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| 1 | Gilbert's syndrome: High frequency of the (TA)_7 TAA allele in India and its interaction with a novel CAT insertion in promoter of the gene for bilirubin UDP-glucuronosyltransferase 1 gene显示文摘瞄准:在吉伯的症候群(GS ) 在 UDP-glucuronosyltransferase 1 (UGT1A1 ) 基因识别变体并且在印度在正常控制之中在 TA 插入和它的影响的印度,以及频率为 TA 插入和 GS 估计在纯合性之间的协会。方法:95 个 GS 盒子和 95 正常控制被选择。肝工作,另外的测试被做。倡导者和 UGT1A1 基因的所有 5 前 ons 被重新定序。对新奇 trinucleotide 插入的功能的评价被做由在 silico 分析并且由估计 UGT1A1,倡导者活动在 Hep G2 由适当构造的酶记者试金执行了房间线。结果:在 GS 病人之中, 80% 为 TA 插入是同型结合的,它比从另外的种族组的报告高好几倍。吝啬的 UCB 水平与仅仅这插入的一个拷贝在个人之中被提高,它不与有二个拷贝的那些显著地不同。在 UGT1A1 基因的许多新 DNA 变体被发现,包括在倡导者的插入在 GS 病人的一个子集(10%) 发现了的 trinucleotide (猫) ,然而并非在正常之中控制。In-silico 分析证明在倡导者和功能的分析的合拢 DNA 的显著变化在 UGT1A1 基因源于这插入的抄写效率显示出 20 褶层减小,显著地从而提高 UCB 水平。结论:GS 的基因传染病学越过种族组是可变的,在 UGT1A1 倡导者变体之中的上位相互作用调制胆红素 glucuronidation。 | Shabana Farheen Sanghamitra Sengupta Amal Santra Suparna Pal Gopal Krishna Dhali Meenakshi Chakravorty Partha P Majumder Abhijit Chowdhury | 2006 | World Journal of Gastroenterology2006,12,14: | 29 |
| 2 | Sessile serrated adenomas:Demographic,endoscopic and pathological characteristics显示文摘AIM:To study the demographic and endoscopic characteristics of patients with sessile serrated adenoma(SSA) in a single center.METHODS:Patients with SSA were identified by review of the pathology database of Mayo Clinic Arizona from 2005 to 2007.A retrospective chart review was performed to extract data on demographics,polyp characteristics,presence of synchronous adenomatous polyps or cancer,polypectomy methods,and related complications.RESULTS:One hundred and seventy-one(2.9%) of all patients undergoing colonoscopy had a total of 226 SSAs.The mean(SE) size of the SSAs was 8.1(0.4) mm;42% of SSAs were ≤ 5 mm,and 69% were ≤ 9 mm.Fifty-one per cent of SSAs were located in the cecum or ascending colon.Approximately half of the patients had synchronous polyps of other histological types,including hyperplastic and adenomatous polyps.Synchronous adenocarcinoma was present in seven(4%) cases.Ninety-seven percent of polyps were removed by colonoscopy.CONCLUSION:Among patients with colon polyps,2.9% were found to have SSAs.Most of the SSAs were located in the right side and were safely managed by colonoscopy. | Suryakanth R Gurudu Russell I Heigh Giovanni De Petris Evelyn G Heigh Jonathan A Leighton Shabana F Pasha Isaac B Malagon Ananya Das | 2010 | World Journal of Gastroenterology2010,16,27: | 7 |
| 3 | Quercetin modulates iron homeostasis and iNOS expression of splenic macrophages in a rat model of iron deficiency anemia显示文摘Iron deficiency anemia is one of the most common micronutrient deficient conditions around the globe with various consequences,including the weakened immune system.Quercetin is widely distributed bioflavonoid;it has been debated for its dual roles in iron regulation.Quercetin-iron interaction in the body is a complex mechanism which has not been completely understood.The present study aimed to investigate the effect of quercetin on iron supplementation in iron deficiency anemia and on i NOS expression in splenic macrophages.The rat model of iron deficiency anemia was induced by feeding low iron diet to weanling rats for 20 days.The animals were then administered with ferrous sulfate,quercetin,and their combination for 30 days.Blood parameters,histopathological analysis,iron storage,CD68,i NOS and SLC40 expression in rat spleen were investigated.Our results showed that quercetin regulated iron absorption,despite SLC40 down-expression,indicating possible alternate route of iron transport,and that quercetin modulated i NOS production in splenic macrophages.. | Maryam Mazhar Nurul Kabir Shabana U Simjee | 2018 | Chinese Journal of Natural Medicines2018,16,8: | 4 |
