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| 1 | 澳大利亚精神卫生主流服务模式介绍显示文摘墨尔本大学ST Vincent's精神卫生部承担着西太平洋地区国家的精神卫生服务人员的培训,中国也曾多次派出专业人员接受过社区精神卫生服务的训练。由于培训时间的限制,有些学员对一些问题尚有不清楚之处,因此,本文试图对澳大利亚维多利亚州的主流精神卫生服务模式做一介绍,以其惠及国内更多的精神卫生服务人员。 | 刘铁桥 马弘 Chee Ng | 2007 | 国际精神病学杂志2007，34，1： | 20 |
| 2 | Gastric peritoneal carcinomatosis-a retrospective review显示文摘AIM To characterize patients with gastric peritoneal carcinomatosis(PC) and their typical clinical and treatment course with palliative systemic chemotherapy as the current standard of care.METHODS We performed a retrospective electronic chart review of all patients with gastric adenocarcinoma with PC diagnosed at initial metastatic presentation between January 2010 and December 2014 in a single tertiary referral centre.RESULTS We studied a total of 271 patients with a median age of 63.8 years and median follow-up duration of 5.1 mo. The majority(n = 217, 80.1%) had the peritoneum as the only site of metastasis at initial presentation. Palliative systemic chemotherapy was eventually planned for 175(64.6%) of our patients at initial presentation, of which 171 were initiated on it. Choice of first-line regime was in accordance with the National Comprehensive Cancer Network Guidelines for Gastric Cancer Treatment. Thesepatients underwent a median of one line of chemotherapy, completing a median of six cycles in total. Chemotherapy disruption due to unplanned hospitalizations occurred in 114(66.7%), while cessation of chemotherapy occurred in 157(91.8%), with 42 cessations primarily attributable to PC-related complications. Patients who had initiation of systemic chemotherapy had a significantly better median overall survival than those who did not(10.9 mo vs 1.6 mo, P < 0.001). Of patients who had initiation of systemic chemotherapy, those who experienced any disruptions to chemotherapy due to unplanned hospitalizations had a significantly worse median overall survival compared to those who did not(8.7 mo vs 14.6 mo, P < 0.001).CONCLUSION Gastric PC carries a grim prognosis with a clinical course fraught with disease-related complications which may attenuate any survival benefit which palliative systemic chemotherapy may have to offer. As such, investigational use of regional therapies is warranted and required validation in patients with isolated PC to maximize their survival outcomes in the long run. | Hwee Leong Tan Claramae Shulyn Chia Grace Hwei Ching Tan Su Pin Choo David Wai-Meng Tai Clarinda Wei Ling Chua Matthew Chau Hsien Ng Khee Chee Soo Melissa Ching Ching Teo | 2017 | World Journal of Gastrointestinal Oncology2017，9，3： | 6 |
| 3 | Adjunctive aripiprazole for antipsychotic-related hyperprolactinaemia in patients with first-episode schizophrenia:a metaanalysis显示文摘Background Hyperprolactinaemia is a common antipsychotic(AP)-induced adverse effect,particularly in female patients.Aims This meta-analysis examined the efficacy and safety of adjunctive aripiprazole in preventing AP-related hyperprolactinaemia in patients with first-episode schizophrenia.Methods PubMed,PsycINFO,EMBASE,Cochrane Library,WanFang and China Journal Net databases were searched to identify eligible randomised controlled trials(RCTs).Primary outcomes were the reductions of serum prolactin level and prolactin-related symptoms.Data were independently extracted by two reviewers and analysed using RevMan(V.5.3).Weighted/standardised mean differences(WMDs/SMDs)±95%Cis were reported.Results In the five RCTs(n=400),the adjunctive aripiprazole(n=197)and the control groups(n=203)with a mean of 11.2 weeks of treatment duration were compared.The aripiprazole group had a significantly lower endpoint serum prolactin level in