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| 1 | Dendritic cell-based immunotherapy显示文摘用树枝状的房间(DC ) 的免疫疗法基于种痘是为利用病人自己的潜力的一条同意的途径在变形荷尔蒙倔强的癌症消除肿瘤房间的免疫系统。尽管许多 DC 疫苗在诊所,并且在与临床的结果联系的一些情况中被测试了并且证明产生免疫性,外套在那里不仍然是怎么生产 DC 疫苗上的一致。能在我们将讨论什么从临床的研究关于人的 DC 生物学远这样被了解了,并且来临怎么当前在诊所使用 DC 疫苗的这评论被改进提高反肿瘤免疫。 | Rachel L Sabado Sreekumar Balan Nina Bhardwaj | 2017 | Cell Research2017，27，1： | 63 |
| 2 | 5-Azacytidine induces changes in electrophysiological properties of human mesenchymal stem cells显示文摘以前,导出髓的干细胞(MSC ) 与不确定的脱氧核糖核酸甲基转移酶禁止者 5-azacytidine 对待的老鼠骨头被报导区分 intocardiomyocytes。现在的学习的目的是在从健康骨髓施主获得的人的单音的原子房间调查类似的区别策略的效率。After1-3 段落,文化为 24 h 暴露于到 6 星期进一步的文化跟随的 5-azacytidine (3 mciroM ) 。药处理没导致 myogenic 标记 MyoD 或心脏的 markersNkx2.5 和 GATA-4 的表示并且没在后续期间产出跳动的房间。在补丁夹钳实验,近似 10-15% 对待,未经治疗的房间展出了 L 类型 Ca (2+) 水流。几乎所有房间表面地出现了修正快速或慢的激活动力学的 K (+) 水流。在与匹配时间的控制相比在 6 星期处理以后加倍的 +60 mV 意味着当前的振幅。对待的房间的 Membranecapacitance 比在在处理以后的 controls2 星期内显著地大并且在 6 个星期以后仍然保持高。为 K (+) 隧道 Kv1.1, Kv1.5, Kv2.1, Kv4.3 和 KCNMA1 并且为 Ca (2+) 隧道 Ca (v) 的 mRNAs 的表示层次 1.2 没被 5-azacytidine 影响。在以前显示出禁止 hMSC 的快速或慢慢地激活的 K (+) 水流的集中的 Treatmentwith 钾隧道块 ers tetraethylammonium 和 clofilium 禁止了这些房间的增长。我们的结果建议尽管有进 cardiomyocytes 的 hMSC 的区别的缺席,有 5-azacytidine 的处理在当前的密度引起了深刻变化。 | Bartosz Balanal Cecilia Nicoletti Ihor Zahanich Eva M Graf Torsten Christ Sabine Boxberger Ursula Ravens | 2006 | Cell Research2006，16，12： | 20 |
| 3 | 喷丸强化技术的应用显示文摘随用户对于汽车性能要求的逐步提高,汽车零部件面临着削减重量、延长寿命的双重压力。采用合理的表面处理工艺,可以有效地解决上述问题。 | Kumar Balan | 2008 | 金属加工(热加工)2008，，19： | 8 |
| 4 | Epidermal stem cells and skin tissue engineering in hair follicle regeneration显示文摘The reconstitution of a fully organized and functional hair follicle from dissociated cells propagated under defined tissue culture conditions is a challenge stillpending in tissue engineering. The loss of hair follicles caused by injuries or pathologies such as alopecia not only affects the patients' psychological well-being, but also endangers certain inherent functions of the skin. It is then of great interest to find different strategies aiming to regenerate or neogenerate the hair follicle under conditions proper of an adult individual. Based upon current knowledge on the epithelial and dermal cells and their interactions during the embryonic hair generation and adult hair cycling, many researchers have tried to obtain mature hair follicles using different strategies and approaches depending on the causes of hair loss. This review summarizes current advances in the different experimental strategies to regenerate or neogenerate hair follicles, with emphasis on those involving neogenesis of hair follicles in adult individuals using isolated cells and tissue engineering. Most of these experiments were performed using rodent cells, particularly from embryonic or newborn origin. However, no successful strategy to generate human hair follicles from adult cells has yet been reported. This review identifies several issues that should be considered to achieve this objective. Perhaps the most important challenge is to provide threedimensional culture conditions mimicking the structure of living tissue. Improving culture conditions that allow the expansion of specific cells while protecting their inductive properties, as well as methods for selecting populations of epithelial stem cells, should give us the necessary tools to overcome the difficulties that constrain human hair follicle neogenesis. An analysis of patent trends shows that the number of patent applications aimed at hair follicle regeneration and neogenesis has been increasing during the last decade. This field is attractive not only to academic researchers but also to the companies that own almost half of the patents in this field. | María Eugenia Balaná Hernán Eduardo Charreau Gustavo Jose Leirós | 2015 | World Journal of Stem Cells2015，7，4： | 7 |
