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| 1 | Pancreatico-biliary endoscopic ultrasound:A systematic review of the levels of evidence,performance and outcomes显示文摘Our aim was to record pancreaticobiliary endoscopic ultrasound(EUS) literature of the past 3 decades and evaluate its role based on a critical appraisal of published studies according to levels of evidence(LE).Original research articles(randomized controlled trials,prospective and retrospective studies),meta-analyses,reviews and surveys pertinent to gastrointestinal EUS were included.All articles published until September 2011 were retrieved from PubMed and classified according to specific disease entities,anatomical subdivisions and therapeutic applications of EUS.The North of England evidencebased guidelines were used to determine LE.A total of 1089 pertinent articles were reviewed.Published research focused primarily on solid pancreatic neoplasms,followed by disorders of the extrahepatic biliary tree,pancreatic cystic lesions,therapeutic-interventional EUS,chronic and acute pancreatitis.A uniform observation in all six categories of articles was the predominance of LE Ⅲ studies followed by LE Ⅳ,Ⅱb,Ⅱa,Ⅰb and Ⅰ a,in descending order.EUS remains the most accurate method for detecting small(< 3 cm) pancreatic tumors,ampullary neoplasms and small(< 4 mm) bile duct stones,and the best test to define vascular invasion in pancreatic and peri-ampullary neoplasms.Detailed EUS imaging,along with biochemical and molecular cyst fluid analysis,improve the differentiation of pancreatic cysts and help predict their malignant potential.Early diagnosis of chronic pancreatitis appears feasible and reliable.Novel imaging techniques(contrast-enhanced EUS,elastography) seem promising for the evaluation of pancreatic cancer and autoimmune pancreatitis.Therapeutic applications currently involve pancreaticobiliary drainage and targeted fine needle injection-guided antitumor therapy.Despite the ongoing development of extra-corporeal imaging modalities,such as computed tomography,magnetic resonance imaging,and positron emission tomography,EUS still holds a leading role in the investigation of the pancreaticobiliary area.The major challenge of EUS evolution is its expanding therapeutic potential towards an effective and minimally invasive management of complex pancreaticobiliary disorders. | Pietro Fusaroli Dimitrios Kypraios Giancarlo Caletti Mohamad A Eloubeidi | 2012 | World Journal of Gastroenterology2012，18，32： | 17 |
| 2 | Endoscopic ultrasound evaluation in the surgical treatment of duodenal and peri-ampullary adenomas显示文摘AIM:To investigate endoscopic ultrasound(EUS) for predicting depth of mucosal invasion and to analyze outcomes following endoscopic and transduodenal resection.METHODS:Records of 111 patients seen at our institution from November 1999 to July 2011 with the postoperative pathological diagnosis of benign ampullary and duodenal adenomas were reviewed.Records of patients who underwent preoperative EUS for diagnostic purposes were identified.The accuracy of EUS in predicting the absence of muscular invasion was assessed by comparing EUS reports to the final surgical pathological results.In addition,the incidence of the post-operative complications over a period of 30 d and the subsequent long-term outcome(recurrence) over a period of 30 mo associated with endoscopic and transduodenal surgical resection was recorded,compared and analyzed.RESULTS:Among 111 patients with benign ampullary and duodenal adenomas,47 underwent preoperative EUS for 29 peri-ampullary lesions and 18 duodenal lesions.In addition,computed tomography was performed in 18 patients,endoscopic retrograde cholangio-pancreatography in 10 patients and esophagogastroduodenoscopy in 22 patients.There were 43 patients with sporadic adenomas and 4 patients with familial adenomatous polyposis(FAP)/other polyposis syndromes.In 38(81%,P < 0.05) patients,EUS reliably identified absence of submucosal and muscularis invasion.In 4 cases,EUS underestimated submucosal invasion that was proven by pathology.In the other 5 patients,EUS predicted muscularis invasion which could not be demonstrated in the resected specimen.EUS predicted tumor muscularis invasion with a specificity of 88% and negative predictive value of 90%(P < 0.05).Types of resection performed included endoscopic resection in 22 cases,partial duodenectomy in 9 cases,transduodenal ampullectomy with sphincteroplasty in 10 cases and pancreaticoduodenectomy in 6 cases.The main post-operative final pathological results included villous adenoma(n = 5),adenoma(n = 8),tubulovillous adenoma(n = 10),tubular adenoma(n = 20) and hyperplastic polyp(n = 2).Among the 47 patients who underwent resection,8(17%,5 of which corresponded to surgical resection) developed post-procedural complications which included retroperitoneal hematoma,intra-abdominal abscess,wound infection,delayed gastric emptying and prolonged ileus.After median followup of 20 mo there were 6 local recurrences(13%,median follow-up = 20 mo) 4 of which were in patients with FAP.CONCLUSION:EUS accurately predicts the depth of mucosal invasion in suspected benign ampullary and duodenal adenomas.These patients can safely undergo endoscopic or local resection. | Lilian C Azih Brett L Broussard Milind A Phadnis Martin J Heslin Mohamad A Eloubeidi Shayam Varadarajulu Juan Pablo Arnoletti | 2013 | World Journal of Gastroenterology2013，19，4： | 13 |
