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| 1 | 美国湿地保护制度变迁研究显示文摘本文提出了分析湿地保护制度变迁的理论框架,使不同国家的湿地保护制度研究能在统一语境下比较。首先基于科学计量学和系统研究方法筛选出公众、科学、政府和法律为影响湿地保护制度变迁的四个关键要素,并依赖博弈论工具建立了分析美国湿地保护制度的理论架构。基于这一架构,本文对包括关键利益相关者、政策执行路径、政策工具和管理挑战等内容的美国湿地政策史进行了讨论。对美国湿地保护制度的演化进行了四阶断之划分:'西进运动'与全民开垦(1900年之前)、'水鸟保护'与公众参与(1900-1970年)、核心法律与科学研究(1971-1980年)和完善制度与新的挑战(1980年至今)。分析得出如下结论:在湿地保护制度中,公众是源头、科学是前提、有效的政府管治和将湿地保护的规则和与政策制度化是关键。通过借鉴美国湿地保护制度变迁研究,本文构建了湿地保护制度变迁的'竹节模式'经验性模型,揭示了各动因之间的作用机理。虽然美国湿地保护制度也面临着公众教育、科学定义和政府管辖权等挑战,但中国的湿地管理者与政策制定者仍可从美国湿地政策执行的历史背景中吸取经验。同时本文的理论分析结构也可为自然资源及管理策略的研究提供参考。 | 陈溪 Magdeline Laba Robertson Morgan Barbara Cosens 王子彦 陈雪 James Anderson Marinus Otte Christopher Craft David Feldman 李杨帆 刘晶岚 Patrick Sullivan 吕宪国 | 2016 | 资源科学2016，38，4： | 13 |
| 2 | Chromosome-scale scaffolding of the black raspberry (Rubus occidentalis L.) genome based on chromatin interaction data显示文摘Black raspberry(Rubus occidentalis L.)is a niche fruit crop valued for its flavor and potential health benefits.The improvement of fruit and cane characteristics via molecular breeding technologies has been hindered by the lack of a high-quality reference genome.The recently released draft genome for black raspberry(ORUS 4115-3)lacks assembly of scaffolds to chromosome scale.We used high-throughput chromatin conformation capture(Hi-C)and Proximity-Guided Assembly(PGA)to cluster and order 9650 out of 11,936 contigs of this draft genome assembly into seven pseudo-chromosomes.The seven pseudo-chromosomes cover~97.2%of the total contig length(~223.8 Mb).Locating existing genetic markers on the physical map resolved multiple discrepancies in marker order on the genetic map.Centromeric regions were inferred from recombination frequencies of genetic markers,alignment of 303 bp centromeric sequence with the PGA,and heat map showing the physical contact matrix over the entire genome.We demonstrate a high degree of synteny between each of the seven chromosomes of black raspberry and a high-quality reference genome for strawberry(Fragaria vesca L.)assembled using only PacBio long-read sequences.We conclude that PGA is a cost-effective and rapid method of generating chromosome-scale assemblies from Illumina short-read sequencing data. | Rubina Jibran Helge Dzierzon Nahla Bassil Jill M.Bushakra Patrick P.Edger Shawn Sullivan Chad E.Finn Michael Dossett Kelly J.Vining Robert VanBuren Todd C.Mockler Ivan Liachko Kevin M.Davies Toshi M.Foster David Chagné | 2018 | Horticulture Research2018，5，1： | 4 |
