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| 1 | Integrin β4 was downregulated on the airway epithelia of asthma patients显示文摘流上皮的功能的动态平衡的上皮的房间和损失是的航线气喘的主要病理学的特征;然而,位于这些病理下面的机制仍然保持阴暗。我们的以前的工作证明在 integrin 的 5 flanking 区域有三个变化地点 4 在气喘病人,它与 integrin 的减少的表示被相关 4 在外部白血球。Integrin 4 是航线 epithelia 上的一个重要结构的粘附分子保留上皮的房间的结构的粘附。在这个工作,我们进一步表明了 4 表示是的那 integrin 在气喘病人的航线 epithelia 的 downregulated。探查在 integrin 的 imbalanced 表示之间的关系 4 并且航线的机能障碍在气喘的上皮的房间, integrin 4 由 integrin 是在人的支气管的上皮房间(16HBE14O ) 的 silenced 4 小介入的 RNA lentivirus 向量。在 integrin 的 silencing 之上 4, 16HBE14O 房间显示出减少的增长和创伤修理。大多数房间被显示在 integrin 以后在 G1 阶段被逮捕 4 silencing,和增加的 apoptosis 在 integrin 4 沉默房间被导致。在摘要,我们的结果提供了引人注目的证据那 integrin 4 涉及结构的正直和航线的功能的动态平衡上皮的房间。它是可能的 4 在气喘航线 epithelia 上贡献的 integrin 的那 downregulation 航线的结构的混乱和机能障碍上皮的房间。 | Chi Liu Yang Xiang Huijun Liu Yun Li Yurong Tan Xiaolin Zhu DanZeng Menglan Li Liwen Zhang Xiaoqun Qin | 2010 | Acta Biochimica et Biophysica Sinica2010，42，8： | 4 |
| 2 | Hydrothermal exfoliated molybdenum disulfide nanosheets as anode material for lithium ion batteries显示文摘Ultrathin MoS2nanosheets were prepared in high yield using a facile and effective hydrothermal intercalation and exfoliation route. The products were characterized in detail using X-ray diffraction, scanning electron microscopy, transmission electron microscopy and Raman spectroscopy. The results show that the high yield of MoS2nanosheets with good quality was successfully achieved and the dimensions of the immense nanosheets reached 1 μm–2 μm. As anode material for Li-ion batteries, the as-prepared MoS2nanosheets electrodes exhibited a good initial capacity of 1190 mAh g-1and excellent cyclic stability at constant current density of 50 mA g-1. After 50 cycles, it still delivered reversibly sustained high capacities of 750 mAh g-1. | Yundan Liu Long Ren Xiang Qi Liwen Yang Jun Li Yao Wang Jianxin Zhong | 2014 | Journal of Energy Chemistry2014，23，2： | 4 |
| 3 | A Ce-Cu-Ti oxidecatalyst for the selective catalytic reduction of NO with NH3显示文摘 | Gao Xiang Du Xuesen Cui Liwen | 2010 | Catalysis Communications2010，12，： | 1 |
| 4 | Investigation of the effect of Cu addition on the SO2-resistance of a Ce-Ti oxide catalyst for selective catalytic reduction of NO with NH3 显示文摘 | Du Xuesen Gao Xiang Cui Liwen | 2012 | Fuel2012，92，： | 1 |
| 5 | IFN-γ-primed human bone marrow mesenchymal stem cells induce tumor cell apoptosis in vitro via tumor necrosis factor-related apoptosis-inducing ligand显示文摘 | Jingchun Du Liwen Zhou Xiaoyong Chen Sunxing Yan Ming Ke Xiaofang Lu Zhen Wang Weihua Yu Andy Peng Xiang | 2012 | International Journal of Biochemistry and Cell Biology2012，，8： | 1 |
| 6 | A hydrogen peroxide electrochemical sensor based on silver nanoparticles decorated silicon nanowire arrays显示文摘 | Jinjie Yin Xiang Qi Liwen Yang Guolin Hao Jun Li Jianxin Zhong | 2011 | Electrochimica Acta2011，，11： | 1 |
| 7 | Viologen-Decorated TEMPO for Neutral Aqueous Organic Redox Flow Batteries显示文摘A novel electroactive organic molecule,viz.,1-(1-oxyl-2,2,6,6-tetramethylpiperidin-4-yl)-1′-(3-(trimethylammonio)propyl)-4,4′-bipyridinium trichloride((TPABPy)Cl3),is synthesized by decorating 2,2,6,6-tetramethylpiperidin-1-oxyl(TEMPO)with viologen,which is used as the positive electrolyte in neutral aqueous redox flow battery(ARFB).Extensive characterizations are performed to investigate the composition/structure and the electrochemical behavior,revealing the favorable effect of introducing the cationic viologen group on the electroactive TEMPO.Salient findings are as follows.First,the redox potential is elevated from+0.745V for TEMPO to+0.967V for decorated TEMPO,favoring its use as the positive electrolyte.Such an elevation originates from the electron-withdrawing effect of the viologen unit,as evidenced by the nuclear magnetic resonance and