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124篇 您的检索式:作者名="Li Changjun"
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1Laparoscopic Partial Nephrectomy With Segmental Renal Artery Clamping:Technique and Clinical Outcomes显示文摘Background:Warm ischemic injury is one of the most important factors affecting renal function in partial nephrectomy(PN).The technique of segmental renal artery clamping emerges as an alternative to conventional renal artery clamping for renal hilar control.Objective:To evaluate the feasibility and efficiency of laparoscopic PN(LPN) with segmental renal artery clamping in comparison with the conventional technique.Design,setting,and participants:A total of 75 patients underwent LPN from June 2007 to November 2009.All patients had T1a or T1b tumor in one kidney and a normal contralateral kidney.Thirty-seven patients underwent surgeries with main renal artery clamping,and 38 underwent surgeries with segmental artery clamping.Intervention:All procedures were performed by the same laparoscopic surgeon.Measurements:Blood loss,operation time,warm ischemia(WI) time,and complications affected renal function before and after operation were recorded.Results and limitations:All LPNs were completed without conversion to open surgery or nephrectomy.The novel technique slightly increased WI time(p < 0.001) and intraoperative blood loss(p = 0.006),while it provided better postoperative affected renal function(p < 0.001) compared with the conventional technique.The total complication rate was 12%.Among the 38 cases where segmental renal artery clamping was performed,7 had to convert to the conventional method.Tumor size and location influenced the number of clamped segmental arteries.Long-term postoperative renal function is still awaited.Conclusions:LPN with segmental artery clamping is safe and feasible in clinical practice.It minimizes the intraoperative WI injury and improves early postoperative affected renal function compared with main renal artery clamping.(C) 2010 European Association of Urology.Published by Elsevier B.V.All rights reserved.Shao,P.F. Qin,C. Yin,C.J. Meng,X.X. Ju,X.B. Li,J. Lü,Q.A. Zhang,W. Xu,Z.Q.Shao,Pengfei Qin,Chao Yin,Changjun Meng,Xiaoxin Ju,Xiaobing Li,Jie Lü,Qiang Zhang,Wei Xu,Zhengquan] Nanjing Med Univ,Affiliated Hosp 1,Dept Urol,Nanjing,Peoples R China.Guangzhou Rd 300,Nanjing 210029,Peoples R China. 2011南京医科大学学报(自然科学版)2011,31,7:123
2Massive individual orbital angular momentum channels for multiplexing enabled by Dammann gratings显示文摘Data transmission rates in optical communication systems are approaching the limits of conventional multiplexing methods.Orbital angular momentum(OAM)in optical vortex beams offers a new degree of freedom and the potential to increase the capacity of free-space optical communication systems,with OAM beams acting as information carriers for OAM division multiplexing(OAM-DM).We demonstrate independent collinear OAM channel generation,transmission and simultaneous detection using Dammann optical vortex gratings(DOVGs).We achieve 80/160 Tbit s^(-1) capacity with uniform power distributions along all channels,with 1600 individually modulated quadrature phase-shift keying(QPSK)/16-QAM data channels multiplexed by 10 OAM states,80 wavelengths and two polarizations.DOVG-enabled OAM multiplexing technology removes the bottleneck of massive OAM state parallel detection and offers an opportunity to raise optical communication systems capacity to Pbit s^(-1) level.Ting Lei Meng Zhang Yuru Li Ping Jia Gordon Ning Liu Xiaogeng Xu Zhaohui Li Changjun Min Jiao Lin Changyuan Yu Hanben Niu Xiaocong Yuan 2015Light(Science & Applications)2015,4,1:47
3Differences in microstructure and properties between selective laser melting and traditional manufacturing for fabrication of metal parts: A review显示文摘(直线波松) 作为生产技术的添加剂之一,选择激光融化广泛地被调查制作金属部分。在直线波松,部分以一种 layer-by-layer 方式从粉末直接被生产;直线波松也提供几个优点,例如有高三维的精确性的复杂部分的生产,与生产技术的另外的添加剂相比。因此,直线波松能在航空学被使用,航天学,药,并且死并且铸造工业。然而,这种技术不同于传统的方法,例如扔并且前进;例如,前者极大地以产品的微观结构和性质不同。这份报纸通过直线波松在金属材料制造上总结相关研究。基于在 Huazhong 大学 Sci 技术完成的一个工作,快速的 Manuf。中心(HUST-RMC ) 并且与在其它描述的特征相比,直线波松的报导研究,微观结构,性质,维的精确性,和应用被介绍。Bo SONG Xiao ZHAO Shuai LI Changjun HAN Qingsong WEI Shifeng WEN Jie LIU Yusheng SHI 2015Frontiers of Mechanical Engineering2015,10,2:26
