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| 1 | Epidemiological characteristics of thyroid nodules and risk factors for malignant nodules: a retrospective study from 6 304 surgical cases显示文摘 | Huan Qin Wang Kun Lou Fuchen Zhang Li Huang Qingxian Han Yunfeng Sun Hancheng Zhu Lei Lin Peng Song Jun Liu Fuqiang Wang Qian Hou Weikai | 2014 | Chinese Medical Journal2014，，12： | 20 |
| 2 | Research progress in the estimation of the postmortem interval by Chinese forensic scholars显示文摘The determination of time since death or the postmortem interval(PMI)is one of the most important and frequently asked questions in forensic medicine.Medicolegal scholars and forensic pathologists around the world have studied the estimation of PMI extensively in the past,and many novel methods and advanced technologies have now been applied in the field.For several centuries,Chinese forensic examiners have also worked on the estimation of the PMI,and there are a large number of excellent studies published in Chinese rather than in English,and these are not easily accessible or known internationally.Therefore we have conducted a review of relevant studies published by Chinese forensic scholars in the last few decades.The scope of this review is to provide a concise summary of the current progress in the estimation of PMI by Chinese forensic researchers using molecular biology,spectroscopic technology,entomological methods,energy changes,thanatochemistry and other methods. | Chengzhi Li Qi Wang Yinming Zhang Hancheng Lin Ji Zhang Ping Huang Zhenyuan Wang | 2016 | Forensic Sciences Research2016，1，1： | 9 |
| 3 | Endothelial PDGF-BB/PDGFR-βsignaling promotes osteoarthritis by enhancing angiogenesis-dependent abnormal subchondral bone formation显示文摘The mechanisms that coordinate the shift from joint homeostasis to osteoarthritis(OA)remain unknown.No pharmacological intervention can currently prevent the progression of osteoarthritis.Accumulating evidence has shown that subchondral bone deterioration is a primary trigger for overlying cartilage degeneration.We previously found that H-type vessels modulate aberrant subchondral bone formation during the pathogenesis of OA.However,the mechanism responsible for the elevation of H-type vessels in OA is still unclear.Here,we found that PDGFR-βexpression,predominantly in the CD31^(hi)Emcn^(hi) endothelium,was substantially elevated in subchondral bones from OA patients and rodent OA models.A mouse model of OA with deletion of PDGFR-βin endothelial cells(ECs)exhibited fewer H-type vessels,ameliorated subchondral bone deterioration and alleviated overlying cartilage degeneration.Endothelial PDGFR-βpromotes angiogenesis through the formation of the PDGFR-β/talin1/FAK complex.Notably,endothelium-specific inhibition of PDGFR-βby local injection of AAV9 in subchondral bone effectively attenuated the pathogenesis of OA compared with that of the vehicle-treated controls.Based on the results from this study,targeting PDGFR-βis a novel and promising approach for the prevention or early treatment of OA. | Zhuang Cui Hangtian Wu Ye Xiao Ting Xu Junjie Jia Hancheng Lin Rongmin Lin Kun Chen Yihuang Lin Kaiqun Li Xiaohu Wu Changjun Li Bin Yu | 2022 | Bone Research2022，10，4： | 4 |
| 4 | High-performance distributed feedback quantum dot lasers with laterally coupled dielectric gratings显示文摘The combination of grating-based frequency-selective optical feedback mechanisms,such as distributed feedback(DFB)or distributed Bragg reflector(DBR)structures,with quantum dot(QD)gain materials is a main approach towards ultrahigh-performance semiconductor lasers for many key novel applications,as either stand-alone sources or on-chip sources in photonic integrated circuits.However,the fabrication of conventional buried Bragg grating structures on GaAs,GaAs/Si,GaSb,and other material platforms has been met with major material regrowth difficulties.We report a novel and universal approach of introducing laterally coupled dielectric Bragg gratings to semiconductor lasers that allows highly controllable,reliable,and strong coupling between the grating and the optical mode.We implement such a grating structure in a low-loss amorphous silicon material alongside GaAs lasers with InAs/GaAs QD gain layers.The resulting DFB laser arrays emit at pre-designed 0.8 THz local area network wavelength division multiplexing frequency intervals in the 1300 nm band with record performance parameters,including sidemode