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| 1 | Association of psychological risk factors and acute myocardial infarction in China: the INTER-HEART China study显示文摘背景关于关于尖锐心肌的梗塞(AMI ) 的心理因素的大多数数据从在西方的国家执行的研究被获得。从在中国的小描述的代表性的研究的结果是不确定的。这研究的目的是与这研究是的大规模盒子控制 study.Methods 在中国人口之中探索在心理风险因素和 AMI 之间的可能的协会内部心的中国学习的部分,心血管的风险因素的大国际内部心的学习的自己部分。在这盒子控制研究, 2909 个盒子和 2947 控制从 17 cities.Psychological 应力被招募,否定生活事件,生活情形的消沉和可控制性是案例报导了的 assessed.Results 在家或工作和机会比率( ORs )的更心理的应力是 3.2 (95% CI 2.1-4.9 )为永久应力并且 2.1 (95% CI 1.5-2.8 )为应力的几个时期分别地。更多的案例与控制(19.6% 对 9.3%) 相比经历了消沉, ORs 是 2.2 (95% CI 1.9-2.6 ) 。分别地,有 1, 2 和 3 的题目或更压抑的症状由 2.1, 2.2 和 2.6 褶层增加了 AMI 的风险即,更压抑的症状与 AMI (为趋势 0.0001 的 P ) 的更高的风险被联系。女人们从消沉有 AMI 的更大的风险(或 3.0, 95% CI 2.2-4.0 ) 与男人相比(或 2.0, 95% CI 1.6-2.4 ) ,为相互作用 =0.0364 的 P。在题目的否定生活事件与 AMI 的增加的风险被联系,或 1.7 (95% CI 1.4-2.0 ) 为一个事件并且 1.8 (95% CI 1.3-2.4 ) 为二或更多的事件。生活情形的可控制性的高水平为 AMI 减少了风险(或 0.8, 95%CI 0.7-1 .0 ).Conclusions 几个心理因素仔细在中国 population.Psychological 应力之中与增加的 AMI 风险被联系在男人有更大的 AMI 风险,但是消沉在女人之中是更重要的。 | XU Tao LI Wei Koon Teo WANG Xing-yu LIU Li-sheng Salim Yusuf | 2011 | Chinese Medical Journal2011，，14： | 29 |
| 2 | 尿钠排泄、血压、心血管病与死亡率的关系:社区前瞻性流行病学队列研究显示文摘WHO建议人群钠摄人<2 g/d作为预防心血管病的措施之一,但这一目标在任何国家都没有实现。该建议主要基于短期血压试验的个体水平数据,没有来自随机试验或观察性研究的关于低钠摄入与降低心血管事件的数据。前瞻性城市农村流行病学研究目前正在21个国家进行。该文对其中18个国家的数据进行分析,其中包含了临床结果数据。 | Mente A O'Donnell M Rangarajan S McQueen M Dagenais G Wielgosz A Lear S Ah STL Wei L Diaz R Avezum A Lopez-Jaramillo P Lanas F Mony P Szuba A Iqbal R Yusuf R Mohammadifard N Khatib R Yusoff K Ismail N Gulec S Rosengren A Yusufali A Kruger L Tsolekile LP Chifamba J Dans A Alhabib KF Yeates K Teo K Yusuf S 刘莉 叶鹏 | 2018 | 中华高血压杂志2018，26，12： | 29 |
| 3 | Epinephrine injection therapy versus a combination of epinepnrine injection and endoscopic hemoclip in the treatment of bleeding ulcers显示文摘AIM: To assess the efficacy of hemoclip application in combination with epinephrine injection in the treatment of bleeding peptic ulcers and to compare the clinical outcomes between patients treated with such a combination therapy and those treated with epinephrine injection alone.METHODS: A total of 293 patients (211 males, 82females) underwent endoscopic therapy for bleeding peptic ulcers. Of these, 202 patients (152 males, 50females) received epinephrine injection therapy while 91patients (59 males, 32 females) received combination therapy. The choice of endoscopic therapy was made by the endoscopist. Hemostatic rates, rebleeding rates, need for emergency surgery and 30-d mortality were the outcome measures studied.RESULTS: Patients who received combination therapy were significantly older (mean age 66±16 years, range24-90 years) and more suffered from chronic renal failure compared to those who received epinephrine injection therapy alone (mean age 61±17 years, range 21-89 years).Failure to achieve permanent hemostasis was 4% in the group who received epinephrine injection alone and 11%in the group who received combination therapy. When the differences in age and renal function between the two treatment groups were taken into account by multivariate analysis, the rates of initial hemostasis,rebleeding rates, need for surgery and 30-d mortality for both treatment options were not significantly different.CONCLUSION: Combination therapy of epinephrine injection with endoscopic hemoclip application is an effective method of achieving hemostasis in bleeding peptic ulcer diseases. However, superiority of combination therapy over epinephrine injection alone, could not be demonstrated. | Tju-Siang Chua Kwong-Ming Fock Tay-Meng Ng Eng-Kiong Teo Jessica Yi-Lyn Tan Tiing-Leong Ang | 2005 | World Journal of Gastroenterology2005，11，7： | 27 |
