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| 1 | Life prognosis of sentinel node navigation surgery for early-stage gastric cancer:Outcome of lymphatic basin dissection显示文摘BACKGROUND Lymphatic basin dissection is a sentinel node biopsy method that is specific for gastric cancer.In this method,the dyed lymphatic system is dissected en bloc,and sentinel nodes are identified at the back table(ex vivo).Even with lymphatic basin dissection,blood flow to the residual stomach can be preserved,and functionpreserving curative gastrectomy can be performed.The oncological safety of function-preserving curative gastrectomy combined with lymphatic basin dissection has not yet been fully investigated.We hypothesized that the oncological safety of sentinel node navigation surgery(SNNS)is not inferior to that of the guidelines.AIM To investigate the life prognosis of SNNS for gastric cancer in comparison with guidelines surgery.METHODS This was a retrospective cohort study.Patients were selected from gastric cancer patients who underwent sentinel node biopsy from April 1999 to March 2016.Patients from April 1999 to August 2008 were from the Department of Surgery II,Kanazawa University Hospital,and patients from August 2009 to March 2016 were from the Department of Surgical Oncology,Kanazawa Medical University Hospital.Patients who were diagnosed with gastric cancer,which was preoperatively diagnosed as superficial type(type 0),5 cm or less in length,clinical T1-2 and node negative,and underwent various gastrectomies guided by sentinel node navigation were retrospectively collected.The overall survival(OS)and relapsefree survival(RFS)of these patients(SNNS group)were investigated.Patients with gastric cancer of the same stage and who underwent guidelines gastrectomy with standard nodal dissection were also selected as the control group.RESULTS A total of 239 patients in the SNNS group and 423 patients in the control group were included.Pathological nodal metastasis was observed in 10.5%and 10.4%of the SNNS and control groups,respectively.The diagnostic abilities of sentinel node biopsy were 84%and 98.6%for sensitivity and accuracy,respectively.In the SNNS group,81.6%of patients underwent modified gastrectomy or functionpreserving curative gastrectomy with lymphatic basin dissection,in which the extent of nodal dissection was further reduced compared to the guidelines.The OS rate in the SNNS group was 96.8%at 5 years and was significantly better than 91.3%in the control group(P=0.0014).The RFS rates were equal in both groups.After propensity score matching,there were 231 patients in both groups,and the cumulative recurrence rate was 0.43%at 5 years in the SNNS group and 1.30%in the control group,which was not statistically different.CONCLUSION The oncological safety of patients who undergo gastrectomy guided by sentinel node navigation is not inferior to that of the guidelines surgery. | Shinichi Kinami Naohiko Nakamura Tomoharu Miyashita Hidekazu Kitakata Sachio Fushida Takashi Fujimura Yasuo Iida Noriyuki Inaki Toru Ito Hiroyuki Takamura | 2021 | World Journal of Gastroenterology2021，27，46： | 5 |
| 2 | Intraoperative lavage for cytological examination in 1,297 patients with gastric carcinoma显示文摘 | Etsuro Bando Yutaka Yonemura Keizo Taniguchi Toshiaki Yasui Sachio Fushida Takashi Fujimura Gen-ichi Nishimura Koichi Miwa | 1999 | The American Journal of Surgery1999，，3： | 2 |
| 3 | Role of MMP-7 in the formation of peritoneal dissemination in gastric cancer显示文摘 | Yutaka Yonemura Yoshio Endou Hideto Fujita Sachio Fushida Etsurou Bandou Keizou Taniguchi Kouichi Miwa Kazuo Sugiyama Takuma Sasaki | 2000 | Gastric Cancer2000，，2： | 2 |
