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| 1 | Endothelial progenitor cells in cardiovascular diseases显示文摘Endothelial dysfunction has been associated with the development of atherosclerosis and cardiovascular diseases. Adult endothelial progenitor cells(EPCs) are derived from hematopoietic stem cells and are capable of forming new blood vessels through a process of vas-culogenesis. There are studies which report correlations between circulating EPCs and cardiovascular risk fac-tors. There are also studies on how pharmacotherapies may influence levels of circulating EPCs. In this review, we discuss the potential role of endothelial progenitor cells as both diagnostic and prognostic biomarkers. In addition, we look at the interaction between cardio-vascular pharmacotherapies and endothelial progenitor cells. We also discuss how EPCs can be used directly and indirectly as a therapeutic agent. Finally, we evalu-ate the challenges facing EPC research and how these may be overcome. | Poay Sian Sabrina Lee Kian Keong Poh | 2014 | World Journal of Stem Cells2014，6，3： | 22 |
| 2 | Control of hybrid AC/DC microgrid under islanding operational conditions显示文摘This paper presents control methods for hybrid AC/DC microgrid under islanding operation condition.The control schemes for AC sub-microgrid and DC sub-microgrid are investigated according to the power sharing requirement and operational reliability.In addition,the key control schemes of interlinking converter with DC-link capacitor or energy storage,which will devote to the proper power sharing between AC and DC sub-microgrids to maintain AC and DC side voltage stable,is reviewed.Combining the specific control methods developed for AC and DC sub-microgrids with interlinking converter,the whole hybrid AC/DC microgrid can manage the power flow transferred between sub-microgrids for improving on the operational quality and efficiency. | Guangqian DING Feng GAO Song ZHANG Poh Chiang LOH Frede BLAABJERG | 2014 | Journal of Modern Power Systems and Clean Energy2014，2，3： | 23 |
| 3 | 不平衡负载工况下三相变流器有源功率解耦控制显示文摘三相电压源型变流器(VSC)对于微电网的稳定运行有着重要的作用。然而,孤岛工况下带三相不平衡负载运行时,交流侧产生的二次脉动功率耦合至直流侧,导致系统的工作性能降低并影响系统的寿命。针对该问题,在二次功率脉动分析的基础上,提出了一种基于虚拟三相瞬时功率的解耦控制策略,通过控制虚拟三相瞬时功率脉动分量为0,在不增加开关器件的情况下,利用LCL滤波器中电容提供负载所需二次脉动功率,实现交直流侧二次脉动功率解耦。在此基础上进一步分析了该拓扑结构直流侧所需的最低电压以及电流应力影响因素。最后仿真和实验结果均表明所提控制策略可以较好地实现功率解耦控制,直流侧源电流二次脉动分量大大减小,有利于提高系统控制性能和实现直流侧电容轻量化。 | 许泽富 唐芬 周家宇 辛振 Poh Chiang Loh | 2019 | 电网技术2019，43，3： | 11 |
| 4 | Systematic review of the outcomes of surgical resection for intermediate and advanced Barcelona Clinic Liver Cancer stage hepatocellular carcinoma:A critical appraisal of the evidence显示文摘AIM To perform a systematic review to determine the survival outcomes after curative resection of intermediate and advanced hepatocellular carcinomas(HCC).METHODS A systematic review of the published literature was performed using the PubM ed database from 1 st January 1999 to 31 st Dec 2014 to identify studies that reported outcomes of liver resection as the primary curative treatment for Barcelona Clinic Liver Cancer(BCLC) stage B or C HCC. The primary end point was to determine the overall survival(OS) and disease free survival(DFS) of liver resection of HCC in BCLC stage B or C in patients with adequate liver reserve(i.e., Child's A or B status). The secondary end points were to assess the