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| 1 | Preventive effect of glutamine on intestinal barrier dysfunction induced by severe trauma显示文摘AIM: To investigate the mechanism underlying intestinalbarrier function damage after severe trauma and thetherapeutic effect of glutamine.METHODS: Burned patients, and animal models of severstrauma replicated by hemorrhagic shock combined withendotoxin infusion and burn injury, were included in a serialexperiment. Effects of oral glutamine on intestinal barrierfunction were observed in scalded rets. Parametersmeasured in these experiments were as follows: plasmalevels of diamine oxidase (DAO), tumor necrosis factor(TNFα), endotoxin (LPS), and lactate as well as D-lactateby biochemical methods, lactose/mannitol (L/M) ratio inurine by SP-3400, and pathological examination of intestinalmucosa under light microscopy.RESULTS: Plasma DAO activity was significantly increasedafter injury. There was a negative correlation betweenplasma DAO and intestinal mucosal DAO or pHi ( r= -0.93,plasma 0.80 ± 0.93,2.83 ± 1.71, 1.14 ± 0.64,2.36 ± 2.06 and2.49± 1.67 vs intestinal 0.52± 0.12,0.34 ± 0.03,0.45 ± 0.18,0.37± 0.26 and 0.41 ± 0.07; r = - 0.533, plasma 0.87 ± 0.75,1.89± 1.13, 1.21 ± 0.23,3.03 ± 2.61 and 4.70 ± 1.22 Vs pHi7.03± 0.05,7.05 ± 0.06,7.14 ± 0.096,7.20 ± 0.08 and 7.05 ±0.07; P < 0.01-0.05). Positive correlations were foundbetween DAO activity and plasma TNFα, LPS, lactate, L/Mand D-lactate ( r = 0.817, 0.842, 0.872, and 0.951; plasmaDAO 0.87 ± 0.75,1.89 ± 1.13, 1.21 ± 0.23,3.03 ± 2.61 and 4.70± 1.22 vs TNF 0.08 ± 0.02,0.03 ± 0.25,0.17 ± 0.09,0.34 ± 0.15and 0.33 ± 0.18; vs LPS 0.14 ± 0.03,0.16 ± 0.04,0.21 ± 0.02,0.18± 0.16 and 0.37 ± 0.10; vs lactate 9.03 ± 2.19, 18.30 ±2.56,9.81 ± 2.83,12.01 ± 6.83, 12.01 ± 6.84 and 43.61 ± 11.27;vs L/M 0.03 ± 0.01,0.41 ± 0.27,0.62 ± 0.20, 1.70 ± 0.60; r =0.774, plasma DAO 1.25 ± 0.41,2.17 ± 0.71,2.29 ± 0.87, 1.23± 0.55 and 1.11 ± 0.47 vs D-lactate 8.37 ± 2.48, 18.25 ± 6.18,13.96 ± 4.94, 8.93 ± 3.00 and 12.39 ± 4.94; all P < 0.01),repestively. Damage of intestinal mucosa was found bypathological examination. Intestinal barrier function wasimproved to a certain extent by oral glutamine in scaldedrats.CONCLUSION: Intestinal barrier function was damaged in theearly stage after trauma. Plasma DAO activity, D-lactatecontent, intestinal pHi and urine L/M may be sensitivemarkers of intestinal mechanical injury, and glutamine mayprotect against intestinal barrier dysfunction after severetrauma. | Jun-You Li Yi Lu Sen Hu Dan Sun Yong-Ming Yao Burn Institute,Chinese PLA 304 Hospital,Beijing 100037,China | 2002 | World Journal of Gastroenterology2002，8，1： | 74 |
| 2 | Effect of wet flue gas desulfurization(WFGD) on fine particle(PM_(2.5)) emission from coal-fired boilers显示文摘In this study, the characteristics of fine particles before and after wet flue gas desulfurization(WFGD) in three coal-fired heating boilers in northern China were investigated by using a dilution-based emission sampling experimental system. The influences of the WFGD process on the mass and number concentrations as well as the chemical composition of fine particles were analyzed. The removal efficiency of desulfurization processes on particulate matter mass was 30.06%–56.25% for the three study units. The WFGD had a great influence on the size distributions of particle mass concentration and number concentration. A significant increase in the number and mass concentration of particles in the size range of 0.094–0.946 μm was observed. The watersoluble ion content accounted for a very large proportion of PM_(2.5) mass, and its proportion in PM_(2.5) increased from 28.39%–41.08% to 48.96%–61.21% after the WFGD process for the three units. The desulfurizing process also drastically increased the proportion of cation component(Ca^(2+) for unit A, Mg^(2+) for unit B, and Na+for unit C) and the proportion of SO_4^(2-) in PM_(2.5), and it increased the CE/AE values of PM_(2.5) from 0.82–0.98 to 0.93–1.27 for the three study units. | Sen Yao Shuiyuan Cheng Jianbing Li Hanyu Zhang Jia Jia Xiaowei Sun | 2019 | Journal of Environmental Sciences2019，31，3： | 8 |
