|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Current status of diagnosis and treatment of bladder cancer in China-Analyses of Chinese Bladder Cancer Consortium database显示文摘Objective:To investigate current status of diagnosis and treatment of bladder cancer in China.Methods:A database was generated by Chinese Bladder Cancer Consortium(CBCC).From January 2007 to December 2012,14,260 cases from 44 CBCC centers were included.Data of diagnosis,treatment and pathology were collected.Results:The average age was 63.5 year-old and most patients were male(84.3%).The most common histologic types were urothelial carcinoma(91.4%),adenocarcinoma(1.8%),and squamous carcinoma(1.9%).According to 1973 and 2004 WHO grading system,42.0%,41.0%,and 17.0% of patients were grade 1,2,and 3,and 16.0%,48.7%,and 35.3% of patients were papillary urothelial neoplasms of low malignant potential,low,and high grade,respectively.Non-muscle invasive bladder cancer(NMIBC)and muscle invasive bladder cancer(MIBC)were 25.2% and 74.1%,respectively(0.8% not clear).Carcinoma in situ was only 2.4%.Most patients were diagnosed by white-light cystoscopy with biopsy(74.3%).Fluorescence and narrow band imaging cystoscopy had additional detection rate of 1.0% and 4.0%,respectively.Diagnostic transurethral resection(TUR)provided detection rate of 16.9%.Most NMIBCs were treated with TUR(89.2%).After initial TUR,2.6%accepted second TUR,and 45.7%,69.9%,and 58.7% accepted immediate,induced,and maintenance chemotherapy instillation,respectively.Most MIBCs were treated with radical cystectomy(RC,59.7%).Laparoscopic RCs were 35.1%,while open RC 63.4%.Extended and standard pelvic lymph node dissection were 7% and 66%,respectively.Three most common urinary diversions were orthotopic neobladder(44%),ileal conduit(31%),and ureterocutaneostomy(23%).Only 2.3% of patients accepted neo-adjuvant chemotherapy and only 18%of T3 and T4 patients accepted adjuvant chemotherapy.Conclusion:Disease characteristics are similar to international reports,while differences of diagnosis and treatment exist.This study can provide evidences for revisions of the guideline on bladder cancer in China. | Kaiwen Li Tianxin Lin 无 Wei Xue Xin Mu Enci Xu Xu Yang Fubao Chen Guangyong Li Lulin Ma Guoliang Wang Chaozhao Liang Haoqiang Shi Ming Li Mao Tang Xueyi Xue Yisong Lv Yaoliang Deng Chengyang Li Zhiwen Chen Xiaozhou Zhou Fengshuo Jin Xudong Liu Jinxin Wei Lei Shi Xin Gou Weiyang He Liqun Zhou Lin Cai Baiye Jin Guanghou Fu Xiangbo Kong Hongyan Sun Ye Tian Lang Feng Tiejun Pan Yiyi Wu Dongwen Wang Hailong Hao Benkang Shi Yaofeng Zhu Qiang Wei Ping Han Changli Wu Dawei Tian Zhangqun Ye Zheng Liu Zhiping Wang Junqiang Tian Lin Qi Minfeng Chen Wei Li Jinchun Qi Gongxian Wang Longlong Fu Zhaolin Sun Guangheng Luo Zhoujun Shen Zhaowei Zhu Jinchun Xing Zhun Wu Dong Wei Xin Chen Yanqun Na Hongfeng Guo Chunxi Wang Zhihua Lu Chuize Kong Yang Liu Jin Yang Jianyun Hu Xin Gao Jielin Li Changjun Yin Pu Li Shan Chen Zhen Du Jiongming Li Yongji Yan Xu Zhang Shuang Huang Fangjian Zhou Zhiling Zhang Yinghao Sun Shuxiong Zeng Song Cen Jiaquan Zhou Hanzhong Li Jin Wen Jian Huang | 2015 | Asian Journal of Urology2015，2，2： | 21 |
