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1Restrictions to the application of 'diagnostic'criteria for recognizing ancient seismites显示文摘Soft-sediment deformation structures induced by seismic liquefaction and/or fluidization receive much attention in sedimentological,structural and palaeoseismic studies.The direct record of larger earthquakes is restricted to instrumental and historical data; the recognition of prehistoric earthquakes requires criteria to recognize seismites in the geological record.The areal distribution of seismites can sometimes be related to active faults since distances to the epicenter(for a given magnitude) tend to be related to the liquefaction effects of seismic shocks.The use of soft-sediment deformation structures for palaeoseismic studies has limitations,however.Hardly anything is known,for instance,about the effects that modern seismic events have on the sediments in most environments.Moreover,criteria for the recognition of seismites are still under discussion.The following characteristics seem,particularly in combination,the most reliable:(1) Soft-sediment deformation structures should occur in laterally continuous,preferably recurring horizons,separated by undeformed beds;(2) These deformation structures should be comparable with structures known to have been triggered by modern seismic activity;(3) The sedimentary basin should have experienced tectonic activity at the time when the deformations were formed; and(4) The intensity or abundance of the soft-sediment deformation structures in a presumed seismite should change laterally,depending on the distance to the epicenter.It turns out that all of these four criteria have important exceptions.(1) Soft-sediment deformation structures occurring over large lateral distances in a specific layer can be triggered also by other processes.Moreover,in environments with a low sedimentation rate,the time between successive earthquakes is often too short to allow accumulation of beds that remain undisturbed.Furthermore,total liquefaction of a sandy bed may result in the absence of deformation features.(2) No truly diagnostic soft-sediment deformation structures exist to prove seismic activity.Moreover,the final configuration of a soft-sediment deformation structure is independent of the type of trigger.(3) Seismites occur frequently in areas where seismic activity is low today.(4) The lateral changes in the intensity of soft-sediment deformation structures in seismites as a factor presumed to depend on the distances to the epicenter,pose a complicated problem.The 2012 Emilia earthquakes,for instance,affected sandy fluvial channels but not the fine-grained floodplains.It must thus be deduced that specific soft-sediment deformation structures cannot be used without additional evidence to identify seismites.In particular,the magnitude of seismic shocks and the recurrence time of main events(the most important features that allow recognition of seismites) seem to be sedimentological in nature:facies changes in space and time seem theparameters that most strongly control the occurrence,morphology,lateral extent and the vertical repetition of seismites.Massimo Moretti A.J.(Tom) van Loon 2014Journal of Palaeogeography2014,3,2:22
