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| 1 | The importance of glutathione and phytochelatins on the selenite and arsenate detoxification in Arabidopsis thaliana显示文摘We investigated the role of glutathione(GSH) and phytochelatins(PCs) on the detoxification of selenite using Arabidopsis thaliana. The wild-type(WT) of Arabidopsis thaliana and its mutants(glutathione deficient Cad 2–1 and phytochelatins deficient Cad 1–3) were separately exposed to varying concentrations of selenite and arsenate and jointly to both toxicants to determine their sensitivities. The results of the study revealed that, the mutants were about 20-fold more sensitive to arsenate than the WT, an indication that the GSH and PCs affect arsenate detoxification. On the contrary, the WT and both mutants showed a similar level of sensitivity to selenite, an indication that the GSH and PCs do not significantly affect selenite detoxification. However, the WT is about 8 times more sensitive to selenite than to arsenate, and the mutants were more resistant to selenite than arsenate by a factor of 2. This could not be explained by the accumulation of both elements in roots and shoots in exposure experiments. The co-exposure of the WT indicates a synergistic effect with regards to toxicity since selenite did not induce PCs but arsenic and selenium compete in their PC binding as revealed by speciation analysis of the root extracts using HPLC–ICP–MS/ESI–MS. In the absence of PCs an antagonistic effect has been detected which might suggest indirectly that the formation of Se glutathione complex prevent the formation of detrimental selenopeptides. This study, therefore, revealed that PC and GSH have only a subordinate role in the detoxification of selenite. | Fatai Adigun Aborode Andrea Raab Matthias Voigt Leticia Malta Costa Eva M.Krupp Joerg Feldmann | 2016 | Journal of Environmental Sciences2016，28，11： | 6 |
| 2 | The estimation of the digestibility and metabolizable energy content of ruminant feedingstuffs from the gas production when they are incubated with rumen liquor in vitro显示文摘 | K. H. Menke L. Raab A. Salewski H. Steingass D. Fritz W. Schneider | 1979 | The Journal of Agricultural Science1979，，： | 4 |
| 3 | Effects of sleep bruxism on functional and occlusal parameters:a prospective controlled investigation显示文摘This study was conducted to verify the results of a preceding retrospective pilot study by means of a prospective controlled investigation including a larger sample size.Therefore,the aim of this clinical investigation was to analyze the relationship between sleep bruxism and several functional and occlusal parameters.The null hypothesis of this study was that there would be no differences among sleep bruxism subjects and non-sleep bruxism controls regarding several functional and occlusal parameters.Fifty-eight sleep bruxism subjects and 31 controls participated in this study.The diagnosis sleep bruxism was based on clinical criteria of the American Academy of Sleep Medicine.Sixteen functional and occlusal parameters were recorded clinically or from dental study casts.Similar to the recently published retrospective pilot study,with a mean slide of 0.77 mm(s.d.,0.69 mm) in the sleep bruxism group and a mean slide of 0.4 mm(s.d.,0.57 mm) in the control group,the evaluation of the mean comparison between the two groups demonstrated a larger slide from centric occlusion to maximum intercuspation in sleep bruxism subjects(Mann-Whitney U-test;P50.008).However,following Bonferroni adjustment,none of the 16 occlusal and functional variables differed significantly between the sleep bruxism subjects and the non-sleep bruxism controls.The present study shows that the occlusal and functional parameters evaluated do not differ between sleep bruxism subjects and non-sleep bruxism subjects.However,as the literature reveals a possible association between bruxism and certain subgroups of temporomandibular disorders,it appears advisable to incorporate the individual adaptive capacity of the stomatognathic system into future investigations. | Michelle Alicia Ommerborn Maria Giraki Christine Schneider Lars Michael Fuck Jrg Handschel Matthias Franz Wolfgang Hans-Michael Raab Ralf Schfer | 2012 | International Journal of Oral Science2012，4，3： | 4 |