4Current status of diagnosis and treatment of bladder cancer in China-Analyses of Chinese Bladder Cancer Consortium database显示文摘Objective:To investigate current status of diagnosis and treatment of bladder cancer in China.Methods:A database was generated by Chinese Bladder Cancer Consortium(CBCC).From January 2007 to December 2012,14,260 cases from 44 CBCC centers were included.Data of diagnosis,treatment and pathology were collected.Results:The average age was 63.5 year-old and most patients were male(84.3%).The most common histologic types were urothelial carcinoma(91.4%),adenocarcinoma(1.8%),and squamous carcinoma(1.9%).According to 1973 and 2004 WHO grading system,42.0%,41.0%,and 17.0% of patients were grade 1,2,and 3,and 16.0%,48.7%,and 35.3% of patients were papillary urothelial neoplasms of low malignant potential,low,and high grade,respectively.Non-muscle invasive bladder cancer(NMIBC)and muscle invasive bladder cancer(MIBC)were 25.2% and 74.1%,respectively(0.8% not clear).Carcinoma in situ was only 2.4%.Most patients were diagnosed by white-light cystoscopy with biopsy(74.3%).Fluorescence and narrow band imaging cystoscopy had additional detection rate of 1.0% and 4.0%,respectively.Diagnostic transurethral resection(TUR)provided detection rate of 16.9%.Most NMIBCs were treated with TUR(89.2%).After initial TUR,2.6%accepted second TUR,and 45.7%,69.9%,and 58.7% accepted immediate,induced,and maintenance chemotherapy instillation,respectively.Most MIBCs were treated with radical cystectomy(RC,59.7%).Laparoscopic RCs were 35.1%,while open RC 63.4%.Extended and standard pelvic lymph node dissection were 7% and 66%,respectively.Three most common urinary diversions were orthotopic neobladder(44%),ileal conduit(31%),and ureterocutaneostomy(23%).Only 2.3% of patients accepted neo-adjuvant chemotherapy and only 18%of T3 and T4 patients accepted adjuvant chemotherapy.Conclusion:Disease characteristics are similar to international reports,while differences of diagnosis and treatment exist.This study can provide evidences for revisions of the guideline on bladder cancer in China.Kaiwen Li Tianxin Lin Wei Xue Xin Mu Enci Xu Xu Yang Fubao Chen Guangyong Li Lulin Ma Guoliang Wang Chaozhao Liang Haoqiang Shi Ming Li Mao Tang Xueyi Xue Yisong Lv Yaoliang Deng Chengyang Li Zhiwen Chen Xiaozhou Zhou Fengshuo Jin Xudong Liu Jinxin Wei Lei Shi Xin Gou Weiyang He Liqun Zhou Lin Cai Baiye Jin Guanghou Fu Xiangbo Kong Hongyan Sun Ye Tian Lang Feng Tiejun Pan Yiyi Wu Dongwen Wang Hailong Hao Benkang Shi Yaofeng Zhu Qiang Wei Ping Han Changli Wu Dawei Tian Zhangqun Ye Zheng Liu Zhiping Wang Junqiang Tian Lin Qi Minfeng Chen Wei Li Jinchun Qi Gongxian Wang Longlong Fu Zhaolin Sun Guangheng Luo Zhoujun Shen Zhaowei Zhu Jinchun Xing Zhun Wu Dong Wei Xin Chen Yanqun Na Hongfeng Guo Chunxi Wang Zhihua Lu Chuize Kong Yang Liu Jin Yang Jianyun Hu Xin Gao Jielin Li Changjun Yin Pu Li Shan Chen Zhen Du Jiongming Li Yongji Yan Xu Zhang Shuang Huang Fangjian Zhou Zhiling Zhang Yinghao Sun Shuxiong Zeng Song Cen Jiaquan Zhou Hanzhong Li Jin Wen Jian Huang 2015Asian Journal of Urology2015,2,2:21
5Virus-induced gene silencing and its application in plant functional genomics显示文摘Virus-induced gene silencing is regarded as a powerful and efficient tool for the analysis of gene function in plants because it is simple, rapid and transformation-free. It has been used to perform both forward and reverse genetics to identify plant functional genes. Many viruses have been developed into virus-induced gene silencing vectors and gene functions involved in development, biotic and abiotic stresses, metabolism, and cellular signaling have been reported. In this review, we discuss the development and application of virus-induced gene silencing in plant functional genomics.HUANG ChangJun QIAN YaJuan LI ZhengHe ZHOU XuePing 2012Science China(Life Sciences)2012,55,2:20