| 4 | An update on transurethral surgery for benign prostatic obstruction显示文摘Clinical benign prostatic hyperplasia(BPH)is one of the most common cause of lower urinary tract symptoms and transurethral resection of prostate(TURP)has been the gold standard technique for surgical treatment of benign prostate obstruction(BPO)over the last 2 decades.Although monopolar TURP is considered a safe and effective option for surgical management of BPO,there are some disadvantages,namely bleeding,transurethral resection syndrome,incompleteness of treatment.This review aims to highlight these problems,and describe the advances in technology and techniques that have evolved to minimise such complications.With the advent of lasers and bipolar technology,as well as enucleative techniques to remove the prostatic adenoma/adenomata,the problems of bleeding,transurethral resection syndrome and incomplete treatment are significantly minimised.Monopolar TURPwill likely be replaced by such technology and techniques in the near future such that transurethral surgery of the prostate remain a safe and effective option in alleviating the harmful effects of BPO. | Jonathan Shunming Teo Yee Mun Lee Henry Sun Sien Ho | 2017 | Asian Journal of Urology2017，4，3： | 20 |
| 5 | 高危患者目标血压与心血管病预后显示文摘指南推荐血压目标值应〈140/90 mmHg(1mmHg=0.133kPa)以减少心血管事件的发生。但与其他心血管病预后(如冠状动脉事件)相比,包括脑卒中及心力衰竭在内的心血管病预后与收缩压下降关系更密切。一些心血管事件(如冠状动脉事件)风险在收缩压低时亦增高,风险-收缩压关系呈J形曲线,而脑卒中与血压不是J形曲线关系。 | B?hm M Schumacher H Teo KK Lonn EM Mahfoud F Mann JF Mancia G Redon J Schmieder RE Sliwa K Weber MA Williams BYusuf S 曲浥晨 叶鹏 | 2017 | 中华高血压杂志2017，25，6： | 14 |
| 6 | 测试英语词汇的广度、深度和强度显示文摘自98年Laufer两次进行广度结合强度的三层面英语词汇知识研究后,Laufer et al于2004年两次进行了四层面词汇知识研究,首次提出并正在进行词汇广度结合强度的计算机机测的研究工作。在词汇研究领域原有的广度和深度上,又开辟了一条新的道路。文章试讨论80年代以来国内外就测试英语词汇的广度、深度和强度的主要研究,尝试探讨这些研究对我们英语词汇测试研究与词汇学习的启示。 | 钟志英 Adisa Teo Chonlada Laohawiriyanon | 2005 | 华南农业大学学报(社会科学版)2005，4，4： | 12 |
| 7 | A comparison of the clinical, demographic and psychiatric profiles among patients with erosive and non-erosive reflux disease in a multi-ethnic Asian country显示文摘AIM: To examine the clinical spectrum of gastroesophageal reflux disease (GERD) and compare erosive (ERD) with non-erosive (NERD) in terms of clinical, demographic and psychiatric profiles.METHODS: Patients with reflux symptoms were enrolled and stratified to NERD and ERD after endoscopy (LA classification). Patients with ERD presenting with dyspepsia were included. Patients on proton pump inhibitors (PPI) or H2 receptor antagonists before endoscopy were excluded.Demographic data, Helicobacter pylori (H pylon) status and presence of minor psychiatric morbidity (based on General Health Questionnaire-28) were analyzed. RESULTS: Among 690 patients screened, 533 were eligible for analysis (male to female ratio: 3:2; Chinese: 75.4%; Malay: 9.8%; Indian: 