2Effect of follicle-stimulating hormone on sperm quality and pregnancy rate显示文摘Aim: To evaluate the possible links between ultrastructural sperm quality and the clinical pregnancy rate in infertile males treated with FSH before intracytoplasmic sperm injection (ICSI). Methods: Forty-four infertile males with idiopathic oligo-asthenozoospermia were randomly allocated to the treated (n=24) and non-treated (control,n=20) groups. Semen analysis was carried out by light and transmission electron microscopy (TEM) before and 12 weeks after FSH therapy. ICSI was performed in all couples. Results: TEM revealed a significant improvement in sperm quality after FSH treatment, particularly in men with their partners achieving clinical pregnancy. The pregnancy rate was 33% in the treated group and 20% in the control. Conclusion: Results highlight a positive role of FSH therapy in infertile males before ICSI, which was correlated with an increased pregnancy rate in treated couples.We believe that improved sperm ultrastructure after FSH therapy could positively influence the quality and early stage of embryo development, thereby increasing the probability of embryo implantation.B. Baccetti P. Piomboni E. Bruni S. Capitani L. Gambera E. Moretti K. Sterzik E. Strehler 2004Asian Journal of Andrology2004,6,2:17
3Effectiveness of chest radiography,lung ultrasound and thoracic computed tomography in the diagnosis of congestive heart failure显示文摘Hydrostatic pulmonary edema is as an abnormal in-crease in extravascular water secondary to elevatedpressure in the pulmonary circulation, due to conges-tive heart failure or intravascular volume overload.Diagnosis of hydrostatic pulmonary edema is usuallybased on clinical signs associated to conventional ra-diography findings. Interpretation of radiologic signsof cardiogenic pulmonary edema are often question-able and subject. For a bedside prompt evaluation,lung ultrasound(LUS) may assess pulmonary conges-tion through the evaluation of vertical reverberationartifacts, known as B-lines. These artifacts are relatedto multiple minimal acoustic interfaces between smallwater-rich structures and alveolar air, as it happens incase of thickened interlobular septa due to increase of extravascular lung water. The number, diffusion and in-tensity of B lines correlates with both the radiologic andinvasive estimate of extravascular lung water. The inte-gration of conventional chest radiograph with LUS canbe very helpful to obtain the correct diagnosis. Com-puted tomography(CT) is of limited use in the work upof cardiogenic pulmonary edema, due to its high cost,little use in the emergencies and radiation exposure.However, a deep knowledge of CT signs of pulmonaryedema is crucial when other similar pulmonary condi-tions may occasionally be in the differential diagnosis.Luciano Cardinale Adriano Massimiliano Priola Federica Moretti Giovanni Volpicelli 2014World Journal of Radiology2014,6,6:16
4Impact of concomitant use of proton pump inhibitors and clopidogrel or ticagrelor on clinical outcomes in patients with acute coronary syndrome显示文摘BackgroundThere 是在质子泵禁止者(PPI ) 和 clopidogrel 之间的可能的不利相互作用上的大争论。另外, PPI 的使用是否少些影响 ticagrelor 遗体的临床的功效,知道。在经皮的冠的干预(一种总线标准) .MethodsWe 回顾地从 “ 分析了数据以后,我们试图与急性冠的症候群(交流)在病人在临床的结果上决定 PPI 和 clopidogrel 或 ticagrelor 的伴随物管理的影响;真实 world” ;,国际,在 2003 和 2014 之间的多中心登记( n = 15,401 )并且在1年的合成主要端点上估计了 PPI 和 clopidogrel 或 ticagrelor 的伴随物管理的影响(所有原因死亡收到 PPI 的病人更老,更经常女性,并且是更可能的有 comorbidities。没有协会为收到 clopidogrel 的病人在 PPI 使用和主要端点之间被观察(调整 HR:1.036;95% CI:0.903-1.189 ) 或 ticagrelor (调整 HR:2.320;95% CI:0.875-6.151 )(P 相互作用 = 0.2004 ) 。同样, PPI 的使用没与所有原因死亡,重新梗塞,或与交流后面的一种总线标准的为与任何一个 clopidogrel 对待的病人或 ticagrelor.ConclusionsIn 病人的严重流血的减少的风险的增加的风险被联系, PPI 的伴随物使用没在收到 clopidogrel 或 ticagrelor 的病人与不利结果的增加的风险被联系。我们的调查结果显示与 clopidogrel 或 ticagrelor 在联合使用 PPI 是合理的,特别在有胃肠的流血的更高的风险的病人。Yan YAN Xiao WANG Jing-Yao FAN Shao-Ping NIE Sergio Raposeiras-Roubin Emad Abu-Assi Jose P Simao Henriques Fabrizio D'Ascenzo Jorge Saucedo Jose R Gonzfilez-Juanatey Stephen B Wilton Wouter J Kikkert Ivlin Nufiez-Gil Albert Ariza-Sole Xian-Tao SONG Dimitrios Alexopoulos Christoph Liebetrau Tetsuma Kawaji Claudio Moretti Zenon Huczek Toshiharu Fujii Luis C Correia Masa-aki Kawashiril Sasko Kedev 2016Journal of Geriatric Cardiology2016,13,3:12