| 4 | A review of the role of emerging environmental contaminants in the development of breast cancer in women显示文摘The incidence of breast cancer is on a rise worldwide;it is a disease having a complex etiology.Besides genetics,environmental and other lifestyle factors play a role in the development of the disease.There has been a keen interest in studying associations between breast cancer and exposures to emerging environmental chemicals,which mimic estrogens or influence estrogen levels and signaling in the human body.The common consequence of an endocrine disrupting chemical exposure is that it may have an impact on breast cancer etiology by stimulating formation as well as progression of breast cancer.Exposures to selected emerging environmental contaminants such as alkylphenols(APs),bisphenol A(BPA),parabens,perfluoroalkyl substances(PFASs),phthalates,polybrominated diphenyl ethers(PBDEs),synthetic musks and triclosan,and their probable role in breast cancer development are reviewed.Studies evaluated include the experimental in vitro and in vivo studies as well as human population based studies.In vitro and in vivo evidences indicate that a number of emerging environmental contaminants may play a role in the initiation and/or progression of breast cancer.Although exposures have been assessed in some human populations,breast and other cancer risks associated with these exposures are largely unknown.Efforts should be focussed on the evaluation of these environmental exposures in human populations and their interactions with each other and other genetic and lifestyle risk factors. | Shabana Siddique Cariton Kubwabo Shelley AHarris | 2016 | Emerging Contaminants2016,2,4: | 2 |
| 5 | Endoscopic treatment of anastomotic biliary strictures after deceased donor liver transplantation: outcomes after maximal stent therapy显示文摘 | Shabana F. Pasha M. Edwyn Harrison Ananya Das Cuong C. Nguyen Hugo E. Vargas Vijayan Balan Thomas J. Byrne David D. Douglas David C. Mulligan | 2007 | Gastrointestinal Endoscopy2007,,1: | 2 |
| 6 | Capsule Endoscopy in Patients with Implantable Electromedical Devices is Safe显示文摘 | Lucinda A. Harris Stephanie L. Hansel Elizabeth Rajan Komandoor Srivathsan Robert Rea Michael D. Crowell David E. Fleischer Shabana F. Pasha Suryakanth R. Gurudu Russell I. Heigh Arthur D. Shiff Janice K. Post Jonathan A. Leighton Hsu Heng Yen | 2013 | Gastroenterology Research and Practice2013,,: | 2 |
| 7 | Antibiotic Prophylaxis for Gi Endoscopy显示文摘 | Mouen A. Kashab Ruben D. Acosta David H. Bruining Vinay Chandrasekhara Krishnavel V. Chithadi Mohamad A. Eloubeidi Robert D. Fanelli S.A.G.E.S. Representative Ashley L. Faulx Lisa Fonkalsrud Jenifer R. Lightdale V. Raman Muthusamy Shabana F. Pasha John R. | 2014 | Gastrointestinal Endoscopy2014,,: | 2 |
