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| 1 | 肺癌微创治疗新技术现状——胸腔镜在肺癌治疗中的应用显示文摘在世界范围内,胸腔镜(Video-assistedthoracoscopicsurgeryVATS)下行肺叶切除术治疗肺癌的相关经验正在逐步积累。尽管大多数肺叶切除术可在胸腔镜下完成,但目前只有不到5%的肺叶切除术通过胸腔镜完成。一些胸外科医生很关注胸腔镜手术的益处与安全性,但有些外科医生不了解如何完成胸腔镜手术方法。世界上有很多医学中心都可在胸腔镜下完成解剖学上彻底的肺叶切除术及淋巴结清扫。在我们完成的1100例胸腔镜肺叶切除术中,中位术后住院时间为3天,84.7%的患者无并发症出现。比较胸腔镜手术和开胸手术的各项研究显示微创外科治疗可减少疼痛,对术后肺功能影响较小,患者术后可较快恢复日常活动,对癌症患者而言术后生存率至少与开胸手术相当。现有数据显示多数肺癌手术可在胸腔镜下完成;胸腔镜肺叶切除术与开胸手术相比具有某些优势。 | Robert J. McKenna 罗晓阳 | 2005 | 中国癌症杂志2005，15，3： | 59 |
| 2 | 胸腔镜肺叶切除术显示文摘背景与目的:尽管14年前我们就已报道在胸腔镜下可完成解剖意义上彻底的肺叶切除和淋巴结清扫,但关于这一术式的争论以及胸外科医师们提出的如何完成这种手术的疑问,使这种术式的被接受程度受到了限制。随着对这一术式持支持态度的人不断增多,这一术式的开展也越来越广泛。本文将讨论该术式的手术技术,临床疗效,以及关于这种术式的各种争论。方法:1992—2005年间我们共进行胸腔镜肺叶切除术1315例,其中女性700例(53.2%),男性615例(46.8%),患者平均年龄71.2岁。患者术后病理诊断:良性病变53例,肺部转移性肿瘤28例,淋巴瘤5例,肺癌1015例。腺癌在原发性肺癌中占63.1%。解剖意义上彻底的肺门切除和淋巴结活检或清扫均通过观察监视器屏幕完成,切口长约5cm,不需撑开肋骨。结果:9例(0.8%)死亡(无术中死亡及出血死亡患者)。932例(84.7%)术后没有出现并发症。1100例患者中有45例(4.1%)需输血。中位住院时间3d,平均住院时间4.78d。180例(20%)患者于术后第1天或第2天出院。28例(2.5%)患者术中转为开胸手术。5例(0.57%)患者术后切口出现复发。其中2003年内,在224例肺叶切除中89%通过胸腔镜完成。结论:在胸腔镜下可完成解剖意义上彻底的肺叶切除,且并发症率和死亡率较低。术中出血及切口复发的风险很小。 | Robert J McKenna Ward Houck 罗晓阳 | 2006 | 中国癌症杂志2006，16，8： | 20 |
| 3 | A history of high-power laser research and development in the United Kingdom显示文摘The first demonstration of laser action in ruby was made in 1960 by T.H.Maiman of Hughes Research Laboratories,USA.Many laboratories worldwide began the search for lasers using different materials,operating at different wavelengths.In the UK,academia,industry and the central laboratories took up the challenge from the earliest days to develop these systems for a broad range of applications.This historical review looks at the contribution the UK has made to the advancement of the technology,the development of systems and components and their exploitation over the last 60 years. | Colin N.Danson Malcolm White John R.M.Barr Thomas Bett Peter Blyth David Bowley Ceri Brenner Robert J.Collins Neal Croxford A.E.Bucker Dangor Laurence Devereux Peter E.Dyer Anthony Dymoke-Bradshaw Christopher B.Edwards Paul Ewart Allister I.Ferguson John M.Girkin Denis R.Hall David C.Hanna Wayne Harris David I.Hillier Christopher J.Hooker Simon M.Hooker Nicholas Hopps Janet Hull David Hunt Dino A.Jaroszynski Mark Kempenaars Helmut Kessler Sir Peter L.Knight Steve Knight Adrian Knowles Ciaran L.S.Lewis Ken S.Lipton Abby Littlechild John Littlechild Peter Maggs Graeme P.A.Malcolm OBE Stuart P.D.Mangles William Martin Paul McKenna Richard O.Moore Clive Morrison Zulfikar Najmudin David Neely Geoff H.C.New Michael J.Norman Ted Paine Anthony W.Parker Rory R.Penman Geoff J.Pert Chris Pietraszewski Andrew Randewich Nadeem H.Rizvi Nigel Seddon MBE Zheng-Ming Sheng David Slater Roland A.Smith Christopher Spindloe Roy Taylor Gary Thomas John W.G.Tisch Justin S.Wark Colin Webb S.Mark Wiggins Dave Willford Trevor Winstone | 2021 | High Power Laser Science and Engineering2021，9，2： | 5 |
| 4 | 中国头针治疗小儿脑瘫(英文)显示文摘目的:观察头针治疗脑性瘫痪的疗效。方法:笔者在美国对36位脑性瘫痪儿童进行了头针治疗。选穴以足运感区、平衡区为主,根据患者个体情况,配合选择言语Ⅰ区,言语Ⅱ区,视区等,针刺过程中行针捻转后留置头针30分钟。结果:在3到20次治疗后,治愈5例,14例取得了显著疗效,14例有效,3例无效。在治疗过程中无不良反应发生。结论:目前头皮针刺已成为脑瘫治疗的首选方法,通过观察纳入病例,发现头针缓解了脑瘫患儿的肢体痉挛、运动障碍、言语不能、认知障碍等,提高了病人的生活质量,改善了身体残疾症状,部分脑瘫患者可以完全康复。这些脑瘫的病例为美国神经针灸研究院与博瑞西医大学联合研究头针治疗小儿脑瘫的临床应用奠定了良好的基础。 | 吕晓琳 郝吉顺 孙忠人 David Riley 南志忠 Brian McKenna Thomas Hodge | 2017 | World Journal of Acupuncture-Moxibustion2017，27，2： | 5 |