suppression ratios as high as 52.7 dB,continuous-wave output power of 26.6 mW(room temperature)and 6 mW(at 55℃),and ultralow relative intensity noise(RIN)of<-165 dB/Hz(2.5-20 GHz).The devices are also capable of isolator-free operating under very high external reflection levels of up to-12.3 dB while maintaining high spectral purity and ultralow RIN qualities.These results validate the novel laterally coupled dielectric grating as a technologically superior and potentially cost-effective approach for fabricating DFB and DBR lasers free of their semiconductor material constraints,which are thus universally applicable across different material platforms and wavelength bands. | ZHUOHUI YANG ZHENGQING DING LIN LIU HANCHENG ZHONG SHENG CAO XINZHONG ZHANG SHIZHE LIN XIAOYING HUANG HUADI DENG YING YU SIYUAN YU | 2022 | Photonics Research2022，10，5： | 3 |
| 5 | Estimation of the age of human semen stains by attenuated total reflection Fourier transform infrared spectroscopy:a preliminary study显示文摘Semen stain is one of the most important biological evidence at sexual crime scenes.Age estimation of human semen stains plays an important role in forensic work,and it is rarely studied due to lack of well-established methods.In this study,the technique called attenuated total reflection Fourier transform infrared spectroscopy(ATR-FTIR)coupled with advanced chemometric methods was employed to determine the age of semen stains on three different substrates:glass slides,tissues and fabric made of regenerated cellulose fibres up to 6 d.Partial least squares regression(PLSR)was used in conjunction with spectral analysis for age estimation,and the results generated high R2 values(cross-validation:0.81,external validation:0.74)but a narrow margin of error for root mean square error(RMSE)(RMSE of cross-validation:0.77 d,RMSE of prediction:1.02 d).Additionally,our results indicated the robustness of PLSR model was not weaken by the influence of different substrates in this study.Our results indicate that ATR-FTIR,combined with chemometric methods,shows great potential as a convenient and efficient tool for age estimation of semen stains.Moreover,the method could be applied to routine forensic investigations in the future. | Shuai Zha Xin Wei Ruoxi Fang Qi Wang Hancheng Lin Kai Zhang Haohui Zhang Ruina Liu Zhouru Li Ping Huang Zhenyuan Wang | 2020 | Forensic Sciences Research2020，5，2： | 2 |
| 6 | The impacts of economic restructuring and technology upgrade on air quality and human health in Beijing-Tianjin-Hebei region in China显示文摘In this study, we have analyzed possible policy options to improve the air quality in an industrialized region—Beijing, Tianjin and Hebei (BTH) in China. A comprehensive model framework integrating GAINS-China, GEOS-Chem, and IMED/HEL is established to investigate the impacts of various policies on air pollution and health effects. The model establishes a data interface between economic input/output data and the emission inventory of atmospheric pollutants in the BTH region. Based on in-depth analyses of pollutant emission standards, industrial structure, pollution-intensive industries, and emission intensities in BTH and Pearl River Delta, several scenarios are constructed to explore the effectiveness of policy pathways in improving air quality in the BTH region. These scenarios include two categories: the category of “Industrial Technology Upgrade Policy” scenarios that focuses on reducing the emission intensity of industries vs. that of “Industrial Structure Adjustment Policy” scenarios that focuses on adjusting the proportion of industrial value-added. Our results show that the policy path of industrial technology upgrading can be effective and feasible, while economic structure adjustment shows complex and mixed effectiveness. We also find that the proposed policies and measures will be efficient to reduce pollution of primary pollutants and fine particles, but may not effectively mitigate ambient ozone pollution. Ozone pollution is projected to become increasingly severe in BTH, placing a challenge to pollution mitigation strategies that requires further adjustments to address it. | Chao Liu Hancheng Dai Lin Zhang Changchun Feng | 2019 | Frontiers of Environmental Science & Engineering2019，13，5： | 1 |
