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| 1 | Potential antibacterial activity of berberine against multi drug resistant enterovirulent Escherichia coli isolated from yaks(Poephagus grunniens) with haemorrhagic diarrhoea显示文摘Objective:To evaluate the antimicrobial efficacy of berberine,a plant alkaloid.Methods:Five multi-drug resistant(MDR) STEC/EPEC and five MDR ETEC isolates from yaks with haemorrhagic diarrhoea were selected for the study.Antibacterial activity of berberine was evaluated by broth dilution and disc diffusion methods.The binding kinetics of berberine to DNA and protein was also enumerated.Results:For both categories of enterovirulent Escherichia coli(E.roli) isolates, berberine displayed the antibaclerial effect in a dose dependent manner.The MIC50 of berberine chloride for STEC/EPEC isolates varied from 2.07μM to 3.6μM with a mean of(2.95±0.33)μM where as for ETEC strains it varied from 1.75 to 1.96μM with a mean of(1.87±0.03)μM. Berberine bind more tightly with double helix DNA with Bmax and Kd of(24.68±2.62) and(357.8±57.8),respectively.Berberine reacted with protein in comparatively loose manner with Bmax and Kd of(18.9±3.83) and <286.2±113.6),respectively.Conclusions:The results indicate clearly that berberine may serve as a good antibacterial against multi drug resistant E.coli. | Samiran Bandyopadhyay Pabitra H Patra Achintya Mahanti Dipak K Mondal Premanshu Dandapat Subhasis Bandyopadhyay Indranil Samanta Chandan Lodh Asit K Bera Debasish Bhattacharyya Mihir Sarkar Kishore K Baruah | 2013 | Asian Pacific Journal of Tropical Medicine2013，6，4： | 11 |
| 2 | Awareness of and attitudes towards infertility and its treatment: a cross-sectional survey of men in a United States primary care population显示文摘以前的研究在不孕的治疗描述了种族、社会经济的不同。象态度和了解那样的耐心的因素可能正在贡献因素。因为主要照顾经常是用作一个条目进药的另外的区域的背景,我们寻求了在主要照顾背景评估人男不孕的态度和了解。做这,我们从在亚特兰大等待房间的二个主要照顾诊所在 210 个人执行了人对人的健康问题的态度的代表性的调查,乔治娅。调查与 closed-ended 问题项目是自我管理的并且是在长度的约 20 min。走近的 310 个人, 210 同意参与并且归还了完成的调查。总的来说, 52% 人说他们是 “ very”或 “ somewhat”熟悉不孕并且 25% 为不孕熟悉了治疗。一些人为男不孕作为治疗听说了外科(21%) 和药(35%) 。有条件的了解和熟悉在高社会经济的地位人是更大的(即有收入 > 的学院毕业生或那些; $100 k 每年) 但是没在 multivariate 分析上由种族不同。对不孕的态度与是更可能的显示不孕是一个严重条件,并且相信它减少的非白种人人一起由种族变化了,到担心不孕一个人的 quality-of-life。因此,了解的缺乏,然而并非否定态度,可以在不孕的治疗贡献以前描述的不同。 | Robert S Gerhard Chad WM Ritenour Michael Goodman Dipak Vashi Wayland Hsiao | 2014 | Asian Journal of Andrology2014，16，6： | 7 |
| 3 | Interferon-γ: Promising therapeutic target in atherosclerosis显示文摘Atherosclerosis is a chronic inflammatory disorder of the vasculature and is the primary cause of cardiovascular disease(CVD). CVD is currently the world's leading cause of death and the numbers are predicted to rise further because of a global increase in risk factors such as diabetes and obesity. Current therapies such as statins have had a major impact in reducing mortality from CVD. However, there is a marked residual CVD risk in patients on statin therapy. It is therefore important to understand the molecular basis of this disease in detail and to develop alternative novel therapeutics. Interferon-γ(IFN-γ) is a pro-inflammatory cytokine that is often regarded as a master regulator of atherosclerosis development. IFN-γ is able to influence several key steps during atherosclerosis development, including pro-inflammatory gene expression, the recruitment of monocytes from the blood to the activated arterial endothelium and plaque stability. This central role of IFN-γ makes it a promising therapeutic target. The purpose of this editorial is to describe the key role IFN-γ plays during atherosclerosis development, as well as discuss potential strategies to target it therapeutically. | Joe WE Moss Dipak P Ramji | 2015 | World Journal of Experimental Medicine2015，5，3： | 7 |