| 3 | Fuzzy Consistent Matrix and Its Application显示文摘FuzzyConsistentMatrixandItsApplicationYaoMin&ZhangSenDept.ofComputerScience,HangzhouUniversity,310028,P.R.China(ReceivedSepte... | Yao, Min Zhang, Sen | 1997 | Journal of Systems Engineering and Electronics1997，8，1： | 8 |
| 4 | Expression analysis of ETS1 gene in peripheral blood mononuclear cells with systemic lupus erythematosus by real-time reverse transcription PCR显示文摘 | Li Yun Sun Liang-dan Lu Wen-sheng Hu Wen-long Gao Jin-ping Cheng Yi-lin Yu Ze-ying Yao Sha He Cai-feng Liu Jian-lan Cui Yong Yang Sen | 2010 | Chinese Medical Journal2010，，16： | 8 |
| 5 | Fluorite deposits in China:Geological features,metallogenic regularity,and research progress显示文摘Fluorite is one of the important mineral raw materials in the industry.In China,it is mainly distributed in the provinces and regions such as Hunan,Zhejiang,Jiangxi,Inner Mongolia,Fujian,and Henan provinces,boasting huge reserves and large numbers of deposits.However,most of the fluorite deposits are on a small or medium scale.The main fluorite deposits in China were studied in this paper.Their geological features and metallogenic regularity were summarized and compared.Meanwhile,based on their main genetic factors including metallogenic fluid sources and main metallogenic geological processes,they were divided into two groups,namely meso-epithermal deposits and magmatic-hydrothermal deposits.Furthermore,based on the prospecting achievements and research progress obtained in fluorite deposits in recent years,prospecting potential predictions were made for the metallogenic prospect areas and major prospecting areas of fluorite in China.This aims to provide a theoretical basis and direction for future fluorite prospecting in China. | Bei-bei Han Peng-qiang Shang Yong-zhang Gao Sen Jiao Chao-mei Yao Hao Zou Min Li Liang Wang Hou-yi Zheng | 2020 | China Geology2020，3，3： | 7 |
| 6 | Zn–Ca–Al mixed oxide as efficient catalyst for synthesis of propylene carbonate from urea and 1,2-propylene glycol显示文摘A series of Zn–Ca–Al oxides with different CaO and ZnO contents have been prepared and evaluated in the synthesis of propylene carbonate(PC) from 1,2-propylene glycol(PG) and urea in a batch reactor. The effect of catalyst composition, basicity and reaction process parameters such as temperature, catalyst dose, molar ratio of PG to urea, purge gas flow and reaction time has been studied to find suitable reaction conditions for the PC synthesis. The PC selectivity and yield under the desired conditions could reach 98.4% and 90.8%, respectively. The best performing catalyst also exhibited a good reusability without appreciable loss in the PC selectivity and yield after five consecutive reaction runs. In addition, a stepwise reaction pathway involving a 2-hydroxypropyl carbamate intermediate was proposed for the urea alcoholysis to PC in the presence of Zn–Ca–Al catalysts, according to the time dependences of reaction intermediates and products. | Sen Liu Suhong Sun Xuehui Tian Peiyong Sun Shenghong Zhang Zhilong Yao | 2017 | Chinese Journal of Chemical Engineering2017，25，5： | 4 |