| 5 | SC27菌剂对福眼龙眼果实生长、产量和品质的影响显示文摘田间试验结果表明:每年土壤兑水浇施澳州SC27菌剂40和80 mL*株-1可提高龙眼产量1.1-1.6 t*hm-2,这与SC27促进土壤养分有效化,提高植株叶片中N、蛋白质、糖和淀粉含量以及提高龙眼座果数和果实膨大系数有关;SC27可以增加龙眼中17种氨基酸(尤其是人体必需氨基酸)含量,以及果实中蛋白质、糖、可溶性固形物、VC、P、Ca、Fe、Zn等含量,改善果品品质. | 施木田 FRANK Mckenna 等 | 2001 | 福建农业大学学报2001，30，4： | 4 |
| 6 | Video-Assisted Thoracic Surgery Lobectomy: Experience With 1,100 Cases显示文摘 | Robert J. McKenna Ward Houck Clark Beeman Fuller | 2006 | The Annals of Thoracic Surgery2006，，2： | 3 |
| 7 | Randomized trial of mediastinal lymph node sampling versus complete lymphadenectomy during pulmonary resection in the patient with N0 or N1 (less than hilar) non–small cell carcinoma: Results of the American College of Surgery Oncology Group Z0030 Trial显示文摘 | Gail E. Darling Mark S. Allen Paul A. Decker Karla Ballman Richard A. Malthaner Richard I. Inculet David R. Jones Robert J. McKenna Rodney J. Landreneau Valerie W. Rusch Joe B. Putnam | 2011 | The Journal of Thoracic and Cardiovascular Surgery2011，，3： | 3 |
| 8 | Laser produced electromagnetic pulses: generation, detection and mitigation显示文摘This paper provides an up-to-date review of the problems related to the generation,detection and mitigation of strong electromagnetic pulses created in the interaction of high-power,high-energy laser pulses with different types of solid targets.It includes new experimental data obtained independently at several international laboratories.The mechanisms of electromagnetic field generation are analyzed and considered as a function of the intensity and the spectral range of emissions they produce.The major emphasis is put on the GHz frequency domain,which is the most damaging for electronics and may have important applications.The physics of electromagnetic emissions in other spectral domains,in particular THz and MHz,is also discussed.The theoretical models and numerical simulations are compared with the results of experimental measurements,with special attention to the methodology of measurements and complementary diagnostics.Understanding the underlying physical processes is the basis for developing techniques to mitigate the electromagnetic threat and to harness electromagnetic emissions,which may have promising applications. | Fabrizio Consoli Vladimir TTikhonchuk Matthieu Bardon Philip Bradford David CCarroll Jakub Cikhardt Mattia Cipriani Robert JClarke Thomas ECowan Colin NDanson Riccardo De Angelis Massimo De Marco Jean-Luc Dubois Bertr Etchessahar Alejro Laso Garcia David IHillier Ales Honsa Weiman Jiang Viliam Kmetik Josef Krása Yutong Li FredériéLubrano Paul McKenna Josefine Metzkes-Ng Alexre Poyé Irene Prencipe Piotr Ra¸czka Rol ASmith Roman Vrana Nigel CWoolsey Egle Zemaityte Yihang Zhang Zhe Zhang Bernhard Zielbauer David Neely | 2020 | High Power Laser Science and Engineering2020，8，2： | 3 |
| 9 | 3T magnetic resonance neurography of pudendal nerve with cadaveric dissection correlation显示文摘AIM: To evaluate the pudendal nerve segments that could be identified on magnetic resonance neurography(MRN) before and after surgical marking of different nerve segments.METHODS: The hypothesis for this study was that pudendal nerve and its branches would be more easily seen after the surgical nerve marking. Institutional board approval was obtained. One male and one female cadaver pelvis were obtained from the anatomy board and were scanned using 3 Tesla MRI scanner using MR neurography sequences. All possible pudendal nerve branches were identified. The cadavers were then sent to the autopsy lab and were surgically dissected by a peripheral nerve surgeon