| 4 | Microstructure studies of air-plasma-spray-deposited CoNiCrAlY coatings before and after thermal cyclic loading for high-temperature application显示文摘In the present study, bond-coats for thermal barrier coatings were deposited via air plasma spraying(APS) techniques onto Inconel 800 and Hastelloy C-276 alloy substrates. Scanning electron microscopy(SEM), transmission electron microscopy(TEM), X-ray diffraction(XRD), and atomic force microscopy(AFM) were used to investigate the phases and microstructure of the as-sprayed, APS-deposited Co Ni Cr Al Y bond-coatings. The aim of this work was to study the suitability of the bond-coat materials for high temperature applications. Confirmation of nanoscale grains of the γ/γ′-phase was obtained by TEM, high-resolution TEM, and AFM. We concluded that these changes result from the plastic deformation of the bond-coat during the deposition, resulting in Co Ni Cr Al Y bond-coatings with excellent thermal cyclic resistance suitable for use in high-temperature applications. Cyclic oxidative stability was observed to also depend on the underlying metallic alloy substrate. | Dipak Kumar K.N.Pandey Dipak Kumar Das | 2016 | International Journal of Minerals,Metallurgy and Materials2016，23，8： | 6 |
| 5 | 糜子芽苗期对干旱胁迫的响应及抗旱种质鉴定显示文摘为了了解内蒙古现存糜子种质资源的抗旱性,研究糜子在PEG-6000模拟干旱胁迫下的抗旱表现,挖掘优异抗旱种质并筛选抗旱鉴定指标,以33份来源于内蒙古的糜子核心种质资源为试验对象,在PEG-6000模拟干旱胁迫下,利用相关性分析、主成分分析、平均值-标准差逐级分级法和聚类分析等方法评估了材料芽期、苗期的抗旱性。结果表明,干旱胁迫下,芽期和苗期各指标较对照组均有下降趋势,糜子芽期比苗期更易受干旱胁迫,发芽势对干旱胁迫反应最敏感,变异系数为380.4%,苗期各指标变异系数均在13.2%~67.4%。糜子多数抗性指标间呈显著或极显著相关,其中相对苗长与相对苗鲜质量之间的相关性最大,相对根长与相对根干质量的相关性最小。对33份核心种质进行了芽苗期抗旱性鉴定和分类分析,结果鉴定出乌克兰黍(00006438)和伊盟良56-2黍(00000684)芽期抗旱性最强;准旗酱黄黍(00000650)、和林红糜子(00002160)、乌克兰黍(00006438)、8311/4/5(00005884)、伊选大红黍(00002473)和达旗青糜子(00002385)等6份种质苗期抗旱性好,乌克兰黍(00006438)芽期和苗期抗旱性能均突出。 | 程冀南 李玉露 王宇卓 Santra Dipak K 王瑞云 | 2022 | 山西农业科学2022，50，7： | 6 |
| 6 | Isothermal Grain Growth of Austenite in Hypoeutectoid and Hypereutectoid Plain Carbon Steels显示文摘Grain growth kinetics of austenite in a hypoeutectoid steel(containing carbon of 0.35%)at 920 ℃ and in a hypereutectoid steel(containing carbon of 1%)at 980 ℃ for holding time ranging from 1 h to 6 h was investigated.The hypoeutectoid steel exhibited normal grain growth without solute drag hindrance with a time exponent(0.51)close to the theoretical value(0.5).However,the grain growth of austenite in the hypereutectoid steel held up to 3 h was extremely slow,characterizing by a low value of time exponent(0.08).Thereafter,a breakaway occurred and the grain growth in the hypereutectoid steel held from 3 h to 6 h progressed normally with a time exponent(0.52)close to the theoretical value(0.5). | Joydeep Maity Dipak Kumar Mondal | 2010 | Journal of Iron and Steel Research(International)2010，17，7： | 5 |
| 7 | Wireless sensor network survey显示文摘 | Jennifer Yick Biswanath Mukherjee Dipak Ghosal | 2008 | Computer Networks2008，，12： | 5 |