| 2 | Surveillance on the Immune Effectiveness of Quadrivalent and Trivalent Split Influenza Vaccines—Shenzhen City and Changzhou City,China,2018–2019显示文摘Summary What is already known about this topic?Vaccinations are the most effective way to prevent influenza virus infections and severe outcomes.Influenza vaccine effectiveness can vary by seasons.What is added by this report?This report monitors the antibody level among the population over time after administration of the quadrivalent or trivalent split influenza vaccine.What are the implications for public health practice?Real-time monitoring of serum antibody changes after vaccination provides important data for the development of reasonable and effective strategies for influenza prevention and control. | Liumei Shu Jie Zhang Xiang Huo Cong Chen Shisong Fang Kexin Zong Yuanyuan Guo Yingze Zhao Jun Zhang Changjun Bao Junjie Xia Fengcai Zhu Dayan Wang Guizhen Wu George F.Gao William J.Liu | 2020 | China CDC weekly2020，2，21： | 5 |
| 3 | Endothelial PDGF-BB/PDGFR-βsignaling promotes osteoarthritis by enhancing angiogenesis-dependent abnormal subchondral bone formation显示文摘The mechanisms that coordinate the shift from joint homeostasis to osteoarthritis(OA)remain unknown.No pharmacological intervention can currently prevent the progression of osteoarthritis.Accumulating evidence has shown that subchondral bone deterioration is a primary trigger for overlying cartilage degeneration.We previously found that H-type vessels modulate aberrant subchondral bone formation during the pathogenesis of OA.However,the mechanism responsible for the elevation of H-type vessels in OA is still unclear.Here,we found that PDGFR-βexpression,predominantly in the CD31^(hi)Emcn^(hi) endothelium,was substantially elevated in subchondral bones from OA patients and rodent OA models.A mouse model of OA with deletion of PDGFR-βin endothelial cells(ECs)exhibited fewer H-type vessels,ameliorated subchondral bone deterioration and alleviated overlying cartilage degeneration.Endothelial PDGFR-βpromotes angiogenesis through the formation of the PDGFR-β/talin1/FAK complex.Notably,endothelium-specific inhibition of PDGFR-βby local injection of AAV9 in subchondral bone effectively attenuated the pathogenesis of OA compared with that of the vehicle-treated controls.Based on the results from this study,targeting PDGFR-βis a novel and promising approach for the prevention or early treatment of OA. | Zhuang Cui Hangtian Wu Ye Xiao Ting Xu Junjie Jia Hancheng Lin Rongmin Lin Kun Chen Yihuang Lin Kaiqun Li Xiaohu Wu Changjun Li Bin Yu | 2022 | Bone Research2022，10，4： | 4 |
| 4 | Preliminary Results of Acoustic Radiation Force Impulse (ARFI) Ultrasound Imaging of Breast Lesions显示文摘 | Wei Meng Guangchen Zhang Changjun Wu Guozhu Wu Yan Song Zhaoling Lu | 2011 | Ultrasound in Medicine & Biology2011，，9： | 2 |
| 5 | Wide-field in situ multiplexed Raman imaging with superresolution显示文摘Because of the fingerprint-like specificity of its characteristic spectrogram, Raman spectral imaging has been applied widely in various research areas. Using a combination of structured illumination with the surface-enhanced Raman scattering(SERS) technique, wide-field Raman imaging is developed with a significant improvement in spatial resolution. As a result of the relatively narrow Raman characteristic peaks, optically encoded SERS nanoparticles can be used to perform multiplexed imaging. The results show excellent superresolution wide-field multiplexed imaging performance. The developed technique has extraordinary potential for applications in biological imaging and other related fields. | HOUKAI CHEN XIAOJING WU YUQUAN ZHANG YONG YANG CHANGJUN MIN SIWEI ZHU XIAOCONG YUAN QIAOLIANG BAO JING BU | 2018 | Photonics Research2018，6，6： | 2 |
