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| 1 | Severe acute pancreatitis: Pathogenetic aspects and prognostic factors显示文摘Approximately 20% of patients with acute pancreatitis develop a severe disease associated with complications and high risk of mortality. The purpose of this study is to review pathogenesis and prognostic factors of severe acute pancreatitis (SAP). An extensive medline search was undertaken with focusing on pathogenesis, complications and prognostic evaluation of SAP. Cytokines and other inflammatory markers play a major role in the pathogenesis and course of SAP and can be used as prognostic markers in its early phase. Other markers such as simple prognostic scores have been found to be as effective as multifactorial scoring systems (MFSS) at 48 h with the advantage of simplicity, efficacy, low cost, accuracy and early prediction of SAP. Recently, several laboratory markers including hematocrit, blood urea nitrogen (BUN), creatinine, matrix metalloproteinase-9 (MMP-9) and serum amyloid A (SAA) have been used as early predictors of severity within the first 24 h. The last few years have witnessed a tremendous progress in understanding the pathogenesis and predicting the outcome of SAP. In this review we classified the prognostic markers into predictors of severity, pancreatic necrosis (PN), infected PN (IPN) and mortality. | Ibrahim A Al Mofleh | 2008 | World Journal of Gastroenterology2008，14，5： | 67 |
| 2 | Hepatocellular carcinoma: Epidemiology, risk factors and pathogenesis显示文摘Hepatocellular carcinoma (HCC) is the commonest primary malignant cancer of the liver in the world. Given that the burden of chronic liver disease is expected to rise owing to increasing rates of alcoholism, hepatitis B and C prevalence and obesity-related fatty liver disease, it is expected that the incidence of HCC will also increase in the foreseeable future. This article summarizes the international epidemiology, the risk factors and the pathogenesis of HCC, including the roles of viral hepatitis, toxins, such as alcohol and aflatoxin, and insulin resistance. | Asmaa Ibrahim Gomaa Shahid A Khan Mireille B Toledano Imam Waked Simon D Taylor- Robinson | 2008 | World Journal of Gastroenterology2008，14，27： | 78 |
| 3 | Biliary complications following liver transplantation显示文摘Biliary tract complications are the most common complications after liver transplantation.These complications are encountered more commonly as a result of increased number of liver transplantations and the prolonged survival of transplant patients.Biliary complications remain a major source of morbidity in liver transplant patients,with an incidence of 5%-32%.Post liver transplantation biliary complications include strictures(anastomotic and non-anastomotic),leaks,stones,sphincter of Oddi dysfunction,and recurrence of primary biliary disease such as primary sclerosing cholangitis and primary biliary cirrhosis.The risk of occurrence of a specific biliary complication is related to the type of biliary reconstruction performed at the time of liver transplantation.In this article we seek to review the major biliary complications and their relation to the type of biliary reconstruction performed at the time of liver tranplantation. | Gursimran Kochhar Jose Mari Parungao Ibrahim A Hanouneh Mansour A Parsi | 2013 | World Journal of Gastroenterology2013，19，19： | 41 |