| 3 | Outcomes of EUS-guided drainage of debris-containing pancreatic pseudocysts by using combined endoprosthesis and a nasocystic drain显示文摘 | Ali A. Siddiqui John M. DeWitt Anna Strongin Harkirat Singh Smoker Jordan David E. Loren Thomas Kowalski Mohamad A. Eloubeidi | 2013 | Gastrointestinal Endoscopy2013，，： | 4 |
| 4 | The presence of a cytopathologist increases the diagnostic accuracy of endoscopic ultrasound‐guided fine needle aspiration cytology for pancreatic adenocarcinoma: a meta‐analysis显示文摘 | S. Hébert‐Magee S. Bae S. Varadarajulu J. Ramesh A. R. Frost M. A. Eloubeidi I. A. Eltoum | 2013 | Cytopathology2013，，3： | 4 |
| 5 | Screening for hepatocellular carcinoma in patients with hepatitis C cirrhosis: a cost-utility analysis显示文摘 | Miguel R Arguedas Victor K Chen Mohamad A Eloubeidi Michael B Fallon | 2003 | The American Journal of Gastroenterology2003，，3： | 3 |
| 6 | Patients With Obstructive Jaundice and Biliary Stricture±Mass Lesion on Imaging: Prevalence of Malignancy and Potential Role of EUS-FNA显示文摘 | Pavan Tummala Satish Munigala Mohamad A. Eloubeidi Banke Agarwal | 2013 | Journal of Clinical Gastroenterology2013，，6： | 3 |
| 7 | Histologic and Imaging Features of Mural Nodules in Mucinous Pancreatic Cysts显示文摘 | Ning Zhong Lizhi Zhang Naoki Takahashi Vladislav Shalmiyev Marcia Irene Canto Jonathan E. Clain John C. Deutsch John DeWitt Mohamad A. Eloubeidi Ferga C. Gleeson Michael J. Levy Shawn Mallery Massimo Raimondo Elizabeth Rajan Tyler Stevens Mark Topazian | 2012 | Clinical Gastroenterology and Hepatology2012，，2： | 2 |
| 8 | Antibiotic Prophylaxis for Gi Endoscopy显示文摘 | Mouen A. Kashab Ruben D. Acosta David H. Bruining Vinay Chandrasekhara Krishnavel V. Chithadi Mohamad A. Eloubeidi Robert D. Fanelli S.A.G.E.S. Representative Ashley L. Faulx Lisa Fonkalsrud Jenifer R. Lightdale V. Raman Muthusamy Shabana F. Pasha John R. | 2014 | Gastrointestinal Endoscopy2014，，： | 2 |
| 9 | ERCP-Related Perforations: Risk Factors and Management显示文摘 | R. Enns M. Eloubeidi K. Mergener P. Jowell M. Branch T. Pappas J. Baillie | 2002 | Endoscopy2002，，04： | 2 |
| 10 | EUS-guided FNA of the left adrenal gland in patients with thoracic or GI malignancies显示文摘 | Eloubeidi MA Seewald S Tamhane A | 2004 | Gastrointest Endosc2004，59，6： | 1 |
| 11 | Predictors of survival for esophageal cancer patients with and without celiac axis lymphadenopathy: impact of staging endosonography显示文摘 | Mohamad A Eloubeidi Michael B Wallace Brenda J Hoffman Margaret B Leveen Annette Van Velse Robert H Hawes Carolyn E Reed | 2001 | The Annals of Thoracic Surgery2001，，1： | 1 |
| 12 | Endoscopic ultrasound-guided fine needle aspiration of mediastinal lymph node in patients with suspected lung cancer after positron emission tomography and computed tomography scans 显示文摘 | Eloubeidi MA Cerfolio R J Chen VK | 2005 | Ann Thorac Surg2005，79，： | 1 |
| 13 | Yield of EUS-guided FNA of pancreatic masses in the presence or the absence of chronic pancreatitis 显示文摘 | Varadarajulu S Tamhane A Eloubeidi MA | 2005 | Gastrointest Endos2005，62，5： | 1 |
| 14 | ERCP-related perforations: risk factors and management显示文摘 | Enns R Eloubeidi MA Mergener K | 2002 | Endoscopy2002，34，4： | 1 |
| 15 | Diagnosis of gastrointestinal tract Lesions by endoscopic ultrasound-guided fine-needle aspiration biopsy显示文摘 | Vander Noot MR 3rd Eloubeidi MA Chen VK | 2004 | Cancer2004，102，3： | 1 |
| 16 | Diagnosis of gastrointestinal tract lesions by endoscopic ultrasoudn-guided fineneedle aspiration biopsy显示文摘 | Vander Noot MR 3rd Eloubeidi MA chen VK | 2004 | cancer2004，102，： | 1 |
| 17 | A prospective evaluation of an algorithm incorporating routine preoperative endoscopic ultrasound-guided fine needle aspiration in suspected pancreatic cancer 显示文摘 | Eloubeidi MA Varadarajulu S Desai S | 2007 | J Gastrointest Surg2007，11，7： | 1 |
| 18 | Impact of EUS in the evaluation of pancreaticobiliary disorders in children 显示文摘 | Varadarajulu S Wilcox CM Eloubeidi MA | 2005 | Gastrointest Endosc2005，62，2： | 1 |
| 19 | The dignosis of gastrointestinal tract lesion by endoscopic ultrasoundguided fine-needle aspiration biopsy 显示文摘 | Vander Noot M R 3rd Eloubeidi M A Chen V K | 2004 | Cancer2004，102，3： | 1 |
| 20 | Fine needle aspirafionbiopsy of the islet cell tumor of pancreas: a comparison betweecomputerized axial tomography and endoscopic ultrasound-guided fine needle aspiration biopsy显示文摘 | JHALA D ELOUBEIDI M CHHIENG DC | 2002 | Ann Diagn Pathol2002，6，： | 1 |
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