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| 1 | Management of patients after recovering from acute severe biliary pancreatitis显示文摘Cholelithiasis is the most common cause of acute pancreatitis,accounting 35%-60% of cases. Around 15%-20% of patients suffer a severe attack with high morbidity and mortality rates. As far as treatment is concerned,the optimum method of late management of patients with severe acute biliary pancreatitis is still contentious and the main question is over the correct timing of every intervention. Patients after recovering from an acute episode of severe biliary pancreatitis can be offered alternative options in their management,including cholecystectomy,endoscopic retrograde cholangiopancreatography(ERCP) and sphincterotomy,or no definitive treatment. Delaying cholecystectomy until after resolution of the inflammatory process,usually not earlier than 6 wk after onset of acute pancreatitis,seems to be a safe policy. ERCP and sphincterotomy on index admission prevent recurrent episodes of pancreatitis until cholecystectomy is performed,but if used for definitive treatment,they can be a valuable tool for patients unfit for surgery. Some patients who survive severe biliary pancreatitis may develop pseudocysts or walled-off necrosis. Management of pseudocysts with minimally invasive techniques,if not therapeutic,can be used as a bridge to definitive operative treatment,which includes delayed cholecystectomy and concurrent pseudocyst drainage in some patients. A management algorithm has been developed for patients surviving severe biliary pancreatitis according to the currently published data in the literature. | Georgia Dedemadi Manolis Nikolopoulos Ioannis Kalaitzopoulos George Sgourakis | 2016 | World Journal of Gastroenterology2016，22，34： | 20 |
| 2 | Arsenic speciation in fish from Greek coastal areas显示文摘Arsenic speciation analysis was conducted on fish samples(sardine and anchovy) collected from six areas along the Greek coastline, i.e. Artemisium Straits, Thermaikos Gulf, Amvrakikos Gulf,Strymonian Gulf, Thracian Sea, and Elefsina Gulf. Total arsenic levels ranging from 11.8 to62.6 mg As/kg dry weight were determined. Arsenobetaine, a non-toxic form of arsenic, was found to be the main arsenic species, present at 8.6 to 58.8 mg As/kg dry weight, accounting for67–95% of the total arsenic. Also detected in all fish samples was dimethylarsinic acid, although at considerably lower concentrations, ranging from 0.072–0.956 mg As/kg dry weight.Monomethylarsonic acid was detected at low levels in all anchovy samples, and only in sardines from one area. Finally, inorganic arsenic in the form of arsenate was detected only in fish at one area, indicating the possible effect of an environmental parameter on its presence at detectable amounts. Statistical analysis revealed the environmental variables, such as salinity,total organic carbon and nitrogen, ammonium, phosphate, total phosphorus, dissolved oxygen and pressure index, are potentially correlated to As species concentrations. Furthermore, based on factor analysis, the biological parameters, such as fish weight, lipids, protein and ash content,that are correlated to As species concentrations of fish were also identified. The interrelationship of arsenobetaine and dimethylarsinic acid concentrations within each fish species was evaluated. | Ioanna Kalantzi Kyriaki Mylona Katerina Sofoulaki Manolis Tsapakis Spiros A.Pergantis | 2017 | Journal of Environmental Sciences2017，29，6： | 11 |
| 3 | 两段式低温真空烹饪对牛肉品质的影响显示文摘真空低温烹饪具有改善肉类品质、减少营养素损失和延长保质期等优势,然而该技术能否替代传统煎制牛排还未见报道。该文通过对牛排的烹饪损失、剪切力、色泽、挥发性风味物质以及电子鼻的风味分析,对比了传统煎制与两段式真空低温烹饪牛肉的品质。结果表明,经两段式真空低温烹饪的牛肉在烹饪损失、剪切力和红度等方面均优于传统煎制牛排,而传统油煎牛排亮度较好。传统煎制牛肉有43种挥发性风味物质,真空低温烹饪后油煎的牛肉有28种,油煎后真空低温烹饪牛肉有37种。经电子鼻分析,3种烹饪方式的牛肉中2种真空低温烹饪方式的牛肉风味接近,但与传统油煎牛肉风味有差异。该研究可为牛排工业化生产提供参考。 | 闫寒 崔震昆 李阳阳 MANOLI Tatiana 赵岩岩 周威 张浩 李岚轩 | 2021 | 食品与发酵工业2021，47，18： | 11 |
| 4 | Identification of Oxidative Stress and Toll-like Receptor 4 Signaling as a Key Pathway of Acute Lung Injury显示文摘 | Yumiko Imai Keiji Kuba G. Greg Neely Rubina Yaghubian-Malhami Thomas Perkmann Geert van Loo Maria Ermolaeva Ruud Veldhuizen Y.H. Connie Leung Hongliang Wang Haolin Liu Yang Sun Manolis Pasparakis Manfred Kopf Christin Mech Sina Bavari J.S. Malik Peiris Ar | 2008 | Cell2008，，2： | 4 |
| 5 | Differences in inflammatory and thrombotic markers between unstable angina and acute myocardial infarction显示文摘 | Dimitris Tousoulis Charalambos Antoniades Erini Bosinakou Maria Kotsopoulou Costas Tsoufis Kyriakoula Marinou Marietta Charakida Elli Stefanadi Manolis Vavuranakis George Latsios Christodoulos Stefanadis | 2006 | International Journal of Cardiology2006，，2： | 2 |