| 7 | Aeolian Facies Belts in the Taklimakan Desert显示文摘At least at the beginning of the last glacial epoch, the facies belts of dune sand, sandy loam and loess formed by winds had existed in the Taklimakan desert and areas south of it. There were no appreciable changes in the NE and NW wind systems and their wind fqrces that deposited dune sand, sandy loam and loess in the global cold stage since the last glacial epoch (accordingly no marked shifts of the boundaries of these aeolian facies belts took place. In the global warm stage since then, the climate in the Taklimakan desert and areas south of it became warm and dry, resulting in ablation of substantial volumes of ice and snow in their surrounding mountains and thus forming alluvial and diluvial deposits in the region. The alluvial-diluvial actions, however, failed to change the general framework of aeolian facies belts. | Li Baosheng, Dong Guangrong, Zhang Jiasheng, Li Sen,Jin Heling, Chen Huizhong, Wen Xiangle, Wang Yao, Lanzhou Desert Research Institute, Chinese Academy of Sciences, Lamhou, Gansuand Zhu YizhiXi’an Open Laboratory of Loess and Quaternary Geology, Chinese Academy of Sciences, Xi’an, Gansu Fei Zhenbi | 1995 | Acta Geologica Sinica(English Edition)1995，69，3： | 4 |
| 8 | Air-stability of sodium-based layered-oxide cathode materials显示文摘Sodium-ion batteries have the potential to be an alternative to lithium-ion batteries especially for applications such as large-scale grid energy storage. The development of suitable cathode materials is crucial to the commercialization of sodium-ion batteries.Sodium-based layered-type transition metal oxides are promising candidates as cathode materials as they offer decent energy density and are easy to be synthesized. Unfortunately, most layered oxides suffer from poor air-stability, which greatly increases the cost of manufacturing and handling. The air-sensitivity severely limits the development and commercial application of sodium-ion batteries. A review that summarizes the latest understanding and solutions of air-sensitivity is desired. In this review,the background and fundamentals of sodium-based layered-type cathode materials are presented, followed by a discussion on the latest research on air-sensitivity of these materials. The mechanism is complex and involves multiple chemical and physical reactions. Various strategies are shown to alleviate some of the corresponding problems and promote the feasible application of sodium-ion batteries, followed by an outlook on current and future research directions of air-stable cathode materials. It is believed that this review will provide insights for researchers to develop practically relevant materials for sodium-ion batteries. | Hu-Rong Yao Lituo Zheng Sen Xin Yu-Guo Guo | 2022 | Science China Chemistry2022，65，6： | 3 |
| 9 | Novel magnetic silk fibroin scaffolds with delayed degradation for potential long-distance vascular repair显示文摘Although with the good biological properties,silk fibroin(SF)is immensely restrained in long-distance vascular defect repair due to its relatively fast degradation and inferior mechanical properties.It is necessary to construct a multifunctional composite scaffold based on SF.In this study,a novel magnetic SF scaffold(MSFCs)was prepared by an improved infiltration method.Compared with SF scaffold(SFC),MSFCs were found to have better crystallinity,magnetocaloric properties,and mechanical strength,which was ascribed to the rational introduction of iron-based magnetic nanoparticles(MNPs).Moreover,in vivo and in vitro experiments demonstrated that the degradation of MSFCs was significantly extended.The mechanism of delayed degradation was correlated with the dual effect that was the newly formed hydrogen bonds between SFC and MNPs and the complexing to tyrosine(Try)to inhibit hydrolase by internal iron atoms.Besides,theβ-crystallization of protein in MSFCs was increased with the rise of iron concentration,proving the beneficial effect