all patients(five RCTs,n=385;WMD:-50.43 ng/mL(95%Cl:-75.05 to-25.81),p<0.00001;l2=99%),female patients(two RCTs,n=186;WMD:-22.58 ng/mL(95%Cl:-25.67 to-19.49),p<0.00001;l2=0%)and male patients(two RCTs,n=127;WMD:-68.80 ng/mL(95%Cl:-100.11 to-37.49),p<0.0001).In the sensitivity analysis for the endpoint serum prolactin level in all patients,the findings remained significant(p<0.00001;l2=96%).The aripiprazole group was s叩erior to the control group in improving negative symptoms as assessed by the Positive and Negative Syndrome Scale(three RCTs,n=213;SMD:-0.51(95%Cl:-0.79 to-0.24),p=0.0002;l2=0%).Adverse effects and discontinuation rates were similar between the two groups.Conclusions Adjunctive aripiprazole appears to be associated with reduced AP-induced hyperprolactinaemia and improved prolactin-related symptoms in first-episode schizophrenia.Further studies with large sample sizes are needed to confirm these findings. | Wei Zheng Dong-Bin Cai Xin-Hu Yang Wei Zheng Gabor S Ungvari Chee H Ng Zhan-Ming Shi Mei-Ling Hu Yu-Ping Ning Yu-Tao Xiang | 2019 | General Psychiatry2019，32，5： | 4 |
| 4 | Comparing models of mental health service systems between Australia and China: implications for the future development of Chinese mental health service显示文摘 | LIU Tie-qiao Ng Chee MA Hong David Castle HAO Wei LI Ling-jiang and | 2008 | Chinese Medical Journal2008，，14： | 3 |
| 5 | Adjunctive Peony-Glycyrrhiza decoction for antipsychotic-induced hyperprolactinaemia:a meta-analysis of randomised controlled trials显示文摘Background Hyperprolactinaemia is a common adverse effect of antipsychotics(APs). The results of PeonyGlycyrrhiza decoction(PGD) as a potentially useful adjunctive treatment for hyperprolactinaemia are inconsistent.Aim This meta-analysis of randomised controlled trials(RCTs) examined the efficacy and safety of adjunctive PGD therapy for AP-induced hyperprolactinaemia.Methods English(PubMed, Embase, Cochrane Library,PsycINFO) and Chinese(Chinese National Knowledge Infrastructure, Wanfang Data) databases were systematically searched up to 10 June 2018. The inclusion criteria were based on PIC0 S一/^rticipants: adult patients with schizophrenia; Aitervention: PGD plus APs; Cbmparison: APs plus placebo or AP monotherapy;(Xjtcomes: efficacy and safety; Study design: RCTs. The weighted mean difference(WMD) and risk ratio(RR) along with their 95% CIs were calculated using Review Manager(RevMan) V.5.3 software.Results Five RCTs(n=450) were included and analysed.Two RCTs(n=140) were double-blind and four RCTs(n=409) reported ‘random' assignment with specific description. The PGD group showed a significantly lower serum prolactin level at endpoint than the control group(n=380, WMD:-32.69 ng/mL(95% Cl-41.66 to 23.72),/X0.00001, ^=97%). Similarly, the superiority of PGD over the control groups was also found in the improvement of hyperprolactinaemia-related symptoms. No difference was found in the improvement of psychiatric symptoms assessed by the Positive and Negative Syndrome Scale(n=403,WMD:-0.62(95% Cl-2.38 to 1.15), p=0.49, ^=0%). There were similar rates of all-cause discontinuation(n=330, RR0.93(95% Ci 0.63 to 1.37),/t=0.71, ^=0%) and adverse drug reactions between the two groups. According to the Grading of Recommendations Assessment, Development and Evaluation approach, the level of evidence of primary and secondary outcomes ranged from ‘very low'(14.3%),‘low'(42.8%),‘moderate'(14.3%),to ‘high,(28.6%>.Conclusions Current evidence supports the adjunctive use of PGD to suppress elevated prolactin and improve prolactininduced symptoms without significant adverse events in adult patients with AP-induced hyperprolactinaemia. Highquality RCTs with longer duration are needed to confirm these findings.Trial registration number 42016037017. | Wei Zheng Dong-Bin Cai Hai-Yan Li Yu-Jie Wu Chee H Ng Gabor S Ungvari Shan-Shan Xie Zhan-Ming Shi Xiao-Min Zhu Yu-Ping Ning Yu-Tao Xiang | 2018 | General Psychiatry2018，31，4： | 3 |