| 6 | Effect of Mg on Microstructure and Growth Kinetics of Zn-22.3Al-1.1Si Coating显示文摘The effects of Mg on the microstructure and growth kinetics of the hot-dip Zn-22.3 Al-1.1 Si-x Mg(x = 0, 0.2, 0.4, and 0.6) coatings were investigated in detail. Scanning electron microscopy with energy dispersive spectroscopy and X-ray diffraction studies revealed the presence of η-Zn, α-Al, Zn/Al eutectoid,(Si), Al/Si eutectic, and Zn/Al/Mg_2 Zn11 ternary eutectic on the top surface of these Mg-containing coatings. Especially, a small amount of MgZn2 phase appears in top surface of Zn-22.3 Al-1.1 Si-0.6 Mg coating. Five phases are found in the alloy layers, i e, Fe_2 Al_5, FeAl_3, τ_(5C), τ_(5H), and τ_1. The addition of 0.2% Mg can delay the emergence of FeAl_3 phase. When the Mg content is more than 0.2%, the outer layers of coating change from τ_(5C) to τ_(5H) phase. The growth of the inhibition layer is diffusion controlled for various Mg content baths. Mg improves the corrosion resistance of the Mg-containing coatings, and the Zn-22.3 Al-1.1 Si-0.6 Mg coating possesses the highest protective properties. | 涂浩 WEI Dasheng ZHOU Shengjie LIU Ya WU Changjun WANG Jianhua 苏旭平 | 2019 | Journal of Wuhan University of Technology(Materials Science)2019，34，2： | 2 |
| 7 | Preliminary Results of Acoustic Radiation Force Impulse (ARFI) Ultrasound Imaging of Breast Lesions显示文摘 | Wei Meng Guangchen Zhang Changjun Wu Guozhu Wu Yan Song Zhaoling Lu | 2011 | Ultrasound in Medicine & Biology2011，，9： | 2 |
| 8 | Experimental investigation of the Zn-Fe-V system at450℃显示文摘 | Wu Changjun Su Xuping Liu Daniel | 2010 | International Journal of MaterialsResearch2010，101，12： | 1 |
| 9 | The C_(6)D_(6)detector system on the Back-n beam line of CSNS显示文摘Introduction The neutron capture cross sections are very important in the field of nuclear device design and basic physics research.Hydrogen-free liquid scintillator such as C_(6)D_(6)detectors are widely used in the neutron capture cross-sectional measurements for the low neutron sensitivity and fast time response.The Back-n white neutron source at China Spallation Neutron Source is the first spallation white neutron source in China,and it is suitable for neutron capture cross-sectional measurement.Materials and methods A C_(6)D_(6)detector system was built in the Back-n experimental station.The pulse height weighting technique was used to determine the system’s detection efficiency.The response to gamma rays of the C_(6)D_(6)detector was measured,and the energy resolution function was determined.Monte Carlo simulation with Geant4 code was carried out to get the weighting function of this C_(6)D_(6)detector system.Additionally,the systematic uncertainty of the weighting function was also determined.Conclusion According to the experimental and simulation results,this C_(6)D_(6)detector system can be used to measure neutron capture cross section. | Jie Ren Xichao Ruan Jie Bao Guangyuan Luan Wei Jiang Qi An Huaiyong Bai Ping Cao Qiping Chen Yonghao Chen Pinjing Cheng Zengqi Cui Ruirui Fan Changqing Feng Minhao Gu Fengqin Guo Changcai Han Zijie Han Guozhu He Yongcheng He Yuefeng He Hanxiong Huang Weiling Huang Xiru Huang Xiaolu Ji Xuyang Ji Haoyu Jiang Hantao Jing Ling Kang Mingtao Kang Bo Li Lun Li Qiang Li Xiao Li Yang Li Yang Li Rong Liu Shubin Liu Xingyan Liu Yinglin Ma Changjun Ning Binbin Qi Zhaohui Song Hong Sun Xiaoyang Sun Zhijia Sun Zhixin Tan Hongqing Tang Jingyu Tang Pengcheng Wang Qi Wang Taofeng Wang Yanfeng Wang Zhaohui Wang Zheng Wang Jie Wen Zhongwei Wen Qingbiao Wu Xiaoguang Wu Xuan Wu Likun Xie Yiwei Yang Han Yi Li Yu Tao Yu Yongji Yu Guohui Zhang Jing Zhang Linhao Zhang Liying Zhang Qingmin Zhang Qiwei Zhang Xianpeng Zhang Yuliang Zhang Zhiyong Zhang Yingtan Zhao Liang Zhou Zuying Zhou Danyang Zhu Kejun Zhu Peng Zhu | 2019 | Radiation Detection Technology and Methods2019，3，3： | 1 |