| 4 | Antimicrobial activity of Sapindus mukorossi and Rheum emodi extracts against H pylori: In vitro and in vivo studies显示文摘AIM: To evaluate the antibacterial activity of Sapindus mukorossi (S. mukorossi) and Rheum emodi (R. emodi). METHODS: Powders of S. mukorossi and R. emodi were extracted successively with petroleum ether, benzene, chloroform and ethanol and were concentrated in vacuum. The disk diffusion method was used for in vitro studies and in vivo studies were performed on male Wister rats. Thirty resistant clinical isolates of H pylori, as determined by their antibiotic sensitivity patterns by E-test, along with two Gram +ve (S. aureus, B. subtilis) and two Gram -ve (E. coli, P. vugaris) organisms were screened for their susceptibility patterns against these extracts. RESULTS: In our screening, all 30 resistant isolates and the other four organisms (two Gram +ve S. aureus, B. subtilis and two Gram -ve, E. coli, P. vugaris) were sensitive to the test compounds. It was found that ethanol and chloroform extracts of S. mukorossi and ethanol and benzene extracts of R. emodi inhibited H pylori at very low concentrations. In the in vitro study, the isolates showed a considerable zone of inhibition at very low concentrations (10 μg/mL) for both the extracts. In the in vivo study, the H pylori infection was cleared with minimal doses of extracts of S. mukorossi (2.5 mg/mL) and R. emodi (3.0 mg/mL) given orally for seven days. CONCLUSION: We can conclude from this study that the extracts of S. mukorossi and R. emodi inhibited the growth of pylori in vitro and, in in vivo studies, the H pylori infection cleared within seven days at very low concentrations. We also found that H pylori did not acquire resistance against these herbal extracts even after 10 consecutive passages. | Mohammed Ibrahim Aleem A Khan Santosh K Tiwari Mohammed Aejaz Habeeb MN Khaja CM Habibullah | 2006 | World Journal of Gastroenterology2006，12，44： | 46 |
| 5 | Comparison of early enteral nutrition in severe acute pancreatitis with prebiotic fiber supplementation versus standard enteral solution:A prospective randomized double-blind study显示文摘AIM: To compare the benefi cial effects of early enteral nutrition (EN) with prebiotic fiber supplementation in patients with severe acute pancreatitis (AP).METHODS: Thirty consecutive patients with severe AP, who required stoppage of oral feeding for 48 h, were randomly assigned to nasojejunal EN with or without prebiotics. APACHE Ⅱ score, Balthazar’s CT score and CRP were assessed daily during the study period.RESULTS: The median duration of hospital stay was shorter in the study group [10 ± 4 (8-14) d vs 15 ± 6 (7-26) d] (P < 0.05). The median value of days in intensive care unit was also similar in both groups [6 ± 2 (5-8) d vs 6 ± 2 (5-7) d]. The median duration of EN was 8 ± 4 (6-12) d vs 10 ± 4 (6-13) d in the study and control groups, respectively (P > 0.05). Deaths occurred in 6 patients (20%), 2 in the study group and 4 in the control group. The mean duration of APACHE Ⅱ normalization (APACHE Ⅱ score < 8) was shorter in the study group than in the control group (4 ± 2 d vs 6.5 ± 3 d, P < 0.05). The mean duration of CRP normalization was also shorter in the study group than in the control group (7 ± 2 d vs 10 ± 3 d, P < 0.05).CONCLUSION: Nasojejunal EN with prebiotic fiber supplementation in severe AP improves hospital stay, duration nutrition therapy, acute phase response and overall complications compared to standard EN therapy. | Tarkan Karakan Meltem Ergun Ibrahim Dogan Mehmet Cindoruk Selahattin Unal | 2007 | World Journal of Gastroenterology2007，13，19： | 50 |
| 6 | MicroRNA let-7b targets important cell cycle molecules in malignant melanoma cells and interferes with anchorage-independent growth显示文摘一幅 microRNA 表示屏幕被执行从良性的 melanocytic nevi 在 laser-microdissected 纸巾分析 157 不同 microRNAs (n = 10 ) 并且主要恶意的黑瘤(n = 10 ) ,用量的即时 PCR。微分表示被作出对有利的裁决 72 microRNAs。microRNAs 的 let-7 家庭的成员是显著地, down 作为与良性的 nevi 相比在主要黑瘤调整了,为是的这些分子的一个可能的角色暗示肿瘤在恶意的黑瘤压制 ors。有趣地,类似的调查结果为肺和结肠癌被描述了。在黑瘤房间试管内 down 的 let-7b 的 Overexpression 调整了 cyclins 的表示 D1, D3,和 A,和 cyclin 依赖的 kinase (Cdk ) 4,所有哪个被描述了在黑瘤开发起一个作用。蛋白质表示上的 let-7b 的效果由于单个 mRNAs 的 3'-untranslated 区域(3'UTRs ) 指向,为 cyclin D1 由记者基因分析例示。与它细胞周期管理者上的 down modulating 效果一致, let-7b 禁止了细胞周期前进和黑瘤细胞的抛锚无关的生长。总起来说,这些调查结果不仅指向早黑瘤开发的新规章的机制,而且可以打开大街因为未来指向了这个肿瘤的治疗。 | Julia Schultz Peter Lorenz Gerd Gross Saleh Ibrahim Manfred Kunz | 2008 | Cell Research2008，18，5： | 45 |
