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| 1 | Feasibility study of computed vs measured high b-value(1400 s/mm2) diffusion-weighted MR images of the prostate显示文摘AIM: To evaluate the impact of computed b = 1400 s/mm2(C-b1400) vs measured b = 1400 s/mm2(M-b1400) diffusion-weighted images(DWI) on lesion detection rate, image quality and quality of lesion demarcation using a modern 3T-MR system based on a small-field-of-view sequence(sFOV). METHODS: Thirty patients(PSA: 9.5 ± 8.7 ng/mL; 68 ± 12 years) referred for magnetic resonance imaging(MRI) of the prostate were enrolled in this study. All measurements were performed on a 3T MR system.For DWI, a single-shot EPI diffusion sequence(b = 0, 100, 400, 800 s/mm2) was utilized. C-b1400 was cal-culated voxelwise from the ADC and diffusion images. Additionally, M-b1400 was acquired for evaluation and comparison. Lesion detection rate and maximum lesion diameters were obtained and compared. Image quality and quality of lesion demarcation were rated accord-ing to a 5-point Likert-type scale. Ratios of lesion-to-bladder as well as prostate-to-bladder signal intensity(SI) were calculated to estimate the signal-to-noise-ratio(SNR). RESULTS: Twenty-four lesions were detected on M-b1400 images and compared to C-b1400 images. C-b1400 detected three additional cancer suspicious lesions. Overall image quality was rated significantly better and SI ratios were significantly higher on C-b1400(2.3 ± 0.8 vs 3.1 ± 1.0, P < 0.001; 5.6 ± 1.8 vs 2.8 ± 0.9, P < 0.001). Comparison of lesion size showed no significant differences between C- and M-b1400(P = 0.22). CONCLUSION: Combination of a high b-value extrap-olation and sFOV may contribute to increase diagnostic accuracy of DWI without an increase of acquisition time, which may be useful to guide targeted prostate biopsies and to improve quality of multiparametric MRI(mMRI) especially under economical aspects in a pri-vate practice setting. | Leonardo K Bittencourt Ulrike I Attenberger Daniel Lima Ralph Strecker Andre de Oliveira Stefan O Schoenberg Emerson L Gasparetto Daniel Hausmann | 2014 | World Journal of Radiology2014，6，6： | 5 |
| 2 | 中国:如何维持平衡的增长显示文摘 | Richard Hausmann Michael Lipton 楼继伟 余永定 | 2006 | 国际经济评论2006，，4： | 4 |
| 3 | What you export matters显示文摘 | Ricardo Hausmann Jason Hwang Dani Rodrik | 2007 | Journal of Economic Growth2007，，1： | 4 |
| 4 | Role of soluble factors and three-dimensional culture in in vitro differentiation of intestinal macrophages显示文摘AIM: To examine the factor(s) involved in differentiation of intestinal macrophages (IMACs) using a recently established in vitro model. METHODS: To test whether soluble or membrane bound factors induce IMAC-differentiation, freshly elutriated monocytes (MO) were incubated with conditioned media or cell membranes of intestinal epithelial cells (IEC) or cultured with IEC in transwell systems. To determine the importance of an active migration of MO, three- dimensional aggregates from a 1:1-mixture of MO and IEC were examined by immunohistochemistry and flow cytometry. Apoptosis was examined by caspase-3 Western blots. Extracellular matrix production in differentiation models was compared by immunohistochemistry. RESULTS: IMAC differentiation was observed in a complex three-dimensional co-culture model (multicellular spheroid, MCS) with IEC after migration of MO into the spheroids. By co-culture of MO with conditioned media or membrane preparations of IEC no IMAC differentiation was induced. Co-culture of MO with IEC in