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| 1 | Life prognosis of sentinel node navigation surgery for early-stage gastric cancer:Outcome of lymphatic basin dissection显示文摘BACKGROUND Lymphatic basin dissection is a sentinel node biopsy method that is specific for gastric cancer.In this method,the dyed lymphatic system is dissected en bloc,and sentinel nodes are identified at the back table(ex vivo).Even with lymphatic basin dissection,blood flow to the residual stomach can be preserved,and functionpreserving curative gastrectomy can be performed.The oncological safety of function-preserving curative gastrectomy combined with lymphatic basin dissection has not yet been fully investigated.We hypothesized that the oncological safety of sentinel node navigation surgery(SNNS)is not inferior to that of the guidelines.AIM To investigate the life prognosis of SNNS for gastric cancer in comparison with guidelines surgery.METHODS This was a retrospective cohort study.Patients were selected from gastric cancer patients who underwent sentinel node biopsy from April 1999 to March 2016.Patients from April 1999 to August 2008 were from the Department of Surgery II,Kanazawa University Hospital,and patients from August 2009 to March 2016 were from the Department of Surgical Oncology,Kanazawa Medical University Hospital.Patients who were diagnosed with gastric cancer,which was preoperatively diagnosed as superficial type(type 0),5 cm or less in length,clinical T1-2 and node negative,and underwent various gastrectomies guided by sentinel node navigation were retrospectively collected.The overall survival(OS)and relapsefree survival(RFS)of these patients(SNNS group)were investigated.Patients with gastric cancer of the same stage and who underwent guidelines gastrectomy with standard nodal dissection were also selected as the control group.RESULTS A total of 239 patients in the SNNS group and 423 patients in the control group were included.Pathological nodal metastasis was observed in 10.5%and 10.4%of the SNNS and control groups,respectively.The diagnostic abilities of sentinel node biopsy were 84%and 98.6%for sensitivity and accuracy,respectively.In the SNNS group,81.6%of patients underwent modified gastrectomy or functionpreserving curative gastrectomy with lymphatic basin dissection,in which the extent of nodal dissection was further reduced compared to the guidelines.The OS rate in the SNNS group was 96.8%at 5 years and was significantly better than 91.3%in the control group(P=0.0014).The RFS rates were equal in both groups.After propensity score matching,there were 231 patients in both groups,and the cumulative recurrence rate was 0.43%at 5 years in the SNNS group and 1.30%in the control group,which was not statistically different.CONCLUSION The oncological safety of patients who undergo gastrectomy guided by sentinel node navigation is not inferior to that of the guidelines surgery. | Shinichi Kinami Naohiko Nakamura Tomoharu Miyashita Hidekazu Kitakata Sachio Fushida Takashi Fujimura Yasuo Iida Noriyuki Inaki Toru Ito Hiroyuki Takamura | 2021 | World Journal of Gastroenterology2021，27，46： | 5 |
| 2 | 在有阴暗胃肠的流血的病人的囊内视镜检查法的计算图象修正的功效显示文摘 AIM:To investigate whether flexible spectral color enhancement(FICE) improves diagnostic yields of capsule endoscopy(CE) for obscure gastro-intestinal bleeding(OGIB).METHODS:The study subjects consisted of 81 patients.Using FICE,there were three different sets with different wavelengths.Using randomly selected sets of FICE,images of CE were evaluated again by two individuals who were not shown the conventional CE reports and findings.The difference between FICE and conventional imaging was examined.RESULTS:The overall diagnostic yields in FICE sets 1,2,3 and conventional imaging(48.1%) were 51.9%,40.7%,51.9% and 48.1%,respectively,which showed no statistical difference compared to conventional imaging.The total numbers of detected lesions per examination in FICE imaging and conventional imaging were 2.5 ± 2.1 and 1.8 ± 1.7,respectively,which showed a significant difference(P = 0.01).CONCLUSION:The diagnostic yield for OGIB is not improved by FICE.However,FICE can detect significantly more small bowel lesions compared to conventional imaging. | Tomoaki Matsumura Makoto Arai Toru Sato Tomoo Nakagawa Daisuke Maruoka Masaru Tsuboi Sachio Hata Eiji Arai Tatsuro Katsuno Fumio Imazeki Osamu Yokosuka | 2012 | World Journal of Gastrointestinal Endoscopy2012，4，9： | 4 |