| 8 | Nano CuO/g-C_3N_4 sheets-based ultrafiltration membrane with enhanced interfacial affinity,antifouling and protein separation performances for water treatment application显示文摘To improve the interfacial affinity and antifouling properties of polyphenylsulfone(PPSU)membrane, nano CuO/g-C3 N4(g-CN) sheets were synthesized via facile calcination route as one pot synthesis method. The uniformly assembled nanohybrid fillers, CuO on g-CN sheets were confirmed by using XRD, TEM, EDX and FTIR analysis. The non-solvent induced phase inversion technique was used to fabricate the nanohybrid ultrafiltration(UF)membranes by doping different concentration(0.5–1 wt.%) of nano CuO/g-C_3 N_4(g-CN)sheets within the PPSU matrix. The results of contact angle, atomic force microscopy,energy-dispersive X-ray spectroscopy reveal that surface structure and physico-chemical properties of nanohybrid membrane plays lead role in solute interaction and rejection compared to bare membrane, M0. Furthermore, the interfacial affinity of membrane was explored in detail via surface free energy, spreading coefficient, wetting tension and reversible work of adhesion analysis. Nanohybrid UF membrane, with 0.5% of the filler(M1)displayed remarkable permeation flux of 202, 131 L/m2/hr for pure water and protein solution, respectively while maintaining a high protein rejection(96%). Moreover, the exceptional dispersion of the nanosheets in the polymer matrix enhanced FRR(79%) and decreased the overall resistance of M1 compared to the pristine membrane(M0). Overall results suggest that the incorporation of nano sheets is a facile modification technique which improves the comprehensive membrane performance and holds a great potential to be further explored for water treatment. | Thanigaivelan Arumugham Reshika Gnanamoorthi Amimodu Noel Jacob Kaleekkal Dipak Rana | 2019 | Journal of Environmental Sciences2019，31，8： | 4 |
| 9 | Biomimetic approach for the synthesis of N,N'-diarylsubstituted formamidines catalyzed by β-cyclodextrin in water显示文摘为 N 的合成的一条环境地良性、高度有效的 biomimetic 途径,水里的 N-diarylsubstituted formamidines 催化 -cyclodextrin 与产品的量的收益在中立状况下面被描述。-Cyclodextrin 被恢复了并且再使用。 | Dipak R.Patil Dipak S.Dalal | 2012 | Chinese Chemical Letters2012，23，10： | 4 |
| 10 | Free radicals and grape seed proanthocyanidin extract: importance in human health and disease prevention显示文摘 | Debasis Bagchi Manashi Bagchi Sidney J Stohs Dipak K Das Sidhartha D Ray Charles A Kuszynski Shantaram S Joshi Harry G Pruess | 2000 | Toxicology2000，，2： | 3 |
| 11 | A cesium fluoride promoted efficient and rapid multicomponent synthesis of functionalized 2-amino-3-cyano-4H-pyran and spirooxindole derivatives显示文摘A rapid, one-pot and highly efficient protocol for the synthesis of pharmaceutically interesting functionalized 2-amino-3-cyano-4H-pyran and spirooxindole derivatives has been developed using commercially available Cs F as a catalyst in the reaction of malononitrile and aryl aldehydes or isatins with 1,3-cyclohexanediones. The major advantages of this methodology are excellent yield at ambient temperature, very short reaction time(5–10 min), and use of an inexpensive catalyst. | Yogesh B.Wagh Yogesh A.Tayade Swapnil A.Padvi Bhupesh S.Patil Nilesh B.Patil Dipak S.Dalal | 2015 | Chinese Chemical Letters2015，26，10： | 3 |
| 12 | Synthesis of PbS-K_2La_2Ti_3O_(10) composite and its photocatalytic activity for hydrogen production | Dipak Rana | 2012 | Progress in Natural Science:Materials International2012，22，2： | 3 |