14.8%). Clinical spectrum of GERD: N: 40.5%; A: 46%; B: 9.2%; C: 2.1%; D: 0.6%; Barrett's esophagus: 1.7%. Compared to patients with NERD, patients with ERD were significantly older (45 vs 39.4 years), more likely to be male (64.4% vs 53.7%),tended to smoke (19.6% vs 9.7%), less likely to haveminor psychiatric morbidity (26.4 vs 46.7%) and were more likely to respond to PPI (79.7 vs66.8%). There wasalso a trend towards a higher BMI (24.5 vs 23.5). Race,alcohol consumption and H pylori status were not significant.On multivariate analysis, age and presence of minor psychiatric morbidity remained with significant differences. CONCLUSION: The majority of patients who have typical symptoms of GERD have NERD or mild erosive reflux disease. Compared to patients with erosive reflux disease, patients with NERD were younger and had a higher prevalence of minor psychiatric morbidity. | Tiing-Leong Ang Kwong-Ming Fock Tay-Meng Ng Eng-Kiong Teo Tju-Siang Chua Jessica Tan | 2005 | World Journal of Gastroenterology2005，11，23： | 12 |
| 8 | 中日学校体育场馆设施开放利用分析及启示显示文摘采用文献资料法、比较分析法、数据整理等研究方法,对中日两个学校体育场馆建设政策及开放利用进行梳理分析。认为,日本学校体育场馆设施开放政策执行较早,两国政府建设政策持续推进;日本人均体育场地面积多于我国,占主要体育场地的均为学校体育场馆设施,但日本学校体育场馆设施开放率达98.3%,明显高于我国;主要面向社会大众开放的体育场馆为室外运动场、体育馆、游泳池和网球场;深入社区的小学体育场馆设施开放率最高。政策优惠措施、体育场馆建设资金、委托管理或指定管理者制度、人员培养机制以及安全保障给予日本学校面向社会开放的良好环境,补给社区场馆使用不足。 | 林建君 Teo Ee-Chon | 2015 | 宁波大学学报(人文科学版)2015，28，3： | 11 |
| 9 | 心脏再同步治疗对心肌复极的影响及其潜在致心律失常作用显示文摘目的以双心室起搏为核心技术的心脏再同步治疗技术(CRT)用于治疗慢性心力衰竭(CHF)时可能引起心肌复极异常而具有潜在的致心律失常危险性。本研究以接受CRT的CHF患者为对象,观察反映心肌复极特性的心电图指标在不同部位起搏时的变化及差异,并结合患者转归探讨其意义。方法21例接受CRT和/或CRT-D治疗的CHF患者入选。在植入术过程中或者复查时,将CRT装置分别程控为右心室心内膜起搏(RV-Endo)、左心室心外膜起搏(LV-Epi)和双心室起搏(Biv),同步记录12导联心电图,测量心电图上反映复极时间和复极差异的指标QT间期、JT间期和Tp-e间期,并在不同起搏部位间比较这些参数的差异。结果准确反映心肌复极时间的JT间期和公认代表心肌跨室壁复极离散的Tp-e间期均在LV-Epi起搏时最长[(341.78±61.69)ms,(199.70±62.44)ms],Biv起搏时次之[(325.86±59.19)ms,(184.89±74.08)ms],RV-Endo起搏时最短[(286.14±38.68)ms,(146.41±31.16)ms],三者比较差异有统计学意义(P<0.0001)。QT间期的变化有类似趋势但差异无统计学意义。在(29.18±18.38)个月的随访期中,共发生4例死亡,其中1例猝死,1例发生“心律失常风暴”并最终死于无休止性室性心动过速。结论在CHF患者已有器质性心肌病变的基础上,左心室心外膜起搏和目前CRT采用的双心室起搏延长心肌复极时间并增大跨室壁心肌复极离散,从而为促进恶性心律失常的发生提供了“基质”。 | 吕家高 林立 白融 Wee Siong Teo Ruth Kam 王琳 | 2006 | 中华心律失常学杂志2006，10，2： | 10 |
| 10 | Rabeprazole vs esomeprazole in non-erosive gastro-esophageal reflux disease: A randomized, double-blind study in urban Asia显示文摘AIM:Gastro-esophageal reflux disease (GERD) is becoming increasingly common in Asia. Data on the efficacy of proton pump inhibitors in patients with non-erosive GERD (NERD)in Asia is lacking. This double-blind study compared the efficacy and safety of rabeprazole with esomeprazole in relief of symptoms in patients with NERD.METHODS: One hundred and thirty-four patients with reflux symptoms of NERD and normal endoscopy were randomized to receive rabeprazole 10 mg or esomeprazole 20 mg once daily for 4 wk. Symptoms were recorded in a diary and changes in severity of symptoms noted.RESULTS: At 4 wk of treatment, rabeprazole 10 mg and esomeprazole 20 mg were comparable with regards to the primary endpoint of time to achieve 24-h symptomfree interval for heartburn 8.5 d vs9 d and regurgitation 6 d vs 7.5 d. Rabeprazole and esomeprazole were also similarly efficacious in term of patient's global evaluation with 96% of patients on rabeprazole