4篇
您的检索式：作者名="Yurong Tan"
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| 1 | Integrin β4 was downregulated on the airway epithelia of asthma patients显示文摘流上皮的功能的动态平衡的上皮的房间和损失是的航线气喘的主要病理学的特征;然而,位于这些病理下面的机制仍然保持阴暗。我们的以前的工作证明在 integrin 的 5 flanking 区域有三个变化地点 4 在气喘病人,它与 integrin 的减少的表示被相关 4 在外部白血球。Integrin 4 是航线 epithelia 上的一个重要结构的粘附分子保留上皮的房间的结构的粘附。在这个工作,我们进一步表明了 4 表示是的那 integrin 在气喘病人的航线 epithelia 的 downregulated。探查在 integrin 的 imbalanced 表示之间的关系 4 并且航线的机能障碍在气喘的上皮的房间, integrin 4 由 integrin 是在人的支气管的上皮房间(16HBE14O ) 的 silenced 4 小介入的 RNA lentivirus 向量。在 integrin 的 silencing 之上 4, 16HBE14O 房间显示出减少的增长和创伤修理。大多数房间被显示在 integrin 以后在 G1 阶段被逮捕 4 silencing,和增加的 apoptosis 在 integrin 4 沉默房间被导致。在摘要,我们的结果提供了引人注目的证据那 integrin 4 涉及结构的正直和航线的功能的动态平衡上皮的房间。它是可能的 4 在气喘航线 epithelia 上贡献的 integrin 的那 downregulation 航线的结构的混乱和机能障碍上皮的房间。 | Chi Liu Yang Xiang Huijun Liu Yun Li Yurong Tan Xiaolin Zhu DanZeng Menglan Li Liwen Zhang Xiaoqun Qin | 2010 | Acta Biochimica et Biophysica Sinica2010，42，8： | 4 |
| 2 | Notch activation induces endothelial cell senescence and pro-inflammatory response: Implication of Notch signaling in atherosclerosis显示文摘 | Zhao-Jun Liu Yurong Tan Gary W. Beecham David M. Seo Runxia Tian Yan Li Roberto I. Vazquez-Padron Margaret Pericak-Vance Jeffery M. Vance Pascal J. Goldschmidt-Clermont Alan S. Livingstone Omaida C. Velazquez | 2012 | Atherosclerosis2012，，2： | 1 |
| 3 | Rheological behaviour of ethylene glycol based titania nanofluids显示文摘 | Haisheng Chen Yulong Ding Yurong He Chunqing Tan | 2007 | Chemical Physics Letters2007，，4： | 1 |
| 4 | FGD5 as a novel prognostic biomarker and its association with immune infiltrates in lung adenocarcinoma显示文摘Background:Non-small cell lung cancer(NSCLC)has a poor prognosis with a low 5-year survival rate.Lung adenocarcinoma(LUAD)accounts for 50%.Facio-genital dysplasia-5(FGD5),a member of a subfamily of Rho GTPGDP exchange factors,may be a good molecular biomarker for diagnosis and prognosis.Objective:To explore the clinical application of FGD5,the study was designed to investigate the prognosis value of FGD5 expression and its correlation with immune infiltrates in LUAD patients.Methods:Through the Wilcoxon signed-rank test and logistic regression,the correlation between clinical characteristics and FGD5 expression was analyzed.Kaplan-Meier plotter analysis,Cox regression,and a receiver operating characteristic(ROC)curve were constructed to evaluate the influence of FGD5 on prognosis.The function of FGD5 in lung cancer was analyzed using Gene set enrichment analysis(GSEA)and Single Sample Gene Set Enrichment Analysis(ssGSEA).Results:Compared to normal tissues,FGD5 was downregulated in LUAD.FGD5 may be a potential diagnostic and prognostic biomarker of lung cancer for its association with improved overall survival(OS),progression-free interval(PFI),and disease-specific survival(DSS)in LUAD.Results of functional analysis suggested that FGD5 was involved in the immune response for its association with immune infiltration.Conclusion:FGD5 may be a significant molecular biomarker for diagnosis and prognosis,presenting as an independent prognostic risk factor for LUAD. | ZHONGXIANG TANG LILI WANG GUOJUN WU LING QIN YURONG TAN | 2023 | BIOCELL2023，47，11： | 0 |
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