| 6 | Antipsychotic Medications in Major Depression and the Association with Treatment Satisfaction and Quality of Life: Findings of Three National Surveys on Use of Psychotropics in China Between 2002 and 2012显示文摘 | Yu-Xi Wang Yu-Tao Xiang Yun-Ai Su Qian Li Liang Shu Chee H Ng Gabor S Ungvari Helen FK Chiu Yu-Ping Nin Gao-Hua Wang Pei-Shen Bai Tao Li Li-Zhong Sun Jian-Guo Shi Xian-Sheng Chen Qi-Yi Mei Ke-Qing Li Xin Yu Tian-Mei Si | 2015 | Chinese Medical Journal2015，，14： | 2 |
| 7 | Comparing the stigma of mental illness in a general hospital with a state mental hospital显示文摘 | Chee CYI Ng TP Kua EH | 2005 | Social Psychiatry and Psychiatric Epidemiology2005，40，： | 1 |
| 8 | Efficacy and cognitive effects of right unilateral electroconvulsive therapy 显示文摘 | Chee Ng Isaac Schweitzer MD | 2007 | The Journal of ECT2007，16，4： | 1 |
| 9 | Lower circulating irisin is associated with type 2 diabetes mellitus显示文摘 | Jian-Jun Liu Melvin D.S. Wong Wan Ching Toy Clara S.H. Tan Sylvia Liu Xiao Wei Ng Subramaniam Tavintharan Chee Fang Sum Su Chi Lim | 2013 | Journal of Diabetes and Its Complications2013，，4： | 1 |
| 10 | Application of higher order spectra for the identifcation of diabetes retinopathy stages显示文摘 | Acharya UR Chua KC Ng EYK Wei W Chee C | 2008 | Journal of Medical Systems2008，32，6： | 1 |
| 11 | Tendon stress and flexural strength of externally prestressed beams 显示文摘 | NG CHEE - KHOON | 2003 | ACI Structural Journal2003，100，5： | 1 |
| 12 | Comparing the stigma of mental illness ina general hospital with a state mental hospital:a Singapore study 显示文摘 | Chee CY Ng TP Kua EH | 2005 | Soc Psychiatry Psychiatr Epidemio12005，40，8： | 1 |
| 13 | SJWD14072900000111显示文摘 | Jin Yao Teo Brian Kim Poh Goh Foong Koon Cheah John Carson Allen Richard Hoau Gong Lo David Chee Eng Ng Anthony Soon Whatt Goh Andrew Yu Keat Khor Hui Shan Sim Jia Jun Ng Pierce Kah‐Hoe Chow | 2014 | Journal of Digestive Diseases2014，，8： | 1 |
| 14 | Comparing the stigma of mental illness ina general hospital with a state mental hospital : a Singapore study 显示文摘 | Chee CY Ng TP Kua EH | 2005 | Soc Psychiatry Psychiatr Epidemio12005，40，8： | 1 |
| 15 | Disturbance decoupled fault reconstruction using cascaded sliding mode observers 显示文摘 | Kok Yew Ng Chee Pin Tan Denny Oetomo | 2012 | Automatica2012，48，5： | 1 |
| 16 | Efficacy and Cognitive Effects of Right Unilateral Electroconvulsive Therapy显示文摘 | Chee Ng Isaac Schweitzer | 2007 | The Journal of ECT2007，16，4： | 1 |
| 17 | Comparing the stigma ofmental illness in a general hospital with a state mental hospital:a Singapore Study显示文摘 | Chee CYI Ng TP Kua EH | 2005 | Social Psychiatry and Psychiatric Epidemiology2005，40，8： | 1 |
| 18 | Comparing the stigma of mental ill- ness in a general hospital with hospital 显示文摘 | Chee C Y I Ng T P Kua E H | 2005 | Social Psychiatry and Psychiatric Epidemiology2005，40，8： | 1 |
| 19 | Heavy metal contents in soil of major towns in the east coast of Peninsular Malaysia显示文摘 | Seng Chee Poh Norhaxati Mohd Tahir Hafiza Mohamed Zuki Mohd Izwadi Musa Khai Hock Ng Noor Azhar Mohamed Shazili | 2006 | Chinese Journal Of Geochemistry2006，25，B08： | 1 |
| 20 | Deciphering the Sox-Oct partner code by quantitative cooperativity measurements显示文摘 | Calista K. L. Ng Noel X. Li Sheena Chee Shyam Prabhakar Prasanna R. Kolatkar Ralf Jauch | 2012 | Nucleic Acids Research2012，，11： | 1 |
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