6Endocrine role of bone in the regulation of energy metabolism显示文摘Bone mainly functions as a supportive framework for the whole body and is the major regulator of calcium homeostasis and hematopoietic function.Recently,an increasing number of studies have characterized the significance of bone as an endocrine organ,suggesting that bone-derived factors regulate local bone metabolism and metabolic functions.In addition,these factors can regulate global energy homeostasis by altering insulin sensitivity,feeding behavior,and adipocyte commitment.These findings may provide a new pathological mechanism for related metabolic diseases or be used in the diagnosis,treatment,and prevention of metabolic diseases such as osteoporosis,obesity,and diabetes mellitus.In this review,we summarize the regulatory effect of bone and bone-derived factors on energy metabolism and discuss directions for future research.Ruoyu Zhou Qiaoyue Guo Ye Xiao Qi Guo Yan Huang Changjun Li Xianghang Luo 2021Bone Research2021,9,4:11
7An efficient methodology for utilization of K-feldspar and phosphogypsum with reduced energy consumption and CO2 emissions显示文摘The issues of reducing CO_2 emissions, sustainably utilizing natural mineral resources, and dealing with industrial waste offer challenges for sustainable development in energy and the environment. We propose an efficient methodology via the co-reaction of K-feldspar and phosphogypsum for the extraction of soluble potassium salts and recovery of SO_2 with reduced CO_2 emission and energy consumption. The results of characterization and reactivity evaluation indicated that the partial melting of K-feldspar and phosphogypsum in the hightemperature co-reaction significantly facilitated the reduction of phosphogypsum to SO_2 and the exchange of K^+(K-feldspar) with Ca^(2+)(CaSO_4 in phosphogypsum). The reaction parameters were systematically investigated with the highest sulfur recovery ratio of ~ 60% and K extraction ratio of ~ 87.7%. This novel methodology possesses an energy consumption reduction of ~ 28% and CO_2 emission reduction of ~ 55% comparing with the present typical commercial technologies for utilization of K-feldspar and the treatment of phosphogypsum.Zhixi Gan Zheng Cui Hairong Yue Siyang Tang Changjun Liu Chun Li Bin Liang Heping Xie 2016Chinese Journal of Chemical Engineering2016,24,11:11
8Global Fine Registration of Point Cloud in LiDAR SLAM Based on Pose Graph显示文摘The laser scanning system based on Simultaneous Localization and Mapping(SLAM)technology has the advantages of low cost,high precision and high efficiency.It has drawn wide attention in the field of surveying and mapping in recent years.Although real-time data acquisition can be achieved using SLAM technology,the precision of the data can’t be ensured,and inconsistency exists in the acquired point cloud.In order to improve the precision of the point cloud obtained by this kind of system,this paper presents a hierarchical point cloud global optimization algorithm.Firstly,the“point-to-plane”iterative closest point(ICP)algorithm is used to match the overlapping point clouds to form constraints between the trajectories of the scanning system.Then a pose graph is constructed to optimize the trajectory.Finally,the optimized trajectory is used to refine the point cloud.The computational efficiency is improved by decomposing the optimization process into two levels,i.e.local level and global level.The experimental results show that the RMSE of the distance between the corresponding points in overlapping areas is reduced by about 50%after optimization,and the internal inconsistency is effectively eliminated.Li YAN Jicheng DAI Junxiang TAN Hua LIU Changjun CHEN 2020Journal of Geodesy and Geoinformation Science2020,3,2:9