| 7 | Relationship Between Grain Yield and Yield Components in Super Hybrid Rice显示文摘Chinese super hybrid rice breeding project has developed many new varieties with great yield potential. It is controversial which yield component should be emphasized in super hybrid rice production. The present study was conducted to compare super hybrid rice with common hybrid and super inbred rice and analyze contributions of yield components to grain yield of super hybrid rice under experimental conditions, and evaluate relationships between grain yield and yield components of super hybrid rice in farmer’s paddy fields. Field experiments were done in Changsha, Guidong, and Nanxian, Hunan Province, China, from 2007 to 2009. Eight super hybrid varieties, one common hybrid variety, and one super inbred variety were grown in each location and year. Rice production investigation was undertaken in high-yielding (Guidong), moderate-yielding (Nanxian), and low-yielding (Ningxiang) regions of Hunan Province, China, in 2009. Grain yield and yield components were measured in both the field experiments and rice production investigation. Super hybrid rice varieties outyielded common hybrid and super inbred varieties across three locations and years. Yield potential has been increased by 11.4% in super hybrid rice varieties compared with common and super inbred varieties. The higher yield of super hybrid varieties was attributed to improvement in panicle size. Panicles per m2 had the highest positive contribution to grain yield with the exception under yield level of 10.0 to 12.0 t ha-1, and was positively related to grain yield in farmer’s field at all of the high-, moderate-, and low-yielding regions. Our study suggests that panicle per m2 ought to be emphasized in super hybrid rice production. | HUANG Min ZOU Ying-bin JIANG Peng XIA Bing Md Ibrahim AO He-jun | 2011 | Agricultural Sciences in China2011，10，10： | 41 |
| 8 | Gastrointestinal bezoars: A retrospective analysis of 34 cases显示文摘AIM: Bezoars (BZ) are the most common foreign bodies of gastrointestinal tract. Clinical manifestations vary depending on the location of BZ from no symptoms to acute abdominal syndrome. When located in small bowel, they frequently cause small bowel obstruction (SBO). We aimed to present our experience by reviewing literature.METHODS: Thirty-four patients with gastrointestinal BZ were presented. The data were collected from hospital records and analyzed retrospectively. Morbidity and mortality rates were statistically analyzed between the subgroups according to SBO and endoscopic or surgical treatment modalities.RESULTS: The 34 patients had phytobezoars (PBZ). Two patients with mental retardation and trichotillomania had trichobezoars (TBZ). More than half of them (55.88%) had previous gastric surgery. Also most of them had small bowel bezoars resulting in obstruction. Surgical and endoscopic morbidity rates were 32.14% and 14.28% respectively.The total morbidity rate of this study was 29.41%. Four patients in surgically treated group died. There was no death in endoscopically treated group. The total and surgical mortality rates were 11.76% and 14.28% respectively. The differences in morbidity and mortality rates between the subgroups were not statistically significant.CONCLUSION: BZ are commonly seen in stomach and small intestine. SBO is the most common complication.When uncomplicated, endoscopic or surgical removal can be applied easily. | Kenan Erzurumlu Zafer Malazgirt Ahmet Bektas Adem Dervisoglu Cafer Polat Gokhan Senyurek Ibrahim Yetim Kayhan Ozkan | 2005 | World Journal of Gastroenterology2005，11，12： | 33 |