morbidity and mortality of liver resection in large HCC(defined as lesions larger than 10 cm in diameter) and to compare the OS and DFS after surgical resection of solitary vs multifocal HCC.RESULTS We identified 74 articles which met the inclusion criteria and were analyzed in this systematic review. Analysis of the resection outcomes of the included studies were grouped according to(1) BCLC stage B or C HCC,(2) Size of HCC and(3) multifocal tumors. The median 5-year OS of BCLC stage B was 38.7%(range 10.0-57.0); while the median 5-year OS of BCLC stage C was 20.0%(range 0.0-42.0). The collective median 5-year OS of both stages was 27.9%(0.0-57.0). In examining the morbidity and mortality following liver resection in large HCC, the pooled RR for morbidity [RR(95%CI) = 1.00(0.76-1.31)] and mortality [RR(95%CI) = 1.15(0.73-1.80)] were not significant. Within the spectrum of BCLC B and C lesions, tumors greater than 10 cm were reported to have median 5-year OS of 33.0% and multifocal lesions 54.0%.CONCLUSION Indication for surgical resection should be extended to BCLC stage B lesions in selected patients. Further studies are needed to stratify stage C lesions for resection. | Ye Xin Koh Hwee Leong Tan Weng Kit Lye Juinn Huar Kam Adrian Kah Heng Chiow Siong San Tan Su Pin Choo Alexander Yaw Fui Chung Brian Kim Poh Goh | 2018 | World Journal of Hepatology2018，10，6： | 10 |
| 5 | 直流微电网群分层控制策略显示文摘为了确保直流微电网群可靠运行,提出一种分层控制策略。在第1层控制下,各子微网独立稳定运行,分布式电源均采用最大功率跟踪控制,储能系统通过动态调整负荷功率的分配来均衡储能单元的荷电状态。第2层控制根据各子微网的母线电压控制微电网群在不同运行状态之间无缝平滑切换,并通过管理不同子微网之间的功率流动来改善母线电压质量。最后利用Matlab/Simulink搭建微电网群仿真模型,仿真结果表明该控制策略可以提高微电网群的稳定性并可改善供电电压质量。 | 米阳 吴彦伟 符杨 王成山 POH Chiang Loh | 2017 | 电力系统及其自动化学报2017，29，12： | 9 |
| 6 | 双Boost单相逆变器并网控制策略显示文摘双Boost单相逆变器能够实现单级升压逆变,适用于分布式能源并网发电领域。针对其并网控制策略难以兼顾高性能的动态响应特性以及交直流侧电能质量的问题,在分析双Boost单相逆变器并网工作原理、功率解耦以及谐振机理的基础上,提出了一种由单并网电流环、功率解耦和有源阻尼组成且具有对称结构的并网控制策略,分析并介绍了各部分控制原理。最后,仿真和实验结果表明,所提控制策略具有动态响应速度快、并网电流质量高、直流侧无二次功率脉动等优点。 | 黄松伟 唐芬 肖琦 刘京斗 辛振 Poh Chiang LOH | 2018 | 电力系统自动化2018，42，16： | 8 |
| 7 | Carcinogenesis of nasopharyngeal carcinoma:an alternate hypothetical mechanism显示文摘Current proposed mechanisms implicate both early and latent Epstein-Barr virus(EBV)infection in the carcinogenic cascade,whereas epidemiological studies have always associated nasopharyngeal carcinoma(NPC)with early childhood EBV infection and with chronic ear,nose,and sinus conditions.Moreover,most patients with NPC present with IgA antibody titers to EBV capsid antigen(VCA-lgA),which can precede actual tumor presentation by several years.If early childhood EBV infection indeed constitutes a key event in NPC carcinogenesis,one would have to explain the inability to detect the virus in normal nasopharyngeal epithelium of patients at a high risk for EBV infection.It is perhaps possible that EBV resides within the salivary glands,instead of the epithelium,during latency.This claim is indirectly supported by observations that the East Asian phenotype shares the characteristics of an increased susceptibility to NPC and immature salivary gland morphogenesis,the latter of which is influenced by the association of salivary gland morphogenesis with an evolutionary variant of the human ectodysplasin receptor gene(EDAR),EDARV370A.Whether the immature salivary gland represents a more favorable nidus for EBV is uncertain,but in patients with infectious