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| 1 | Endoscopic ultrasonography findings in autoimmune pancreatitis显示文摘Endoscopic ultrasonography is an established diagnostic tool for pancreatic masses and chronic pancreatitis.In recent years there has been a growing interest in the worldwide medical community in autoimmune pancreatitis (AIP),a form of chronic pancreatitis caused by an autoimmune process.This paper reviews the current available literature about the endoscopic ultrasonographic findings of AIP and the role of this imaging technique in the management of this protean disease. | Elisabetta Buscarini Stefania De Lisi Paolo Giorgio Arcidiacono Maria Chiara Petrone Arnaldo Fuini Rita Conigliaro Guido Manfredi Raffaele Manta Dario Reggio Claudio De Angelis | 2011 | World Journal of Gastroenterology2011，17，16： | 6 |
| 2 | Role of endoscopic vacuum therapy in the management of gastrointestinal transmural defects显示文摘A gastrointestinal(GI) transmural defect is defined as total rupture of the GI wall,and these defects can be divided into three categories: perforations,leaks,and fistulas. Surgical management of these defects is usually challenging and may be associated with high morbidity and mortality rates. Recently,several novel endoscopic techniques have been developed,and endoscopy has become a firstline approach for therapy of these conditions. The use of endoscopic vacuum therapy(EVT) is increasing with favorable results. This technique involves endoscopic placement of a sponge connected to a nasogastric tube into the defect cavity or lumen. This promotes healing via five mechanisms,including macrodeformation,microdeformation,changes in perfusion,exudate control,and bacterial clearance,which is similar to the mechanisms in which skin wounds are treated with commonly employed wound vacuums. EVT can be used in the upper GI tract,small bowel,biliopancreatic regions,and lower GI tract,with variable success rates and a satisfactory safety profile. In this article,we review and discuss the mechanism of action,materials,techniques,efficacy,and safety of EVT in the management of patients with GI transmural defects. | Diogo Turiani Hourneaux de Moura Bruna Furia Buzetti Hourneaux de Moura Michael A Manfredi Kelly E Hathorn Ahmad N Bazarbashi Igor Braga Ribeiro Eduardo Guimaraes Hourneaux de Moura Christopher C Thompson | 2019 | World Journal of Gastrointestinal Endoscopy2019，11，5： | 6 |
| 3 | Laparoscopic management of intra-abdominal infections:Systematic review of the literature显示文摘AIM: To investigate the role of laparoscopy in diagnosis and treatment of intra abdominal infections.METHODS: A systematic review of the literature was performed including studies where intra abdominal infections were treated laparoscopically.RESULTS: Early laparoscopic approaches have become the standard surgical technique for treating acute cholecystitis. The laparoscopic appendectomy has been demonstrated to be superior to open surgery in acute appendicitis. In the event of diverticulitis, laparoscopic resections have proven to be safe and effective procedures for experienced laparoscopic surgeons and may be performed without adversely affecting morbidity and mortality rates. However laparoscopic resection has not been accepted by the medical community as the primary treatment of choice. In high-risk patients, laparoscopic approach may be used for exploration or peritoneal lavage and drainage. The successful laparoscopic repair of perforated peptic ulcers for experienced surgeons, is demonstrated to be safe and effective. Regarding small bowel perforations, comparative studies contrasting open and laparoscopic surgeries have not yet been conducted. Successful laparoscopic resections addressing iatrogenic colonic perforation have been reported despite a lack of literature-based evidence supporting such procedures. In post-operative infections, laparoscopic approaches may be useful in preventing diagnostic delay and controllingthe source.CONCLUSION: Laparoscopy has a good diagnostic accuracy and enables to better identify the causative pathology; laparoscopy may be recommended for the treatment of many intra-abdominal infections. | Federico Coccolini Cristian Tranà Massimo Sartelli Fausto Catena Salomone Di Saverio Roberto Manfredi Giulia Montori Marco Ceresoli Chiara Falcone Luca Ansaloni | 2015 | World Journal of Gastrointestinal Surgery2015，7，8： | 5 |