| 4 | Tumour response and secondary resectability of colorectal liver metastases following neoadjuvant chemotherapy with cetuximab: the CELIM randomised phase 2 trial显示文摘 | Gunnar Folprecht Thomas Gruenberger Wolf O Bechstein Hans-Rudolf Raab Florian Lordick J?rg T Hartmann Hauke Lang Andrea Frilling Jan Stoehlmacher Jürgen Weitz Ralf Konopke Christian Stroszczynski Torsten Liersch Detlev Ockert Thomas Herrmann Eray Goekkurt | 2010 | Lancet Oncology2010，，1： | 3 |
| 5 | Overview of constitutive laws, kinematics, homogenization and multiscale methods in crystal plasticity finite-element modeling: Theory, experiments, applications显示文摘 | F. Roters P. Eisenlohr L. Hantcherli D.D. Tjahjanto T.R. Bieler D. Raabe | 2009 | Acta Materialia2009，，4： | 3 |
| 6 | Preoperative chemoradiotherapy and postoperative chemotherapy with fluorouracil and oxaliplatin versus fluorouracil alone in locally advanced rectal cancer: initial results of the German CAO/ARO/AIO-04 randomised phase 3 trial显示文摘 | Claus R?del Torsten Liersch Heinz Becker Rainer Fietkau Werner Hohenberger Torsten Hothorn Ullrich Graeven Dirk Arnold Marga Lang-Welzenbach Hans-Rudolf Raab Heiko Sülberg Christian Wittekind Sergej Potapov Ludger Staib Clemens Hess Karin Weigang-K?hler G | 2012 | Lancet Oncology2012，，7： | 2 |
| 7 | Triple therapy in treatment-experienced patients with HCV-cirrhosis in a multicentre cohort of the French Early Access Programme (ANRS CO20-CUPIC) – NCT01514890<!-- Doctopic: VH -->显示文摘 | Christophe Hézode Hélène Fontaine Céline Dorival Dominique Larrey Fabien Zoulim Valérie Canva Victor de Ledinghen Thierry Poynard Didier Samuel Marc Bourlière Jean-Pierre Zarski Jean-Jacques Raabe Laurent Alric Patrick Marcellin Ghassan Riachi Pierre-Henr | 2013 | Journal of Hepatology2013，，： | 2 |
| 8 | Acoustic tomographic imaging of temperature and flow fields in air显示文摘 | Manuela Barth Armin Raabe | 2011 | Measurement Science and Technology2011，，3： | 2 |
| 9 | Segregation-assisted spinodal and transient spinodal phase separation at grain boundaries显示文摘Segregation to grain boundaries affects their cohesion,corrosion,and embrittlement and plays a critical role in heterogeneous nucleation.In order to quantitatively study segregation and low-dimensional phase separation at grain boundaries,here,we apply a density-based phase-field model.The current model describes the grain-boundary thermodynamic properties based on available bulk thermodynamic data,while the grain-boundary-density profile is obtained using atomistic simulations.To benchmark the performance of the model,Mn grain-boundary segregation in the Fe–Mn system is studied.3D simulation results are compared against atom probe tomography measurements conducted for three alloy compositions.We show that a continuous increase in the alloy composition results in a discontinuous jump in the segregation isotherm.The jump corresponds to a spinodal phase separation at grain boundary.For alloy compositions above the jump,we reveal an interfacial transient spinodal phase separation.The transient spinodal phenomenon opens opportunities for knowledge-based microstructure design through the chemical manipulation of grain boundaries.The proposed density-based model provides a powerful tool to study thermodynamics and kinetics of segregation and phase changes at grain boundaries. | Reza Darvishi Kamachali Alisson Kwiatkowski da Silva Eunan McEniry Dirk Ponge Baptiste Gault Jörg Neugebauer Dierk Raabe | 2020 | npj Computational Materials2020，，1： | 2 |
| 10 | On the formation and growth of intermetallic phases during interdiffusion between low-carbon steel and aluminum alloys显示文摘 | H. Springer A. Kostka E.J. Payton D. Raabe A. Kaysser-Pyzalla G. Eggeler | 2010 | Acta Materialia2010，，4： | 2 |
