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| 1 | A spatial-temporal analysis of urban recreational business districts: A case study in Beijing, China显示文摘这研究在北京在娱乐商业区(RBD ) 揭示了空间时间的变化并且检验了在地点之间的关系城市的 RBD 和交通条件,居民和旅游密度,舞台的点,和土地定价。城市的 RBD (最低有效字符,每秒字符数,和 ULA ) 的一个更合理的分类也被建议。象 Gini 系数,空间插值,核密度评价,和地理察觉者那样的量的方法被采用分别地,在 1990 , 2000 ,和 2014 在北京从城市的 RBD 的三种类型收集并且分析数据并且象城市的 RBD 的分发特征一样的空间时间的模式用 ArcGIS 软件被分析。(1 ) 在北京的城市的 RBD 的数字和规模一直在膨胀,为所有的趋势城市的 RBD 录入空间地要聚结的北京,这被结束持续;(2 ) 在北京的城市的 RBD 的空间时间的进化模式是单个核心的 agglomerationdual 核心 agglomerationmulti 核心散开;并且(3 ) 城市的 RBD 总是与低交通密度,旅游胜地,高级居民和旅游人口密度位于区域,并且高相对打估价;这些因素也影响 RBD 的规模尺寸。 | ZHU He LIU Jiaming CHEN Chen LIN Jing TAO Hui | 2015 | Journal of Geographical Sciences2015，25，12： | 14 |
| 2 | The record of paleoclimatic change from stalagmites and the determination of termination II in the south of Guizhou Province, China显示文摘A high-resolution climate record from 163.00 kaBP to 113.80 kaBP has been obtained through TIMS-U series dating and carbon and oxygen isotope analysis of the three large stalagmites from two caves in the south of Guizhou Province, China. The record of the oxygen isotopes from the stalagmites reveals that the undulation characteristics between the cooling event of the glacial period and the warming event of the interglacial period in the research area can compare well to those of ice cores, lake sediments, loess and deep sea sediments on the scale of ten-thousand years or millennium time scale. The climate undulation provided by the record of the stalagmites has a coherence with the global changes and a tele-connection to the paleoclimate changes in the north polar region. Our results suggest that the direct dynamics of paleo-monsoon circulation changes reflected in the record of the stalagmites might be caused by changes of the global ice volume, and in turn related to various factors, including the solar radiation strength at the mid-latitudes in the Northern Hemisphere, the southern extension of the ice-rafted event in the North Atlantic, and changes of the equatorial Pacific sea surface temperature at the low-latitudes. Using δ18O values, we have calculated the temperatures and the results show that the temperature difference between the penultimate glacial period (with an average temperature of 8.1℃, and a minimum temperature range from 0.65℃ to -1.43℃ at stage 6 ) and the last interglacial period (with an average temperature of 18.24℃ at sub-stage 5e ) was about 10℃. This temperature difference from the record of the stalagmites corresponds in general to the record temperature variation (about 10℃) of measured ice cores. The climate records from the three stalagmites in the two caves have shown that the circulation strength of the Asian summer monsoon and the winter monsoon in the penultimate glacial period and the last interglacial period had a clear change. With the TIMS-U series method, termination II of the penultimate glacial period has been precisely dated at an age of (129.28±1.10) kaBP for the three stalagmites in the south of Guizhou Province, China. This borderline age represents the beginning of the last interglacial period or the boundary between the Middle Pleistocene and the Late Pleistocene, and corresponds to the beginning age of the last interglacial period shown by the ice cores and in the SPECMAP curve of the marine oxygen isotopes. The chronology determination of termination II is not only of stratigraphic and chronological significance, but also lays an important foundation for discussing the short time scales of climate oscillation and rapidly changing events of paleoclimate in the circulation region of the East Asian monsoon. | ZHANG Meiliang, YUAN Daoxian1, LIN Yushi, CHENG Hai, QIN Jiaming &ZHANG HuilingKarst Dynamics Laboratory, Institute of Karst Geology, Chinese Academy of Geological Sciences, Guilin 541004, China Geography Department, Minnesota University, MN 55455, USA Correspondence should be addressed to Zhang Meiliang | 2004 | Science China Earth Sciences2004，47，1： | 9 |