9Experimental measurement of the electrical conductivity of single crystal olivine at high temperature and high pressure under different oxygen fugacities显示文摘At 1.0-4.0 GPa and 1123-1473 K and under oxygen fugacity-controlled conditions (Ni + NiO, Fe + Fe3O4, Fe + FeO and Mo+ M0O2 buffers), a YJ-3000t Model six-anvil solid high-pressure apparatus and a Sarltron-1260 Impedance/Gain-Phase analyzer were employed to conduct an in situ measurement of the electrical conductivity of single crystal olivine. Experimental results showed that: (1) within the range of experimentally selected frequencies (103-106 Hz), the electrical conductivity of the sample is of great dependence on the frequency; (2) with the rise of temperature ( T), the electrical conductivity (σ) will increase, and the Arrenhius linear relationship is established between lgσ and 1/T; (3) under the control of oxygen buffer Fe+ Fe3O4, with the rise of pressure, the electrical conductivity tends to decrease whereas the activation enthalpy and independent-of-temperature preexponential factor tend to increase, with the activation energy and activation volume of the sample estimated at (1. 25 ± 0.08) eV and (0.105 ±0.025) cm3/mol, respectively; (4) under given pressure and temperature conditions, the electrical conductivity tends to increase whereas the activation energy tends to decrease with increasing oxygen fugacity; and ( 5) the mechanism of electrical conduction of small polarons can provide insight into the behavior of electrical conduction of olivine under high pressure and high temperature.DAI Lidong LI Heping LIU Congqiang CUI Tongdi SHAN Shuangming YANG Changjun LIU Qingyou DENG Heming 2006Progress in Natural Science:Materials International2006,16,4:9
10Effect of total aluminum concentration on the formation and transformation of nanosized Al_(13) and Al_(30) in hydrolytic polymeric aluminum aqueous solutions显示文摘Influence of total aluminum concentration (CAlT) on the generation and transformation of nanosized Al13 and Al30 in hydrolytic polyaluminum aqueous solutions was in-vestigated using high field 27Al NMR and time-developed Al-Ferron complex colorimetry. When prepared at the opti-mal basicity (B) of Al13 generation and 80℃, the Al13 species in polyaluminum solution tends to further polymerize and convert to Al30 and higher polymers when CAlT >0.2 mol·L?1, but Al13 does not convert to Al30 quantificationally, as the formation of Alu from Al13 and Al30 is accelerated in the same way. The conversion rate of Al13 is accelerated by the in-crease in CAlT. When CAlT >0.75 mol·L?1, Al13 content de-creases rapidly, and Al30 content increases continuously and becomes the dominant nanometer polynuclear aluminum species. Alm is one of prerequisites of Al13 conversion to Al30. When CAlT increases and B reduces, the polymerization rate between Al13 and Alm increases, and at the same time, the dissociation reaction rate of Al13 and Al30 by H+ also increases. The latter becomes the dominant reaction in polyaluminum solution with low B value, so Al30 decreases with the increas-ing CAlT. The hydrolytic polyaluminum solution with Al13 content beyond 80% can only be prepared under the condi-tion of CAlT<0.5 mol·L?1 and optimal B value.CHEN Zhaoyang LIU Changjun LUAN Zhaokun ZHANG Zhongguo LI Yanzhong JIA Zhiping 2005Chinese Science Bulletin2005,50,18:8
11Ultra-broadband on-chip twisted light emitter for optical communications显示文摘On-chip twisted light emitters are essential components of orbital angular momentum(OAM)communication devices1,2.These devices address the growing demand for high-capacity communication systems by providing an additional degree of freedom for wavelength/frequency division multiplexing(WDM/FDM).Although whispering-gallery-mode-enabled OAM emitters have been shown to possess some advantages3–5,such as compactness and phase accuracy,their inherent narrow bandwidths prevent them from being compatible with WDM/FDM techniques.Here,we demonstrate an ultra-broadband multiplexed OAM emitter that utilizes a novel joint path-resonance phase control concept.The emitter has a micron-sized radius and nanometer-sized features.Coaxial OAM beams are emitted across the entire telecommunication band from 1,450 to 1,650 nm.We applied the emitter to an OAM communication with a data rate of 1.2 Tbit/s assisted by 30-channel optical frequency combs(OFCs).The emitter provides a new solution to further increase capacity in the OFC communication scenario.Zhenwei Xie Ting Lei Fan Li Haodong Qiu Zecen Zhang Hong Wang Changjun Min Luping Du Zhaohui Li Xiaocong Yuan 2018Light(Science & Applications)2018,7,1:7