after MNPS doped.Furthermore,although macrophages could phagocytose the released MNPs,it did not affect their function,and even a reasonable level might cause some cytokines to be upregulated.Finally,in vitro and in vivo studies demonstrated that MSFCs showed excellent biocompatibility and the growth promotion effect on CD34-labeled vascular endothelial cells(VECs).In conclusion,we confirm that the doping of MNPs can significantly reduce the degradation of SFC and thus provide an innovative perspective of multifunctional biocomposites for tissue engineering. | Xin Liu Yuxiang Sun Bo Chen Yan Li Peng Zhu Peng Wang Sen Yan Yao Li Fang Yang Ning Gu | 2022 | Bioactive Materials2022，7，1： | 3 |
| 10 | Antioxidant Effects of Oats Avenanthramides on Human Serum显示文摘The antioxidant ability of capsules containing oats avenanthramides on human body was evaluated in present study.Healthy people were randomized to supplementation with oats-derived avenanthramides capsules or placebo for 1 mon.Plasma lipid peroxides and antioxidant status were measured.For 8 capsules (containing 3.12 mg avenanthramides) groups,the levels of serum superoxide dismutase (SOD) and reduced glutathione hormone (GSH) were significantly increased by 8.4 and 17.9%,respectively (P<0.05),and malondialdehyde (MDA) level significantly decreased by 28.1%.The total cholesterol (TC),triglyceride (TG),and low density lipoprotein cholesterol (LDL-C) levels were lowered by 11.1,28.1,and 15.1%,respectively (P<0.05).The high density blood lipoprotein cholesterol (HDL-C) levels in the same treat was increased by 13.2%.Based on our research,it can be concluded that oats extract containing avenanthramides possessed a high antioxidative activity on humans.It indicated that oat avenanthramides could be used to prevent hyperlipemic and angiocardiopathy. | LIU Sen YANG Nan HOU Zhao-hua YAO Yang Lü Li ZHOU Xian-rong REN Gui-xing | 2011 | Agricultural Sciences in China2011，10，8： | 3 |
| 11 | Projections from D2 Neurons in Different Subregions of Nucleus Accumbens Shell to Ventral Pallidum Play Distinct Roles in Reward and Aversion显示文摘The nucleus accumbens shell(NAcSh) plays an important role in reward and aversion. Traditionally, NAc dopamine receptor 2-expressing(D2) neurons are assumed to function in aversion. However, this has been challenged by recent reports which attribute positive motivational roles to D2 neurons. Using optogenetics and multiple behavioral tasks, we found that activation of D2 neurons in the dorsomedial NAcSh drives preference and increases the motivation for rewards, whereas activation of ventral NAcSh D2 neurons induces aversion. Stimulation of D2 neurons in the ventromedial NAcSh increases movement speed and stimulation of D2 neurons in the ventrolateral NAc Sh decreases movement speed. Combining retrograde tracing and in situ hybridization, we demonstrated that glutamatergic and GABAergic neurons in the ventral pallidum receive inputs differentially from the dorsomedial and ventral NAcSh. All together, these findings shed light on the controversy regarding the function of NAcSh D2 neurons, and provide new insights into understanding the heterogeneity of the NAcSh. | Yun Yao Ge Gao Kai Liu Xin Shi Mingxiu Cheng Yan Xiong Sen Song | 2021 | Neuroscience Bulletin2021，37，5： | 3 |