| 5 | Sequencing a Juglans regia×J.microcarpa hybrid yields high-quality genome assemblies of parental species显示文摘Members of the genus Juglans are monecious wind-pollinated trees in the family Juglandaceae with highly heterozygous genomes,which greatly complicates genome sequence assembly.The genomes of interspecific hybrids are usually comprised of haploid genomes of parental species.We exploited this attribute of interspecific hybrids to avoid heterozygosity and sequenced an interspecific hybrid Juglans microcarpa×J.regia using a novel combination of single-molecule sequencing and optical genome mapping technologies.The resulting assemblies of both genomes were remarkably complete including chromosome termini and centromere regions.Chromosome termini consisted of arrays of telomeric repeats about 8 kb long and heterochromatic subtelomeric regions about 10 kb long.The centromeres consisted of arrays of a centromere-specific Gypsy retrotransposon and most contained genes,many of them transcribed.Juglans genomes evolved by a whole-genome-duplication dating back to the Cretaceous-Paleogene boundary and consist of two subgenomes,which were fractionated by numerous short gene deletions evenly distributed along the length of the chromosomes.Fractionation was shown to be asymmetric with one subgenome exhibiting greater gene loss than the other.The asymmetry of the process is ongoing and mirrors an asymmetry in gene expression between the subgenomes.Given the importance of J.microcarpa×J.regia hybrids as potential walnut rootstocks,we catalogued disease resistance genes in the parental genomes and studied their chromosomal distribution.We also estimated the molecular clock rates for woody perennials and deployed them in estimating divergence times of Juglans genomes and those of other woody perennials. | Tingting Zhu Le Wang Frank M.You Juan C.Rodriguez Karin R.Deal Limin Chen Jie Li Sandeep Chakraborty Bipin Balan Cai-Zhong Jiang Patrick J.Brown Charles ALeslie Mallikarjuna KAradhya Abhaya M.Dandekar Patrick E.McGuire Daniel Kluepfel Jan Dvorak Ming-Cheng Luo | 2019 | Horticulture Research2019，6，1： | 7 |
| 6 | Evidence-Based Incorporation of Serum Sodium Concentration Into MELD显示文摘 | Scott W. Biggins W. Ray Kim Norah A. Terrault Sammy Saab Vijay Balan Thomas Schiano Joanne Benson Terry Therneau Walter Kremers Russell Wiesner Patrick Kamath Goran Klintmalm | 2006 | Gastroenterology2006，，6： | 3 |
| 7 | Split-dose or hybrid nonsteroidal anti-inflammatory drugs and Nacetylcysteine therapy for prevention of post-retrograde cholangiopancreatography pancreatitis显示文摘BACKGROUND Despite significant technical and training improvements, the incidence of postendoscopic retrograde cholangiopancreatography(ERCP) pancreatitis(PEP) has not significantly dropped. Although many studies have evaluated the efficacy of various agents, e.g. nonsteroidal anti-inflammatory drugs, octreotide,antioxidants, administered via various dosages, routes(oral, intrarectal or parenteral), and schedules(before or after the procedure), the results have been conflicting.AIM