and 87.9% of patients on esomeprazole, reporting that symptoms improved(P=NS). Satisfactory relief of day- and night-time symptoms was achieved in 98% of patients receiving rabeprazole and 81.4% of patients receiving esomeprazole. Adverse events were comparable in both groups (P = NS).CONCLUSION: Rabeprazole 10 mg has a similar efficacy and safety profile in Asians with NERD as esomeprazole 20 mg. Further study is necessary to investigate whether the small differences between the two drugs seen in this study are related to the improved pharmacodynamicpro perties of rabeprazole. Both drugs were well tolerated. | KM Fock EK Teo TL Ang TS Chua TM Ng YL Tan | 2005 | World Journal of Gastroenterology2005，11，20： | 8 |
| 11 | Helicobacter pylori acquisition of metronidazole resistance by natural transformation in vitro显示文摘INTRODUCTIONGenetictransformationisaprocesbywhichaceltakesupnakedDNAfromthesurroundingmediumandincorporatesitintoitsowngenomi... | HUA Jiesong 1, ZHENG Peng Yuan 1, Teo Keng Fong 1, Khin Mar Mar 2 and HO Bow 1 | 1998 | World Journal of Gastroenterology1998，4，5： | 8 |
| 12 | Levels of CMV-reactive antibodies correlate with the induction of CD28^null T cells and systemic inflammation in chronic obstructive pulmonary disease (COPD)显示文摘 | Dino BA Tan Fathiah S Amran Teck-Hui Teo Patricia Price Yuben P Moodley | 2016 | Cellular & Molecular Immunology2016，13，4： | 8 |
| 13 | 远端血栓保护装置在经皮冠状动脉介入治疗中的应用显示文摘 | 李浪 Tan HuayCheem Teo SweeGuan Lim YeanTeng | 2004 | 中华心血管病杂志2004，32，1： | 7 |
| 14 | Gastric peritoneal carcinomatosis-a retrospective review显示文摘AIM To characterize patients with gastric peritoneal carcinomatosis(PC) and their typical clinical and treatment course with palliative systemic chemotherapy as the current standard of care.METHODS We performed a retrospective electronic chart review of all patients with gastric adenocarcinoma with PC diagnosed at initial metastatic presentation between January 2010 and December 2014 in a single tertiary referral centre.RESULTS We studied a total of 271 patients with a median age of 63.8 years and median follow-up duration of 5.1 mo. The majority(n = 217, 80.1%) had the peritoneum as the only site of metastasis at initial presentation. Palliative systemic chemotherapy was eventually planned for 175(64.6%) of our patients at initial presentation, of which 171 were initiated on it. Choice of first-line regime was in accordance with the National Comprehensive Cancer Network Guidelines for Gastric Cancer Treatment. Thesepatients underwent a median of one line of chemotherapy, completing a median of six cycles in total. Chemotherapy disruption due to unplanned hospitalizations occurred in 114(66.7%), while cessation of chemotherapy occurred in 157(91.8%), with 42 cessations primarily attributable to PC-related complications. Patients who had initiation of systemic chemotherapy had a significantly better median overall survival than those who did not(10.9 mo vs 1.6 mo, P < 0.001). Of patients who had initiation of systemic chemotherapy, those who experienced any disruptions to chemotherapy due to unplanned hospitalizations had a significantly worse median overall survival compared to those who did not(8.7 mo vs 14.6 mo, P < 0.001).CONCLUSION Gastric PC carries