| 12 | Plate-like carbon-supported Fe_(3)C nanoparticles with superior electrochemical performance显示文摘Iron-based anodes for lithium-ion batteries(LIBs)with higher theoretical capacity,natural abundance and cheapness have received considerable attention,but they still suffer from the fast capacity fading.To address this issue,we report a facile synthesis of plate-like carbonsupported Fe_(3)C nanoparticles through chemical blowing/carbonization under calcination.The ultrafine Fe_(3)C nanoparticles are prone to be oxidized when exposing in air;thus,Fe_(3)C/C with mild oxidization and the fully oxidized product of Fe_(2)O_(3)/C are successfully prepared by controlling the oxidization condition.When applied as an anode material in LIB,the Fe_(3)C/C electrode demonstrates excellent cycle stability(826 mAh·g^(-1)after 120 cycles under 500 mA·g^(-1))and rate performance(410.6 mAh·g^(-1) under 2 A·g^(-1)),compared with the Fe_(2)O_(3)/C counterpart.The enhanced electrochemical performance can be ascribed to the synergetic effect of the Fe_(3)C with mild oxidation and the unique hierarchical structure of plate-like carbon decorated with Fe_(3)C catalyst.More importantly,this work may offer new approaches to synthesize other transition metal(e.g.,Co,Ni)-based anode material by replacing the precursor ingredient. | Chuan Chen Sen Qian Tian-Hao Yao Jing-Hong Guo Hong-Kang Wang | 2021 | Rare Metals2021，40，6： | 2 |
| 13 | The Influence of Zusanli and Nonmeridian Acupuncture Points on the Survival Rate and Intestinal Tissue Features after Fatal Hemorrhagic Shock in Rats显示文摘 | Xian Shi Yuxian Zhong Jiarui Yao Sen Hu Lu Wang Gerhard Litscher Weibo Zhang | 2013 | Evidence-Based Complementary and Alternative Medicine2013，，： | 2 |
| 14 | Research of Impact Compaction Technology on Foundation and Subgrade in Yellow River Flooded Area显示文摘 | Zhang Kai Yao Zhan Yong Shang Qing Sen Song Xiu Guang | 2012 | Advanced Materials Research2012，，368： | 1 |
| 15 | Contribution of MDR1 gene polymorphisms on IBD predisposition and response to glucocorticoids in IBD in a C hinese population显示文摘 | Qing Fan Yang Bai Li Chen Qing Sen Zhang Zhen Hua Zhu Bin Hu Yao He Xiang Gao Yi Ming Wang Pin Jin Hu Min Hu Chen Zhi Rong Zeng | 2015 | Journal of Digestive Diseases2015，，1： | 1 |
| 16 | EIF4E over-expresses and enhances cell proliferation and cell cycle progression in nasopharyngeal carcinoma显示文摘 | Mengyan Wu Yingxia Liu Xiaoqing Di Haixian Kang Hua Zeng Yi Zhao Kangrong Cai Tianyun Pang Sen Wang Yunhong Yao Xinrong Hu | 2013 | Medical Oncology2013，，1： | 1 |
| 17 | On--line training adaptive neural network Controller 显示文摘 | Yao Zhang Pratyush Sen Grant E Hearn | 1995 | IEEE Control systems Magazine1995，，15： | 1 |
| 18 | Hearn, An On - line Trained Adaptive Neural Controller显示文摘 | Yao Zhang Pratyush Sen and Grant E | 1995 | IEEE Control Systems1995，74，10： | 1 |
| 19 | Instability of parasitic capacitance in T-shape-gate enhancementmode AlGaN/GaN MIS-HEMTs显示文摘Parasitic capacitances associated with overhangs of the T-shape-gate enhancement-mode(E-mode)GaN-based power device,were investigated by frequency/voltage-dependent capacitance-voltage and inductive-load switching measurements.The overhang capacitances induce a pinch-off voltage distinguished from that of the E-mode channel capacitance in the gate capacitance and the gatedrain capacitance characteristic curves.Frequency-and voltage-dependent tests confirm the instability caused by the trapping of interface/bulk states in the LPCVD-SiNx passivation dielectric.Circuit-level double pulse measurement also reveals its impact on switching transition for power switching applications. | Lan Bi Yixu Yao Qimeng Jiang Sen Huang Xinhua Wang Hao Jin Xinyue Dai Zhengyuan Xu Jie Fan Haibo Yin Ke Wei Xinyu Liu | 2022 | Journal of Semiconductors2022，43，3： | 1 |
| 20 | Next generation sequencing of pancreatic cyst fluid microRNAs from low grade-benign and high grade-invasive lesions显示文摘 | Jin Wang Pamela L. Paris Jinyun Chen Vy Ngo Hui Yao Marsha L. Frazier Ann M. Killary Chang-Gong Liu Han Liang Christian Mathy Sandhya Bondada Kimberly Kirkwood Subrata Sen | 2014 | Cancer Letters2014，，： | 1 |
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