mononucleosis,EBV has been isolated in this anatomical organ.The presence of EBV-induced lymphoepitheliomas in the salivary glands and lungs further addresses the possibility of submucosal spread of the virus.Adding to the fact that the fossa of Rosen Muller contains a transformative zone active only in the first decade of life,one might be tempted to speculate the possibility of an alternative carcinogenic cascade for NPC that is perhaps not dissimilar to the model of human papillomavirus and cervical cancer. | Sharon Shuxian Poh Melvin Lee Kiang Chua Joseph T.S.Wee | 2016 | Chinese Journal of Cancer2016，35，1： | 8 |
| 8 | 三电平并网变流器中点电位自平衡特性分析及拓扑改进显示文摘传统三电平并网变流器中点电位自平衡时间较长,中点电位可能产生较大偏移,使并网电流低次谐波增加,常需采用中点电位控制防止中点电位偏移。为充分发挥拓扑的自平衡能力,省去中点电位控制算法,文中首先定量分析了载波同相层叠脉宽调制输出电压的谐波分布特性,在此基础上,给出了传统拓扑中点电位自平衡机理及影响因素。针对传统拓扑自平衡时间的制约因素,提出了三电平并网变流器中点电位自平衡改进拓扑,通过新增零序通路在载波频率处产生串联谐振,减小阻抗,从而显著提升自平衡速度。最后,仿真和实验结果表明改进拓扑能快速有效地将中点电位稳定于直流侧电源中点,且自平衡速度不受直流侧电压不平衡度影响,中点电位平衡后并网电流质量较高。相对传统拓扑,自平衡速度提高10倍以上,与传统中点电位控制速度相当,因此,可省去中点电位控制。尽管所提拓扑需增加一个小电容,但其无需电压偏差检测,无需增加或调整控制算法,适用于全功率因数范围,易于实现。 | 陈鹏飞 唐芬 吴学智 武亮亮 王玮 Poh Chiang LOH | 2019 | 电力系统自动化2019，43，24： | 7 |
| 9 | 低开关频率下LCL型并网变流器复矢量分析及改进解耦控制显示文摘同步旋转坐标系(dq)下的比例积分控制在并网变流器中得到广泛应用。由于滤波器和数字延迟的dq模型均存在轴间耦合并且两者相互影响,低开关频率下LCL型并网变流器的建模和解耦控制变得极具挑战。针对该问题,在对同步旋转坐标系下的LCL型并网变流器采用复矢量进行建模的基础上,通过双边频响特性曲线和零极点图对传统状态反馈和相位补偿进行了系统分析,揭示了不同位置相位补偿对系统相位裕度和解耦性能的影响关系,在此基础上提出了一种改进解耦控制方法,通过在状态反馈环内和调节器输出端依次设计相位补偿,在有效调节和改善动态性能的同时保证系统具有较好的解耦性能。最后,仿真及实验结果表明所提方法具有很好的解耦效果,同时能有效减小系统超调量和调节时间。 | 肖琦 唐芬 辛振 周家宇 陈鹏飞 Poh Chiang Loh 姜久春 | 2018 | 电网技术2018，42，9： | 7 |
| 10 | 浅谈医疗服务的“BEU”理念显示文摘本文以患者心理与生理需求为基础 ,以满足患者的需求为出发点和归宿点 ,提出医疗服务的“BEU”理念。并结合具体的医疗服务实践 ,谈了实践“BEU”理念的几点体会。 | 徐克成 左建生 Law Lee Poh 汪道远 | 2005 | 中国交通医学杂志2005，19，1： | 5 |
| 11 | 2D几何图形整体内插的一种方法显示文摘隐含在2D几何图形之间的图形关系在图形内插中起着十分重要的作用.本文在深入研究了图形内插问题之后,提出了一种2D几何图形整体内插的思路并设计出了一种实现整体内插的算法.该算法根据内插图形所具有的特性建立反映初始图形之间相互关系的三维模型。 | LAI Poh 黄培之 | 1999 | 计算机学报1999，22，2： | 5 |
| 12 | Autonomous Power Management for Interlinked AC-DC Microgrids显示文摘The existing power management schemes for interlinked AC-DC microgrids have several operational drawbacks.Some of the existing control schemes are designed with the main objective of sharing power among the interlinked microgrids based on their loading conditions,while other schemes regulate the voltage of the interlinked microgrids without considering the specific loading conditions.However,the existing schemes cannot achieve both objectives efficiently.To address these issues,an autonomous power management scheme is proposed,which explicitly considers the specific loading condition of the DC microgrid before importing power from the interlinked AC microgrid.This strategy enables voltage regulation in the DC microgrid,and also reduces the number of converters in operation.The proposed scheme is fully autonomous while it retains the plug-nplay features for generators and tie-converters.The performance of the proposed control scheme has been validated under different operating scenarios.The results demonstrate the effectiveness of the proposed scheme in managing the power deficit in the DC microgrid efficiently and autonomously while maintaining the better voltage regulation in the DC microgrid. | Inam Ullah Nutkani Lasantha Meegahapola Loh Poh Chiang Andrew Frede Blaabjerg | 2018 | CSEE Journal of Power and Energy Systems2018，4，1： | 4 |
