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| 1 | Renin-angiotensin system in the kidney: What is new?显示文摘The renin-angiotensin system(RAS)has been known for more than a century as a cascade that regulates body fluid balance and blood pressure.AngiotensinⅡ(AngⅡ)has many functions in different tissues;however it is on the kidney that this peptide exerts its main functions.New enzymes,alternative routes for AngⅡformation or even active AngⅡ-derived peptides have now been described acting on AngⅡAT1or AT2receptors,or in receptors which have recently been cloned,such as Mas and AT4.Another interesting observation was that old members of the RAS,such as angiotensin converting enzyme(ACE),renin and prorenin,well known by its enzymatic activity,can also activate intracellular signaling pathways,acting as an outside-in signal transduction molecule or on the renin/(Pro)renin receptor.Moreover,the endocrine RAS,now is also known to have paracrine,autocrine and intracrine action ondifferent tissues,expressing necessary components for local AngⅡformation.This in situ formation,especially in the kidney,increases AngⅡlevels to regulate blood pressure and renal functions.These discoveries,such as the ACE2/Ang-(1-7)/Mas axis and its antangonistic effect rather than classical deleterious AngⅡeffects,improves the development of new drugs for treating hypertension and cardiovascular diseases. | Fernanda M Ferr?o Lucienne S Lara Jennifer Lowe | 2014 | World Journal of Nephrology2014，3，3： | 5 |
| 2 | The sodium-activated sodium channel is expressed in the rat kidney thick ascending limb and collecting duct cells and is upregulated during high salt intake显示文摘 | Lucienne S. Lara Ryousuke Satou Camille R. T. Bourgeois Alexis A. Gonzalez Andrea Zsombok Minolfa C. Prieto L. Gabriel Navar | 2012 | AJP: Renal Physiology2012，，1： | 1 |
| 3 | Tolerance to islet autoantigens in type 1diabetes显示文摘 | Jean-Francois Bach and Lucienne Chatenoud | 2001 | Annu Rev Immunol2001，19，： | 1 |
| 4 | 12-Month Follow-up After Successful Infliximab Therapy in Pediatric Crohn Disease显示文摘 | Jan Wynands Reda Belbouab Sophie Candon Cécile Talbotec Jean-Fran?ois Mougenot Lucienne Chatenoud Jacques Schmitz Jean-Pierre Cézard Olivier Goulet Jean-Pierre Hugot Frank M Ruemmele | 2008 | Journal of Pediatric Gastroenterology and Nutrition2008，，3： | 1 |
| 5 | BMI1 , The polycomb‐group gene, is recurrently targeted by genomic rearrangements in progressive B‐cell leukemia/lymphoma显示文摘 | Leila Rouhigharabaei Julio Finalet Ferreiro Natalie Put Lucienne Michaux Thomas Tousseyn Christine Lefebvre Anne Gardiner Wim Kelver Hilde Demuynck Johan Verschuere Ivan Théate Carmen Vicente Peter Vandenberghe Jan Cools Iwona Wlodarska | 2013 | Genes Chromosomes Cancer2013，，10： | 1 |
| 6 | A historical view from thirty eventful years of immunotherapy in autoimmune diabetes显示文摘 | Jean-Franois Bach Lucienne Cbatenoud | 2011 | Semin Immunol2011，23，3： | 1 |
| 7 | Clinical and biological consequences of immunization to infliximab in pediatric Crohn’s disease显示文摘 | Sophie Candon Alexis Mosca Frank Ruemmele Olivier Goulet Lucienne Chatenoud Jean-Pierre Cézard | 2005 | Clinical Immunology2005，，1： | 1 |
| 8 | Intergenerational Class Mobility and the Convergence Thesis:England,France and Sweden显示文摘 | Erikson Robert John H.Goldthorpe Lucienne Portocarero | | 0，，34： | 1 |
| 9 | ZnT8 Is a Major CD8+ T Cell–Recognized Autoantigen in Pediatric Type 1 Diabetes显示文摘 | émmanuelle énée Roland Kratzer Jean-Baptiste Arnoux Emilie Barilleau Yamina Hamel Christophe Marchi Jacques Beltrand Bénédicte Michaud Lucienne Chatenoud Jean-Jacques Robert Peter van Endert | 2012 | Diabetes2012，，7： | 1 |
| 10 | Adaptive human regulatory T cells: myth or reality显示文摘 | LUCIENNE C JEAN-FRANOIS B | 2006 | J Clin Invest2006，116，9： | 1 |
| 11 | Efficacy of an experimentally inactivated Streptococcus agalactiae vaccine in Nile tilapia (Oreochromis niloticus) reared in Brazil显示文摘 | Lucienne GarciaPretto‐Giordano Ernst EckehardtMüller PhillipKlesius Vanessa GomesDa Silva | 2009 | Aquaculture Research2009，，10： | 1 |
| 12 | Mammo- sphere culture of metastatic breast cancer cells enriches for tu- modgenic breast cancer ceils 显示文摘 | Matthew J G Lucienne C Konstantinos P | 2008 | Breast Cancer Res2008，10，3： | 1 |
| 13 | microRNA-29c and microRNA-223 down-regulation has in vivo significance in chronic lymphocytic leukemia and improves disease risk stratification显示文摘 | Lagneaux N Lucienne M Pierre H | 2009 | {H}Blood2009，，21： | 1 |
| 14 | Evaluation on the pathogenesis of Streptococcus agalactiae in Nile tilapia (Oreochromis niloticus) 显示文摘 | LUCIENNE G P ERNST E M PHILLIP K | 2010 | Braz Arch Biol Technol2010，53，1： | 1 |
| 15 | The targeted delivery of cancer drugs across the blood-brain barrier:chemical modifications of drugs or drug- nanoparticales显示文摘 | Lucienne J | 2008 | Drug Discovery Today2008，13，2324： | 1 |
| 16 | The influence of corticosteroids on the release of novel biomarkers in human endotoxemia显示文摘 | Martijn D. Kruif Lucienne C. Lemaire Ida A. Giebelen Joachim Struck Nils G. Morgenthaler Jana Papassotiriou Peter J. Elliott Tom Poll | 2008 | Intensive Care Medicine2008，，3： | 1 |
| 17 | Evaluation of the bioremoval of Cr(VI) and TOC in biofilters under continuous operation using response surface methodology显示文摘 | Daniela Leles Diego Lemos Ubirajara Filho Lucienne Romanielo Miriam Resende Vicelma Cardoso | 2012 | Biodegradation2012，，3： | 1 |
| 18 | Engineering alginate for intervertebral disc repair显示文摘 | Johannes L. Bron Lucienne A. Vonk Theodoor H. Smit Gijsje H. Koenderink | 2011 | Journal of the Mechanical Behavior of Biomedical Materials2011，，7： | 1 |
| 19 | Dipeptidyl peptidase IV and its inhibitors: Therapeutics for type 2 diabetes and what else?显示文摘 | Lucienne J J | 2014 | J Med Chem2014，57，： | 1 |
| 20 | Determinants of angiotensin II generation during converting enzyme inhibition 显示文摘 | Lucienne J Jnrg N Joel M | 1990 | Hypertension1990，16，5： | 1 |
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