| 13 | Acanthus ilicifolius plant extract prevents DNA alterations in a transplantable Ehrlich ascites carcinoma-bearing murine model显示文摘AIM: To investigate the chemopreventive efficacy of the Indian medicinal plant Acanthus ilicifolius L Acanthaceae in a transplantable Ehrlich ascites carcinoma (EAC)- bearing murine model. METHODS: Male Swiss albino mice were divided into four groups: Group A was the untreated normal control; Group B was the EAC control mice group that received serial, intraperitoneal (ip) inoculations of rapidly proliferating 2 x 105 viable EAC cells in 0.2 mL of sterile phosphate buffered saline; Group C was the plant extract-treated group that received the aqueous leaf extract (ALE) of the plant at a dose of 2.5 mg/kg body weight by single ip injections, once daily for 10, 20 and 30 consecutive days following tumour inoculation (ALE control); and Group D was the EAC + ALE- treatment group. The chemopreventive potential of the ALE was evaluated in a murine model by studying various biological parameters and genotoxic markers, such as tumour cell count, mean survival of the animals, haematological indices, hepatocellular histology, immunohistochemical expression of liver metallothionein (MT) protein, sister-chromatid exchanges (SCEs), and DNA alterations.RESULTS: Treatment of the EAC-bearing mice with the ALE significantly (P < 0.001) reduced viable tumour cell count by 68.34% (228.7 x 106 ± 0.53) when compared to EAC control mice (72.4 x 106 ± 0.49), and restored body and organ weights almost to the normal values. ALE administration also increased (P < 0.001) mean survival of the hosts from 35 ± 3.46 d in EAC control mice to 83 ± 2.69 d in EAC + ALE-treated mice. Haematological indices also showed marked improvement with administration of ALE in EAC-bearing animals. There was a significant increase in RBC count (P < 0.001), hemoglobin percent (P < 0.001), and haematocrit value (P < 0.001) from 4.3 ± 0.12, 6.4 ± 0.93, and 17.63 ± 0.72 respectively in EAC control mice to 7.1 ± 0.13, 12.1 ± 0.77, and 30.23 ± 0.57 respectively in EAC + ALE-treated group, along with concurrent decrement (P < 0.001) in WBC count from 18.8 ± 0.54 in EAC control to 8.4 ± 0.71 in EAC + ALE. Furthermore, treatment with ALE substantially improved hepatocellular architecture and no noticeable neoplastic lesions or foci of cellular alteration were observed. Daily administration of the ALE was found to limit liver MT expression, an important marker of cell proliferation with concomitant reduction in MT immunoreactivity (62.25 ± 2.58 vs 86.24 ± 5.69, P < 0.01). ALE was also potentially effective in reducing (P < 0.001) the frequency of SCEs from 14.94 ± 2.14 in EAC control to 5.12 ± 1.16 in EAC + ALE-treated group. Finally, in comparison to the EAC control, ALE was able to suppress in vivo DNA damage by abating the generations of ‘tailed’ DNA by 53.59% (98.65 ± 2.31 vs 45.06 ± 1.14, P < 0.001), and DNA single-strand breaks (SSBs) by 38.53% (3.14 ± 0.31 vs 1.93 ± 0.23, P < 0.01) in EAC-bearing murine liver. CONCLUSION: Our data indicate that, ALE is beneficial in restoring haematological and hepatic histological profiles and in lengthening the survival of the animals against the proliferation of ascites tumour in vivo. Finally, the chemopreventive efficacy of the ALE is manifested in limiting MT expression and in preventing DNA alterations in murine liver. The promising results of this study suggest further investigation into the chemopreventive mechanisms of the medicinal plant A. ilicifolius in vivo and in vitro. | Tridib Chakraborty Dipak Bhuniya Mary Chatterjee Mosiur Rahaman Dipak Singha Baidya Nath Chatterjee Subrata Datta Ajay Rana Kartick Samanta Sunil Srivastawa Sankar K Maitra Malay Chatterjee | 2007 | World Journal of Gastroenterology2007，13，48： | 2 |
