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| 1 | Stronger inhibition of gastric acid secretion by lafutidine, a novel H_2 receptor antagonist, than by the proton pump inhibitor lansoprazole显示文摘AIM: To compare the antisecretory activity and plasma drug concentrations of a single oral dose of 10 mg lafutidine, a novel H2 receptor antagonist, with those of the proton pump inhibitor lansoprazole (LPZ) 30 mg. METHODS: Ten volunteers without H pylori infection participated in this crossover study comparing lafutidine 10 mg with LPZ 30 mg. Intragastric pH was monitored for 6 h in all participants, and blood samples were collected from four randomly selected individuals after single-dose administration of each drug. RESULTS: The median intragastric pH was significantly higher in individuals who received lafutidine 10 mg than in those who received LPZ 30 mg 2, 3, 4, 5, and 6 h after administration. Maximal plasma drug concentration was reached more promptly with lafutidine 10 mg than with LPZ 30 mg. CONCLUSION: In H pylori-negative individuals, gastric acid secretion is more markedly inhibited by lafutidinethan by LPZ. | Hatsushi Yamagishi Tomoyuki Koike Shuichi Ohara Toru Horii Ryousuke Kikuchi Shigeyuki Kobayashi Yasuhiko Abe Katsunori Iijima Akira Imatani Kaori Suzuki Takanori Hishinuma Junichi Goto Tooru Shimosegawa | 2008 | World Journal of Gastroenterology2008，14，15： | 3 |
| 2 | Early effects of Lansoprazole orally disintegrating tablets on intragastric pH in CYP2C19 extensive metabolizers显示文摘AIM: To compare rabeprazole (RPZ; 10 mg) with Lansoprazole orally disintegrating tablets (LPZ; 30 mg OD) in terms of antisecretory activity and blood drug concentration after a single dose. METHODS: Eight H pylori-negative cytochrome P450 (CYP) 2C19 extensive metabolizers were assigned to receive a single oral dose of RPZ 10 mg or LPZ 30 mg OD. Twelve hour intragastric pH monitoring was perform- ed on the day of treatment. Blood samples were also collected after the administration of each drug. RESULTS: LPZ 30 mg OD induced a significantly earlier rise in blood drug concentration than RPZ 10 mg; consequently, LPZ 30 mg OD induced a significantly earlier rise in median pH in the third and fourth hours of the study. CONCLUSION: In H pylori-negative CYP2C19 extensive metabolizers, LPZ 30 mg OD induced a significantly faster inhibition of gastric acid secretion than RPZ 10 mg. | Hatsushi Yamagishi Tomoyuki Koike Shuichi Ohara Toru Horii Ryousuke Kikuchi Shigeyuki Kobayashi Yasuhiko Abe Katsunori Iijima Akira Imatani Kaori Suzuki Takanori Hishinuma Junichi Goto Tooru Shimosegawa | 2008 | World Journal of Gastroenterology2008，14，13： | 2 |
| 3 | Automatic Analysis of Normal Bone Marrow Blood Cells Using the XE-2100 Automated Hematology Analyzer显示文摘 | Hisako Shibata Takahisa Yamane Ryousuke Yamamura | 2003 | Journal of Clinical Laboratory Analysis2003，，17： | 1 |
| 4 | Etching mechanism of polyimide film with nitrogen trifluoride/ oxygen gas plasma显示文摘 | SATORU I RYOUSUKE N NORIYUKI Y | 2000 | Shinku/Journal of the Vacuum Society of Japan2000，43，4： | 1 |
| 5 | Ginseng enhances contextual fear conditioning and neurogenesis in rats显示文摘 | Chunxiang Qiao Ryousuke D Koutaro K | 2005 | Neuroscience R2005，51，： | 1 |
| 6 | Ginseng enhances contextual fear conditioning and neurogenesis in rats显示文摘 | Chunxiang Qiao Ryousuke D Koutaro K | 2005 | Neuroscience R2005，51，： | 1 |
| 7 | The sodium-activated sodium channel is expressed in the rat kidney thick ascending limb and collecting duct cells and is upregulated during high salt intake显示文摘 | Lucienne S. Lara Ryousuke Satou Camille R. T. Bourgeois Alexis A. Gonzalez Andrea Zsombok Minolfa C. Prieto L. Gabriel Navar | 2012 | AJP: Renal Physiology2012，，1： | 1 |
| 8 | A consideration of potentials of low-density polyethylene using metallocene catalyst as insulator for power cable显示文摘 | Cho Don-Chan Ishii Ryousuke Shizu Keiichiro | 2002 | Electrical Engineering in Japan2002，139，4： | 1 |