a grim prognosis with a clinical course fraught with disease-related complications which may attenuate any survival benefit which palliative systemic chemotherapy may have to offer. As such, investigational use of regional therapies is warranted and required validation in patients with isolated PC to maximize their survival outcomes in the long run. | Hwee Leong Tan Claramae Shulyn Chia Grace Hwei Ching Tan Su Pin Choo David Wai-Meng Tai Clarinda Wei Ling Chua Matthew Chau Hsien Ng Khee Chee Soo Melissa Ching Ching Teo | 2017 | World Journal of Gastrointestinal Oncology2017，9，3： | 6 |
| 15 | Clinical utility,safety and tolerability of capsule endoscopy in urban Southeast Asian population显示文摘AIM:Capsule endoscopy has demonstrated its clinical utility in the evaluation of small bowel pathology in several Western studies. In this prospective study, we aimed to determine the clinical utility, safety and tolerability of capsule endoscopy in the evaluation of suspected small bowel disease in an urban Southeast Asian population.METHODS: We used the given (M2A) capsule endoscopy system in 16 consecutive patients with suspected small bowel pathology. In 9 patients the indication was obscure gastrointestinal bleeding, while in 6 patients it was to determine the extent of small bowel involvement in Crohn's disease. One patient underwent capsule endoscopy for evaluation of chronic abdominal pain. Patient's tolerability to the procedure was evaluated by standardized questionnaires and all patients were reviewed at one week to ensure that the capsule had been excreted without any adverse events.RESULTS: Abnormal findings were present in 8 patients (50%). The cause of obscure gastrointestinal bleeding was determined in 5 out of 9 patients. Findings included 2 cases of angiodysplasia, 2 cases of jejunal ulcers and 1 case of both angiodysplasia and jejunal ulcer. One patient had small bowel erosions and foci of erythema of doubtful significance.Ileal lesions were diagnosed in 2 out of 6 patients with Crohn's disease. Capsule endoscopy was well tolerated by all patients. One patient with Crohn's disease had a complication of capsule retention due to terminal ileum stricture. The capsule eventually passed out spontaneously after 1 month.CONCLUSION: Our study, which represented the first Asian series, further confirms the diagnostic utility, safety and tolerability of wireless capsule endoscopy. | Tiing-Leong Ang Kwong-Ming Fock Tay-Meng Ng Eng-Kiong Teo Yi-Lyn Tan | 2003 | World Journal of Gastroenterology2003，9，10： | 6 |
| 16 | Optical coherence tomography angiography in diabetic retinopathy: a review of current applications显示文摘Background:Diabetic retinopathy(DR)is a leading cause of vision loss in adults.Currently,the standard imaging technique to monitor and prognosticate DR and diabetic maculopathy is dye-based angiography.With the introduction of optical coherence tomography angiography(OCTA),it may serve as a potential rapid,non-invasive imaging modality as an adjunct.Main text:Recent studies on the role of OCTA in DR include the use of vascular parameters e.g.,vessel density,intercapillary spacing,vessel diameter index,length of vessels based on skeletonised OCTA,the total length of vessels,vascular architecture