| 9 | “三定”栽培对双季超级稻养分吸收积累及氮肥利用率的影响显示文摘为探讨南方双季超级稻对氮、磷、钾养分的吸收积累及利用规律,于2008—2010年在湖南长沙和浏阳以超级早稻陆两优996、陵两优268和超级晚稻丰源优299、天优华占为材料进行大田定位试验,比较了'三定'栽培、免耕摆栽和传统栽培条件下双季超级稻不同生育期植株体内氮、磷、钾吸收积累特点及氮肥利用率。与传统栽培相比,'三定'栽培双季超级稻生长前期(分蘖中期)氮、磷、钾的吸收量较低,幼穗分化期差异小,而齐穗期(早季平均为10.71、2.23和11.82gm?2,晚季平均为12.25、2.69和16.37gm?2)和成熟期(早季平均为13.61、3.01和13.71gm?2,晚季平均为17.16、3.31和18.31gm?2)较高;氮肥的偏生产力(平均为53.40kgkg?1)、吸收利用率(平均为55.98%)、农学利用率(平均为22.27kgkg?1)较高,分别提高29.00%、88.92%和46.67%。免耕摆栽双季超级稻不同生育时期氮、磷、钾的吸收特点与'三定'栽培相似,但其氮肥的偏生产力、吸收利用率和农学利用率(平均为50.24kgkg?1、52.75%和19.33kgkg?1)分别比'三定'栽培降低6.29%、6.12%和15.19%。由此可见,双季超级稻生产采用'三定'栽培技术有利于提高氮肥利用率。 | 蒋鹏 黄敏 Md. Ibrahim 曾燕 夏冰 施婉菊 谢小兵 邹应斌 | 2011 | 作物学报2011，37，12： | 33 |
| 10 | 多级分离缓冲马铃薯收获机设计与试验显示文摘针对云南山地黏土条件下马铃薯机械化收获分离效果差、明薯率低、伤薯率和破皮率较高等问题,采用多级分离振动、多重缓冲和低位侧铺的方式,设计了一种多级分离缓冲马铃薯收获机。在阐述机具整体结构及工作原理的基础上,通过理论计算确定了挖掘装置、多级分离缓冲装置、主动振动装置等主要关键部件的结构参数;建立抛送分离阶段薯土运动模型,获取微波浪形薯土分离相关技术特征;建立马铃薯筛面滑动模型,对薯块的运动特性进行理论分析,得出薯块顺流、回流的运动规律;分析土块在输送分离过程中的碰撞特性,确定了影响分离破碎效果的因素。以含杂率和土壤覆盖度为试验指标,采用二次旋转正交组合试验设计方法进行了空载试验,并利用高速摄影和三轴姿态传感器实时获取分离筛上土壤的分布状态和运动规律,结果表明,分离筛最佳工作参数组合为:一级分离筛线速度1.42 m/s、二级分离筛线速度2.2 m/s、侧输出线速度1 m/s,此时土壤覆盖度69.11%,含杂率2.56%。在分离筛最佳工作参数组合下,以明薯率、破皮率和伤薯率为试验指标进行了田间收获试验,结果表明:当工作速度1.05 m/s、挖掘深度180 mm、振动强度Ⅱ级、筛面倾角22°时,明薯率为99.1%、破皮率为1.41%、伤薯率为1.32%,各项性能指标均符合国家行业标准要求。 | 张兆国 王海翼 李彦彬 杨曦 IBRAHIM Issa 张振东 | 2021 | 农业机械学报2021，52，2： | 27 |
| 11 | Laparoscopic liver resections for hepatocellular carcinoma:Current role and limitations显示文摘Liver resection for hepatocellular carcinoma(HCC)is currently known to be a safer procedure than it was before because of technical advances and improvement in postoperative patient management and remains the first-line treatment for HCC in compensated cirrhosis.The aim of this review is to assess current indications,advantages and limits of laparoscopic surgery for HCC resections.We also discussed the possible evolution of this surgical approach in parallel with new technologies. | Martin Gaillard Hadrien Tranchart Ibrahim Dagher | 2014 | World Journal of Gastroenterology2014，20，17： | 25 |
| 12 | Hepatoprotective activity of Sapindus mukorossi and Rheum emodi extracts: In vitro and in vivo studies显示文摘AIM: To study the hepatoprotective capacity of Sapindus mukorossi (S. mukorossi) and Rheum emodi (R. emodi) extracts in CCl4 treated male rats. METHODS: The dried powder of S. mukorossi and R. emodi was extracted successively with petroleum ether, benzene, chloroform, and ethanol and concentrated in vacuum. Primary rat hepatocyte monolayer cultures were used for in vitro studies. In vivo, the hepatoprotective capacity of the extract of the fruit pericarp of S. mukorossi and the rhizomes of R. emodi was analyzed in liver injured CCl4-treated male rats. RESULTS: In vitro: primary hepatocytes monolayer cultures were treated with CCl4 and extracts of S. mukorossi & R. emodi. A protective activity could be demonstrated in the CCl4 damaged primary monolayer culture. In vivo : extracts of the fruit pericarp of S. mukorossi (2.5 mg/mL) and rhizomes of R. emodi (3.0 mg/mL) were found to have protective properties in rats with CCl4 induced liver damage as judged from serum marker enzyme activities. CONCLUSION: The extracts of S. mukorossi and R. emodi do have a protective capacity both in vitro on primary hepatocytes cultures and in in vivo in a rat model of CCl4 mediated liver injury. | Mohammed Ibrahim Mohammed Nane Khaja Anjum Aara Aleem Ahmed Khan Mohammed Aejaz Habeeb Yalavarthy Prameela Devi Mangamoori Lakshmi Narasu Chitoor Mohammed Habibullah | 2008 | World Journal of Gastroenterology2008，14，16： | 24 |
| 13 | Respiratory Distress Resulting from Gastroesophageal Reflux Is not Asthma,but Laryngotracheal Irritation,Spasm,even Suffocation显示文摘DESPITE the strong association between gastroesophageal reflux disease (GERD) and asthma has been undisputedly established and widely recognized by experts in advanced countries. Yet few topics in medicine are as controversial | Zhong-gao Wang Ji-min Wu Jian-jun Liu Li-yin Wang Yun-gang Lai Ibrahim M Ibrahim Xiu-jie Wang Herbert Dardik | 2009 | Chinese Medical Sciences Journal2009，24，2： | 20 |