| 4 | Needle-based confocal endomicroscopy in the discrimination of mucinous from non-mucinous pancreatic cystic lesions显示文摘BACKGROUND Pancreatic cystic lesions(PCLs)are considered a precursor of pancreatic cancer.Needle-based confocal endomicroscopy(nCLE)is an imaging technique that enables visualization of the mucosal layer to a micron resolution.Its application has demonstrated promising results in the distinction of PCLs.This study evaluated the utility of nCLE in patients with indeterminate PCLs undergoing endoscopic ultrasound fine-needle aspiration(EUS-FNA)to distinguish mucinous from non-mucinous lesions.AIM To evaluate the accuracy of nCLE in indeterminate PCLs undergoing EUS-FNA to distinguish mucinous from non-mucinous lesions.METHODS Patients who required EUS-FNA between 2015 and 2017 were enrolled prospectively.During EUS-FNA,confocal imaging,analyses of the tumor markers carcinoembryonic antigen and amylase,and cytologic examination were conducted.All patients were followed for at least 12 mo and underwent laboratory testing and computed tomography scanning or magnetic resonance imaging.nCLE videos were independently reviewed by 6 observers to reach a final diagnosis(mucinous vs non-mucinous)based on criteria derived from previous studies;if there was disagreement>20%,a final diagnosis was discussed after consensus re-evaluation.The sensitivity,specificity,and accuracy of nCLE were calculated.Adverse events were recorded.RESULTS Fifty-nine patients were included in this study.Final diagnoses were derived from surgery in 10 patients,cytology in 13,and imaging and multidisciplinary team review in 36.Three patients were excluded from final diagnosis due to problems with nCLE acquisition.Fifty-six patients were included in the final analysis.The sensitivity,specificity,and accuracy of nCLE were 80%[95%confidence interval(CI):65-90],100%(95%CI:72-100),and 84%(95%CI:72-93),respectively.Postprocedure acute pancreatitis occurred in 5%.CONCLUSION EUS-nCLE performs better than standard EUS-FNA for the diagnosis of indeterminate PCL. | Helga Bertani Raffaele Pezzilli Flavia Pigo Mauro Bruno Claudio De Angelis Guido Manfredi Gabriele Delconte Rita Conigliaro Elisabetta Buscarini | 2021 | World Journal of Gastrointestinal Endoscopy2021，13，11： | 4 |
| 5 | Type I interferon-mediated pathway interacts with peroxisome proliferator activated receptor-γ (PPAR-γ): At the cross-road of pancreatic cancer cell proliferation显示文摘 | Alessandra Dicitore Michele Caraglia Germano Gaudenzi Gloria Manfredi Bruno Amato Daniela Mari Luca Persani Claudio Arra Giovanni Vitale | 2014 | BBA - Reviews on Cancer2014，，1： | 3 |
| 6 | Immune reaction and colorectal cancer:Friends or foes?显示文摘The potential clinical impact of enhancing antitumor immunity is increasingly recognized in oncology therapeutics for solid tumors.Colorectal cancer is one of the most studied neoplasms for the tumor-host immunity relationship.Although immune cell populations involved in such a relationship and their prognostic role in colorectal cancer development have clearly been identified,still no approved therapies based on host immunity intensification have so far been introduced in clinical practice.Moreover,a recognized risk in enhancing immune reaction for colitis-associated colorectal cancer development has limited the emphasis of this approach.The aim of the present review is to discuss immune components involved in the host immune reaction against colorectal cancer and analyze the fine balance between pro-tumoral and anti-tumoral effect of immunity in this model of disease. | Vincenzo Formica Vittore Cereda Antonella Nardecchia Manfredi Tesauro Mario Roselli | 2014 | World Journal of Gastroenterology2014，20，35： | 3 |
