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| 1 | ACS Nano:新型纳米颗粒运输系统或能克服CRISPR基因编辑障碍显示文摘近日,一项刊登在国际杂志ACSNano上的研究报告中,来自马萨诸塞大学阿默斯特分校的研究人员通过研究利用纳米颗粒设计出了一种新系统能够帮助CRISPR/Cas9系统跨过细胞膜进入到细胞核中,同时还能够避免被细胞器所捕获。研究者Rubul Mout说道,CRISPR由两种组分组成,包括名为Cas9的剪刀样蛋白和名为sgRNA的RNA分子,sgRNA分子能够引导Cas9进入到靶点位置。 | Rubul Mout† Moumita Ray† Gulen Yesilbag Tonga Yi-Wei Lee Tristan Tay Kanae Sasaki Vincent M. Rotello | 2017 | 现代生物医学进展2017，17，14： | 3 |
| 2 | Bioautography and its scope in the field of natural product chemistry显示文摘Medicinal plants, vegetables and fruits are the sources of huge number of bioactive lead/scaffolds with therapeutic and nutraceutical importance. Bioautography is a means of target-directed isolation of active molecules on chromatogram. Organic solvents employed in chromatographic separation process can be completely removed before biological detection because these solvents cause inactivation of enzymes and/or death of living organisms. They offer a rapid and easy identification of bioactive lead/scaffolds in complex matrices of plant extracts. Bioautography is a technique to isolate hit(s)/lead(s) by employing a suitable chromatographic process followed by a biological detection system. This review critically describes the methodologies to identify antimicrobial, antioxidant, enzyme inhibitor lead/scaffolds by employing bioautography. A significant number of examples have been incorporated to authenticate the methodologies. | Saikat Dewanjee Moumita Gangopadhyay Niloy Bhattacharya Ritu Khanra Tarun K.Dua | 2015 | Journal of Pharmaceutical Analysis2015，5，2： | 3 |
| 3 | Si/Si C-based DD hetero-structure IMPATTs as MM-wave power-source:a generalized large-signal analysis显示文摘A full-scale, self-consistent, non-linear, large-signal model of double-drift hetero-structure IMPATT diode with general doping profile is derived. This newly developed model, for the first time, has been used to analyze the large-signal characteristics of hexagonal Si C-based double-drift IMPATT diode. Considering the fabrication feasibility, the authors have studied the large-signal characteristics of Si/Si C-based hetero-structure devices. Under small-voltage modulation( 2%, i.e. small-signal conditions) results are in good agreement with calculations done using a linearised small-signal model. The large-signal values of the diode's negative conductance(5 106S/m2/,susceptance(10.4 107S/m2/, average breakdown voltage(207.6 V), and power generating efficiency(15%, RF power: 25.0 W at 94 GHz) are obtained as a function of oscillation amplitude(50% of DC breakdown voltage) for a fixed average current density. The large-signal calculations exhibit power and efficiency saturation for large-signal(> 50%) voltage modulation and thereafter decrease gradually with further increasing voltage-modulation. This generalized large-signal formulation is applicable for all types of IMPATT structures with distributed and narrow avalanche zones. The simulator is made more realistic by incorporating the space-charge effects, realistic field and temperature dependent material parameters in Si and Si C. The electric field snap-shots and the large-signal impedance and admittance of the diode with current excitation are expressed in closed loop form. This study will act as a guide for researchers to fabricate a high-power Si/Si C-based IMPATT for possible application in high-power MM-wave communication systems. | Moumita Mukherjee P.R.Tripathy S.P.Pati | 2015 | Journal of Semiconductors2015，36，6： | 3 |
| 4 | Understanding the physiological functions of the host xenobiotic-sensing nuclear receptors PXR and CAR on the gut microbiome using genetically modified mice显示文摘Pharmacological activation of the xenobiotic-sensing nuclear receptors pregnane X receptor(PXR) and constitutive androstane receptor(CAR) is well-known to increase drug metabolism and reduce inflammation. Little is known regarding their physiological functions on the gut microbiome. In this study, we discovered bivalent hormetic functions of PXR/CAR modulating the richness of the gut microbiome using genetically engineered mice. The absence of PXR or CAR increased microbial richness, and absence of both receptors synergistically increased microbial richness. PXR and CAR deficiency increased the pro-inflammatory bacteria Helicobacteraceae and Helicobacter. Deficiency in both PXR and CAR increased the relative abundance of Lactobacillus, which has bile salt hydrolase activity, corresponding to decreased primary taurine-conjugated bile acids(BAs) in feces, which may lead to higher internal burden of taurine and unconjugated BAs, both of which are linked to inflammation, oxidative stress, and cytotoxicity. The basal effect of PXR/CAR on the gut microbiome was distinct from pharmacological and toxicological activation of these receptors. Common PXR/CAR-targeted bacteria were identified, the majority of which were suppressed by these receptors. h PXR-TG mice had a distinct microbial profile as compared to wild-type mice. This study is the first to unveil the basal functions of PXR and CAR on the gut microbiome. | Mallory Little Moumita Dutta Hao Li Adam Matson Xiaojian Shi Gabby Mascarinas Bruk Molla Kris Weigel Haiwei Gu Sridhar Mani Julia Yue Cui | 2022 | Acta Pharmaceutica Sinica B2022，12，2： | 2 |