| 4 | PTD classification: proposal for a new classification of gastric cancer location based on physiological lymphatic flow显示文摘 | Shinichi Kinami Takashi Fujimura Eisuke Ojima Sachio Fushida Toshihiko Ojima Hiroshi Funaki Hideto Fujita Hiroyuki Takamura Itasu Ninomiya Genichi Nishimura Masato Kayahara Tetsuo Ohta Zen Yoh | 2008 | International Journal of Clinical Oncology2008，，4： | 2 |
| 5 | Phase I/II study of intraperitoneal docetaxel plus S-1 for the gastric cancer patients with peritoneal carcinomatosis显示文摘 | S. Fushida J. Kinoshita M. Kaji Y. Hirono F. Goda Y. Yagi K. Oyama Y. Sudo Y. Watanabe T. Fujimura | 2013 | Cancer Chemotherapy and Pharmacology2013，，5： | 2 |
| 6 | Lymphangiogenesis and the vascular endothelial growth factor receptor (VEGFR)-3 in gastric cancer显示文摘 | Fushida S Bando E | 2001 | Eur J Cancer2001，37，7： | 1 |
| 7 | Lymphangiogenesis and the vascular endothelial growth factor receptor in gastric cancer显示文摘 | Yonemura Y Fushida S Bando E | 2001 | Eur J Cancer2001，37，7： | 1 |
| 8 | Pharmacologic study of intraperitoneal docetaxel in gastric cancer with peritoneal dissemination 显示文摘 | Fushida S Nao F Kinami S | 2002 | Gan Kagaku Ryoho2002，29，10： | 1 |
| 9 | Lymphangiogenensis and the vscular endothelial growth factor receptor(VEGFR) - 3 in gastric cancer显示文摘 | Yonemura Y Fushida S Bando E | 2001 | European journa of cancer2001，37，7： | 1 |
| 10 | Hyperthermo-chemotherapy combined with cytoreductive surgery for the treatment of gastric cancer with peritoneal dissemination显示文摘 | Yutaka Yonemura M.D. Takashi Fujimura M.D. Sachio Fushida M.D. Shigeru Takegawa M.D. Toru Kamata M.D. Kanji Katayama M.D. Takeo Kosaka M.D. Akio Yamaguchi M.D. Kouichi Miwa M.D. Ituo Miyazaki M.D | 1991 | World Journal of Surgery1991，，4： | 1 |
| 11 | Low-dose paclitaxel modulates tumour fibrosis in gastric cancer显示文摘 | Tsukada T Fushida S Harada S | | 0，，04： | 1 |
| 12 | Sentinel node navigation surgery in early stage gastric carcinoma:a limited gastric resection with lymphatic basin dissection in sentinel node negative patients显示文摘 | Miwa K Fujimura T Fushida S | 2003 | Nippon Geka Gakkai Zasshi2003，104，11： | 1 |
| 13 | Intraoperative lavage for cytological examination in 1,297 patients with gastric carcinoma显示文摘 | Etsuro Bando Yutaka Yonemura Keizo Taniguchi Toshiaki Yasui Sachio Fushida Takashi Fujimura Gen-ichi Nishimura Koichi Miwa | 1999 | The American Journal of Surgery1999，，3： | 1 |
| 14 | The role of human peritoneal mesothelial cells in the fibrosis and progressionof gastric cancer显示文摘 | Tomoya Tsukada Sachio Fushida Shinichi Harada Yasumichi Yagi Jun Kinoshita Katsunobu Oyama Hidehiro Tajima Hideto Fujita Itasu Ninomiya Takashi Fujimura Tetsuo Ohta | 2012 | International Journal of Oncology2012，，2： | 1 |
| 15 | Lymphangiogenesis and the vascular endothelial growth factor receptor (VEGFR) -3显示文摘 | Yonemura Y Fushida S Bando E | 2001 | EurJCancer2001，37，7： | 1 |
| 16 | Phaimacologic study of intraperito-neal docetaxel in gastric cancer with peritoneal dissemination显示文摘 | Fushida S Nao F KinamiS | 2002 | Can Kagaku Ryoho2002，29，10： | 1 |
| 17 | Increased expression of S100A4 and its prognostic significance in esophageal squamous cell carcinoma 显示文摘 | Ninomiya I Ohta T Fushida S | 2001 | Int J Oncol2001，18，： | 1 |
| 18 | The management of a remnant pancreatic stump for preventing the development of postoperative pancreatic fistulas after distal pancreatectomy: current evidence and our strategy显示文摘 | Isamu Makino Hirohisa Kitagawa Hisatoshi Nakagawara Hidehiro Tajima Itasu Ninomiya Sachio Fushida Takashi Fujimura Tetsuo Ohta | 2013 | Surgery Today2013，，6： | 1 |
| 19 | Serum cytokeratin18 as a biomarker for gastric cancer显示文摘 | Oyama K Fushida S Kinoshita J Okamoto K Makino I Nakamura K | 2013 | Clin Exp Med2013，13，4： | 1 |
| 20 | Lymphangiogenesis and the vascular endothelial growth factor receptor (VEGFR)-3in gastric cancer 显示文摘 | Yonemura Y Fushida S Bando E | 2001 | Eur J Cancer2001，37，7： | 1 |
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