| 8 | Spot urinary sodium for assessing dietary sodium restriction in cirrhotic ascites显示文摘AIM: To evaluate the accuracy of spot urinary Na/K and Na/creatinine (Cr) ratios as an alternative to 24-h urinary sodium in monitoring dietary compliance in patients with liver cirrhosis and ascites treated with diuretics. METHODS: The study was carried on 40 patients with liver cirrhosis and ascites treated with diuretic therapy. Patients were divided into two groups according to 24-h urinary sodium. We measured spot urine Na/K ratio, Na/ Cr ratio and 24-h urinary sodium. Student's t test was used to compare the interval variables and χ2 test to compare the nominal variables between the two groups. Receiver operator characteristic curve was used to identify the best cutoff point for Na/K and Na/Cr ratio. RESULTS: The best cutoff point for Na/K ratio was 2.5 (P < 0.001) and area under the curve (AUC) was 0.9, and for Na/Cr ratio, the best cutoff point was 35 (P < 0.001) and AUC was 0.885. Na/K ratio showed higher sensitivity and accuracy compared to Na/Cr ratio (87.5% and 87% for Na/K ratio; 81% and 85% for Na/Cr ratio, respectively). CONCLUSION: Spot urine Na/K ratio has adequate accuracy for assessment of dietary sodium restrictioncompared with 24-h urinary sodium in patients with liver cirrhosis and ascites. | Mohammed Abdelhamid El-Bokl Bahaa Eldeen Senousy Khaled Zakaria El-Karmouty Inas El-Khedr Mohammed Sherif Monier Mohammed Sherif Sadek Shabana Hassan Shalaby | 2009 | World Journal of Gastroenterology2009,15,29: | 2 |
| 9 | Double-Balloon Enteroscopy and Capsule Endoscopy Have Comparable Diagnostic Yield in Small-Bowel Disease: A Meta-Analysis显示文摘 | Shabana F. Pasha Jonathan A. Leighton Ananya Das M. Edwyn Harrison G. Anton Decker David E. Fleischer Virender K. Sharma | 2008 | Clinical Gastroenterology and Hepatology2008,,6: | 2 |
| 10 | Double-Balloon Enteroscopy and Capsule Endoscopy Have Comparable Diagnostic Yield in Small-Bowel Disease: A Meta-Analysis显示文摘 | Shabana F. Pasha Jonathan A. Leighton Ananya Das M. Edwyn Harrison G. Anton Decker David E. Fleischer Virender K. Sharma | 2008 | Clinical Gastroenterology and Hepatology2008,,6: | 2 |
| 11 | Application of deformable-body mean axis to flexible muhibody system dynamics 显示文摘 | Agrawal O P Shabana A A | 1956 | Computer Methods in Applied Mechanics and Engineering1956,56,2: | 1 |
| 12 | Splanchnic artery aneurysms显示文摘 | SHABANA F P PETER GLOVICZKL ANTHONY W | | 0,,04: | 1 |
| 13 | Flexible multibody dynamics: Review of past and recent developments显示文摘 | Shabana A A | 1997 | Multibody Sys- tem Dynamics1997,1,: | 1 |
| 14 | A continuous force model for the impact analysis of flexible multibody systems显示文摘 | Khulief Y A Shabana A A | 1987 | Merchanism and Machine Theory1987,22,3: | 1 |
| 15 | Transient analysis of flexible multi-body sys- tems 显示文摘 | Shabana A A | 1986 | Computer Methods in Applied Mechanics and En- gineering1986,54,1: | 1 |
| 16 | A continuous force model for the impact analysis of flexible multibody systems显示文摘 | KHULIEF Y A SHABANA A A | 1987 | Mechanism and Machine Theory1987,22,3: | 1 |
| 17 | 显示文摘 | Shabana Yasser M Wang Gongtao | 2013 | Acta Mech2013,224,6: | 1 |
| 18 | Study of the effect of the spiral geometry on wheel/rail contact forces显示文摘 | SHABANA A A EL-GHANDOUR A I ZAAZAA K E | 2011 | Proceedings of the Institution of Mechanical Engineers Part K: Journal of Multi-Body Dynamics2011,225,2: | 1 |
| 19 | Development of Nonlinear Elastic Leaf Spring Model for MultibodyVehicle Systems显示文摘 | Sugiyama H Shabana A A Omar M A | 2006 | Computer Methods in Applied Mechanics and Engineering2006,195,5051: | 1 |
| 20 | Application of deformable-body mean axis to flexible multibody system dynamics显示文摘 | Agrawal O P Shabana A A | 1986 | Computer Methods in Applied Mechanics and Engineering1986,56,: | 1 |