| 5 | Antidiabetic activity of Diospyros peregrina fruit: Effect on hyperglycemia, hyperlipidemia and augmented oxidative stress in experimental type 2 diabetes显示文摘 | Saikat Dewanjee Anup K. Das Ranabir Sahu Moumita Gangopadhyay | 2009 | Food and Chemical Toxicology2009，，10： | 2 |
| 6 | Action of pelargonidin on hyperglycemia and oxidative damage in diabetic rats:Implication for glycation-induced hemoglobin modification显示文摘 | Moumita Roy Subhrojit Sen Abhay Sankar Chakraborti | 2008 | Life Scinences2008，82，21： | 1 |
| 7 | A comprehensive study on enhanced characteristics of modified polylactic acid based versatile biopolymer显示文摘 | Moumita Bishai Swarnalok De Basudam Adhikari Rintu Banerjee | 2014 | European Polymer Journal2014，，： | 1 |
| 8 | Development of SSR markers and construction of a linkage map in jute显示文摘 | MOUMITA DAS SUMANA BANERJEE RAMAN DHARIWAL SHAILENDRA VYAS REYAZUL MIR NILADRI TOPDAR AVIJIT KUNDU JITENDRA KHURANA AKHILESH TYAGI DEBABRATA SARKAR MOHIT SINHA HARINDRA BALYAN PUSHPENDRA GUPTA | 2012 | Journal of Genetics2012，，1： | 1 |
| 9 | Theoretical approach to explore the production routes of astatine radionu-clides显示文摘 | Moumita M Susanta L | 2009 | Physical Review C2009，79，02： | 1 |
| 10 | RNAi mediated silencing of lipoxygenase gene to maintain rice grain quality and viability during storage显示文摘 | Dipak Gayen Nusrat Ali Moumita Ganguly Soumitra Paul Karabi Datta Swapan K. Datta | 2014 | Plant Cell, Tissue and Organ Culture (PCTOC)2014，，2： | 1 |
| 11 | A novel approach for change detection of remotely sensed images using semi-supervised multiple classifier system显示文摘 | Moumita Roy Susmita Ghosh Ashish Ghosh | 2014 | Information Science2014，269，10： | 1 |
| 12 | Study of the influence of some pol- ymeric additives as viscosity index improvers and pour point de- pressants-synthesis and characterization显示文摘 | PRANAB G MOUMITA D | 2014 | Journal of Petroleum Science and Engineering2014，119，： | 1 |
| 13 | Comparison of gonadotropin - releasing hormone agonist with GnRH antagonist in polycystic ovary syndrome patients undergoing in vitro fertilization cycle: Retrospective analysis from a tertiary center and review of literature 显示文摘 | Singh N NAHA Moumita Malhotra N | 2014 | J Hum Reprod Sci2014，7，1： | 1 |
| 14 | Influence of plant growth regulators on callus mediated regeneration and secondary metabolites synthesis in Withania somnifera显示文摘 | Nilanjan C Debarupa B Moumita G | 2003 | Physiol Mol Biol Plant2003，19，： | 1 |
| 15 | Effect of dephasing on electron transport in a molecular wire: Green’s function approach显示文摘 | Moumita Dey Santanu K. Maiti S.N. Karmakar | 2011 | Organic Electronics2011，，6： | 1 |
| 16 | Synthesis, crystal structure, and magnetic properties of a new tetranuelear Cu ( II ) Schiff base compound显示文摘 | Moumita B Guillaume P Javier T | 2009 | Inorg Chim Acta2009，8，362： | 1 |
| 17 | Silica-Immobilized CuI: An Efficient Reusable Catalyst for Three-Component Coupling Reaction of Aldehyde, Amine and Alkyne显示文摘 | Pravin Likhar Sarabindu Roy Moumita Roy M. Subhas M. Kantam Rajib De | 2007 | Synlett2007，，14： | 1 |
| 18 | Tyrosinase and oculardiseases: Some novel thoughts on the molecular basis ofoculocutaneous albinism type I 显示文摘 | KunalRay Moumita C Mainak S | 2007 | Progress in Retinal EyeRe2007，26，4： | 1 |
| 19 | Trinary registers and counters using savart plate and spatial light modulator for optical computation in multivalued logic显示文摘Registers and counters are the most important devices in any system of computations.In this paper we have communicated the trinary registers and counters in modified trinary number(MTN) system.It is suitable for the optical computing and other applications in multivalued logic system.Here the savart plate and spatial light modulator(SLM) based optoelectronic circuits have been used to exploit the optical tree architecture(OTA) in optical interconnection network. | Amal K Ghosh Moumita Raul | 2009 | Optoelectronics Letters2009，5，3： | 1 |
| 20 | Deposition and characterization of TiAISiN nanocomposite coatings prepared by reactive pulsed direct current unbalanced magnetron sputtering 显示文摘 | Harish C B Moumita G Shashidhara | 2010 | Applied Surface Science2010，256，21： | 1 |
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