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| 1 | ATP-binding cassette subfamily B member 1 (ABCB1) and subfamily C member 10(ABCC1O) are not primary resistance factors for cabazitaxel显示文摘Introduction:ATP-binding cassette subfamily B member 1(ABCB1) and subfamily C member 10(ABCCIO) proteins are efflux transporters that couple the energy derived from ATP hydrolysis to the translocation of toxic substances and chemotherapeutic drugs out of cells.Cabazitaxel is a novel taxane that differs from paclitaxel by its lower affinity for ATP-binding cassette(ABC) transporters.Methods:We determined the effects of cabazitaxel,a novel tubulin-binding taxane,and paclitaxel on paclitaxelresistant,ABCB1-overexpressing KB-C2 and LLC-MDR1-WT cells and paclitaxel-resistant,ABCC10-overexpressing HEK293/ABCC10 cells by calculating the degree of drug resistance and measuring ATPase activity of the ABCB1 transporter.Results:Decreased resistance to cabazitaxel compared with paclitaxel was observed in KB-C2,LLC-MDR1-WT,and HEK293/ABCC10 cells.Moreover,cabazitaxel had low efficacy,whereas paclitaxel had high efficacy in stimulating the ATPase activity of ABCB1,indicating a direct interaction of both drugs with the transporter.Conclusion:ABCB1 and ABCC10 are not primary resistance factors for cabazitaxel compared with paclitaxel,suggesting that cabazitaxel may have a low affinity for these efflux transporters. | Rishil J Kathawala Yi-Jun Wang Suneet Shukla Yun-Kai Zhang Saeed Alqahtani Amal Kaddoumi Suresh V Ambudkar Charles R Ashby Jr Zhe-Sheng Chen | 2015 | Chinese Journal of Cancer2015，34，3： | 4 |
| 2 | Chronological age when health care transition skills are mastered in adolescents/young adults with inflammatory bowel disease显示文摘AIM To describe the longitudinal course of acquisition of healthcare transition skills among adolescents and young adults with inflammatory bowel diseases.METHODS We recruited adolescents and young adults(AYA) with inflammatory bowel diseases(IBD), from the pediatric IBD clinic at the University of North Carolina. Participants completed the TRx ANSITION Scale? at least once during the study period(2006-2015). We used the electronic medical record to extract participants' clinical and demographic data. We used ordinary least square regressions with robust standard error clustered at patient level to explore the variations in the levels and growths of healthcare transition readiness.RESULTS Our sample(n = 144) ranged in age from 14-22 years. Age was significantly and positively associated with both the level and growth of TRx ANSITION Scale? scores(P < 0.01). Many healthcare transition(HCT) skills were acquired between ages 12 and 14 years, but others were not mastered until after age 18, including self-management skills.CONCLUSION This is one of the first studies to describe the longitudinal course of HCT skill acquisition among AYA with IBD, providing benchmarks for evaluating transition interventions. | Natalie Stollon Yi Zhong Maria Ferris Suneet Bhansali Brian Pitts Eniko Rak Maureen Kelly Sandra Kim Miranda AL van Tilburg | 2017 | World Journal of Gastroenterology2017，23，18： | 2 |
| 3 | Evidence-based surgery for cesarean delivery显示文摘 | Vincenzo Berghella Jason K. Baxter Suneet P. Chauhan | 2005 | American Journal of Obstetrics and Gynecology2005，，5： | 1 |