12New innovations in pavement materials and engineering:A review on pavement engineering research 2021显示文摘Sustainable and resilient pavement infrastructure is critical for current economic and environmental challenges.In the past 10 years,the pavement infrastructure strongly supports the rapid development of the global social economy.New theories,new methods,new technologies and new materials related to pavement engineering are emerging.Deterioration of pavement infrastructure is a typical multi-physics problem.Because of actual coupled behaviors of traffic and environmental conditions,predictions of pavement service life become more and more complicated and require a deep knowledge of pavement material analysis.In order to summarize the current and determine the future research of pavement engineering,Journal of Traffic and Transportation Engineering(English Edition)has launched a review paper on the topic of'New innovations in pavement materials and engineering:A review on pavement engineering research 2021'.Based on the joint-effort of 43 scholars from 24 well-known universities in highway engineering,this review paper systematically analyzes the research status and future development direction of 5 major fields of pavement engineering in the world.The content includes asphalt binder performance and modeling,mixture performance and modeling of pavement materials,multi-scale mechanics,green and sustainable pavement,and intelligent pavement.Overall,this review paper is able to provide references and insights for researchers and engineers in the field of pavement engineering.JTTE Editorial Office Jiaqi Chen Hancheng Dan Yongjie Ding Yangming Gao Meng Guo Shuaicheng Guo Bingye Han Bin Hong Yue Hou Chichun Hu Jing Hu Ju Huyan Jiwang Jiang Wei Jiang Cheng Li Pengfei Liu Yu Liu Zhuangzhuang Liu Guoyang Lu Jian Ouyang Xin Qu Dongya Ren Chao Wang Chaohui Wang Dawei Wang Di Wang Hainian Wang Haopeng Wang Yue Xiao Chao Xing Huining Xu Yu Yan Xu Yang Lingyun You Zhanping You Bin Yu Huayang Yu Huanan Yu Henglong Zhang Jizhe Zhang Changhong Zhou Changjun Zhou Xingyi Zhu 2021Journal of Traffic and Transportation Engineering(English Edition)2021,8,6:7
13First light of the 1.8-m solar telescope–CLST显示文摘Large-aperture solar telescopes play an important role in solar observations and research,and require high temporal and spatial resolution[1].To solve some fundamental problems such as the solar dynamo,coronal heating,and the triggering of major solar eruptions,the spatial resolution for solar-atmosphere observation should reach at least 0.1 arcsec[2].ChangHui Rao NaiTing Gu XueJun Rao Cheng Li LanQiang Zhang JinLong Huang Lin Kong Ming Zhang YunTao Cheng Yi Pu Hua Bao YouMing Guo YangYi Liu JinSheng Yang LiBo Zhong ChangJun Wang Kai Fang XiaoJun Zhang DongHong Chen Cheng Wang XinLong Fan ZhiWu Yan KeLe Chen XiYa Wei Lei Zhu Hong Liu YongJian Wan Hao Xian WenLi Ma 2020Science China(Physics,Mechanics & Astronomy)2020,63,10:6
14The CO_2 absorption and desorption performance of the triethylenetetramine + N,N-diethylethanolamine + H_2O system显示文摘Post-combustion CO_2 capture(PCC) process faces significant challenge of high regeneration energy consumption.Biphasic absorbent is a promising alternative candidate which could significantly reduce the regeneration energy consumption because only the CO_2-concentrated phase should be regenerated. In this work, aqueous solutions of triethylenetetramine(TETA) and N,N-diethylethanolamine(DEEA) are found to be efficient biphasic absorbents of CO_2. The effects of the solvent composition, total amine concentration, and temperature on the absorption behavior, as well as the effect of temperature on the desorption behavior of TETA–DEEA–H2 O system were investigated. An aqueous solution of 1 mol·L-1 TETA and 4 mol·L-1 DEEA spontaneously separates into two liquid phases after a certain amount of CO_2 is absorbed and it shows high CO_2 absorption/desorption performance.About 99.4% of the absorbed CO_2 is found in the lower phase, which corresponds to a CO_2 absorption capacity of 3.44 mol·kg-1. The appropriate absorption and desorption temperatures are found to be 30 °C and 90 °C,respectively. The thermal analysis indicates that the heat of absorption of the 1 mol·L-1 TETA and 4 mol·L-1 DEEA solution is-84.38 kJ·(mol CO_2)-1 which is 6.92 kJ·(mol CO_2)-1 less than that of aqueous MEA. The reaction heat, sensible heat, and the vaporization heat of the TETA–DEEA–H2 O system are lower than that of the aqueous MEA, while its CO_2 capacity is higher. Thus the TETA–DEEA–H2 O system is potentially a better absorbent for the post-combustion CO_2 capture process.Yaoyao Li Changjun Liu Richard Parnas Yingying Liu Bin Liang Houfang Lu 2018Chinese Journal of Chemical Engineering2018,26,11:6