5联合应用氯吡格雷和质子泵抑制剂对急性冠状动脉综合征患者经皮冠状动脉介入术后预后的影响显示文摘目的探讨联合应用氯吡格雷和质子泵抑制剂(PPI)对急性冠状动脉综合征(ACS)患者经皮冠状动脉介入(PCI)术后预后的影响。方法回顾性分析2003年至2014年来自10个国家(加拿大,巴西,德国,波兰,荷兰,西班牙,意大利,希腊,中国,日本)15个临床中心的ACS合并PCI术后18077例患者的临床资料。研究氯吡格雷、PPI与ACS患者PCI术后预后的关系。比较患者的基本临床特征、既往病史、生化指标、药物应用,以及终点事件的发生率情况。通过Cox回归模型进行分析及倾向性评分调整其他可能影响患者的预后因素包括人口学信息(年龄、性别)和临床指标,计算PPI这一干预因素的风险比并评价其是否能够明显影响患者的预后。结果基于国际多中心Blee MACs注册登记研究分析,排除关键数据缺失过多患者2676例。根据纳入与排除标准及倾向性评分调整整理后,再排除患者6461例,最终列队患者8940例。根据患者用药不同,将患者分为氯吡格雷+PPI组(4814例)和氯吡格雷组(4126例)。氯吡格雷+PPI组患者女性、高血压病史、高脂血症病史、糖尿病史、外周血管疾病史、既往急性心肌梗死史、慢性肾功能不全病史、消化道溃疡病史、冠状动脉旁路移植术病史、既往出血病史、恶性肿瘤病史、不稳定型心绞痛、非sT段抬高型心肌梗死、心功能Killip分级≥2级、经皮腔内冠状动脉成形术、出院后血管紧张素转换酶抑制剂/血管紧张素Ⅱ受体拮抗剂应用比例、年龄和入院时血肌酐水平明显高于氯吡格雷组[25.4%(1225/4814)比21.0%(865/4126)、59.9%(2882/4814)比49.2%(2032/4126)、48.3%(2327/4814)比42.7%(1762/4126)、26.4%(1272/4814)比22.1%(910/4126)、8.0%(386/4814)比5.6%(231/4126)、12.3%(593/4814)比10.6%(436/4126)、2.0%(98/4814)比0.7%(30/4126)、2.3%(112/4814)比1.0%(42/4126)、3.6%(172/4814)比2.2%(92/4126)、4.5%(219/4814)比3.0%(123/4126)、8.0%(387/4814)比4.7%(193/4126)、13.4%(644/4814)比9.1%(374/4126)、29.1%(1400/4814)比15.9%(656/4126)、14.5%(699/4814)比11.2%(462/4126)、56.0%(2697/4814)比55.7%(2300/4126)、75.5%(3633/4814)比68.6%(2829/4126)、(66±12)岁比(61±13)岁、(10±6)mg/L比(9±4)mg/L];且入院时血红蛋白水平和出院后β受体阻滞剂应用比例明显低于氯吡格雷组[(138±19)g/L比(141±16)g/L、80.6%(3880/4814)比83.1%(3428/4126)],差异均有统计学意义(均P〈0.05)。调整前,氯吡格雷+PPI组主要终点事件(全因死亡/再发心肌梗死/出血)发生率明显高于氯吡格雷组,差异有统计学意义(风险比为1.331,95%置信区间为1.161-1.524)。调整后,氯吡格雷+PPI组主要终点事件(全因死亡/再发心肌梗死/出血)发生率与氯吡格雷组比较,差异无统计学意义(风险比为1.036,95%置信区间为0.903-1.189)。结论ACS患者PCI术后联合应用PPI与氯吡格雷是合理的,尤其在胃肠道出血高危患者中。严研 王晓 范婧尧 聂绍平 Sergio Raposeiras-Roubin Emad Abu-Assi Jose Paulo Simao Henriques Fabrizio D'Ascenzo Jorge Saucedo Jose Ramon Gonzalez-Juanatey Stephen B. Wilton Wouter J. Kikkert Ivan Nunez-Gil Albert Ariza-Sole Dimitrios Alexopoulos Christoph Liebetrau Testuma Kawaji Claudio Moretti Zenon Huczek Toshiharu Fujii Luis Claudio Correia Masa-aki Kawashiri Sasko Kedev 2017中国医药2017,12,2:10
6Bone alterations in inflammatory bowel diseases显示文摘Inflammatory bowel diseases(IBDs)are characterized by a multifactorial partially unknown etiology that involves genetic,immunological and environmental factors.Up to 50%of IBD patients experience at least one extraintestinal manifestation;among them is the involvement of bone density which is referred to as metabolic bone disease(MBD),including osteopenia and osteoporosis.Bone alterations in IBDs population appear to have a multifactorial etiology:Decreased physical activity,inflammation-related bone resorption,multiple intestinal resections,dietary malabsorption of minerals and vitamin D deficiency,genetic factors,gut-bone immune signaling interaction,steroid treatment,microbiota and pathogenic micro-organisms interaction,and dietary malabsorption of minerals,that,all together or individually,may contribute to the alteration of bone mineral density.This review aims to summarize the prevalence and pathophysiology of metabolic bone alterations in IBD subjects outlining the main risk factors of bone fragility.We also want to underline the role of the screening and prophylaxis of bone alterations in Crohn’s disease and ulcerative colitis patients and the importance of treating appropriately MBD.Dolores Sgambato Francesca Gimigliano Cristiana De Musis Antimo Moretti Giuseppe Toro Emanuele Ferrante Agnese Miranda Domenico De Mauro Lorenzo Romano Giovanni Iolascon Marco Romano 2019World Journal of Clinical Cases2019,7,15:8