| 4 | Predictive Value of Microvolt T-Wave Alternans in Patients With Left Ventricular Dysfunction显示文摘 | Daniel J. Cantillon Kenneth M. Stein Steven M. Markowitz Suneet Mittal Bindi K. Shah Daniel P. Morin Eran S. Zacks Matthew Janik Shaun Ageno Andreas C. Mauer Bruce B. Lerman Sei Iwai | 2007 | Journal of the American College of Cardiology2007，，： | 1 |
| 5 | Analytical solution to transient heat conduction in polar coordinates with multiple layers in radial direction显示文摘 | Suneet Singh Prashant K. Jain Rizwan-uddin | 2007 | International Journal of Thermal Sciences2007，，3： | 1 |
| 6 | Prediction of hemor2rhage at cesarean delivery显示文摘 | Robert N Suneet PC Steven PC | 1994 | Obstet Gynecol1994，83，： | 1 |
| 7 | SPICE simulation of surface acoustic wave interdigital transducers 显示文摘 | Bhattacharyya A B Tuli Suneet Maiumdar Swati | 1995 | IEEE Transactions on Ultrasonics Ferroelectrics and Control1995，42，4： | 1 |
| 8 | Analytical solution to transient asymmetric heat conduction in a mutilayer annulus显示文摘 | PRASHANT K J SUNEET S RIZWAN U | 2009 | Journal of Heat Transfer2009，131，1： | 1 |
| 9 | Analytical solution to transient heat conduction in polar coordinates with multiple layers in radial direction显示文摘 | SUNEET S PRASHANT K J RIZWAN U | 2008 | International Journal of Thermal Sciences2008，47，3： | 1 |
| 10 | Female sex hormones and rat dural vasodilatation to CGRP,periarterial electrical and capsaicin显示文摘 | Gupta Saurabh Villalon Carlos M Mehrotra Suneet | | 0，，02： | 1 |
| 11 | Evidence-based surgery for cesarean delivery显示文摘 | Vincenzo Berghella Jason K. Baxter Suneet P. Chauhan | 2005 | American Journal of Obstetrics and Gynecology2005，，5： | 1 |
| 12 | A Circuit Simulation Compatible Surface Acoustic Wave Interdigital Transducer Macro-Model显示文摘 | | 2004 | IEEE Transactions on Ultrasonics Ferroelectrics and Control2004，51，7： | 1 |
| 13 | A comparison of the pulsed, lock-in and frequency mo- dulated thermography nondestructive evaluation techniques 显示文摘 | Krishnendu Chatterjeea Suneet Tuli Simon G Pickering | 2011 | NDT E Int2011，44，： | 1 |
| 14 | Effect of doping of cesium carbonate on electron transport in Tris(8-hydroxyquinolinato) aluminum显示文摘 | Priyanka Tyagi Ritu Srivastava Arunandan Kumar Suneet Tuli M.N. Kamalasanan | 2013 | Organic Electronics2013，，5： | 1 |
| 15 | Doppler assessment of the fetus with intrauterine growth restriction显示文摘 | Eliza Berkley Suneet P. Chauhan Alfred Abuhamad | 2012 | American Journal of Obstetrics and Gynecology2012，，4： | 1 |
| 16 | Prediction of hemorrhage at cesarean delivery显示文摘 | Robert N Suneet PC Steven PC | 1994 | Obstet Gynecol1994，83，： | 1 |
| 17 | Electro-thermal Modelling and Analysis for Estimation of Defect Parameters by Stepped Infrared Thermography显示文摘 | Rajesh Gupta Suneet Tuli | 2005 | NDT&E International2005，，38： | 1 |
| 18 | Packet Classification for Core Routers: Is there an alternative to CAMs 显示文摘 | FLORIN B SUNEET S GEORGE Y | 2003 | IEEE INFOCOM2003，，5： | 1 |
| 19 | Neonatal organ system injury in acute birth asphyxia sufficient to result in neonatal encephalopathy显示文摘 | Suneet P. Chauhan Everett F. Magann John C. Morrison Suneet P. Chauhan Everett F. Magann John C. Morrison Suneet P. Chauhan Everett F. Magann John C. Morrison | 2003 | Obstetrics & Gynecology2003，，1： | 1 |
| 20 | Use of fetal pulse oximetry among high-rlsk women in labor: a randomized clinical trial 显示文摘 | Chad K K Erin E C Suneet P C | 2005 | Am J Ohstet Gynecol2005，192，6： | 1 |
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