15LRP6 in mesenchymal stem cells is required for bone formation during bone growth and bone remodeling显示文摘Lipoprotein receptor-related protein 6(LRP6) plays a critical role in skeletal development and homeostasis in adults. However, the role of LRP6 in mesenchymal stem cells(MSCs), skeletal stem cells that give rise to osteoblastic lineage, is unknown. In this study, we generated mice lacking LRP6 expression specifically in nestin1MSCs by crossing nestin-Cre mice with LRP6floxmice and investigated the functional changes of bone marrow MSCs and skeletal alterations. Mice with LRP6 deletion in nestin1cells demonstrated reductions in body weight and body length at 1 and 3 months of age. Bone architecture measured by microCT(mCT) showed a significant reduction in bone mass in both trabecular and cortical bone of homozygous and heterozygous LRP6mutant mice. A dramatic reduction in the numbers of osteoblasts but much less significant reduction in the numbers of osteoclasts was observed in the mutant mice. Osterix1osteoprogenitors and osteocalcin1osteoblasts significantly reduced at the secondary spongiosa area, but only moderately decreased at the primary spongiosa area in mutant mice. Bone marrow MSCs from the mutant mice showed decreased colony forming, cell viability and cell proliferation. Thus, LRP6 in bone marrow MSCs is essential for their survival and proliferation, and therefore, is a key positive regulator for bone formation during skeletal growth and remodeling.Changjun Li Bart O Williams Xu Cao Mei Wan 2014Bone Research2014,2,1:6
16Characterization and potential diagnostic application of monoclonal antibodies specific to rabies virus显示文摘Objective:Rabies is invariably a fatal encephalomyelitis that is considered to be a serious public health problem.It is necessary to develop standard rabies virus diagnostic tools,especially for diagnosing the strains prevalent in China.Methods:Monoclonal antibodies(MAbs)specific to rabies virus were produced and characterized by enzyme linked immunosorbent assay(ELISA),isotyping,affinity assay,immunofluorescence assay(IFA),and immunocytochemistry.The MAb,whose affinity was higher for antigen,was used to establish an antigen captureELISA(AC-ELISA)detection system and test the efficiency by using clinical samples.Results:The heavy chain subclasses of two MAbs were all determined to be IgG2a.The 3C7 MAb showed stronger reactivity with rabies virus protein than the 2C5 MAb in an ELISA analysis,whereas the 3C7 MAb showed the highest affinity for antigen.IFA and immunocytochemistry results also indicated that the two MAbs could recognize rabies virus protein in its native form in cell samples.Data obtained using clinical samples showed that rabies virus could be detected by AC-ELISA detection system using the 3C7 MAb.Conclusion:It was potentially useful for the further development of highly sensitive,easily handled,and relatively rapid detection kits/tools for rabies surveillance in those areas where rabies is endemic,especially in China.Xinjian Liu Xiaomin Feng Qi Tang Zhongcan Wang Zhenning Qiu Yuhua Li Changjun Wang Zhenqing Feng Jin Zhu Xiaohong Guan 2010The Journal of Biomedical Research2010,24,5:5
17Radiofrequency ablation versus partial nephrectomy for the treatment of clinical stage 1 renal masses: a systematic review and meta-analysis显示文摘Wang Shangqian Qin Chao Peng Zhihang Cao Qiang Li Pu Shao Pengfei Ju Xiaobing Meng Xiaoxin Lu Qiang Li Jie Wang Meilin Zhang Zhengdong Gu Min Zhang Wei Yin Changjun 2014Chinese Medical Journal2014,,13:5