7Helicobacter pylori infection and gastric carcinoma:Not all the strains and patients are alike显示文摘Gastric carcinoma(GC) develops in only 1%-3% of Helicobacter pylori(H. pylori) infected people. The role in GC formation of the bacterial genotypes, gene polymorphisms and host's factors may therefore be important. The risk of GC is enhanced when individuals are infected by strains expressing the oncoprotein CagA, in particular if CagA has a high number of repeats containing the EPIYA sequence in its C'-terminal variable region or particular amino acid sequences flank the EPIYA motifs. H. pylori infection triggers an inflammatory response characterised by an increased secretion of some chemokines by immunocytes and colonised gastric epithelial cells; these molecules are especially constituted by proteins composing the interleukin-1beta(IL-1β) group and tumour necrosis factor-alpha(TNF-α). Polymorphisms in the promoter regions of genes encoding these molecules, could account for high concentrations of IL-1β and TNF-α in the gastric mucosa, which may cause hypochlorhydria and eventually GC. Inconsistent results have been attained with other haplotypes of inflammatory and anti-inflammatory cytokines. Genomic mechanisms of GC development are mainly based on chromosomal or microsatellite instability(MSI) and deregulation of signalling transduction pathways. H. pylori infection may induce DNA instability and breaks of double-strand DNA in gastric mucocytes. Different H. pylori strains seem to differently increase the risk of cancer development run by the host. Certain H. pylori genotypes(such as the cagA positive) induce high degrees of chronic inflammation and determine an increase of mutagenesis rate, oxidative-stress, mismatch repair mechanisms, down-regulation of base excision and genetic instability, as well as generation of reactive oxygen species that modulate apoptosis; these phenomena may end to trigger or concur to GC development.natale figura luigi marano elena moretti antonio ponzetto 2016World Journal of Gastrointestinal Oncology2016,8,1:8
8Hyperglycemia in acute ischemic stroke: physiopathological and therapeutic complexity显示文摘Diabetes mellitus and associated chronic hyperglycemia enhance the risk of acute ischemic stroke and lead to worsened clinical outcome and increased mortality. However, post-stroke hyperglycemia is also present in a number of non-diabetic patients after acute ischemic stroke, presumably as a stress response. The aim of this review is to summarize the main effects of hyperglycemia when associated to ischemic injury in acute stroke patients, highlighting the clinical and neurological outcomes in these conditions and after the administration of the currently approved pharmacological treatment, i.e. insulin. The disappointing results of the clinical trials on insulin(including the hypoglycemic events) demand a change of strategy based on more focused therapies. Starting from the comprehensive evaluation of the physiopathological alterations occurring in the ischemic brain during hyperglycemic conditions, the effects of various classes of glucose-lowering drugs are reviewed, such as glucose-like peptide-1 receptor agonists, DPP-4 inhibitors and sodium glucose cotransporter 2 inhibitors, in the perspective of overcoming the up-to-date limitations and of evaluating the effectiveness of new potential therapeutic strategies.Federica Ferrari Antonio Moretti Roberto Federico Villa 2022Neural Regeneration Research2022,17,2:7