| 6 | 评估饮用水中化学物暴露与健康结局:认识和研究需求现状显示文摘[背景]安全的饮用水对于健康至关重要。虽然在全球范围内,微生物污染仍然是饮用水相关疾病发病率和死亡率的最主要原因,但在供水中的化学物也可能导致疾病,而其中一些的人体健康结局的证据有限或缺乏。[目的]旨在总结当前人们对这一问题的了解状况,找出认识差距,并为与饮用水中化学物相关的流行病学研究提供建议。[讨论]评估饮用水中化学物暴露与健康结局十分具有挑战性。暴露通常为低浓度,在水中测量是通常是不够的,化学物以混合物形式存在,暴露时间通常很长,可能涉及多个暴露途径,而能够反映相应暴露阶段的有效生物标志却很少。此外,相对风险的幅度具有变小趋势。[结论]研究应该包括:设计良好的流行病学研究,涵盖能够比较污染程度并具有足够样本量的地区;结合生物分析并整合复杂混合物影响的污染物产生综合评价;足够水中测量次数,以评估地理和时间变异性;有关导致暴露的个人生活习惯的详细信息(例如,摄入、淋浴、游泳和饮食);生物样本的采集,以测量相关的生物标志;先进的统计模型,以评估暴露和相对风险,并应考虑解决测量误差的方法。最后,纳入早期生物效应和遗传易感性的分子标志对于了解化学物作用机制是必不可少的。需要评估大量新出现的污染物的风险和人类暴露,但这些知识仍然缺乏。 | Cristina M.Villanueva Manolis Kogevinas Sylvaine Cordier Michael R.Templeton Roel Vermeulen John R.Nuckols Mark J.Nieuwenhuijsen Patrick Levallois 汪源 张伊人 何蓉 金泰廙 | 2014 | 环境与职业医学2014，31，8： | 2 |
| 7 | Source Apportionment of Urban Particulate Aliphatic and Polynuclear Aromatic Hydrocarbons(PAHs) Using Multivariate Methods 显示文摘 | Ilias G K Petros K Manolis T | 2001 | Environmental Science & Technology2001，35，： | 2 |
| 8 | Bioconcentration of polycyclic aromatic hydrocarbons in vegetables grown in an industrial area显示文摘 | A.M. Kipopoulou E. Manoli C. Samara | 1999 | Environmental Pollution1999，，3： | 2 |
| 9 | Endothelial Cell-Specific NF-κB Inhibition Protects Mice from Atherosclerosis显示文摘 | Ralph Gareus Elena Kotsaki Sofia Xanthoulea Ingeborg van der Made Marion J.J. Gijbels Rozina Kardakaris Apostolos Polykratis George Kollias Menno P.J. de Winther Manolis Pasparakis | 2008 | Cell Metabolism2008，，5： | 2 |
| 10 | Ileal Malignant Melanoma Causing Intussusception: Report of a Case显示文摘 | Konstantinos Karmiris Maria Roussomoustakaki Maria Tzardi John Romanos John Grammatikakis Manolis Papadakis Maria Polychronaki Elias A. Kouroumalis | 2007 | Surgery Today2007，，6： | 2 |
| 11 | Intelligent Controls显示文摘 | Manolis Christodoulon | 1995 | Journal of Intelligent and Robotic Systems1995，，12： | 1 |
| 12 | Relationship quality and buyer-seller interactions in channels of distribution显示文摘 | Jap S D Manolis C Weitz B A | 1999 | Journal of Business Research1999，46，3： | 1 |
| 13 | New catalysts fordeep hydrotreatment of diesel fuel: Kinetics of 4,6-dimethyldibenzothiophenehydrodesulfurization over aluminasupportedmolybdenum carbide显示文摘 | Costa P Da Potvin C Manoli J M | 2002 | Journal of MolecularCatalysis A: Chemistry2002，184，12： | 1 |
| 14 | Pathoanatomy and etiology of posterior tibial tendon dysfunction显示文摘 | Mosier SM Pomeroy G Manoli A | 1999 | Clin Orthop1999，365，： | 1 |
| 15 | Inducing Z-DNA overcomes immune checkpoint blockade resistance显示文摘Inducing immunogenic cell death in tumors holds promise in stimulating anti-tumor immunity.A recent study published in Nature reported that a small molecule previously shown to induce the formation of Z-DNA activates ZBP1-dependent cell death and renders tumors sensitive to immune checkpoint blockade-based immunotherapy.Cancer immunotherapy by immune checkpoint blockade(ICB)has achieved remarkable success in individual cases;however,these are still restricted to a small number of patients.Therefore,novel approaches to enhance anti-tumor immunity are urgently needed.Induction of immunogenic cell death,such as necroptosis,in tumor cells was shown to synergize with ICB to induce antitumor immune responses in mouse models.1 The RNA-editing enzyme adenosine deaminase acting on RNA 1(ADAR1)has emerged as a novel checkpoint conferring resistance to ICB therapy. | Huipeng Jiao Manolis Pasparakis | 2022 | Cell Research2022，32，10： | 1 |
| 16 | Bioconcentration of polycyclic aromatic hydrocarbons in vegetables gown in an industrial area显示文摘 | KIPOPOULOU A M MANOLI E SAMARA C | 1999 | Environmental Pollution1999，106，3： | 1 |
| 17 | The effect of plantar fascia release on strain in the spring and long plantar ligaments 显示文摘 | Crary JL Hollis JM Manoli A | 2003 | Foot Ankle Int2003，24，： | 1 |
| 18 | 显示文摘 | Manoli F Dalas E | 2000 | J Crystal Growth2000，218，： | 1 |
| 19 | Risk analysis of industrial structure under extreme transient loads显示文摘 | Talaslidis D G Manolis G D | 2004 | Soil Dynamics and Earthquake Engineering2004，24，4： | 1 |
| 20 | The value of a new speckle tracking index including left ventricular global longitudinal strain and torsion in patients with dilated cardiomyopathy显示文摘 | Morno SC RuSinam D Manolis A J | 2011 | Hel- lenic J Cardiol2011，52，： | 1 |
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