| 3 | Geochemical and stable isotopic studies of Gulf of Suez’s hot springs,Egypt显示文摘The Gulf of Suez region is one of the most interesting geothermal areas in Egypt because of the high temperatures of its springs.The eastern and western shores of the Gulf of Suez are characterized by superficial thermal manifestations including a cluster of hot springs with varied temperatures.Variations of deuterium and oxygen-18 concentrations in thermal waters have been used to aid in describing the source of recharge in the Gulf of Suez hot springs.Isotope and geochemical data for the Gulf of Suez thermal waters suggest that recharge to the hot springs may not be entirely from the Gulf of Suez water,but possibly from the meteoric water that comes from areas of higher altitude surrounding the hot springs. | Mohamed Abdel Zaher Hakim Saibi Sachio Ehara | 2012 | Chinese Journal Of Geochemistry2012，31，2： | 3 |
| 4 | Intraoperative lavage for cytological examination in 1,297 patients with gastric carcinoma显示文摘 | Etsuro Bando Yutaka Yonemura Keizo Taniguchi Toshiaki Yasui Sachio Fushida Takashi Fujimura Gen-ichi Nishimura Koichi Miwa | 1999 | The American Journal of Surgery1999，，3： | 2 |
| 5 | Plasma Brain Natriuretic Peptide Levels Increase in Proportion to the Extent of Right Ventricular Dysfunction in Pulmonary Hypertension显示文摘 | Noritoshi Nagaya Toshio Nishikimi Yoshiaki Okano Masaaki Uematsu Toru Satoh Shingo Kyotani Sachio Kuribayashi Seiki Hamada Mikio Kakishita Norifumi Nakanishi Makoto Takamiya Takeyoshi Kunieda Hisayuki Matsuo Kenji Kangawa | 1998 | Journal of the American College of Cardiology1998，，1： | 2 |
| 6 | Role of MMP-7 in the formation of peritoneal dissemination in gastric cancer显示文摘 | Yutaka Yonemura Yoshio Endou Hideto Fujita Sachio Fushida Etsurou Bandou Keizou Taniguchi Kouichi Miwa Kazuo Sugiyama Takuma Sasaki | 2000 | Gastric Cancer2000，，2： | 2 |
| 7 | PTD classification: proposal for a new classification of gastric cancer location based on physiological lymphatic flow显示文摘 | Shinichi Kinami Takashi Fujimura Eisuke Ojima Sachio Fushida Toshihiko Ojima Hiroshi Funaki Hideto Fujita Hiroyuki Takamura Itasu Ninomiya Genichi Nishimura Masato Kayahara Tetsuo Ohta Zen Yoh | 2008 | International Journal of Clinical Oncology2008，，4： | 2 |
| 8 | Emphysematous cholecystitis with massive gas in the abdominal cavity显示文摘Emphysematous cholecystitis is a rare variant of acute cholecystitis with a high mortality rate.The combination of emphysematous cholecystitis and pneumoperitoneum is also rare.We herein describe a case of emphysematous cholecystitis with massive gas in the abdominal cavity.A 77-year-old male presented with epigastric pain and lassitude lasting for one week.A computed tomography scan demonstrated massive gas in the abdominal cavity.Gas was also detectable inside the gallbladder.Massive ascites as well as a pleural effusion were also detected.Under the diagnosis of perforation of the digestive tract,we performed emergency surgery.Beyond our expectations,the perforation site was not in the alimentary tract,but rather in the gallbladder.We then diagnosed the patient with emphysematous cholecystitis with perforation,and performed cholecystectomy.A pathological examination of the resected gallbladder revealed necrosis in the mucosa and thinning of the wall.Cultures of the ascites detected Clostridium perfringens,a gas-producing microorganism. | Hiroyuki Miyahara Dai Shida Hiroki Matsunaga Yukiko Takahama Sachio Miyamoto | 2013 | World Journal of Gastroenterology2013，19，4： | 2 |