9Pathophysiology, clinical features and radiological findings of differentiation syndrome/all-trans-retinoic acid syndrome显示文摘In acute promyelocytic leukemia, differentiation thera-py based on all-trans-retinoic acid can be complicated by the development of a differentiation syndrome(DS). DS is a life-threatening complication, characterized by respiratory distress, unexplained fever, weight gain, interstitial lung infiltrates, pleural or pericardial effusions, hypotension and acute renal failure. The diagnosis of DS is made on clinical grounds and has proven to be difficult, because none of the symptoms is pathognomonic for the syndrome without any definitive diagnostic criteria. As DS can have subtle signs and symptoms at presentation but progress rapidly, end-stage DS clinical picture resembles the acute respiratory distress syndrome with extremely poor prognosis; so it is of absolute importance to be conscious of these complications and initiate therapy as soon as it was suspected. The radiologic appearance resembles the typical features of cardiogenic pulmonary edema. Diagnosis of DS remains a great skill for radiologists and haematologist but it is of an utmost importance the cooperation in suspect DS, detect the early signs of DS, examine the patients' behaviour and rapidly detect the complications.Luciano Cardinale Francesco Asteggiano Federica Moretti Federico Torre Stefano Ulisciani Carmen Fava Giovanna Rege-Cambrin 2014World Journal of Radiology2014,6,8:6
10Spectral and Energy Efficiency of Line-of-Sight OAM-MIMO Communication Systems显示文摘Not only high spectral efficiency(SE)but also high energy efficiency(EE)are required for future wireless communication systems.Radio orbital angular momentum(OAM)provides a new perspective of mode multiplexing to improve SE.However,there are few studies on the EE performance of OAM mode multiplexing.In this paper,we investigate the SE and EE of a misaligned uniform concentric circle array(UCCA)-based multi-carrier multimode OAM and multiple-input multiple-output(MCMM-OAM-MIMO)system in the line-ofsight(LoS)channel,in which two transceiver architectures implemented by radio frequency(RF)analog synthesis and baseband digital synthesis are considered.The distance and angle of arrival(AoA)estimation are utilized for channel estimation and signal detection,whose training overhead is much less than that of traditional MIMO systems.Simulation results validate that the UCCA-based MCMM-OAM-MIMO system is superior to conventional MIMOOFDM system in the EE and SE performances.Rui Chen Hong Zhou Wen-Xuan Long Marco Moretti 2020China Communications2020,17,9:6
11P2Y12受体抑制剂联合质子泵抑制剂对急性冠脉综合征患者缺血事件影响的临床分析显示文摘目的本研究旨在分析P2Y12受体抑制剂联合质子泵抑制剂(PPI)治疗对经皮冠状动脉介入(PCI)术后的急性冠脉综合征患者缺血事件的影响。方法基于国际多中心回顾性注册登记研究,纳入2003至2014年因急性冠脉综合征人院行PCI术的患者,分为PPI组及非PPI组并随访1年,主要临床终点为全因死亡/再发心肌梗死的复合终点。根据P2Y12受体抑制剂种类,将入组患者分为氯吡格雷组及替格瑞洛组,并比较不同药物与PPI联用发生临床终点事件的风险。结果研究入选9429例患者,PPI组占54.8%,具有更多高危因素。Cox回归结果提示PPI组较非PPI组全因死亡/再发心肌梗死复合事件的发生差异无统计学意义(HR1.00,95%CI 0.86—1.18)。根据P2Y12抑制剂种类不同分为氯吡格雷组和替格瑞洛组,不同P2Y12受体抑制剂联用PPI较未联用PPI患者的临床终点无差异,联用PPI的氯吡格雷组与替格瑞洛组的临床终点差异也无统计学意义。结论急性冠脉综合征患者PPI与P2Y12受体抑制剂联用不增加全因死亡和再发心肌梗死风险,尤其PPI联用氯吡格雷在患者的缺血事件上与替格瑞洛比较差异无统计学意义。冯斯婷 严妍 范婧尧 王晓 郑文 聂绍平 Sergio Raposeiras-Roubin Emad Abu-Assi Jose P Simao Henriques Fabrizio D' Ascenzo Jorge Saucedo Jose R Conzalez-Juanatey Stephen B Wilton Wouter J Kikkert Ivan Nunez-Gil Albert Ariza-Sole Dimitrios Alexopoulos Christoph Liebetrau Tetsuma Kawaji Claudio Moretti Zenon Huczek Toshiharu Fujii Luis C Correia Masa-aki Kawashiri Sasko Kedev 2016中华医学杂志2016,96,33:6