| 10 | Engineered gold/black phosphorus nanoplatforms with remodeling tumor microenvironment for sonoactivated catalytic tumor theranostics显示文摘The imbalance between oxidants and antioxidants in cancer cells would evoke oxidative stress-induced cell death,which has been demonstrated to be highly effective in treating malignant tumors.Sonodynamic therapy(SDT)adopts ultrasound(US)as the excitation source to induce the production of reactive oxygen species(ROS),which emerges as a noninvasive therapeutic strategy with deep tissue penetration depth and high clinical safety.Herein,we construct novel sonoactivated oxidative stress amplification nanoplatforms by coating MnO_(2) on Au nanoparticle-anchored black phosphorus nanosheets and decorating soybean phospholipid subsequently(Au/BP@MS).The Au/BP@MS exhibit increased ROS generation efficiency under US irradiation in tumor tissues due to Au/BP nanosensitizer-induced improvement of electron-hole separation as well as MnO_(2)-mediated O_(2) generation and GSH depletion,thus leading to notable inhibition effect on tumor growth.Moreover,tumor microenvironment-responsive biodegradability of Au/BP@MS endows them with enhanced magnetic resonance imaging guidance and clinical potential for cancer theranostics. | Ting Chen Weiwei Zeng Changjun Tie Mian Yu Huisong Hao Yang Deng Qianqian Li Hairong Zheng Meiying Wu Lin Mei | 2022 | Bioactive Materials2022，7，4： | 1 |
| 11 | Distribution patterns of plant communities and their associations with environmental soil factors on the eastern shore of Lake Taihu,China显示文摘Introduction:Plant communities and soil factors might interact with each other in different temporal and spatial scales,which can influence the patterns and processes of the wetland ecosystem.To get a better understanding of the distribution of plants in wetlands and analyze their associations with environmental soil factors,the structure and types of plant communities in the eastern shore area of Lake Taihu were analyzed by two-way indicator species analysis and canonical correspondence analysis(CCA)ordination.The spatial distribution patterns of vegetation and the main factors affecting the distributions were investigated.Outcomes:Sixty-six sampling sites were selected to obtain vegetation species and soil environmental factor data.Results showed that 22 species from the 66 sites could be divided into seven communities:I:Arundo donax;II:A.donax+Phragmites australis;III:Zizania latifolia+Typha orientalis;IV:P.australis+Alternanthera philoxeroides+Polygonum hydropiper;V:P.australis;VI:P.australis+Humulus scandens;and VII:Erigeron acer+Ipomoea batatas+Rumex acetosa.Plant species and soil factors in the CCA analysis showed that I.batatas,E.acer,Chenopodium album,Polygonum lapathifolium,and Acalypha australis were mainly affected by pH,whereas Echinochloa crus-galli,Setaria viridis,and H.scandens were mainly affected by soil total phosphorus.Mentha canadensis and A.donax were mainly affected by soil conductivity,A.philoxeroides was mainly affected by soil organic matter and,Z.latifolia,Metaplexis japonica and P.hydropiper were mainly affected by available phosphorus.Conclusion:These results indicated that different plants adapted to different soil environmental factors and provided basic information on the diversity of Lake Taihu wetland vegetation. | Wei Li Lijuan Cui Baodi Sun Xinsheng Zhao Changjun Gao Yan Zhang Manyin Zhang Xu Pan Yinru Lei Wu Ma | 2017 | Ecosystem Health and Sustainability2017，3，9： | 1 |
