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| 1 | The importance of glutathione and phytochelatins on the selenite and arsenate detoxification in Arabidopsis thaliana显示文摘We investigated the role of glutathione(GSH) and phytochelatins(PCs) on the detoxification of selenite using Arabidopsis thaliana. The wild-type(WT) of Arabidopsis thaliana and its mutants(glutathione deficient Cad 2–1 and phytochelatins deficient Cad 1–3) were separately exposed to varying concentrations of selenite and arsenate and jointly to both toxicants to determine their sensitivities. The results of the study revealed that, the mutants were about 20-fold more sensitive to arsenate than the WT, an indication that the GSH and PCs affect arsenate detoxification. On the contrary, the WT and both mutants showed a similar level of sensitivity to selenite, an indication that the GSH and PCs do not significantly affect selenite detoxification. However, the WT is about 8 times more sensitive to selenite than to arsenate, and the mutants were more resistant to selenite than arsenate by a factor of 2. This could not be explained by the accumulation of both elements in roots and shoots in exposure experiments. The co-exposure of the WT indicates a synergistic effect with regards to toxicity since selenite did not induce PCs but arsenic and selenium compete in their PC binding as revealed by speciation analysis of the root extracts using HPLC–ICP–MS/ESI–MS. In the absence of PCs an antagonistic effect has been detected which might suggest indirectly that the formation of Se glutathione complex prevent the formation of detrimental selenopeptides. This study, therefore, revealed that PC and GSH have only a subordinate role in the detoxification of selenite. | Fatai Adigun Aborode Andrea Raab Matthias Voigt Leticia Malta Costa Eva M.Krupp Joerg Feldmann | 2016 | Journal of Environmental Sciences2016，28，11： | 6 |
| 2 | Tumour response and secondary resectability of colorectal liver metastases following neoadjuvant chemotherapy with cetuximab: the CELIM randomised phase 2 trial显示文摘 | Gunnar Folprecht Thomas Gruenberger Wolf O Bechstein Hans-Rudolf Raab Florian Lordick J?rg T Hartmann Hauke Lang Andrea Frilling Jan Stoehlmacher Jürgen Weitz Ralf Konopke Christian Stroszczynski Torsten Liersch Detlev Ockert Thomas Herrmann Eray Goekkurt | 2010 | Lancet Oncology2010，，1： | 3 |
| 3 | High CW power using an external cavity for spectral beam combining of diode laser-bar emission显示文摘 | Andreas Jechow Volker Raab Ralf Menzel | 2006 | Appl Opt2006，45，15： | 1 |
| 4 | Histological evidence of delayed ischemic brain tissue damage in the rat double-hemorrhage model显示文摘 | Erdem Güresir Andreas Raabe Alongkorn Jaiimsin Santosh Dias Peter Raab Volker Seifert Hartmut Vatter | 2010 | Journal of the Neurological Sciences2010，，1： | 1 |
| 5 | PERSISTENCE OF THE NITRIC OXIDE-DEPENDENT VASODILATOR PATHWAY OF CEREBRAL VESSELS AFTER EXPERIMENTAL SUBARACHNOID HEMORRHAGE显示文摘 | Hartmut Vatter Stefan Weidauer Santos Dias Christine Preibisch Sumbele Ngone Andreas Raabe Michael Zimmermann Volker Seifert | 2007 | Neurosurgery2007，，1： | 1 |