and an anatomist to identify the pudendal nerve branches. Radiological markers were placed along the course of the pudendal nerve and its branches. The cadavers were then closed and rescanned using the same MRN protocol as the premarking scan. The remaining pudendal nerve branches were attempted to be identified using the radiological markers. All scans were read by an experienced musculoskeletal radiologist.RESULTS: The pre-marking MR Neurography scans clearly showed the pudendal nerve at its exit from the lumbosacral plexus in the sciatic notch, at the level of the ischial spine and in the Alcock's Canal in both cadavers. Additionally, the right hemorrhoidal branch could be identified in the male pelvis cadaver. The perineal and distal genital branches could not be identified. On post-marking scans, the markers were used as identifiable structures. The location of the perineal branch, the hemorroidal branch and the dorsal nerve to penis(in male cadaver)/clitoris(in female cadaver) could be seen. However, the visualization of these branches was suboptimal. The contralateral corresponding nerves were poorly seen despite marking on the surgical side. The nerve was best seen on axial T1W and T2W SPAIR images. The proximal segment could be seen well on 3D DW PSIF sequence. T2W SPACE was not very useful in visualization of this small nerve or its branches.CONCLUSION: Proximal pudendal nerve is easily seen on MR neurography, however it is not possible to identify distal branches of the pudendal nerve even after surgical marking. | Avneesh Chhabra Courtney A McKenna Vibhor Wadhwa Gaurav K Thawait John A Carrino Gary P Lees A Lee Dellon | 2016 | World Journal of Radiology2016，8，7： | 3 |
| 10 | 腺苷酸活化蛋白激酶病酷似肥厚性心肌病和预激综合征:自然病史 | Murphy R.T. Mogensen J. McGarry K. W.J. McKenna 吴波 | 2005 | 世界核心医学期刊文摘(心脏病学分册)2005，0，9： | 3 |
| 11 | 成人类风湿关节炎的诊断和管理:NICE指南更新概要显示文摘类风湿关节炎是一种慢性、致残的自身免疫病,主要以大小关节的滑膜炎引起肿胀、晨僵、疼痛和进行性关节破坏为特征。英国人的患病率约1%,其中约15%为重度类风湿关节炎。女性患病率约为男性的3倍。可见于任何年龄,但40~60岁好发。类风湿关节炎的早期表现为关节疼痛和肿胀。快速、准确地转诊至风湿科对实现早期缓解、预防或减少残疾至关重要。 | Alex Allen Serena Carville Frank McKenna 白明欣(译) 姚海红(审校) | 2019 | 英国医学杂志中文版2019，22，2： | 3 |
| 12 | The Cardiac Desmosome and Arrhythmogenic Cardiomyopathies: From Gene to Disease显示文摘 | Mario Delmar William J. McKenna | 2010 | Circulation Research2010，，6： | 2 |
| 13 | Video-Assisted Thoracic Surgery Sleeve Lobectomy: A Case Series显示文摘 | Ali Mahtabifard Clark B. Fuller Robert J. McKenna | 2008 | The Annals of Thoracic Surgery2008，，2： | 2 |
| 14 | Residual feed intake phenotype and gender affect the expression of key genes of the lipogenesis pathway in subcutaneous adipose tissue of beef cattle显示文摘Background: Feed accounts for up to 75% of costs in beef production systems,thus any improvement in feed efficiency(FE) will benefit the profitability of this enterprise.Residual feed intake(RFI) is a measure of FE that is independent of level of production.Adipose tissue(AT) is a major endocrine organ and the primary metabolic energy reservoir.It modulates a variety of processes related to FE such as lipid metabolism and glucose homeostasis and thus measures of inter-animal variation in adiposity are frequently included in the calculation of the RFI index.The aim of this study was to determine the effect of phenotypic RFI status and gender on the expression of key candidate genes related to processes involved in energy metabolism within AT.Dry matter intake(DMI) and average daily gain(ADG) were measured over a period of 70 d