| 12 | Effect of reverse modification of Al-5Ti-B master alloy on hypoeutectic Zn Al4Y alloy显示文摘 | Wang Jianhua Huang Jianfeng Su Xuping Wu Changjun | 2012 | Materials and Design2012，，38： | 1 |
| 13 | Expression of endostatin mediated by a novel non-viral delivery system inhibits human umbilical vein endothelial cells in vitro显示文摘 | Chunmei Zhang Xueju Zhang Chunbo Liu Junfeng Wang Xinghan Liu Hulun Li Jinghua Wang Changjun Wu | 2010 | Molecular Biology Reports2010，，4： | 1 |
| 14 | Apoptotic effect of sonodynamic therapy mediated by hematoporphyrin monomethyl ether on C6 glioma cells in vitro显示文摘 | Shaochun Dai Shaoshan Hu Changjun Wu | 2009 | Acta Neurochirurgica2009，，12： | 1 |
| 15 | Apoptotic effect of sonodynamic therapy mediated by hematoporphyrin monomethyl ether on C6 glioma cells in vitro 显示文摘 | Dai Shaochun Hu Shaoshan Wu Changjun | 2009 | Acta Neurochirurgica2009，151，12： | 1 |
| 16 | Corrosion behaviors of Mg and its alloys with different Al contents in a modified simulated body fluid显示文摘 | Zhaohui Wen Changjun Wu Changsong Dai Feixia Yang | 2009 | Journal of Alloys and Compounds2009，，1： | 1 |
| 17 | A steady state sim-ulation method for natural gas pressure - relieving sys- tems 显示文摘 | Li Changjun Jia Wenlong Wu Xia | 2014 | Journal of Natural Gas Science and Engineer- ing2014，19，： | 1 |
| 18 | The Influence of Electrode on Resistivity of Conductive Asphalt Concrete for Self-monitoring显示文摘 | Changjun Sun Lijuan Qing Shaopeng Wu | 2012 | Key Engineering Materials2012，509，： | 1 |
| 19 | Selenium level surveillance for the year 2007 of Keshan disease in endemic areas and analysis on surveillance results between 2003 and 2007显示文摘 | YANG Jingyuan WANG Tong WU Changjun | 2010 | Biological Trace Element Research2010，138，1： | 1 |
| 20 | The fouling properties of SiO2-CaO-P2O5 system in high-temperature rotary kiln phosphoric acid process显示文摘Kiln phosphoric acid(KPA)technology could produce P2O5 with high purity and has been applied in thermal phosphoric acid industry;however the formation of fouling in the high-temperature rotary kiln restricts the stable and long-term operation.In this paper,the reaction of phosphate ores with gaseous P2O5 was investigated in a high-temperature reactor,and the Ca O-SiO2-P2O5 ternary phase diagram was analyzed to understand the fouling formation mechanism.The results showed that the low-melting-point products,such as Ca(PO3)2and Ca2P2O7,are responsible for the fouling in the KPA process.In addition,a small amount of impurities,e.g.,aluminum and iron,could facilitate the generation of the low-melting-point products and cause serious fouling.Based on the high-temperature SiO2-P2O5 and CaO-SiO2-P2O5 phase diagram analysis,the control of Si/Ca molar ratio(e.g.,Si/Ca=2.0)was found to avoid fouling formation in the kiln.These results could provide the operation parameters of reaction temperature and feeds composition to suppress the fouling in the kiln reactor for the phosphoric acid production in industry. | Pan Wu Li Lü Siyang Tang Changjun Liu Hairong Yue Wei Jiang Bin Liang | 2020 | Chinese Journal of Chemical Engineering2020，28，7： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员