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| 1 | Esophageal surgery in minimally invasive era显示文摘The widespread popularity of new surgical technologies such as laparoscopy, thoracoscopy and robotics has led many surgeons to treat esophageal diseases with these methods. The expected benefits of minimally invasivesurgery(MIS) mainly include reductions of postoperative complications, length of hospital stay, and pain and better cosmetic results. All of these benefits could potentially be of great interest when dealing with the esophagus due to the potentially severe complications that can occur after conventional surgery. Moreover, robotic platforms are expected to reduce many of the difficulties encountered during advanced laparoscopic and thoracoscopic procedures such as anastomotic reconstructions, accurate lymphadenectomies, and vascular sutures. Almost all esophageal diseases are approachable in a minimally invasive way, including diverticula, gastro-esophageal reflux disease, achalasia, perforations and cancer. Nevertheless, while the limits of MIS for benign esophageal diseases are mainly technical issues and costs, oncologic outcomes remain the cornerstone of any procedure to cure malignancies, for which the long-term results are critical. Furthermore, many of the minimally invasive esophageal operations should be compared to pharmacologic interventions and advanced pure endoscopic procedures; such a comparison requires a difficult literature analysis and leads to some confounding results of clinical trials. This review aims to examine the evidence for the use of MIS in both malignancies and more common benign disease of the esophagus, with a particular emphasis on future developments and ongoing areas of research. | lapo bencini luca moraldi ilenia bartolini andrea coratti | 2016 | World Journal of Gastrointestinal Surgery2016,8,1: | 5 |
| 2 | Acetaldehyde Inhibits PPARγ via H 2 O 2 -Mediated c-Abl Activation in Human Hepatic Stellate Cells显示文摘 | Elisabetta Ceni David W. Crabb Marco Foschi Tommaso Mello Mirko Tarocchi Valentino Patussi Luca Moraldi Renato Moretti Stefano Milani Calogero Surrenti Andrea Galli | 2006 | Gastroenterology2006,,4: | 2 |
| 3 | Treatment of slow-transit constipation with sacral nerve modulation 显示文摘 | Naldini G Martellucci J Moraldi L | 2010 | Coloreetal Dis2010,12,: | 1 |
| 4 | Palliative treatment of neoplastic strictures by self-expanding nitinol Strecker stent显示文摘 | M. Pocek F. Maspes S. Masala E. Squillaci G. Assegnati A. Moraldi G. Simonetti | 1996 | European Radiology1996,,2: | 1 |
| 5 | Functional evaluation of the interposed colon as an esophageal substitute显示文摘 | Clark J Moraldi A Moossa AR | 1976 | Ann Surg1976,183,2: | 1 |
| 6 | Functional evaluation of the interposed colon as an esophageal substitute显示文摘 | Clark J Moraldi A Moosa AR | 1976 | Ann Surg1976,183,: | 1 |
| 7 | Palliative treatment of neoplastic strictures by self-expanding nitinol Strecker stent显示文摘 | M. Pocek F. Maspes S. Masala E. Squillaci G. Assegnati A. Moraldi G. Simonetti | 1996 | European Radiology1996,,2: | 1 |
| 8 | Treatment of slow-transit constipation with sacral nerve modulation 显示文摘 | Naldini G Martellucei J Moraldi L | 2010 | Colorectal Dis2010,12,11: | 1 |
| 9 | Treatment of slow- transit constipation with sacral nerve modulation显示文摘 | Naldini G Martellucci J Moraldi L | 2010 | Colorec- tal Dis2010,12,11: | 1 |
| 10 | Impact of microbiota-immunity axis in pancreatic cancer management显示文摘The microbiota impact on human diseases is well-known,and a growing body of literature is providing evidence about the complex interplay between microbiotaimmune system-human physiology/pathology,including cancers.Together with the defined risk factors(e.g.,smoke habits,diet,diabetes,and obesity),the oral,gut,biliary,and intrapancreatic microbiota contribute to pancreatic cancer development through different pathways including the interaction with the immune system.Unfortunately,a great majority of the pancreatic cancer patients received a diagnosis in advanced stages not amenable to be radically treated and potentially cured.Given the poor pancreatic cancer prognosis,complete knowledge of these complicated relationships could help researchers better understand the disease pathogenesis and thus provide early potential noninvasive biomarkers,new therapeutic targets,and tools for risk stratification that might result in greater therapeutic possibilities and eventually in a better and longer patient survival. | Ilenia Bartolini Giulia Nannini Matteo Risaliti Francesco Matarazzo Luca Moraldi Maria Novella Ringressi Antonio Taddei Amedeo Amedei | 2022 | World Journal of Gastroenterology2022,28,32: | 0 |