| 11 | TEXTURE AND CRYSTALLINITY EVOLUTION IN ISOTACTIC POLYPROPYLENE INDUCED BY ROLLING AND THEIR INFLUENCE ON MECHANICAL PROPERTIES显示文摘The orientation and crystallinity evolution of isotactic polypropylene (iPP) induced by rolling were studied using wide angle X-ray scattering with an area detector. The tensile mechanical properties of rolled isotactic polypropylene sheets were also measured in this work. The texture component method was used to analyze the rolling texture. The rolling texture consists mainly of (010)[001], (130)[001] and [001]//RD fiber components in the sample with a rolling true strain of 1.5. The results reveal that crystallinity drastically decreases during rolling. It is suggested that amorphization is a deformation mechanism which takes place as an alternative to crystallographic intralamellar slip depending on the orientation of the lamellae. Both the orientation and crystallinity affect the tensile mechanical properties of rolled polypropylene. Crystallinity influences the elastic modulus on both directions and yield strength on transverse direction at the first stage of deformation. Orientation is the main reason for the changes of mechanical properties, especially at the latter part of deformation. The changes of both tensile strength and elongation percentage on rolling direction are larger than those on transverse direction, which results from the orientation. At last, the anisotropic mechanical properties occur on the rolling and transverse direction: high tensile strength with low elongation percentage on rolling direction and low tensile strength with high elongation percentage on transverse direction. | Dierk Raabe 贾涓 | 2006 | Chinese Journal of Polymer Science2006，24，4： | 2 |
| 12 | Bypass versus Angioplasty in Severe Ischaemia of the Leg (BASIL) trial: A survival prediction model to facilitate clinical decision making显示文摘 | Andrew W. Bradbury Donald J. Adam Jocelyn Bell John F. Forbes F. Gerry R. Fowkes Ian Gillespie Charles Vaughan Ruckley Gillian M. Raab | 2010 | Journal of Vascular Surgery2010，，： | 2 |
| 13 | Teaching solid mechanics to artificial intelligence—a fast solver for heterogeneous materials显示文摘We propose a deep neural network(DNN)as a fast surrogate model for local stress calculations in inhomogeneous non-linear materials.We show that the DNN predicts the local stresses with 3.8%mean absolute percentage error(MAPE)for the case of heterogeneous elastic media and a mechanical contrast of up to factor of 1.5 among neighboring domains,while performing 103 times faster than spectral solvers.The DNN model proves suited for reproducing the stress distribution in geometries different from those used for training.In the case of elasto-plastic materials with up to 4 times mechanical contrast in yield stress among adjacent regions,the trained model simulates the micromechanics with a MAPE of 6.4%in one single forward evaluation of the network,without any iteration.The results reveal an efficient approach to solve non-linear mechanical problems,with an acceleration up to a factor of 8300 for elastic-plastic materials compared to typical solvers. | Jaber Rezaei Mianroodi Nima H.Siboni Dierk Raabe | 2021 | npj Computational Materials2021，，1： | 2 |
| 14 | Serum S-100 and neuron specific enolase for prediction of regaining consciousness after global cerebral ischemia 显示文摘 | Martens P Raabe A Johnsson P | 1998 | Stroke1998，29，11： | 2 |
| 15 | Three-dimensional rotational angiography guidance for aneurysm surgery 显示文摘 | Raabe A Beck J Rohde S | 2006 | J Neurosurg2006，105，3： | 1 |
| 16 | Theory-guided bottom- up design of β-titanium alloys as biomaterials based on first principles calculations: Theory and experiments 显示文摘 | Raabe D Sander B Fridk M | 2007 | Acta Mater2007，55，13： | 1 |
| 17 | Preconditions to ground based GPS water vapour tomography显示文摘 | Bender M and Raabe A | 2007 | Annales Geophysicae2007，25，8： | 1 |
| 18 | Textures of Strip Cast and Hot Rolled Ferritie and Austenitic Stainless Steel 显示文摘 | Raabe D | 1995 | Material Science Technology1995，11，5： | 1 |
| 19 | Determination of 18 nucleobases, nucleosides and nucleotides in human peripheral blood mononuclear cells by isocratic solvent-generated ion-pair chromatogra- phy 显示文摘 | Margit Cichna Heide Daxecker Markus Raab | 2003 | Analytica ChimicaActa2003，481，2： | 1 |
| 20 | Measurements of serum S-100B protein:effects of storage time and temperature on pre- analytical stability 显示文摘 | Raabe A Kopetsch O Gross U | 2003 | Clin Chem Lab Med2003，41，5： | 1 |
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