single crystal structure analysis.Second,linear sweep voltammetry reveals that the diffusion coefficient is 2:97×10^(−6) cm^(2) s^(−1),and the rate constant of the one-electron transfer process is 7:50×10^(−2) cm s^(−1).The two values are sufficiently high as to ensure low concentration and kinetics polarization losses during the battery operation.Third,the permeability through anion-exchange membrane is as low as 1:80×10^(−11) cm^(2) s^(−1).It is understandable as the positive-charged viologen unit prevents the molecule from permeating through the anion exchange membrane by the Donnan effect.Fourth,the ionic nature features a decent conductivity and thus eliminates the use of additional supporting electrolyte.Finally,a flow battery is operated with 1.50M(TPABPy)Cl3 as the positive electrolyte,which affords a high energy density of 19.0WhL-1 and a stable cycling performance with capacity retention of 99.98%per cycle. | Shuzhi Hu Liwen Wang Xianzhi Yuan Zhipeng Xiang Mingbao Huang Peng Luo Yufeng Liu Zhiyong Fu Zhenxing Liang | 2021 | Energy Material Advances2021，，1： | 1 |
| 8 | The Qinling orogeny and intracontinental orogen mechanisms 显示文摘 | Guowei Zhang Liwen Xiang Qingren Meng | 1995 | Episodes1995，18，12： | 1 |
| 9 | A Ce-Cu-Ti oxide catalyst for the selective catalytic reduction of NO with NH3 显示文摘 | Gao Xiang Du Xuesen Cui Liwen | 2010 | Catalysis Communications2010，12，4： | 1 |
| 10 | Depressive Symptoms and Sleep Duration as Risk Factors for Breast Cancer—China,2020显示文摘Summary What is already known about this topic?Psychological and lifestyle factors are known to potentially play a significant role in the development of breast cancer.However,current evidence-based studies present controversial findings on the associations between depression,sleep duration,and breast cancer risk. | Liyuan Liu Heling Bao Fei Wang Lixiang Yu Shu Cong Fei Zhou Yujuan Xiang Shuya Huang Chao Zheng Liwen Fang Linhong Wang Zhigang Yu | 2023 | China CDC weekly2023，5，15： | 0 |
| 11 | Novel Germoles and Their Ladder-Type Derivatives:Modular Synthesis,Luminescence Tuning,and Electroluminescence显示文摘Considerable effort has been devoted to the design of silicon-containingπ-conjugated materials for application in optoelectronic devices and fluorescent bioimaging.However,the synthesis and spectroscopic tuning of germanium(Ge)-conjugated systems are challenging because of the paucity of synthetically useful methods.Herein,we report a simple and effective method of lithium naphthalenide-induced intramolecular cyclization to construct architecturally diverse Ge-containingπ-conjugated molecules,including benzogermoles and their ladder-type derivatives,with high yields of up to 92%.The photophysical properties of these molecules can befinely controlled by the introduction of electrondonating or-withdrawing substituents,and intense luminescence ranging from deep-blue to red regions in the solid state was observed.A quantitative model based on the Hammett constant against the luminescence wavelength showed a good linear correlation,allowing us to reliably predict and design luminescent materials with specific properties for applications.Notably,Ge-bridged ladder-type derivatives exhibited high photoluminescence and efficient deep-blue electroluminescence with good color purity.We believe this study will open a new avenue to organogermanium chemistry and offers greater flexibility for electronic structural tuning. | Xiaoshuang Xiang Zhikuan Zhou Xing Wu Zhigang Ni Lizhi Gai Xuqiong Xiao Liwen Xu Zujin Zhao Hua Lu Zijian Guo | 2022 | CCS Chemistry2022，4，12： | 0 |