| 14 | Blunt trauma related chest wall and pulmonary injuries: An overview显示文摘Physical traumas are tragic and multifaceted injuries that suddenly threaten life.Although it is the third most common cause of death in all age groups,one out of four trauma patients die due to thoracic injury or its complications.Blunt injuries constitute the majority of chest trauma.This indicates the im porta nee of chest trauma among all traumas.Blunt chest trauma is usually caused by motor vehicle accident,falling from height,blunt instrument injury and physical assault.As a result of chest trauma,many injuries may occur,such as pulm onary injuries,and these require urge nt in terve ntion.Chest wall and pulmonary injuries range from rib fractures to flail chest,pneumothorax to hemothorax and pulmonary contusion to tracheobronchial injuries.Following these injuries,patients may present with a simple dyspnea or even respiratory arrest.For such patie nt,it is imports nt to understa nd the treatme nt logic and to take a multidisciplinary approach to treat the pulmonary and chest wall injuries.This is because only 10%of thoracic trauma patients require surgical operation and the remaining 90%can be treated with simple methods such as appropriate airway,oxygen support,maneuvers,volume support and tube thoracostomy.Adequate pain control in chest trauma is sometimes the most basic and best treatment.With definite diagnosis,the morbidity and mortality can be significantly reduced by simple treatment methods. | Bekir Nihat Dogrul Ibrahim Kiliccalan Ekrem Samet Asci Selim Can Peker | 2020 | Chinese Journal of Traumatology2020，23，3： | 19 |
| 15 | Research and development in agricultural robotics:A perspective of digital farming显示文摘Digital farming is the practice of modern technologies such as sensors,robotics,and data analysis for shifting from tedious operations to continuously automated processes.This paper reviews some of the latest achievements in agricultural robotics,specifically those that are used for autonomous weed control,field scouting,and harvesting.Object identification,task planning algorithms,digitalization and optimization of sensors are highlighted as some of the facing challenges in the context of digital farming.The concepts of multi-robots,human-robot collaboration,and environment reconstruction from aerial images and ground-based sensors for the creation of virtual farms were highlighted as some of the gateways of digital farming.It was shown that one of the trends and research focuses in agricultural field robotics is towards building a swarm of small scale robots and drones that collaborate together to optimize farming inputs and reveal denied or concealed information.For the case of robotic harvesting,an autonomous framework with several simple axis manipulators can be faster and more efficient than the currently adapted professional expensive manipulators.While robots are becoming the inseparable parts of the modern farms,our conclusion is that it is not realistic to expect an entirely automated farming system in the future. | Redmond Ramin Shamshiri Cornelia Weltzien Ibrahim A.Hameed Ian J.Yule Tony E.Grift Siva K.Balasundram Lenka Pitonakova Desa Ahmad Girish Chowdhary | 2018 | International Journal of Agricultural and Biological Engineering2018，11，4： | 17 |