for 52 purebred Simmental heifers(n = 24) and bulls(n = 28) with an initial BW±SD of 372±39.6 kg and 387±50.6 kg,respectively.Residual feed intake was calculated and animals were ranked within gender by RFI into high(inefficient; n = 9 heifers and n = 8 bulls)and low(efficient; n = 9 heifers and n = 8 bulls) groups.Results: Average daily gain ±SD and daily DMI ±SD for heifers and bul s were 1.2±0.4 kg and 9.1±0.5 kg,and 1.8±0.3 kg and 9.5±1 kg respectively.High RFI heifers and bulls consumed 10% and 15% more(P < 0.05) than their low RFI counterparts,respectively.Heifers had a higher expression of all genes measured than bulls(P < 0.05).A gender × RFI interaction was detected for HMGCS2(P < 0.05) in which high RFI bulls tended to have lower expression of HMGCS2 than low RFI bulls(P < 0.1),whereas high RFI heifers had higher expression than low RFI heifers(P < 0.05) and high RFI bulls(P < 0.05).SLC2 A4 expression was consistently higher in subcutaneous AT of low RFI animals across gender.Conclusion: The findings of this study indicate that low RFI cattle exhibit upregulation of the molecular mechanisms governing glucose metabolism in adipose tissue,in particular,glucose clearance.The decreased expression of SLC2 A4 in the inefficient cattle may result in less efficient glucose metabolism in these animals.We conclude that SLC2 A4 may be a potential biomarker for RFI in cattle. | Clare McKenna Richard K.Porter Kate A.Keogh Sinead M.Waters Mark McGee David A.Kenny | 2019 | Journal of Animal Science and Biotechnology2019，10，1： | 2 |
| 15 | Tracking Groups of People显示文摘 | Stephen J. McKenna Sumer Jabri Zoran Duric Azriel Rosenfeld Harry Wechsler | 2000 | Computer Vision and Image Understanding2000，，1： | 2 |
| 16 | Video-assisted thoracic surgery versus open lobectomy for lung cancer: A secondary analysis of data from the American College of Surgeons Oncology Group Z0030 randomized clinical trial显示文摘 | Walter J. Scott Mark S. Allen Gail Darling Bryan Meyers Paul A. Decker Joe B. Putnam Robert W. Mckenna Rodney J. Landrenau David R. Jones Richard I. Inculet Richard A. Malthaner | 2010 | The Journal of Thoracic and Cardiovascular Surgery2010，，4： | 2 |
| 17 | Regional landslide-hazard assessment for Seattle, Washington, USA显示文摘 | Rex L. Baum Jeffery A. Coe Jonathan W. Godt Edwin L. Harp Mark E. Reid William Z. Savage William H. Schulz Dianne L. Brien Alan F. Chleborad Jonathan P. McKenna John A. Michael | 2005 | Landslides2005，，4： | 2 |
| 18 | Some remarks on a singular elliptic boundary value problem显示文摘 | Choi Y S Lazer A C McKenna P J | 1998 | Nonlinear Analysis Theory Methods and Applications1998，32，3： | 2 |
| 19 | Widespread genetic heterogeneity in multiple myeloma: implications for targeted therapy显示文摘 | Jens G. Lohr Petar Stojanov Scott L. Carter Peter Cruz-Gordillo Michael S. Lawrence Daniel Auclair Carrie Sougnez Birgit Knoechel Joshua Gould Gordon Saksena Kristian Cibulskis Aaron McKenna Michael A. Chapman Ravid Straussman Joan Levy Louise M. Perkins | 2013 | Cancer Cell2013，，： | 2 |
| 20 | Report of the 1995 World Health Organization/International Society and Federation of Cardiology Task Force on the Definition and Classification of Cardiomyopathies显示文摘 | P. : Richardson W. Rapporteur: McKenna M. Committee: Bristow B. Maisch B. Mautner J. O'Connell E. Olsen G. Thiene J. Consultant: Goodwin I. WHO Staff: Gyarfas I. Martin P. Nordet | 1996 | Circulation1996，，5： | 2 |
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