| 3 | Targeting the mitochondrial permeability transition pore in traumatic central nervous system injury显示文摘The mitochondrion serves many functions in the central nervous system(CNS) and other organs beyond the well-recognized role of adenosine triphosphate(ATP) production. This includes calcium-dependent cell signaling, regulation of gene expression, synthesis and release of cytotoxic reactive oxygen species, and the release of cytochrome c and other apoptotic cell death factors. Traumatic injury to the CNS results in a rapid and, in some cases, sustained loss of mitochondrial function. One consequence of compromised mitochondrial function is induction of the mitochondrial permeability transition(mPT) state due to formation of the cyclosporine A sensitive permeability transition pore(mPTP). In this mini-review, we summarize evidence supporting the involvement of the mPTP as a mediator of mitochondrial and cellular demise following CNS traumatic injury and discuss the beneficial effects and limitations of the current experimental strategies targeting the mPTP. | Joe E. Springer Pareshkumar Prajapati Patrick G. Sullivan | 2018 | Neural Regeneration Research2018，13，8： | 3 |
| 4 | 一种房颤风险评分系统的建立(Framingham心脏研究):基于社区的队列研究显示文摘背景房颤导致了发病率和病死率的显著上升。本研究旨在建立一种预测个体罹患房颤绝对风险的风险评分系统,并提供研究人员评价新危险因素的流程。方法作者评估了Framingham心脏研究中于1968年6月至1987年9月间进行了8044次检测的4764例参与者(55%为女性,年龄45~95岁)。此后,参与者被随访至房颤首发,随访期最长达10年。多变量Coxi回归确认出1(1年内罹患房颤的临床危险因素。次级分析纳入了常规超声心动图检测指标(5152例4参与者,7156次检测)对房颤风险进行再分层评估,并评价超声检测指标能否提高风险预测能力。结果4764例参与者中的457例4(10%)罹患房颤。年龄、性别、体重指数、收缩压、降压治疗、PR间期、有临床意义的心脏杂音及心力衰竭与房颤相关,并被纳入了风险评分模型(除体重指数P=0.08外,其余均为P〈0.05),模型的C统计量为0.78(95%CI0.76~0.80)。10年房颤风险随年龄变化:年龄〈65岁的人群中53例(1%)风险高于15%,而〉65岁的人群中为783例(27%)。为提高预测能力而纳入超声检测指标仅使模型C统计量略微增高,由0.78(95%C10.75~0.80)增至0.79(95%CI0.77~0.82:P=0.005)。超声心动图检测指标并不能改善风险再分层评估(P=0.18)。结论基于社区医疗中易得的临床因素建立的风险评分系统,有助于确认社区个体罹患房颤的风险,评估技术或标志物能否改善风险预测,以及针对高危个体采取预防措施。 | Renate B Schnabel Lisa M Sullivan Daniel Levy Michael J Pencina Joseph M Massaro Ralph B D'Agostino Sr Christopher Newton-Cheh Jennifer F Yamamoto Jared W Magnani Thomas M Tadros William B Kannel Thomas J Wang Patrick T Ellinor Philip A Wolf Ramachanclran S Vasan Emelia J Benjamin 黄刚(译) | 2009 | 世界临床医学2009，，9： | 2 |
| 5 | Developing a Model for Management Intellectual Capital显示文摘 | Lief Edvinsson Patrick Sullivan | 1996 | European Management Journal1996，，4： | 1 |
| 6 | A probabilistic method of testing for the assessment of deterioration and explosive spalling of high strength concrete beams in flexure at high temperature 显示文摘 | Patrick J E Sullivan | 2004 | Cement and Concrete Composites2004，26，： | 1 |
| 7 | Profiting from Intellectual Capital: Learning from Leading Companies 显示文摘 | HARRISON SUZANNE SULLIVAN H PATRICK Sr | 2000 | 1 (1): 33-462000，1，1： | 1 |
| 8 | Spillover effects,cost savings,R&D and the use of brand extensions显示文摘 | Patrick DeGraba and Mary W Sullivan | 1995 | International Journal of Industrial Organization1995，13，： | 1 |
| 9 | Develop a Model for Management Intellectual Capital 显示文摘 | LEIF EDVINSSON PATRICK SULLIVAN | 1996 | European Management Journal1996，14，4： | 1 |
