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166篇 您的检索式:作者名="Schunkert"
    题名 作者 年代 出处 被引量
1胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 2017中华高血压杂志2017,25,9:2
2Development of heart failure following isoprotemeol administration in the rat : role of the reninangiotensin system 显示文摘Grimm D Eisner D Schunkert H Pfeifer M Griese D Bruekschleqel G 1998Cardiovase Res1998,37,:1
3Alteration of growth responses in established cardiac pressure overload hypertrophy in rats with aortic banding显示文摘Schunkert H Weinberg E O Bruckschlegel G 1995J Clin Invest1995,96,6:1
4Controversial association of left ventricular hypertrophy and the ACE I/D polymorphism is the mist clearing up?显示文摘Schunkert H 1999Nephrol Dial Transplant1999,13,:1
5Effects of hormone replacement therapies on fibrinogen and plasma viscosity in postmenopausal women显示文摘Frohlich M Schunkert H Hense HW 1998Br J Haematol1998,100,3:1
6Association between a deletion polymorphism of the angiotensin-converting-enzyme gene and left ventricular hypertrophy显示文摘Schunkert H Hense HW Holmer SR 1994N Engl J Med1994,330,23:1
7Large-seale associa- tion analysis identifies 13 new susceptibility loci for coronary artery disease显示文摘Schunkert H Konig IR Kathiresan S 2011Nat Genet2011,43,4:1
8Lack of Association Between the MEF2A Gene and Myocardial Infarction显示文摘Wolfgang Lieb Bj?rn Mayer Inke R. K?nig Iris Borwitzky Anika G?tz Silke Kain Christian Hengstenberg Patrick Linsel-Nitschke Marcus Fischer Angela D?ring H -Erich Wichmann Thomas Meitinger Reinhold Kreutz Andreas Ziegler Heribert Schunkert Jeanette Erdmann 2008Circulation2008,,2:1
9Microvascular obstruction in patients with non-ST-elevation myocardial infarction: a contrast-enhanced cardiac magnetic resonance study显示文摘Elena Guerra Martin Hadamitzky Gjin Ndrepepa Corinna Bauer Tareq Ibrahim Ilka Ott Karl-Ludwig Laugwitz Heribert Schunkert Adnan Kastrati 2014The International Journal of Cardiovascular Imaging2014,,:1
10Role of apoptosis in myocardial stunning after open heart surgery显示文摘Schmitt JP Schroder J Schunkert H 2002Ann Thorac Surg2002,73,4:1
11Genetics and heritability of coronary artery disease and myocardial infarction显示文摘Dr. Bj?rn Mayer MD Jeanette Erdmann PhD Heribert Schunkert MD 2007Clinical Research in Cardiology2007,,1:1
12Increased rat cardiac angiotensin converting enzyme activity and mRNA expression in pressure overload left ventricular hypertrophy:effects on coronary resistance,contractility,and relaxation显示文摘SCHUNKERT H DZAU V J TANG S S 1990J Clin Invest1990,86,6:1
13Alteration of growth responses in established cardiac pressure overload hypertrophy in rats with aortic banding显示文摘Schunkert H Weinberg EO Bruckschlegel G 1995J Clin Invest1995,96,6:1
14Implications of small reference vessel diameter in patients undergoing percutaneous coronary revascularization显示文摘 Harrell L Palacios IF 1999J Am Coll Cardiol1999,34,:1
15Effects of hormone replacement therapies on fibrinogen and plasma viscosity in postmennopausal women显示文摘Frohlich M Schunkert H Hensc HW 1997Coron Artery Dis1997,8,89:1
16Effect of estrogen replacement therapy on renin-angiotensin system in postmenopausal women显示文摘Schunkert H Danser AH Hense HW Derkx FH Kurzinger S Riegger GA 1997Circulation1997,95,1:1
17Role of apoptosis in myocardial stunning after open heart surgery显示文摘SCHMITr J P SCHRODER J SCHUNKERT H 2002Ann Thorac Surg2002,73,4:1
18Effects of hormone replacement therapies on fibrinogen and ptasma viscosity in postmennopausal women显示文摘Frohlich M Schunkert HW 1997Coron Artery Dis1997,8,89:1
19Alteration of growth responses in established cardiac pressure overload hypertrophy in rats with aortic banding显示文摘Schunkert H Weinberg EO Bruckschlegel G 1995J Clin Invest1995,96,6:1
20Evidence for a vasopressin system in the rat heart显示文摘Hupf H Grimm D Schunkert H 1999Circ Res1999,84,3:1
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