and area of the foveal avascular zone.These quantitative measures may be able to detect changes with the severity and progress of DR for clinical research.OCTA may also serve as a non-invasive imaging method to detect diabetic macula ischemia,which may help predict visual prognosis.However,there are many limitations of OCTA in DR,such as difficulty in segmentation between superficial and deep capillary plexus;and its use in diabetic macula edema where the presence of cystic spaces may affect image results.Future applications of OCTA in the anterior segment include detection of anterior segment ischemia and iris neovascularisation associated with proliferative DR and risk of neovascular glaucoma.Conclusion:OCTA may potentially serve as a useful non-invasive imaging tool in the diagnosis and monitoring of diabetic retinopathy and maculopathy in the future.Future studies may demonstrate how quantitative OCTA measures may have a role in detecting early retinal changes in patients with diabetes. | Kai Yuan Tey Kelvin Teo Anna C.S.Tan Kavya Devarajan Bingyao Tan Jacqueline Tan Leopold Schmetterer Marcus Ang | 2019 | Eye and Vision2019，6，1： | 6 |
| 17 | Monoamine oxidase-B (MAO-B) inhibitors: implications for disease-modification in Parkinson’s disease显示文摘There is a substantial amount of evidence from experimental parkinsonian models to show the neuroprotective effects of monoamine oxidase-B(MAOB)inhibitors.They have been studied for their potential disease-modifying effects in Parkinson’s disease(PD)for over 20 years in various clinical trials.This review provides a summary of the clinical trials and discusses the implications of their results in the context of disease-modification in PD.Earlier clinical trials on selegiline were confounded by symptomatic effects of this drug.Later clinical trials on rasagiline using delayed-start design provide newer insights in disease-modification in PD but success in achieving the aims of this strategy remain elusive due to obstacles,some of which may be insurmountable. | Kay Cheong Teo Shu-Leong Ho | 2013 | Translational Neurodegeneration2013，2，1： | 6 |
| 18 | Palliative surgery for Krukenberg tumors—12-year experience and review of the literature显示文摘AIM To determine the clinical characteristics of patients undergoing palliative surgery for Krukenberg tumors,including disease presentation,outcomes,and prognostic factors.METHODS This was a retrospective clinical study of all patients who underwent palliative surgery for Krukenberg tumors between January 2004 and December 2015.Patient information was obtained from inpatient and outpatient case notes as well as the hospital electronic records.Patients who underwent potential y curative resection,and patients with Krukenberg tumors who did not undergo surgery were also excluded from the study.Palliative surgery was defined as those performed for either alleviation of symptoms or for asymptomatic patients for whom surgical removal of the tumors were deemed necessary following a multidisciplinary consensus.Tumors were diagnosed pre-operatively by computed tomography scans and all had histologic confirmation of the surgical specimens.RESULTS Over the study duration,38 female patients underwent palliative surgery for Krukenberg