To evaluate efficacy of three pharmacologic prophylactic methods for prevention of PEP.METHODS In this prospective, single-center randomized trial, patients who underwent firsttime ERCP for choledocholithiasis were randomly assigned to three groups. The first group received 600 mg N-acetylcysteine 15 min prior to ERCP, and perrectum administration of 50 mg indomethacin both prior to and after completion of the ERCP. The second group was administered only the 50 mg indomethacin per-rectum both prior to and after the ERCP. The third group was administeredper-rectum 100 mg indomethacin only after the ERCP, representing the control group given the guideline-recommended regimen. The primary end-point was PEP prevention.RESULTS Among the total 211 patients evaluated during the study, 186 fulfilled the inclusion criteria and completed the protocol. The percentages of patients who developed PEP in each of the three groups were not significantly different(χ2 =2.793, P = 0.247). Among the acute PEP cases, for all groups, 14 patients developed mild pancreatitis(77.77%) and 4 moderate. No severe cases of PEP occurred, and in all PEP cases the resolution was favorable. No adverse events related to the medications(digestive hemorrhage, rectal irritation, or allergies)occurred.CONCLUSION The efficacies of split-dose indomethacin and combined administration(Nacetylcysteine with indomethacin) for preventing PEP were similar to that of the standard regimen. | Laura Pavel Gheorghe Gh Balan Alexandra Nicorescu Georgiana Emmanuela Gilca-Blanariu Catalin Sfarti Stefan Chiriac Smaranda Diaconescu Vasile Liviu Drug Gheorghe Balan Gabriela Stefanescu | 2019 | World Journal of Clinical Cases2019，7，3： | 3 |
| 8 | 玉米秸秆水解残渣厌氧消化的产气性能显示文摘为了考察玉米秸秆水解残渣(Unhydrolyzed solid,UHS)的厌氧消化产甲烷潜力,研究了接种物类型、接种比例以及发酵温度对UHS产气性能的影响。结果表明,餐厨垃圾厌氧消化液作为接种物时,UHS具有较高的产气能力,累积甲烷产量达到208.06 m L·g^(-1)VS;UHS的累积甲烷产量与接种物对底物的比值(Inoculum to substrate ratios,RI/S)有关,其值随着接种比例的减小而逐渐降低,当接种比例RI/S为0.1∶1~3∶1时,累积甲烷产量为111.20~224.48 m L·g^(-1)VS,UHS的生物降解率为27.89%~56.29%,其降解能力随着底物浓度的升高而降低;在高温发酵(55℃)和中温发酵(35℃)条件下,相同接种比例的对照组中,UHS累积甲烷产量较为接近,但高温发酵的产气速率明显高于中温发酵。 | 陈世平 汤晓玉 肖泽仪 王文国 尹小波 VENKATESH Balan 吴波 胡启春 | 2016 | 农业环境科学学报2016，35，3： | 3 |
| 9 | A brief review of equatorial ionization anomaly and ionospheric irregularities显示文摘Following a brief history and progress of ionospheric research, this paper presents a brief review of the recent developments in the understanding of two major phenomena in low and mid latitude ionosphere—the equatorial ionization anomaly(EIA) and involved equatorial plasma fountain(EPF) and ionospheric irregularities. Unlike the easy-to-understand misinterpretations, the EPF involves field perpendicular E×B plasma drift and field-aligned plasma diffusion acting together and plasma flowing in the direction of the resultant at all points along the field lines at all altitudes. The EIA is formed mainly from the removal of plasma from around the equator by the upward E×B drift creating the trough and consequently the crests with small accumulation of plasma at the crests when the crests are within ~±20° magnetic latitudes and no accumulation when they are beyond ~±25° magnetic latitudes. The strong EIA under magnetically active conditions arises from the simultaneous impulsive action of eastward prompt penetration electric field and equatorward neutral wind. Intense ionospheric irregularities develop in the post-sunset bottom-side equatorial ionosphere when