| 3 | Interferon-armed RBD dimer enhances the immunogenicity of RBD for sterilizing immunity against SARS-CoV-2显示文摘Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)has caused a global crisis,urgently necessitating the development of safe,efficacious,convenient-to-store,and low-cost vaccine options.A major challenge is that the receptor-binding domain(RBD)-only vaccine fails to trigger long-lasting protective immunity if used alone for vaccination. | Shiyu Sun Yueqi Cai Tian-Zhang Song Yang Pu Lin Cheng Hairong Xu Jing Sun Chaoyang Meng Yifan Lin Haibin Huang Fang Zhao Silin Zhang Yu Gao Jian-Bao Han Xiao-Li Feng Dan-Dan Yu Yalan Zhu Pu Gao Haidong Tang Jincun Zhao Zheng Zhang Jiaming Yang Zhenxiang Hu Yang-Xin Fu Yong-Tang Zheng Hua Peng | 2021 | Cell Research2021，31，9： | 7 |
| 4 | Incidence and clinical characteristics of inflammatory bowel disease in a developed region of G uangdong P rovince, C hina: A prospective population‐based study显示文摘 | Zhirong Zeng Zhenhua Zhu Yuyu Yang Weishan Ruan Xiabiao Peng Yuhuan Su Lin Peng Jinquan Chen Quan Yin Chao Zhao Haihua Zhou Shuai Yuan Yuantao Hao Jiaming Qian Siew Chien Ng Minhu Chen Pinjin Hu | 2013 | J Gastroenterol Hepatol2013，，7： | 5 |
| 5 | Anatomical variation of infra-pyloric artery origination: A prospective multicenter observational study (IPA-Origin)显示文摘Objective: Infra-pyloric artery(IPA) is an important anatomical landmark in treatment of gastric cancer and is the key vessel for pylorus-preserving gastrectomy and subgroup of infra-pyloric lymph nodes. However, its anatomical variation is not thoroughly understood. Our study aimed to clarify the origination of the IPA.Methods: We did this prospective, multicenter, open-label, observational study at gastric surgery departments of34 hospitals in China. Gastric cancer patients aged 18 years or older and scheduled to undergo elective total or distal gastrectomy were assigned. During the surgery, IPA dissecting and exposing the origination point with photographs or video clips were required. The primary outcome was the origination of the IPA. Analysis of variance, χ~2 tests and Fisher's tests were used to analyze the differences between groups. The study is registered at Clinicaltrials.gov(No. NCT03071237).Results: Between May 8 and July 31, 2017, 429 patients were assigned for the study, and 419(97.7%) patients had the IPA dissected and recorded through photograph or video and were included in the primary outcome analysis. The median age was 62 years old, and 73.7% were male. Among the patients, 78.5% received laparoscopic surgery. Single IPA origination was identified in 398(95.0%) patients, including gastroduodenal artery(GDA) in154(36.8%) patients, anterior superior pancreaticoduodenal artery(ASPDA) in 130(31.0%) patients, and right gastroepiploic artery(RGEA) in 114(27.2%) patients. Fifteen(3.6%) patients were identified with multiple IPA and 6(1.4%) patients were identified as IPA absence. The differences in the distribution of surgical approach(P=0.003) and geographic area(P=0.030) were statistically significant. No difference was shown in sex, age,gastrectomy type, tumor location, and clinical T, N and M stage.Conclusions: Our study found that the IPA originates from GDA, ASPDA and RGEA in similar proportions.Laparoscopic surgery may be more helpful in dissection of the IPA than open surgery. | Rulin Miao Jianjun Qu Zhengrong Li Daguang Wang Jiang Yu Weidong Zang Yong Li Fenglin Liu Jian Zhang Wu Song Kai Ye Su Yan Wei Wang Shuangyi Ren Lu Zang Changqing Jing Li Zhang Kuan Wang Weihua Fu Lin Fan Bin Liang Gang Zhao Jun Cai Li Yang Jiaming Zhu Jun You Kun Yang Qingxing Huang Zhaojian Niu Ning Ning Xingfeng Qiu Gang Ji Feng Liang Hua Huang Chao Gao Fei Shan Shuangxi Li Yongning Jia Lianhai Zhang Xiangji Ying Yan Zhang Zhaode Bu Xiangqian Su Gang Zhao Ziyu Li Jiafu Ji | 2018 | Chinese Journal of Cancer Research2018，30，5： | 5 |