| 14 | Wireless sensor network survey显示文摘 | Jennifer Yick Biswanath Mukherjee Dipak Ghosal | 2008 | Computer Networks2008，，12： | 2 |
| 15 | Pancreatic paraganglioma: An extremely rare entity and crucial role of immunohistochemistry for diagnosis显示文摘 | Mondita Borgohain Gayatri Gogoi Dipak Das Manjusha Biswas | 2013 | Indian Journal of Endocrinology and Metabolism2013，，5： | 2 |
| 16 | 用于白内障超声乳化训练的活体白内障动物模型(英文)显示文摘目的:制备用于白内障超声乳化训练的活体白内障动物模型。方法:狗在全身麻醉下用26号带有斜面的针刺破左眼的晶状体前囊,制备白内障模型,形成白内障后,行超声乳化手术。结果:眼部检查显示晶状体后部皮质混浊开始于穿刺术后5~7d,并于术后75d白内障全部形成,在所有的白内障形成的眼上行超声乳化手术,并植入人工晶状体,所有的狗均恢复了视力。结论:考虑到无经验的眼科医生在行白内障超声乳化手术的初始阶段引起的巨大损失,我们认为这个活的动物模型明显优于目前用于训练超声乳化手术的尸体眼。 | Sarbani Hazra Dipak K De Arup K Bose Biswarup Roy | 2008 | 国际眼科杂志2008，8，6： | 2 |
| 17 | Inference on disk-jet connection of MAXI J1836–194 from spectral analysis with the TCAF solution显示文摘Galactic transient black hole candidate(BHC)MAXI J1836–194 was discovered on 2011 Aug30,by MAXI/GSC and Swift/BAT.The source activity during this outburst continued for^3 months before entering into the quiescent state.It again became active in March 2012 and continued for another^2 months.In this paper,3-25 keV RXTE/PCA spectra from the 2011 outburst and 0.5-10.0 keV Swift/XRT data during its 2012 outburst are analyzed with the two-component advective flow(TCAF)model based fits files in XSPEC.We calculate the X-ray contributions coming from jets/outflow using a newly developed method based on the deviation of the TCAF model normalization.We also study the correlation between observed radio and estimated jet X-ray fluxes.The correlation indices(b)are found to be 1.79 and 0.61,when the 7.45 GHz Very Large Array(VLA)radio flux is correlated with the total X-ray and jet X-ray fluxes in 3-25 keV range respectively.It has been found that the jet contributes in X-rays up to a maximum of 86%during its 2011 outburst.This makes the BHC MAXI J1836–194 strongly jet dominated during the initial rising phase. | Arghajit Jana Dipak Debnath Sandip KChakrabarti Debjit Chatterjee | 2020 | Research in Astronomy and Astrophysics2020，20，3： | 2 |
| 18 | Fire monitoring in coal mines using wireless underground sensor network and interval type-2 fuzzy logic controller显示文摘From the view of underground coal mining safety system, it is extremely important to continuous monitoring of coal mines for the prompt detection of fires or related problems inspite of its uncertainty and imprecise characteristics. Therefore, evaluation and inferring the data perfectly to prevent fire related accidental risk in underground coal mining (UMC) system are very necessary. In the present article, we have proposed a novel type-2 fuzzy logic system (T2FLS) for the prediction of fire intensity and its risk assessment for risk reduction in an underground coal mine. Recently, for the observation of underground coal mines, wireless underground sensor network (WUSN) are being concerned frequently. To implement this technique IT2FLS, main functional components are sensor nodes which are installed in coal mines to accumulate different imprecise environmental data like, temperature, relative humidity, different gas concentrations etc. and these are sent to a base station which is connected to the ground observation system through network. In the present context, a WUSN based fire monitoring system is developed using fuzzy logic approach to enhance the consistency in decision making system to improve the risk chances of fire during coal mining. We have taken Mamdani IT2FLS as fuzzy