| 9 | Inherited cardiomyopathies caused by troponin mutations显示文摘Genetic investigations of cardiomyopathy in the recent two decades have revealed a large number of mutations in the genes encoding sarcomeric proteins as a cause of inherited hypertrophic cardiomyopathy (HCM), dilated cardiomyopathy (DCM), or restrictive cardiomyopathy (RCM). Most functional analyses of the effects of mutations on cardiac muscle contraction have revealed significant changes in the Ca2+-regulatory mechanism, in which cardiac troponin (cTn) plays important structural and functional roles as a key regulatory protein. Over a hundred mutations have been identified in all three subunits of cTn, i.e., cardiac troponins T, I, and C. Recent studies on cTn mutations have provided plenty of evidence that HCM- and RCM-linked mutations increase cardiac myofilament Ca2+ sensitivity, while DCM-linked mutations decrease it. This review focuses on the functional consequences of mutations found in cTn in terms of cardiac myofilament Ca2+ sensitivity, ATPase activity, force generation, and cardiac troponin I phosphorylation, to understand potential molecular and cellular pathogenic mechanisms of the three types of inherited cardiomyopathy. | Qun-Wei Lu Xiao-Yan Wu Sachio Morimoto | 2013 | Journal of Geriatric Cardiology2013，10，1： | 2 |
| 10 | Hyperthermo-chemotherapy combined with cytoreductive surgery for the treatment of gastric cancer with peritoneal dissemination显示文摘 | Yutaka Yonemura M.D. Takashi Fujimura M.D. Sachio Fushida M.D. Shigeru Takegawa M.D. Toru Kamata M.D. Kanji Katayama M.D. Takeo Kosaka M.D. Akio Yamaguchi M.D. Kouichi Miwa M.D. Ituo Miyazaki M.D | 1991 | World Journal of Surgery1991，，4： | 1 |
| 11 | Intraoperative lavage for cytological examination in 1,297 patients with gastric carcinoma显示文摘 | Etsuro Bando Yutaka Yonemura Keizo Taniguchi Toshiaki Yasui Sachio Fushida Takashi Fujimura Gen-ichi Nishimura Koichi Miwa | 1999 | The American Journal of Surgery1999，，3： | 1 |
| 12 | The role of human peritoneal mesothelial cells in the fibrosis and progressionof gastric cancer显示文摘 | Tomoya Tsukada Sachio Fushida Shinichi Harada Yasumichi Yagi Jun Kinoshita Katsunobu Oyama Hidehiro Tajima Hideto Fujita Itasu Ninomiya Takashi Fujimura Tetsuo Ohta | 2012 | International Journal of Oncology2012，，2： | 1 |
| 13 | The management of a remnant pancreatic stump for preventing the development of postoperative pancreatic fistulas after distal pancreatectomy: current evidence and our strategy显示文摘 | Isamu Makino Hirohisa Kitagawa Hisatoshi Nakagawara Hidehiro Tajima Itasu Ninomiya Sachio Fushida Takashi Fujimura Tetsuo Ohta | 2013 | Surgery Today2013，，6： | 1 |
| 14 | Intraperitoneal hyperthermic treatment for peritoneal dissemination of colorectal cancers显示文摘 | Dr. Akio Yamaguchi M. D. Yuuji Tsukioka M. D. Sachio Fushida M. D. Yoshiyuki Kurosaka M. D. Masahiro Kanno M. D. Yutaka Yonemura M. D. Kouichi Miwa M.D. Itsuo Miyazaki M. D | 1992 | Diseases of the Colon & Rectum1992，，10： | 1 |
| 15 | Hyperthermo-chemotherapy combined with cytoreductive surgery for the treatment of gastric cancer with peritoneal dissemination显示文摘 | Yutaka Yonemura M.D. Takashi Fujimura M.D. Sachio Fushida M.D. Shigeru Takegawa M.D. Toru Kamata M.D. Kanji Katayama M.D. Takeo Kosaka M.D. Akio Yamaguchi M.D. Kouichi Miwa M.D. Ituo Miyazaki M.D | 1991 | World Journal of Surgery1991，，4： | 1 |
| 16 | Antigenic differences in the H proteins of canine distemper viruses显示文摘 | Kiyoko Iwatsuki Sachio Tokiyoshi Norio Hirayama Kazuya Nakamura Kenjiro Ohashi Chiaki Wakasa Takeshi Mikami Chieko Kai | 2000 | Veterinary Microbiology2000，，3： | 1 |
| 17 | Microbial hydrogen production from sweet potato starch residue显示文摘 | Haruhiko Yokoi Akio Saitsu Hiroyuki Uchida Jun Hirose Sachio Hayashi Yoshiyuki Takasaki | 2001 | Journal of Bioscience and Bioengineering2001，，1： | 1 |
| 18 | Temperature and chemical changes in the fluids of the Obama geothermal field (SW Japan) in response to field utilization显示文摘 | Hakim S Sachio E | 2010 | Geothermics2010，39，： | 1 |
| 19 | Molecular dynamics simulations of solvated crystal models of cellulose Ⅰα and ⅢⅠ 显示文摘 | Toshifumi Yui Sachio Hayashi | 2007 | Biomacromolecules2007，8，： | 1 |
| 20 | Nuclear Factor-kappa Bactivation in the nasal polyp epithelium relationship to local cytokine gene expression显示文摘 | Taken Sachio Hirakawa Katsuhiro Veda Tsutomu | 2002 | Laryngoscope2002，112，1： | 1 |
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