| 13 | Data-Driven Structural Design Optimization for Petal-Shaped Auxetics Using Isogeometric Analysis显示文摘Focusing on the structural optimization of auxetic materials using data-driven methods,a back-propagation neural network(BPNN)based design framework is developed for petal-shaped auxetics using isogeometric analysis.Adopting a NURBSbased parametric modelling scheme with a small number of design variables,the highly nonlinear relation between the input geometry variables and the effective material properties is obtained using BPNN-based fitting method,and demonstrated in this work to give high accuracy and efficiency.Such BPNN-based fitting functions also enable an easy analytical sensitivity analysis,in contrast to the generally complex procedures of typical shape and size sensitivity approaches. | Yingjun Wang Zhongyuan Liao Shengyu Shi Zhenpei Wang Leong Hien Poh | 2020 | Computer Modeling in Engineering & Sciences2020，，2： | 4 |
| 14 | A survey of data envelopment analysis in energy and environmental studies显示文摘 | P. Zhou B.W. Ang K.L. Poh | 2007 | European Journal of Operational Research2007，，1： | 3 |
| 15 | Enhancing endothelial progenitor cell for clinical use显示文摘Circulating endothelial progenitor cells(EPCs) have been demonstrated to correlate negatively with vascularendothelial dysfunction and cardiovascular risk factors. However, translation of basic research into the clinical practice has been limited by the lack of unambiguous and consistent definitions of EPCs and reduced EPC cell number and function in subjects requiring them for clinical use. This article critically reviews the definition of EPCs based on commonly used protocols, their value as a biomarker of cardiovascular risk factor in subjects with cardiovascular disease, and strategies to enhance EPCs for treatment of ischemic diseases. | Lei Ye Kian-Keong Poh | 2015 | World Journal of Stem Cells2015，7，6： | 3 |
| 16 | Structural Design Optimization Using Isogeometric Analysis: A Comprehensive Review显示文摘Isogeometric analysis(IGA),an approach that integrates CAE into conventional CAD design tools,has been used in structural optimization for 10 years,with plenty of excellent research results.This paper provides a comprehensive review on isogeometric shape and topology optimization,with a brief coverage of size optimization.For isogeometric shape optimization,attention is focused on the parametrization methods,mesh updating schemes and shape sensitivity analyses.Some interesting observations,e.g.the popularity of using direct(differential)method for shape sensitivity analysis and the possibility of developing a large scale,seamlessly integrated analysis-design platform,are discussed in the framework of isogeometric shape optimization.For isogeometric topology optimization(ITO),we discuss different types of ITOs,e.g.ITO using SIMP(Solid Isotropic Material with Penalization)method,ITO using level set method,ITO using moving morphable com-ponents(MMC),ITO with phase field model,etc.,their technical details and applications such as the spline filter,multi-resolution approach,multi-material problems and stress con-strained problems.In addition to the review in the last 10 years,the current developmental trend of isogeometric structural optimization is discussed. | Yingjun Wang Zhenpei Wang Zhaohui Xia Leong Hien Poh | 2018 | Computer Modeling in Engineering & Sciences2018，，12： | 3 |