12Localization of AKAP4 and tubulin proteins in sperm with reduced motility显示文摘瞄准:表现屏蔽,与 A-kinase 抛锚蛋白质有关 4 (AKAP4 ) 并且导管素蛋白质,在有不在或严重地减少的活动性的精子组织以便检测含纤维的鞘和 axonemal 的地位。方法:免疫细胞化学导管素学习,用作积极控制,并且 AKAP4 被执行检测存在和在不同精子样品的这些蛋白质的分发。精子的词法特征被传播电子显微镜(TEM ) 学习,结果用在以前的研究报导的一个公式被详细描述。PCR 在从外部血淋巴细胞提取分析 Akap4 和 Akap3 基因的部分序列的 DNA 上被执行。结果:导管素和 AKAP4 的 Immunolabelling 显示出不同模式,它导致了我们把病人划分成组。在组Ⅰ, AKAP4 和导管素的缺席被揭示,尽管这些病人没在 Akap4/Akap3 有约束力的地点显示出改变。TEM 评估加亮那坏死的高存在与全部的精子无法移动被联系。在组Ⅱ,一个常规 AKAP4 和导管素信号是在场的,尽管活动性被减少, TEM 分析揭示了未成熟的存在。在组Ⅲ,一个弱 AKAP4 标签与正常在联系了,染色的导管素和减少的活动性被观察,含纤维的鞘的严重组织的破坏被 TEM 加亮。结论:当在精子活动性的 AKAP4 的角色是不清楚的时,不在或弱的标记 AKAP4 似乎与不在或弱的精子活动性被联系。Elena Moretti Giacomo Scapigliati Nicola Antonio Pascarelli Baccio Baccetti Giulia Collodel 2007Asian Journal of Andrology2007,9,5:6
13Can Helicobacter pylori infection influence human reproduction?显示文摘Helicobacter pylori(H.pylori)infection could be associated with extra-digestive diseases.Here,we report the evidences concerning the decrease in reproductive potential occurring in individuals infected by H.pylori,especially by strains expressing CagA.This infection is more prevalent in individuals with fertility disorders.Infected women have anti-H.pylori antibodies in cervical mucus and follicular fluid that may decrease sperm motility and cross react immunologically with spermatozoa,conceivably hampering the oocyte/sperm fusion.Infection by CagA positive organisms enhances the risk of preeclampsia,which is a main cause of foetus death.These findings are supported by the results of experimental infections of pregnant mice,which may cause reabsorption of a high number of foetuses and alter the balance between Th1 and Th2 cell response.Infected men have decreased sperm motility,viability and numbers of normally shaped sperm and augmented systemic levels of inflammatory cytokines,such as TNF-α,which may damage spermatozoa.In countries where parasitic infestation is endemic,detrimental effects of infection upon spermatozoa may not occur,because the immune response to parasites could determine a switch from a predominant Th1 type to Th2 type lymphocytes,with production of anti-inflammatory cytokines.In conclusion,the evidences gathered until now should be taken into consideration for future studies aiming to explore the possible role of H.pylori infection on human reproduction.Elena Moretti Natale Figura Giulia Collodel Antonio Ponzetto 2014World Journal of Gastroenterology2014,20,19:6
14Hepatorenal syndrome: Update on diagnosis and treatment显示文摘Acute kidney injury(AKI) is a common complication in patients with end-stage liver disease and advanced cirrhosis regardless of the underlying cause. Hepatorenal syndrome(HRS), a functional form of kidney failure, is one of the many possible causes of AKI. HRS is potentially reversible but involves highly complex pathogenetic mechanisms and equally complex clinical and therapeutic management. Once HRS has developed, it has a very poor prognosis. This review focuses on the diagnostic approach to HRS and discusses the therapeutic protocols currently adopted in clinical practice.Olga Baraldi Chiara Valentini Gabriele Donati Giorgia Comai Vania Cuna Irene Capelli Maria Laura Angelini Maria Ilaria Moretti Andrea Angeletti Fabio Piscaglia Gaetano La Manna 2015World Journal of Nephrology2015,4,5:5
1518,X,Y aneuploidies and transmission electron microscopy studies in spermatozoa from five carriers of different reciprocal translocations显示文摘我们与不同平衡相互的 translocations 从五个不肥沃的人分析了呼喊的精子贡献染色体的 meiotic 分离的学习 18, X 和 Y 并且另外由传播评估精子形态学电子显微镜学(TEM ) 分析。常规淋巴细胞 karyotype 分析加亮不同相互的平衡 translocations:t (12; 13 ) , t (4; 9 ) , t (X; 8 ) , t (8; 10 ) 并且 t (3; 16 ) 。精液分析被光和 TEM 执行。在 situ 杂交的荧光为染色体用 centromeric 探针在精子原子核上直接被执行 18, X 和 Y。在现在的学习考虑的平衡相互的 translocations 的搬运人显示出精子病理的一个很类似的模式:apoptosis 和未成熟的传播存在。所有病人显示出 meiotic 分离精神错乱,由特别地与第一个 meiotic 部门的失败有关的精子 diploidies 和性染色体 disomies 的存在加亮。然而,染色体 18 aneuploidy 的增加的发生从 t 在精子被检测(X; 8 ) 并且 t (8; 10 ) 搬运人。我们也从象 t 那样的性染色体报导了价值(X; 8 ) ,尽管 X 染色体涉及 translocation。因为有相互的 translocations 和 spermatogenetic 缺陷的病人是 intracytoplasmic 精子注射周期的候选人,精子参数,并且特别地 aneuploidy 的水平的学习评价,将在风险为夫妇提供更好的信息并且将在整个 meiotic 过程上为 chromosomal 重新整理的效果的更好的理解在文学贡献数据并且,特别地在没涉及 translocation 的染色体上。Elena Moretti Nicola Antonio Pascarelli Valentina Giannerini Michela Geminiani Cecilia Anichini Giulia Collodel 2009Asian Journal of Andrology2009,11,3:4