model on coal mine monitoring data to consider real-time decision making (DM). It is predicted from the simulated results that the recommended system is highly acceptable and amenable in the case of fire hazard safety with compared to the wired and off-line monitoring system for UMC. Legitimacy of the suggested model is prepared using statistical analysis and multiple linear regression analysis. | Sweta Basu Sutapa Pramanik Sanghamitra Dey Gautam Panigrahi Dipak Kumar Jana | 2019 | International Journal of Coal Science & Technology2019，6，2： | 2 |
| 19 | [bmim]OH: An efficient catalyst for the synthesis of mono and bis spirooxindole derivatives in ethanol at room temperature显示文摘A rapid and efficient, one pot synthesis of spirooxindole derivatives has been attempted by threecomponent reaction of isatin, malononitrile and carbonyl compound possessing a reactive a-methylene group by using task specific ionic liquid, 1-butyl-3-methyl imidazolium hydroxide [bmim]OH as a catalyst. The important features of this methodology are straight forward route in short reaction time at room temperature and avoid any hazardous organic solvent, toxic catalyst, tedious purification step.Interestingly, this protocol is not only limited to mono-systems but also to the synthesis of newer bisspirooxindole system. The separation of the product and reusability of the catalyst are easy with excellent yield. The [bmim]OH catalyst system could be reused up to five recycles without appreciable loss of activity. | Swapnil A. Padvi Yogesh A. Tayade Yogesh B. Wagh Dipak S. Dalai | 2016 | Chinese Chemical Letters2016，27，5： | 2 |
| 20 | Photocatalytic reduction of organic pollutant under visible light by green route synthesized gold nanoparticles显示文摘We report a rapid method of green chemistry approach for synthesis of gold nanoparticles(AuNPs)using Lagerstroemia speciosa leaf extract(LSE). L. speciosa plant extract is known for its effective treatment of diabetes and kidney related problems. The green synthesis of Au NPs was complete within 30 min at 25°C. The same could also be achieved within 2 min at a higher reaction temperature(80°C). Both UV–visible spectroscopy and transmission electron microscopy results suggest that the morphology and size distribution of Au NPs are dependent on the pH of gold solution,gold concentration,volume of LSE,and reaction time and temperature. Comparison between Fourier transform infrared spectroscopy(FT-IR)spectra of LSE and the synthesized Au NPs indicate an active role of polyphenolic functional groups(from gallotannins,lagerstroemin,and corosolic acid)in the green synthesis and capping of Au NPs. The green route synthesized Au NPs show strong photocatalytic activity in the reduction of dyes viz.,methylene blue,methyl orange,bromophenol blue and bromocresol green,and 4-nitrophenol under visible light in the presence of Na BH_4. The non-toxic and cost effective LSE mediated Au NPs synthesis proposed in this study is extremely rapid compared to the other reported methods that require hours to days for complete synthesis of Au NPs using various plant extracts. Strong and stable photocatalytic behavior makes Au NPs attractive in environmental applications,particularly in the reduction of organic pollutants in wastewater. | Bharat C.Choudhary Debajyoti Paul Tarun Gupta Sandesh R.Tetgure Vaman J.Garole Amulrao U.Borse Dipak J.Garole | 2017 | Journal of Environmental Sciences2017，29，5： | 2 |
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