it rises to high altitudes, and evolve nonlinearly into the topside. Pre-reversal enhancement(PRE) of the vertical upward E×B drift and its fluctuations amplified during PRE provide the driving force and seed, with neutral wind and gravity waves being the primary sources. At low solar activity especially in summer when fast varying PRE is absent, the slow varying gravity waves including large scale waves(LSW)seem to act as both driver and seed for weak irregularities. At mid latitudes, the irregularities are weak and associated with medium scale traveling ionospheric disturbances(MSTIDs). A low latitude minimum in the occurrence of the irregularities at March equinox predicted by theoretical models is identified. The minimum occurs on the poleward side of the EIA crest and shifts equatorward from ~25° magnetic latitudes at high solar activity to below 17° at low solar activity. | Nanan Balan LiBo Liu HuiJun Le | 2018 | Earth and Planetary Physics2018，2，4： | 3 |
| 10 | Modeling carbon footprints across the supply chain显示文摘 | Balan Sundarakani Robert de Souza Mark Goh Stephan M. Wagner Sushmera Manikandan | 2010 | International Journal of Production Economics2010，，： | 2 |
| 11 | 喷丸技术在齿轮表面强化中的应用显示文摘目前,汽车制造业已普遍利用喷丸强化工艺来提高传动零部件的使用寿命。通常情况下,零件在热处理后进行喷丸强化,对于一些关键零件,如齿圈和行星齿轮等,强化是生产的最后一道工序。 | Kumar Balan | 2008 | 金属加工(热加工)2008，，17： | 2 |
| 12 | Endoscopic treatment of anastomotic biliary strictures after deceased donor liver transplantation: outcomes after maximal stent therapy显示文摘 | Shabana F. Pasha M. Edwyn Harrison Ananya Das Cuong C. Nguyen Hugo E. Vargas Vijayan Balan Thomas J. Byrne David D. Douglas David C. Mulligan | 2007 | Gastrointestinal Endoscopy2007，，1： | 2 |
| 13 | 不同株行距和树形对高密度栽植樱桃产量的影响显示文摘优质樱桃的生产取决于品种、砧木、栽植密度、树形、树势、树龄、果实着生位置、果树负载量、农药和生长调节剂的使用等环境因素和农业技术管理措施。在樱桃的栽培管理中,应选择正确的授粉品种结合适合的砧木、树形和栽培密度。摩尔多瓦共和国的气候条件非常适合樱桃高密度栽培,但现在很多樱桃果园仍然是传统栽培模式。摩尔多瓦共和国政府为建立现代樱桃园的果农提供有吸引力的补贴,鼓励选择适宜的品种、砧木和树形,以实现果园现代化生产。 | Igor IVANOV Valerian BALAN Ananie PE?TEANU Sergiu VAMA?ESCU Petru BALAN Vasile ?ARBN 赵慧 | 2019 | 烟台果树2019，0，3： | 2 |
| 14 | Chlamydia host cell interactions : recent advances on bacterial entry and intracellular development显示文摘 | Dautry-Varsat A Balan ME Wyplosz B | 2004 | Traffic2004，5，8： | 1 |
| 15 | An analysis of the in vitro and in vivo phenotypes of mutants of herpes simplex virus type 1 lacking glycoproteins gG, gE, gIor the putative gJ显示文摘 | Balan P Davis-Poynter N Bell S | 1994 | J Gen Virol1994，75，6： | 1 |
| 16 | Metamictization and chemical durability of detrital zircon显示文摘 | BALAN E DANIEL R N PATRICK T | 2001 | Am Mineral2001，86，： | 1 |
| 17 | Ethanolic fermentation of hydroly- sates from ammonia fiber expansion ( AFEX) treated com stover and distillers grain without detoxification and external nutrient supplementation显示文摘 | Lau M W Dale B E Balan V | 2008 | Biotechnology and bioengineering2008，99，3： | 1 |
| 18 | HIV knowledge and beliefs among men who have sex with men(MSM)in Buenos Aires,Argentina显示文摘 | Pando MA Balan I Marone R | 2013 | AIDS Behav2013，17，4： | 1 |
| 19 | Fast NMRjuice identification based on sugars and other plant metabolites fromfruits显示文摘 | BALAN M NIOCOLESCU A STAVARACHE C | 2013 | Revue Roumaine de Chimie2013，58，23： | 1 |
| 20 | Safety and antiviral activity of albinterferon alfa-2b in prior interferon nonresponders with chronic hepatitis C显示文摘 | Nelson DR Rustgi V Balan V | 2009 | Clin Gastroenterol Hepatol2009，7，2： | 1 |
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