16Does education improve citizenship? Evidence from the United States and the United Kingdom显示文摘Kevin Milligan Enrico Moretti Philip Oreopoulos 2004Journal of Public Economics2004,,9:3
17欧洲和中国的心脏与肾脏远程缺血预适应研究:一项随机对照试验显示文摘远程缺血预适应(remote ischemic preconditioning,RIPC)对经皮冠状动脉介入治疗(percutaneous coronary intervention,PCI)术后造影剂肾病(contrast-induced nephropathy,CIN)的潜在保护作用尚待确定。该研究为双盲、随机、安慰剂对照的多中心研究,纳入年龄〈85岁,肾清除率为30~60mL/(min·1.73m^2)的有临床适应证的患者,除了直接PCI外均按1∶1给予RIPC或标准治疗。主要终点是CIN的发生率。次要终点是围手术期心肌梗死(peri-procedural myocardial infarction,PMI)的发生率。刘青 叶鹏 Moretti C Cerrato E Cavallero E Lin S Rossi ML Picchi A Sanguineti F Ugo F Palazzuoli A Bertaina M Presbitero P Shao-Liang C Pozzi R Giammaria M Limbruno U Lefèvre T Gasparetto V Garbo R OmedèP Sheiban I Escaned J Biondi-Zoccai G Gaita F Perl L D'Ascenzo F 2018中华高血压杂志2018,26,4:3
18A Promising Technology for 6G Wireless Networks:Intelligent Refl ecting Surface显示文摘The intelligent information society,which is highly digitized,intelligence inspired,and globally data driven,will be deployed in the next decade.The next 6G wireless communication networks are the key to achieve this grand blueprint,which is expected to connect everything,provide full dimensional wireless coverage and integrate all functions to support full-vertical applications.Recent research reveals that intelligent reflecting surface(IRS)with wireless environment control capability is a promising technology for 6G networks.Specifically,IRS can intelligently control the wavefront,e.g.,the phase,amplitude,frequency,and even polarization by massive tunable elements,thus achieving fine-grained 3-D passive beamforming.In this paper,we first give a blueprint of the next 6G networks including the vision,typical scenarios,and key performance indicators(KPIs).Then,we provide an overview of IRS including the new signal model,hardware architecture,and competitive advantages in 6G networks.Besides,we discuss the potential application of IRS in the connectivity of 6G networks in detail,including intelligent and controllable wireless environment,ubiquitous connectivity,deep connectivity,and holographic connectivity.At last,we summarize the challenges of IRS application and deployment in 6G networks.As a timely review of IRS,our summary will be of interest to both researchers and practitioners engaging in IRS for 6G networks.Wenxuan Long Rui Chen Moretti Marco Wei Zhang Jiandong Li 2021Journal of Communications and Information Networks2021,6,1:2
19The role of transthoracic echocardiography in the diagnosis and management of acute type A aortic syndrome显示文摘Moreno Cecconi Fabio Chirillo Carlo Costantini Gianfranco Iacobone Ercole Lopez Raffaele Zanoli Alberto Gili Stefano Moretti Marcello Manfrin Christopher Münch Lucia Torracca Gian Piero Perna 2012American Heart Journal2012,,1:2
20Acetaldehyde Inhibits PPARγ via H 2 O 2 -Mediated c-Abl Activation in Human Hepatic Stellate Cells显示文摘Elisabetta Ceni David W. Crabb Marco Foschi Tommaso Mello Mirko Tarocchi Valentino Patussi Luca Moraldi Renato Moretti Stefano Milani Calogero Surrenti Andrea Galli 2006Gastroenterology2006,,4:2
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