| 12 | Expression, refolding and preliminary characterization of recombinant snake venom metalloproteinases: Implica- tion for the hemorrhagic mechanism显示文摘Two cDNAs encoding hemorrhagic snake venom metalloproteinase acutolysin A and non-hemorrhagic metalloproteinase (BR) were cloned into the expression vector pET-22b, respectively, and the corresponding two recombinant proteins, A-22b and BR-22b, were produced in inclusion bodies in E. coli BL21(DE3). The recombinant proteins were then subjected to solubilization, purification and refolding in vitro. A-22b showed hemorrhagic activity but no detectable proteolytic activities toward fibrinogen and fibronectin. Natural acutolysin A had both hemorrhagic activity and proteolytic activity toward these substrates. BR-22b showed the proteolytic activities toward fibrinogen, but no hemorrhagic activity. In addition, two chimeric genes, C1 and C2, were constructed and cloned into pET-22b, and the corresponding recombinant proteins, C1-22b and C2-22b, were also expressed in inclusion bodies. C1-22b involved N-terminal 110 amino acids of BR and C-terminal 95 amino acids of acutolysin A, while C2-22b contained N-terminal 108 amino acids of acutolysin A and C-terminal 112 amino acids of BR. The biological activities of C2-22b and C1-22b were similar to those of A-22b and BR-22b, respectively. Our results suggested that N-terminal major subdomain of a snake venom metalloproteinase might play a key role in hemorrhagic activity and have an appreciable effect on the selectivity for protein substrates. | XIANG Kaijun, ZOU Chunsen, ZHU Zhiqiang, TENG Maikun, NIU Liwen & LIU Jing School of Life Science, University of Science and Technology of China, Hefei 230027, China | 2003 | Chinese Science Bulletin2003，48，19： | 0 |
| 13 | ALDOB介导的果糖代谢促进肠癌肝转移的代谢重编程显示文摘文章简介各类恶性肿瘤中结直肠癌新生发病率(10.2%)位居第三,致死率(9.2%)位居第二。肠癌转移后5年存活率小于10%,是造成肠癌患者死亡的主要原因,也是肠癌治疗的困难所在。肝脏是肠癌主要的转移器官,大约70%转移向肝脏。那么肠癌细胞转移到肝脏以后. | 卜鹏程 Kai-Yuan Chen Kun Xiang Christelle Johnson Scott B.Crown Nikolai Rakhilin Yiwei Ai Lihua Wang Rui Xi Inna Astapova Yan Han Jiahe Li Bradley B.Barth Min Lu Ziyang Gao Robert Mines Liwen Zhang Mark Herman David Hsu Guo-Fang Zhang Xiling Shen | 2019 | 科学新闻2019，0，2： | 0 |
| 14 | Study on the Present Situation and Influencing Factors of Farmers'Agricultural Insurance Demand in Poverty-Stricken Mountainous Areas显示文摘Agricultural insurance can avoid the risks of agricultural production and operation to a large extent,promote agricultural development and increase farmers'income,and lay a solid foundation for rural revitalization.At present,China's agricultural insurance is in the stage of all-round development,and there are still many problems,especially the farmers'mistrust of agricultural insurance and their weak willingness to participate in agricultural insurance.Based on the data and information obtained from the field visit and questionnaire survey in Enshi Prefecture,this paper makes an empirical analysis on the factors affecting farmers'agricultural insurance demand by using binary Logistic regression model.According to the conclusion of the analysis,this paper puts forward the corresponding measures and suggestions from the three dimensions of the government,insurance companies and farmers. | Liu YANG Liwen XIANG Jing ZENG | 2020 | Asian Agricultural Research2020，12，4： | 0 |
| 15 | An efficient metatranscriptomic approach for capturing RNA virome and its application to SARS-CoV-2显示文摘Coronavirus disease 2019(COVID-19)is a new type of respiratory disease caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),which has caused severe social and economic costs and has become a great threat to public health because of the high mortality rate.Recent studies indicated that respiratory pathogens co-infection and secondary infection were critical risk factors for the severity and mortality rates of COVID-19(Zhou et al.,2020). | Yao Meng Liwen Xiao Wenbing Chen Fangqing Zhao Xiang Zhao | 2021 | Journal of Genetics and Genomics2021，48，9： | 0 |
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