypoxia in uterus. Angelica group: Rats were injected with 8 mL/kg Angelica sinensis injection through caudal veins before hypoxia. Hypoxia group: Rats were injected with the same volume of saline. Control group: Rats were not modeled and fed with normal way. ② Twenty embryos of rats were chosen randomly from each group and then routinely embedded in paraffin. Paraffin sections were cut from the brain of embryos to anterior fontanelle. Double-label staining was used to detect the expression of nNOS and c-Fos in neurons of cerebral cortex from embryos of rats. OLYMPUS Bx-50 microscope was used to observe sections and DP12 digit camera was also used under 400 times to detect types of cells. Under microscope, the number of c-Fos, NOS, c-Fos/NOS positive neurons in cerebral cortex from embryos of rats were counted in 2 fields with magnification of 400 in one section per animal. ③ The data in experiments were analyzed by one-way analysis of variance (ANOVA) followed by q test. MAIN OUTCOME MEASURES: ① Results of immunohistochemical double-label staining of c-Fos/NOS from cerebral cortex; ② Comparison of amount immunohistochemical double-label staining of c-Fos/NOS positive cells from cerebral cortex. RESULTS: ① The positive NOS cells and c-Fos/NOS cells in the three groups were mainly distributed in cerebral cortex, but positive c-Fos neurons were not observed. ② Positive NOS cells and c-Fos/NOS cells in hypoxia group were more than those in control group (76.55±12.02, 50.45±10.39; 33.35±7.42, 26.35 ±6.67, P < 0.05), but those in Angelica group were less than those in hypoxia group (51.70±9.82, 35.65 ±8.37, P < 0.05). CONCLUSION: Hypoxia can stimulate the increase of expression of c-Fos protein and NOS in neurons of cerebral cortex. However, Angelica sinensis can decrease this expression so as to play a protective role in cerebral neurons of hypoxic fetal rats. | Hong Yu Hongxian Zhao Yuling Wu | 2006 | Neural Regeneration Research2006，1，1： | 1 |
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