transwell- cultures, with the two cell populations separated by a membrane also did not result in intestinal-like differentiation of MO. In contrast to IEC-spheroids with immigrating MO in mixed MCS of IEC and MO only a small subpopulation of MO was able to survive the seven day culture period. CONCLUSION: Intestinal-like differentiation of MO in vitro is only induced in the complex three-dimensional MCS model after immigration of MO indicating a roleof cell-matrix and/or cell-cell interactions during the differentiation of IMACs. | Tanja Spoettl Martin Hausmann Katrin Menzel Heidi Piberger Hans Herfarth Juergen Schoelmerich Frauke Bataille Gerhard Rogler | 2007 | World Journal of Gastroenterology2007，13，7： | 3 |
| 5 | Course ol glial immunoreactivity for vimentin,tenascin and alphal-antichymotrypsin after traumatic injury to human brain显示文摘 | Hausmann R Betz P | 2001 | Int J Legal Med2001，114，6： | 1 |
| 6 | Synthesis of 7- hydroxycoumarins by Pechmann reaction using Nafion resin/ silica nanocomposites as catalysts显示文摘 | Laufer M C Hausmann H Holderich W F | 2003 | Journal of Catalysis2003，218，2： | 1 |
| 7 | Downregulation of STAT3 signaling induces apoptosis but also promotes anti-apoptotic gene expression in human pancreatic cancer cell lines显示文摘 | Glienke W Hausmann E Bergmann L | 2011 | Tumour Biol2011，32，3： | 1 |
| 8 | Endoluminal Endosurgery:Rivet Application in Flexible Endoscopy显示文摘 | Hausmann U Feussner H Ahrens P | 2006 | Gastrointest Endosc2006，64，1： | 1 |
| 9 | Toll like receptors 2 and 4 are upregulated during intestinal inflammation 显示文摘 | Hausmann M Kiessling S Mestermann S | 2002 | Gastroenterology2002，122，： | 1 |
| 10 | Impact of lalI -SPECT/CT images obtained with an integrat- ed system in the follow-up of patients with thyroid carcinoma 显示文摘 | Tharp K Israel O Hausmann J | 2004 | Eur J Nucl Med Mol Imaging2004，31，10： | 1 |
| 11 | Post-traumatic inflammation following spinal cord injury 显示文摘 | Hausmann O N | | Spinal Cord0，41，7： | 1 |
| 12 | CpG oligodeoxynucleotides trigger protective and curative Th1 responses in lethal murine leishmaniasis显示文摘 | Hausmann S Lipford GB | 1998 | Immunol1998，160，： | 1 |
| 13 | Organophilic pervaporation:prospects and performance显示文摘 | Frank Lipnizki Stephan Hausmanns | 1999 | Chemical Engineering Journal1999，73，： | 1 |
| 14 | Pro-apoptotic apoptosis protease-activating factor 1 (Apaf-1) has a cytoplasmic localization distinct from Bcl-2 or Bcl-x(L) 显示文摘 | Hausmann G O'Reilly LA van Driel R | 2000 | J Cell Biol2000，149，： | 1 |
| 15 | The association between osteoporosis and alveolar crestal height in postmenopausal women显示文摘 | Wactawski WJ Hausmann E Hovey K | 2005 | J Periodontol2005，76，11： | 1 |
| 16 | Currency mismatches,exchange rate policy显示文摘 | Eichengreen B Hausmann R U Panizza | 2003 | American Economic Review2003a2003，94，4： | 1 |
| 17 | Chronic Repetitive Transcranial Magnetic Stimulation Enhances C-fos in the Parietal Cortex and Hippocampus显示文摘 | HAUSMANN A WEIS C MARKSTEINER J | 2000 | Brain Res Mol Brain Res(S0169-328X)2000，76，2： | 1 |
| 18 | A Supported Employment Experience in Western Switzerland for Persons with Mental Health Disorders显示文摘 | Dutoit M Besse C Hausmann P | 2014 | Rev Med Suisse2014，10，442： | 1 |
| 19 | Heteromeric assembly of P2X subunits显示文摘 | Saul A Hausmann R Kless A | 2013 | Front Cell Neurosci2013，7，2： | 1 |
| 20 | Is foreign direct invesllnent a safer form of financing显示文摘 | HAUSMANN R FERNANDEZ E | 2001 | Emerging Markets Review2001，，2： | 1 |
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