| 10 | Developing a Model for Management Intellectual Capital显示文摘 | Leif Edvinsson & Patrick Sullivan | 1996 | European Management JournaI Vol14 No41996，，： | 1 |
| 11 | Developing a model for managing intellectual capital显示文摘 | Patrick Sullivan | 1996 | European Management Journal1996，14，4： | 1 |
| 12 | Developing a Model for Managing Intellectual Capital显示文摘 | Patrick Sullivan | 1996 | European Management Journal1996，，4： | 1 |
| 13 | Sensitivity and spe- cificity of the geriatric anxiety inventory and the hospital anxiety and depression scale in the detection of anxiety disorders in older people with chronic obstructive pulmo- nary disease显示文摘 | Cheung G Patrick C Sullivan G | 2012 | Int Psychogeriatr2012，24，1： | 1 |
| 14 | Developing a model for management intellectual capital 显示文摘 | Leif Edvinsson Patrick Sullivan | 1996 | European Management Journal1996，14，4： | 1 |
| 15 | Reception moments, modem literarytheory ,and the teaching of literature显示文摘 | Sullivan Patrick | 2002 | Journal of ado-lescent & adult literacy2002，，： | 1 |
| 16 | The epidemiology and impact of pancreatic diseases in the United States显示文摘 | Albert B. Lowenfels MD Thomas Sullivan BS John Fiorianti MD Patrick Maisonneuve MS | 2005 | Current Gastroenterology Reports2005，，2： | 1 |
| 17 | Conditions Comorbid with Chronic Fatigue in a Population-Based Sample显示文摘 | Elizabeth J. Dansie Helena Furberg Niloofar Afari Dedra Buchwald Karen Edwards Jack Goldberg Ellen Schur Patrick F. Sullivan | 2012 | Psychosomatics2012，，1： | 1 |
| 18 | Develop a Model for Man agement Intellectual Capital显示文摘 | LeifEdvinsson & Patrick Sullivan | 1996 | European Management Jour na11996，14，4： | 1 |
| 19 | Cardiac Remote Ischemic Preconditioning in Coronary Stenting (CRISP Stent) Study: A Prospective, Randomized Control Trial显示文摘 | Stephen P. Hoole Patrick M. Heck Linda Sharples Sadia N. Khan Rudolf Duehmke Cameron G. Densem Sarah C. Clarke Leonard M. Shapiro Peter M. Schofield Michael O’Sullivan David P. Dutka | 2009 | Circulation2009，，6： | 1 |
| 20 | 面部年轻化治疗中口周小丘的外科治疗及其解剖学基础显示文摘背景与目的面部年轻化治疗的求美者常有口周软组织“早老化”现象,然而,其成因却并不明确。随着面部的衰老,面部各部位皮下脂肪室不同程度地受累。既往有较多关于眶周、中面部和下颌老化及其年轻化治疗的研究。但对于老化导致的口周小丘的研究较少。方法笔者通过尸头解剖研究,探索口周老化的成因。本组8具新鲜尸头,行固定处理,所有标本口周组织完整。对口周区域进行解剖,行解剖学观察及组织学检查其老化性改变。发现其解剖学特点后。笔者根据其相对于正常组织的欠缺,制定年轻化手术方案。结果组织学检查显示,口周小丘实际是一块脂肪瘤样组织.其周围没有明确附着韧带或包膜。这个瘤样组织内的细胞团之间存在菲薄的纤维性隔膜,与周同组织分隔开,这一纤维性隔膜对其起到结构性支撑作用。尸头解剖显示,其为浅层脂肪的异常堆积。这一口周组织肥厚、下垂的症状.通过传统除皱术很难得到解决。结论口周小丘可能是一个小的、独立的脂肪室或由鼻唇脂肪室延伸而来。本研究增加了对口周区域深人的理解,有助于促进口周年轻化治疗方法的改进。笔者的首选方法是通过细管行脂肪抽吸的脂肪雕塑。 | Patrick K. Sullivan Erik A. Hoy Vineet Mehan David P. Singer 魏峰(译) 高景恒(译) 张晨(译) | 2011 | 中国美容整形外科杂志2011，22，1： | 1 |
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