| 7 | European experts consensus statement on cystic tumours of the pancreas显示文摘 | Marco Del Chiaro Caroline Verbeke Roberto Salvia Gunter Kl?ppel Jens Werner Colin McKay Helmut Friess Riccardo Manfredi Eric Van Cutsem Matthias L?hr Ralf Segersv?rd | 2013 | Digestive and Liver Disease2013，，： | 3 |
| 8 | Small bowel adenocarcinoma: Epidemiology, risk factors, diagnosis and treatment显示文摘 | Thomas Aparicio Aziz Zaanan Magali Svrcek Pierre Laurent-Puig Nicolas Carrere Sylvain Manfredi Christophe Locher Pauline Afchain | 2014 | Digestive and Liver Disease2014，，2： | 3 |
| 9 | Epidemiology and Management of Liver Metastases From Colorectal Cancer显示文摘 | Sylvain Manfredi C?me Lepage Cyril Hatem Olivier Coatmeur Jean Faivre Anne-Marie Bouvier | 2006 | Annals of Surgery2006，，2： | 2 |
| 10 | Peripheral CD45RO, PD-1, and TLR4 expression in metastatic colorectal cancer patients treated with bevacizumab, fluorouracil, and irinotecan (FOLFIRI-B)显示文摘 | Vincenzo Formica Vittore Cereda Maria-Giovana Bari Italia Grenga Manfredi Tesauro Palmirotta Raffaele Patrizia Ferroni Fiorella Guadagni Mario Roselli | 2013 | Medical Oncology2013，，4： | 2 |
| 11 | Review in depth and meta-analysis of controlled trials on colorectal cancer screening by faecal occult blood test显示文摘 | Denis Heresbach Sylvain Manfredi Pierre N. D?Halluin Jean-Fran?ois Bretagne Bernard Branger | 2006 | European Journal of Gastroenterology & Hepatology2006，，4： | 2 |
| 12 | Magnetic Resonance Imaging of Cholangiocarcinoma显示文摘 | Riccardo Manfredi Brunella Barbaro Gabriele Masselli Amorino Vecchioli Pasquale Marano | 2004 | Semin Liver Dis2004，，02： | 2 |
| 13 | Helicobacter pylori Infection in Clinical Practice: Probiotics and a Combination of Probiotics?+?Lactoferrin Improve Compliance, But Not Eradication, in Sequential Therapy显示文摘 | Marco Manfredi Barbara Bizzarri Roberto Igino Sacchero Sergio Maccari Lorenzo Calabrese Fabio Fabbian Gian Luigi de’Angelis | 2012 | Helicobacter2012，，4： | 2 |
| 14 | Diagnostic efficacy of gadoxetic acid (Primovist)-enhanced MRI and spiral CT for a therapeutic strategy: comparison with intraoperative and histopathologic findings in focal liver lesions显示文摘 | Renate Hammerstingl Alexander Huppertz Josy Breuer Thomas Balzer Anthony Blakeborough Rick Carter Lluis Castells Fusté Gertraud Heinz-Peer Werner Judmaier Michael Laniado Riccardo M. Manfredi Didier G. Mathieu Dieter Müller Koenraad Mortelè Peter Reimer M | 2008 | European Radiology2008，，： | 2 |
| 15 | Helicobacter pylori Infection: Sequential Therapy Followed by Levofloxacin‐Containing Triple Therapy provides a Good Cumulative Eradication Rate显示文摘 | Marco Manfredi Barbara Bizzarri Gian Luigi de’Angelis | 2012 | Helicobacter2012，，4： | 2 |
| 16 | Non-linear modeling of RC rectangular hollow piers confined with CFRP显示文摘 | G.P. Lignola A. Prota G. Manfredi E. Cosenza | 2008 | Composite Structures2008，，1： | 2 |
| 17 | Helicobacter pylori Infection in Clinical Practice: Probiotics and a Combination of Probiotics?+?Lactoferrin Improve Compliance, But Not Eradication, in Sequential Therapy显示文摘 | Marco Manfredi Barbara Bizzarri Roberto Igino Sacchero Sergio Maccari Lorenzo Calabrese Fabio Fabbian Gian Luigi de’Angelis | 2012 | Helicobacter2012，，4： | 2 |
| 18 | Measurements of ATP in mammalian cells显示文摘 | Manfredi G Yang L Gajewski C D | 2002 | Methods2002，26，： | 1 |
| 19 | The ineidenee of venous thromboembolism following gynecologic laparoscopy:a multicenter,prospective cehoa study显示文摘 | Manfredi E Dentali F | 2007 | J Thromb Haernost2007，5，3： | 1 |
| 20 | The use of damage functionals in earthquake engineering:A comparision between different methods显示文摘 | Coseza E Manfredi G Ramasco R | 1993 | Earthquake Engineering and Structural Dynamics1993，22，： | 1 |
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