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| 1 | Bilirubin in coronary artery disease:Cytotoxic or protective?显示文摘Bilirubin has traditionally been considered a cytotoxic waste product.However,recent studies have shown bilirubin to have anti-oxidant,anti-inflammatory,vasodilatory,anti-apoptotic and anti-proliferative functions.These properties potentially confer bilirubin a new role of protection especially in coronary artery disease(CAD),which is a low grade inflammatory process exacerbated by oxidative stress.In fact,recent literature reports an inverse relationship between serum concentration of bilirubin and the presence of CAD.In this article,we review the current literature exploring the association between levels of bilirubin and risk of CAD.We conclude that current evidence is inconclusive regarding the protective effect of bilirubin on CAD.A causal relationship between low serum bilirubin level and increased risk of CAD is not currently established. | Nancy Gupta Tavankit Singh Rahul Chaudhary Sushil K Garg Gurprataap Singh Sandhu Varun Mittal Rahul Gupta Roxana Bodin Sachin Sule | 2016 | World Journal of Gastrointestinal Pharmacology and Therapeutics2016，7，4： | 14 |
| 2 | Texture analysis on parametric maps derived from dynamic contrast-enhanced magnetic resonance imaging in head and neck cancer显示文摘AIM: To investigate the merits of texture analysis on parametric maps derived from pharmacokinetic modeling with dynamic contrast-enhanced magnetic resonance imaging(DCE-MRI) as imaging biomarkers for the prediction of treatment response in patients with head and neck squamous cell carcinoma(HNSCC). METHODS: In this retrospective study,19 HNSCC patients underwent pre- and intra-treatment DCEMRI scans at a 1.5T MRI scanner. All patients had chemo-radiation treatment. Pharmacokinetic modeling was performed on the acquired DCE-MRI images,generating maps of volume transfer rate(Ktrans) and volume fraction of the extravascular extracellular space(ve). Image texture analysis was then employed on maps of Ktrans and ve,generating two texture measures: Energy(E) and homogeneity.RESULTS: No significant changes were found for the mean and standard deviation for Ktrans and ve between pre- and intra-treatment(P > 0.09). Texture analysis revealed that the imaging biomarker E of ve was significantly higher in intra-treatment scans,relative to pretreatment scans(P < 0.04). CONCLUSION: Chemo-radiation treatment in HNSCC significantly reduces the heterogeneity of tumors. | Jacobus FA Jansen Yonggang Lu Gaorav Gupta Nancy Y Lee Hilda E Stambuk Yousef Mazaheri Joseph O Deasy Amita Shukla-Dave | 2016 | World Journal of Radiology2016，8，1： | 5 |
| 3 | Changing trends in the incidence, stage, survival, and screen-detection of colorectal cancer: A population-based study显示文摘 | Amit K. Gupta L. Joseph Melton Gloria M. Petersen Lawrence J. Timmons Santhi Swaroop Vege William S. Harmsen Nancy N. Diehl Alan R. Zinsmeister David A. Ahlquist | 2005 | Clinical Gastroenterology and Hepatology2005，，2： | 1 |
| 4 | Technological innovations: a framework for communicating diffusion effects 显示文摘 | FRANKLING J CARTER JR A THANI J AMBULINGAMA VIPUL K GUPTA NANCY MELONE | 2001 | Information & Management2001，，38： | 1 |
| 5 | Trends in Acute Myocardial Infarction in Young Patients and Differences by Sex and Race, 2001 to 2010显示文摘 | Aakriti Gupta Yongfei Wang John A. Spertus Mary Geda Nancy Lorenze Chileshe Nkonde-Price Gail D’Onofrio Judith H. Lichtman Harlan M. Krumholz | 2014 | Journal of the American College of Cardiology2014，，： | 1 |
| 6 | Connecting microRNA Genes to the Core Transcriptional Regulatory Circuitry of Embryonic Stem Cells显示文摘 | Alexander Marson Stuart S. Levine Megan F. Cole Garrett M. Frampton Tobias Brambrink Sarah Johnstone Matthew G. Guenther Wendy K. Johnston Marius Wernig Jamie Newman J. Mauro Calabrese Lucas M. Dennis Thomas L. Volkert Sumeet Gupta Jennifer Love Nancy Han | 2008 | Cell2008，，3： | 1 |
| 7 | Intrauterine growth restriction: comparison of American College of Obstetricians and Gynecologists practice bulletin with other national guidelines显示文摘 | Suneet P. Chauhan Lata M. Gupta Nancy W. Hendrix Vincenzo Berghella | 2009 | American Journal of Obstetrics and Gynecology2009，，4： | 1 |
| 8 | Connecting microRNA Genes to the Core Transcriptional Regulatory Circuitry of Embryonic Stem Cells显示文摘 | Alexander Marson Stuart S. Levine Megan F. Cole Garrett M. Frampton Tobias Brambrink Sarah Johnstone Matthew G. Guenther Wendy K. Johnston Marius Wernig Jamie Newman J. Mauro Calabrese Lucas M. Dennis Thomas L. Volkert Sumeet Gupta Jennifer Love Nancy Han | 2008 | Cell2008，，3： | 1 |
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