| 16 | From pollutant to solution of wastewater pollution: Synthesis of activated carbon from textile sludge for dye adsorption显示文摘Adsorption is an important process in wastewater treatment,and conversion of waste materials to adsorbent offers a solution to high material cost related to the use of commercial activated carbon.This study investigated the adsorption behaviour of Reactive Black 5(RB5)and methylene blue(MB)onto activated carbon produced from textile sludge(TSAC).The activated carbon was synthesized through chemical activation of precursor followed with carbonization at 650°C under nitrogen flow.Effects of time(0–200 min),pH(2–10),temperature(25–60°C),initial dye concentration(0–200 mg·L^(-1)),and adsorbent dosage(0.01–0.15 g)on dye removal efficiency were investigated.Preliminary screening revealed that TSAC synthesized via H_2SO_4activation showed higher adsorption behaviour than TSAC activated by KCl and ZnCl_2.The adsorption capacity of TSAC was found to be 11.98 mg·g^(-1)(RB5)and 13.27 mg·g^(-1)(MB),and is dependent on adsorption time and initial dye concentration.The adsorption data for both dyes were well fitted to Freundlich isotherm model which explains the heterogeneous nature of TSAC surface.The dye adsorption obeyed pseudo-second order kinetic model,thus chemisorption was the controlling step.This study reveals potential of textile sludge in removal of dyes from aqueous solution,and further studies are required to establish the applicability of the synthesized adsorbent for the treatment of waste water containing toxic dyes from textile industry. | Syieluing Wong Nurul Atiqah Najlaa Yac'cob Norzita Ngadi Onn Hassan Ibrahim M.Inuwa | 2018 | Chinese Journal of Chemical Engineering2018，26，4： | 16 |
| 17 | A survey on trust based detection and isolation of malicious nodes in ad-hoc and sensor networks显示文摘 | Adnan AHMED Kamalrulnizam ABU BAKAR Muhammad Ibrahim CHANNA Khalid HASEEB Abdul Waheed KHAN | 2015 | Frontiers of Computer Science2015，9，2： | 15 |
| 18 | Prevalence of osteoporosis and vertebral fractures and related factors in patients with ankylosing spondylitis显示文摘 | Mehmet Ali Ulu ibrahim Batmaz Banu Dilek Remzi Cevik | 2014 | Chinese Medical Journal2014，，15： | 15 |
| 19 | Radioembolization for the treatment of unresectable hepatocellular carcinoma:A clinical review显示文摘Hepatocellular carcinoma(HCC)is the sixth most common cancer in the world.The majority of patients with HCC present with unresectable disease.These patients have historically had limited treatment options secondary to HCC demonstrating chemoresistance to the currently available systemic therapies.Additionally, normal liver parenchyma has shown intolerance to tumoricidal radiation doses,limiting the use of external beam radiation.Because of these limitations,novel percutaneous liver-directed therapies have emerged. The targeted infusion of radioactive microspheres (radioembolization)represents one such therapy. Radioembolization is a minimally invasive transcatheter therapy through which radioactive microspheres are infused into the hepatic arteries that supply tumor. Once infused,these microspheres traverse the hepatic vascular plexus and selectively implant within the tumor arterioles.Embedded within the arterioles, the 90Y impregnated microspheres emit high energy and low penetrating radiation doses selectively to the tumor.Radioembolization has recently shown promise for the treatment of patients with unresectable HCC. The objective of this review article is to highlight twocurrently available radioembolic devices(90Y,188Rh)and provide the reader with a recent review of the literature. | Saad M Ibrahim Robert J Lewandowski Kent T Sato Vanessa L Gates Laura Kulik Mary F Mulcahy Robert K Ryu Reed A Omary Riad Salem | 2008 | World Journal of Gastroenterology2008，14，11： | 14 |
| 20 | 应用聚合酶链式反应检测禽痘病毒田间分离株及疫苗株中网状内皮组织增殖病毒LTR片断,env及re1基因显示文摘本文利用聚合酶链式反应对来自澳大利亚昆士兰州、维多利亚州和新南维尔士州的4株禽痘病毒田间分离株及二疫苗株中网状内皮组织增殖病毒的LTR片断、env及rel基因因进行了检测。所有4株痘病毒分离株均为LTR片断、env阳性,曾被PCR证实为LTR阳性的一疫苗株在本实验中也为LTR、env阳性,另一疫苗株为LTR、env阴性,所有上述禽痘病毒株均为rel阴性。 | 段宏安 IBRAHIM DIALLO PETER SPRADBROW WAYNE ROBINSON | 1999 | 中国兽医杂志1999，25，8： | 14 |
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