| 7 | Synergetic roadmap of carbon neutrality and clean air for China显示文摘It is well recognized that carbon dioxide and air pollutants share similar emission sources so that synergetic policies on climate change mitigation and air pollution control can lead to remarkable co-benefits on greenhouse gas reduction,air quality improvement,and improved health.In the context of carbon peak,carbon neutrality,and clean air policies,this perspective tracks and analyzes the process of the synergetic governance of air pollution and climate change in China by developing and monitoring 18 indicators.The 18 indicators cover the following five aspects:air pollution and associated weather-climate conditions,progress in structural transition,sources,inks,and mitigation pathway of atmospheric composition,health impacts and benefits of coordinated control,and synergetic governance system and practices.By tracking the progress in each indicator,this perspective presents the major accomplishment of coordinated control,identifies the emerging challenges toward the synergetic governance,and provides policy recommendations for designing a synergetic roadmap of Carbon Neutrality and Clean Air for China. | Qiang Zhang Zhicong Yin Xi Lu Jicheng Gong Yu Lei Bofeng Cai Cilan Cai Qimin Chai Huopo Chen Hancheng Dai Zhanfeng Dong Guannan Geng Dabo Guan Jianlin Hu Cunrui Huang Jianing Kang Tiantian Li Wei Li Yongsheng Lin Jun Liu Xin Liu Zhu Liu Jinghui Ma Guofeng Shen Dan Tong Xuhui Wang Xuying Wang Zhili Wang Yang Xie Honglei Xu Tao Xue Bing Zhang Da Zhang Shaohui Zhang Shaojun Zhang Xian Zhang Bo Zheng Yixuan Zheng Tong Zhu Jinnan Wang Kebin He | 2023 | Environmental Science and Ecotechnology2023，，4： | 0 |
| 8 | Skeleton Keypoints Extraction Method Combined with Object Detection显示文摘Big data is a comprehensive result of the development of the Internet of Things and information systems.Computer vision requires a lot of data as the basis for research.Because skeleton data can adapt well to dynamic environment and complex background,it is used in action recognition tasks.In recent years,skeleton-based action recognition has received more and more attention in the field of computer vision.Therefore,the keypoints of human skeletons are essential for describing the pose estimation of human and predicting the action recognition of the human.This paper proposes a skeleton point extraction method combined with object detection,which can focus on the extraction of skeleton keypoints.After a large number of experiments,our model can be combined with object detection for skeleton points extraction,and the detection efficiency is improved. | Jiabao Shi Zhao Qiu Tao Chen Jiale Lin Hancheng Huang Yunlong He d Yu Yang | 2022 | Journal of New Media2022，4，2： | 0 |
| 9 | A Image Copyright Protection Method Using Zero-Watermark by Blockchain and IPFS显示文摘Behind the popularity of multimedia technology,the dispute over image copyright is getting worse.In the digital watermark prevention technology for copyright infringement,watermark technology is considered to be an important technology to overcome data protection problems and verify the relationship between data ownership.Among the many digital watermarking technologies,zero watermarking technology has been favored in recent years.However,the existing zero watermark technology in the implementation process often needs a trusted third party to store watermarks,which may make the data too central,data storage security is low and copyright registration costs are too high,which creates a rare problem.The decentivization and information cannot be tampered of blockchain technology’s nature find new methods for image copyright protection.This paper studies the role of zero watermark algorithm in the image copyright and its complete storage and certification scheme,proposes a zero watermark image protection framework based on blockchain,and builds a system according to the framework.Combined with blockchain and zero watermarking technology,the framework uses inter IPFS(Inter Planetary File System)to solve the problem of blockchain efficient storage and sharing of large files.In addition,the application of user copyright information,image image query and image trading in the system are realized based on smart contracts,which solves the problem of lack of trusted third parties.Experiments show that the scheme is feasible and robust to various attacks. | Tao Chen Zhao Qiu Gengquan Xie Lin Yuan Shaohua Duan Hao Guo Dahao Fu Hancheng Huang | 2021 | Journal of Information Hiding and Privacy Protection2021，3，3： | 0 |
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