18Retrieve Sea Surface Salinity Using Principal Component Regression Model Based on SMOS Satellite Data显示文摘The sea surface salinity(SSS) is a key parameter in monitoring ocean states. Observing SSS can promote the understanding of global water cycle. This paper provides a new approach for retrieving sea surface salinity from Soil Moisture and Ocean Salinity(SMOS) satellite data. Based on the principal component regression(PCR) model, SSS can also be retrieved from the brightness temperature data of SMOS L2 measurements and Auxiliary data. 26 pair matchup data is used in model validation for the South China Sea(in the area of 4?–25?N, 105?–125?E). The RMSE value of PCR model retrieved SSS reaches 0.37 psu(practical salinity units) and the RMSE of SMOS SSS1 is 1.65 psu when compared with in-situ SSS. The corresponding Argo daily salinity data during April to June 2013 is also used in our validation with RMSE value 0.46 psu compared to 1.82 psu for daily averaged SMOS L2 products. This indicates that the PCR model is valid and may provide us with a good approach for retrieving SSS from SMOS satellite data.ZHAO Hong LI Changjun LI Hongping LV Kebo ZHAO Qinghui 2016Journal of Ocean University of China2016,15,3:5
19Endothelial PDGF-BB/PDGFR-βsignaling promotes osteoarthritis by enhancing angiogenesis-dependent abnormal subchondral bone formation显示文摘The mechanisms that coordinate the shift from joint homeostasis to osteoarthritis(OA)remain unknown.No pharmacological intervention can currently prevent the progression of osteoarthritis.Accumulating evidence has shown that subchondral bone deterioration is a primary trigger for overlying cartilage degeneration.We previously found that H-type vessels modulate aberrant subchondral bone formation during the pathogenesis of OA.However,the mechanism responsible for the elevation of H-type vessels in OA is still unclear.Here,we found that PDGFR-βexpression,predominantly in the CD31^(hi)Emcn^(hi) endothelium,was substantially elevated in subchondral bones from OA patients and rodent OA models.A mouse model of OA with deletion of PDGFR-βin endothelial cells(ECs)exhibited fewer H-type vessels,ameliorated subchondral bone deterioration and alleviated overlying cartilage degeneration.Endothelial PDGFR-βpromotes angiogenesis through the formation of the PDGFR-β/talin1/FAK complex.Notably,endothelium-specific inhibition of PDGFR-βby local injection of AAV9 in subchondral bone effectively attenuated the pathogenesis of OA compared with that of the vehicle-treated controls.Based on the results from this study,targeting PDGFR-βis a novel and promising approach for the prevention or early treatment of OA.Zhuang Cui Hangtian Wu Ye Xiao Ting Xu Junjie Jia Hancheng Lin Rongmin Lin Kun Chen Yihuang Lin Kaiqun Li Xiaohu Wu Changjun Li Bin Yu 2022Bone Research2022,10,4:4
20Automatic tuning of sparse matrix-vector multiplication on multicore clusters显示文摘To have good performance and scalability, parallel applications should be sophisticatedly optimized to exploit intra-node parallelism and reduce inter-node communication on multicore clusters. This paper investigates the automatic tuning of the sparse matrix-vector(Sp MV) multiplication kernel implemented in a partitioned global address space language, which supports a hybrid thread- and process-based communication layer for multicore systems. One-sided communication is used for inter-node data exchange, while intra-node communication uses a mix of process shared memory and multithreading. We develop performance models to facilitate selecting the best configuration of threads and processes hybridization as well as the best communication pattern for Sp MV. As a result, our tuned Sp MV in the hybrid runtime environment consumes less memory and reduces inter-node communication volume, without damaging the data locality. Experiments are conducted on 12 real sparse matrices. On 16-node Xeon and 8-node Opteron clusters, our tuned Sp MV kernel gets on average 1.4X and 1.5X improvement in performance over the well-optimized process-based message-passing implementation, respectively.LI ShiGang HU ChangJun ZHANG JunChao ZHANG YunQuan 2015Science China(Information Sciences)2015,58,9:3
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