| 9 | Experimental simulation of high temperature plasma transport using ahnost dimen- sionally similar cold plasmas in the compact helical sys- tem 显示文摘 | Kazuo T Ryousuke I Masaki T | 2004 | J Plasma Fusion Res Set2004，6，： | 1 |
| 10 | Preparation of plastic spherical microlenses by use of a fluoropolymer stencil and oil-bath heating显示文摘 | Hiromoto Tamura Ryousuke Kojima Hiroaki Usui | 2003 | Applied Optics2003，42，19： | 1 |
| 11 | Polypropylene Laminated Steel Sheet Usable without Painting显示文摘 | Yoshihara Ryoichi Wake Ryousuke Mizoguchi Ryouhei | 2000 | Nippon Steel Technical Report2000，，81： | 1 |
| 12 | Dynamic Multidetector CT of Breast Tumor:Diagnostic Features and Comparision with Conventional Techniques 显示文摘 | Masaaki Inoue Toshiko Sano Ryousuke Watai | 2003 | AJR2003，181，9： | 1 |
| 13 | Structural relaxation accompanied by photo-induced chromatic phase transition of polydiacetylenes with butylene-N-difluorophenyl carbamate side chains显示文摘 | Yuuki Maekawa Naoya Sakamoto Ryousuke Kokado | 2013 | Journal of Luminescence2013，133，： | 1 |
| 14 | Pedestrian detection and tracking in far infrared images显示文摘 | YASUNO M RYOUSUKE S YASUDA N | 2005 | IEEE Transactions on Intelligent Transportation Systems2005，19，2： | 1 |
| 15 | CVD-associated non-coding RNA, ANRIL, modulates expression of atherogenic pathways in VSMC显示文摘 | Ada Congrains Kei Kamide Tomohiro Katsuya Osamu Yasuda Ryousuke Oguro Koichi Yamamoto Mitsuru Ohishi Hiromi Rakugi | 2012 | Biochemical and Biophysical Research Communications2012，，4： | 1 |
| 16 | Salt-inducible kinase 1 influences Na+,K+-ATPase activity in vascular smooth muscle cells and associates with variations in blood pressure显示文摘 | Sergej Popov Angela Silveira Dick W?gs?ter Hiroshi Takemori Ryousuke Oguro Sachiko Matsumoto Ken Sugimoto Kei Kamide Takuo Hirose Michihiro Satoh Hirohito Metoki Masahiro Kikuya Takayoshi Ohkubo Tomohiro Katsuya Hiromi Rakugi Yutaka Imai Fabio Sanchez Mar | 2011 | Journal of Hypertension2011，，12： | 1 |
| 17 | Layer-by-Layer assembled transparent conductive grapheme films for silicon thin films solar cells显示文摘 | Ryousuke Ishikawa Masashi Bando Hidetoshi Wada | 2013 | Japanese Journal of Applied Physics2013，51，11： | 1 |
| 18 | Directed Conversion of Alzheimer’s Disease Patient Skin Fibroblasts into Functional Neurons显示文摘 | Liang Qiang Ryousuke Fujita Toru Yamashita Sergio Angulo Herve Rhinn David Rhee Claudia Doege Lily Chau Laetitia Aubry William B. Vanti Herman Moreno Asa Abeliovich | 2011 | Cell2011，，3： | 1 |
| 19 | Alignment of solid targets under extreme tight focus conditions generated by an ellipsoidal plasma mirror显示文摘The design of ellipsoidal plasma mirrors(EPMs)for the PEARL laser facility is presented.The EPMs achieve a magnification of 0.32 in focal spot size,and the corresponding increase in focused intensity is expected to be about 8.Designing and implementing such focusing optics for short-pulse(<100 fs)systems paves the way for their use in future high-power facilities,where they can be used to achieve intensities beyond 1023W/cm^(2).A retro-imaging-based target alignment system is also described,which is used to align solid targets at the output of the ellispoidal mirrors(with a numerical aperture of 0.75 in this case). | Deepak Kumar Michal Smid Sushil Singh Alexander Soloviev Hannes Bohlin Konstantin Burdonov Gashaw Fente Alexander Kotov Livia Lancia Vit Leedl Sergey Makarov Michael Morrissey Sergey Perevalov Denis Romanovsky Sergey Pikuz Ryousuke Kodama David Neely Paul McKenna Tomas Lastovicka Mikhail Starodubtsev Stefan Weber Motoaki Nakatsutsumi Julien Fuchs | 2019 | Matter and Radiation at Extremes2019，4，2： | 1 |
| 20 | Ginseng enhances contextual fear conditioning and neurogenesis in rats显示文摘 | Chunxiang Qiao Ryousuke D Koutaro K | | 0，，： | 1 |
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