tumors at our institution.Mean age was 54.2±11.7 years.The colon was the most frequent primary source of metastases(n=21)followed by the stomach(n=4).Prophylactic palliative surgery was performed for eight(21.1%)asymptomatic patients.Median post-operative length of stay was 8 d(IQR 6-12 d).Five patients(13.2%)experienced postoperative complications,although high grade morbidity was only seen in one patient(2.6%).Median overall survival from surgery was 17 mo(95%CI:12.1-21.9)at a median follow-up duration of 12 mo(IQR 8-17mo).The median survival was shorter for patients who underwent emergency surgery,younger patients,those with a colorectal primary,larger tumors,or synchronous peritoneal or hepatic metastases.CONCLUSION Pal iative surgery for Krukenberg tumors can be performed safely with acceptable complication rates.Bilateral oophorectomy should be performed to prevent the risk of symptomatic contralateral tumors. | Isaac Seow-En Gwen Hwarng Grace Hwei Ching Tan Leonard Ming Li Ho Melissa Ching Ching Teo | 2018 | World Journal of Clinical Oncology2018，9，1： | 5 |
| 19 | Telmisartan, ramipril, or both in high-risk Chinese patients: analysis of ONTARGET China data显示文摘背景从进行中的 Telmisartan 的结果独自并且在有 Ramipril 全球端点试用( ONTARGET )的联合显示血管收缩素受体 blocker telmisartan 不低于在在高风险的病人为充血的心失败减少心血管的死亡,心肌的梗塞,击或住院的合成端点的 angiotensin-converting-enzyme 禁止者 ramipril ,并且 telmisartan 与稍微优异的 tolerability 被联系。没有利益的增加,二药的联合与更不利的事件被联系。这研究试图从从在中国注册的病人的亚群获得的 ONTARGET 分析数据并且评估人口统计并且基线特征,依从,功效,并且在在 1159 个高风险的病人全部的 China.Methods A 的使随机化的病人的不同治疗策略的安全被使随机化进三个治疗组:与 390 分配了收到 telmisartan 的 80 mg, 385 分配了收到 ramipril 的 10 mg, 384 分配了收到两学习药。中部的后续时期是 4.3 years.Results 中国病人的吝啬的年龄是 65.6 年, 73.6% 病人是男性的。有在在中国的基线的 stroke/transient ischemic 攻击的病人的比例是多于全部学习人口(47.7% 对 20.9%) 的 two times。在中国病人,学习药的永久中止的比例在 telmisartan 组由于咳嗽是 0.5% ,它多不到那在联合或 ramipril 组。在在中国病人的三个治疗组之中的主要结果的发生没有重要差别。更多的击比在全部学习人口(8.5% 对 4.5%) 发生在中国病人。更大的收缩血压减小( -9.8 mmHg ),并且更多的肾的功能失败比在 ramipril 或 telmisartan 组(2.6%对1.6%和1.0%)在那里的 .Conclusions 不是 ONTARGET 的结果关于主要结果的发生在中国病人和全部学习人口之间不同的证据的在联合治疗组被注意,特别地安全。对学习药的依从好。从 ONTARGET 的证据显示在 ONTARGET 的治疗策略对在中国的病人适用。 | YU Li-tian ZHU Jun TAN Hui-qiong WANG Guo-gan Koon K. Teo LIU Li-sheng | 2011 | Chinese Medical Journal2011，，12： | 5 |
| 20 | Medical therapy for clinical benign prostatic hyperplasia:α1 Antagonists,5α reductase inhibitors and their combination显示文摘Medical therapy for clinical benign prostatic hyperplasia(BPH)has advanced significantly in the last 2 decades.Many new a1 antagonists and 5a reductase inhibitors(5ARi)are now commercially available.The practicing urologist must decide on the most appropriate medication for his patients,taking into consideration various factors like efficacy,dosing regime,adverse effects,cost,patient’s socioeconomic background,expectations,drug availability and his own clinical experience.The use of combination therapy added further to the complexity in clinical judgment when prescribing.We highlight some of the key points in prescribing a1 antagonists,5ARi and their combination,based on our viewpoints and experience as urologists in an Asian clinical setting. | Cheuk Fan Shum Weida Lau Chang Peng Colin Teo | 2017 | Asian Journal of Urology2017，4，3： | 4 |
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