| 17 | Structural and luminescence studies of europium ions in lithium aluminium borophosphate glasses显示文摘Eu3+ doped borophosphate glasses with the chemical composition 20Li2O-30Al2O3-10B2O3-40P2O5-xEu2O3(where x=0.05 mol.%, 0.1 mol.%, 1.0 mol.%, 1.5 mol.% and 2.0 mol.%) were prepared by conventional melt quenching technique. The structural and luminescence properties of the prepared Eu3+ doped borophosphate glasses were studied and compared with reported results. The XRD pattern showed the amorphous nature of the prepared glasses. Whereas, the FTIR spectra revealed the vibrational modes in the prepared glasses. The bonding parameters( β and ?) were calculated through the excitation spectra. Judd–Ofelt(J–O) intensity parameters were calculated from the emission spectra and were used to determine transition probability(A), stimulated emission cross-section(σE P), radiative lifetime(τR) and branching ratios(βexp) for the transition 5D0→7Fj(j=1, 2, 3 and 4) of Eu3+ ions. Furthermore, the luminescence intensity ratio(R) of 5D0→7F2 to 5D0→7F1 transition was also calculated. Transition 5D0→7F2 had the highest value of stimulated emission cross-section and branching ratios and the results were comparable with the reported values. This indicated that the present glass is promising host material for Eu3+ doped fiber amplifiers. | Poh Sum Wong Ming Hua Wan Rosli Hussin Hendrik O.Lintang Salasiah Endud | 2014 | Journal of Rare Earths2014，32，7： | 3 |
| 18 | Innovations in chronic anal fissure treatment:A systematic review显示文摘A chronic anal fissure is a common perianal condition.This review aims to evaluate both existing and new therapies in the treatment of chronic fissures.Pharmacological therapies such as glyceryl trinitrate(GTN),Diltiazem ointment and Botulinum toxin provide a relatively non-invasive option,but with higher recurrence rates.Lateral sphincterotomy remains the gold standard for treatment.Anal dilatation has no role in treatment.New therapies include perineal support devices,Gonyautoxin injection,fissurectomy,fissurotomy,sphincterolysis,and flap procedures.Further research is required comparing these new therapies with existing established therapies.This paper recommends initial pharmacological therapy with GTN or Diltiazem ointment with Botulinum toxin as a possible second line pharmacological therapy.Perineal support may offer a new dimension in improving healing rates.Lateral sphincterotomy should be offered if pharmacological therapy fails.New therapies are not suitable as first line treatments,though they can be considered if conventional treatment fails. | Aaron Poh Kok-Yang Tan Francis Seow-Choen | 2010 | World Journal of Gastrointestinal Surgery2010，2，7： | 3 |
| 19 | The largest outbreak of hand; foot and mouth disease in Singapore in 2008: The role of enterovirus 71 and coxsackievirus A strains显示文摘 | Yan Wu Andrea Yeo M.C. Phoon E.L. Tan C.L. Poh S.H. Quak Vincent T.K. Chow | 2010 | International Journal of Infectious Diseases2010，，： | 3 |
| 20 | 夏热冬冷地区低碳住宅设计策略效用的量化分析显示文摘根据国家节能和能效标准及相关研究,从围护结构设计和空调器制冷采暖两个方面总结出夏热冬冷地区低碳住宅的设计策略并采集数据,按能耗水平的不同赋值于4组情景假设,再运用Design Builder Energy Plus模拟软件计算空调器能耗值和CO2排放值。结果显示,当采取节能减排措施后,该地区低碳住宅的空调器能耗(含采暖)区间为14.0~4.9kWh(m2·a),CO2排放区间为11.5~4.0kg(m2·a)。 | 刘君怡 李保峰 Khee Poh Lam | 2010 | 建筑学报2010，，S1： | 3 |
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