| 6 | Preventing Vasospasm Improves Outcome After Aneurysmal Subarachnoid Hemorrhage: Rationale and Design of CONSCIOUS-2 and CONSCIOUS-3 Trials显示文摘 | R. Loch Macdonald Randall T. Higashida Emanuela Keller Stephan A. Mayer Andy Molyneux Andreas Raabe Peter Vajkoczy Isabel Wanke Aline Frey Angelina Marr Sébastien Roux Neal F. Kassell | 2010 | Neurocritical Care2010，，3： | 1 |
| 7 | Histological evidence of delayed ischemic brain tissue damage in the rat double-hemorrhage model显示文摘 | Erdem Güresir Andreas Raabe Alongkorn Jaiimsin Santosh Dias Peter Raab Volker Seifert Hartmut Vatter | 2010 | Journal of the Neurological Sciences2010，，1： | 1 |
| 8 | Can we trust mass spectrometry for determination of arsenic peptides in plants: comparison of LC–ICP–MS and LC–ES-MS/ICP–MS with XANES/EXAFS in analysis of Thunbergia alata显示文摘 | Katharina Bluemlein Andrea Raab Andrew A. Meharg John M. Charnock J?rg Feldmann | 2008 | Analytical and Bioanalytical Chemistry2008，，7： | 1 |
| 9 | Tumour response and secondary resectability of colorectal liver metastases following neoadjuvant chemotherapy with cetuximab: the CELIM randomised phase 2 trial显示文摘 | Gunnar Folprecht Thomas Gruenberger Wolf O Bechstein Hans-Rudolf Raab Florian Lordick J?rg T Hartmann Hauke Lang Andrea Frilling Jan Stoehlmacher Jürgen Weitz Ralf Konopke Christian Stroszczynski Torsten Liersch Detlev Ockert Thomas Herrmann Eray Goekkurt | 2010 | Lancet Oncology2010，，1： | 1 |
| 10 | SUBARACHNOID HEMORRHAGE AND INTRACEREBRAL HEMATOMA: INCIDENCE, PROGNOSTIC FACTORS, AND OUTCOME显示文摘 | Erdem Güresir Jürgen Beck Hartmut Vatter Matthias Setzer Rüdiger Gerlach Volker Seifert Andreas Raabe | 2008 | Neurosurgery2008，，6： | 1 |
| 11 | 长期储存对钛和氧化锆树脂粘结效果的影响显示文摘目的:探究长期储存对树脂粘结剂在钛和氧化锆之间粘结效果的影响。方法和材料:4级钛块粘结在氧化钛片上,使用以下4种树脂:Panavia F2.0(Kuraray Europe).GCG-Cem(GCEurope),RelyX Unicem(3MESPE),SmartCem2(Dentsply DeguDent)。在37。C水浴分别保存24h、16d、90d、150d和6000次5~55℃冷热循环后检测粘结抗剪切强度。使用扫描电镜评价材料断裂模式。结果:保存90d组以及冷热循环后GCG-Cem抗剪切强度(16.9MPa,151MPa)和RelyX Unicem(10.8MPa.157MPa)比SmartCem2(71MPa,4.OMPa)以及PanaviaF2(4.1MPa,74MPa)粘结抗剪切强度高。保存150d组中,GCG—Cem和RelyX Unicem发生了混合破坏。1/3的SmartCem2和Panavia F2样本发生内聚破坏;其他样本为混合破坏模式。24h组抗剪切强度分别为(GCG-Cem:26.OMPa.RelyX Unicem:205MPa.smartcem2:16.1MPa.PanaviaF2:23.6MPa)和16d组抗剪切强度分别为(GCG-Cem:12.8.RelyX Unicem:142MPa.SmartCem2:98MPa.PanaviaF2:147MPa).4种材料的抗剪切性能是相似的。结论:保存时间和冷热循环对氧化锆和钛的树脂粘结效果有不同程度的影响。 | Barbara Cvikl Mirza Dragic Alexander Franz Modesto Raabe Reinhard Gruber Andreas Moritz 何艺婷 | 2017 | 中国口腔医学继续教育杂志2017，20，2： | 0 |
| 12 | Quantitative chemical proteomics reveals a Plkl inhibitor-compromised cell death pathway in human cells显示文摘 | Monika Raab Fiona Pachl Andrea Kraemer Elisabeth Kurunci-Csacsko Christina Doetsch Rainald Knecht Sven Becker Bernhard Kuster Klaus Strebhardt | 2014 | Cell Research2014，24，9： | 0 |
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