| 6 | Precise temporal regulation of Dux is important for embryo development显示文摘Dear Editor,Zygotic genome activation(ZGA)following fertilization is accomplished through a process termed the maternal-to-zygotic transition,during which the maternal RNAs and proteins are degraded and zygotic genome is transcriptionally activated.In mice,minor ZGA occurs from S phase of the zygote to G1 phase of the two-cell(2C)embryo,while major ZGA takes place during the middle-to-late 2C stage with a burst of transcription of totipotent cleavage stage-specific genes and retrotransposons. | Mingyue Guo Yanping Zhang Jianfeng Zhou Yan Bi Junqin Xu Ce Xu Xiaochen Kou Yanhong Zhao Yanhe Li Zhifen Tu Kuisheng Liu Jiaming Lin Peng Yang Shaorong Gao Yixuan Wang | 2019 | Cell Research2019，29，11： | 5 |
| 7 | A high-resolution, absolute-dated Holocene and deglacial Asian monsoon record from Dongge Cave, China显示文摘 | Carolyn A. Dykoski R. Lawrence Edwards Hai Cheng Daoxian Yuan Yanjun Cai Meiliang Zhang Yushi Lin Jiaming Qing Zhisheng An Justin Revenaugh | 2005 | Earth and Planetary Science Letters2005，，1： | 3 |
| 8 | Corrosion Mechanism of 5083 Aluminum Alloy in Seawater Containing Phosphate显示文摘As a material with good corrosion resistance,5083 aluminum alloy has a great application prospect in marine environment.In this work,the corrosion characteristics of 5083 aluminum alloy in seawater containing phosphate were investigated with Potentiodynamic Polarization,Electrochemical Impedance Spectroscopy (EIS),Scanning Electron Microscope (SEM),Energy Dispersive Spectroscopy Analysis (EDSA),X-ray Photoelectron Spectroscopy (XPS) and Laser Confocal Microscope.The results indicated that the effects of phosphate in seawater were two-fold.Firstly,phosphate slightly accelerated the corrosion of 5083 in seawater in the early stage of corrosion.HPO_4~(2-)competed with OH~-in the adsorption process on the alloy surface,which weakened the contact between OH~-and Al~(3+)near the interface of the alloy,and inhibited the formation as well as the self-repair of the passive film,thus accelerating the activation dissolution process.Compared with the natural seawater,the charge transfer resistance of 5083 in the seawater containing phosphate decreased faster during the early stage of corrosion,and the corrosion current density i_(corr) was higher in seawater containing phosphate.On the other hand,the addition of phosphate would not affect the cluster distribution of the second phase of 5083 in seawater,but it changed the composition of the corrosion product layer and had an obvious inhibitory effect on the local corrosion of 5083 in seawater.After 16-day exposure,shallower and more sparsely distributed pits could be observed on the derusted surface of 5083 in the seawater containing phosphate,and the pitting coefficient in the seawater containing phosphate was significantly lower than that in natural seawater.The reduction of pitting tendency could be realized mainly through two ways.First,the HPO_4~(2-)adsorbed on the surface of the passive film in the early stage of corrosion and repeled the corrosive anions such as Cl~-.Second,phosphate participated in the construction of the Ca HPO_4 precipitation film,which acted as a barrier and protection. | WANG Jiaming YANG Haodong DU Min HOU Jian PENG Wenshan LIN Cunguo | 2021 | Journal of Ocean University of China2021，20，2： | 3 |
| 9 | Potential therapeutic effects and applications of Eucommiae Folium in secondary hypertension显示文摘Eucommiae Folium(EF),a traditional Chinese medicine,has been used to treat secondary hypertension,including renal hypertension and salt-sensitive hypertension,as well as hypertension caused by thoracic aortic endothelial dysfunction,a high-fat diet,and oxidized low-density lipoprotein.The antihypertensive components of EF are divided into four categories:flavonoids,iridoids,lignans,and phenylpropanoids,such as chlorogenic acid,geniposide acid and pinoresinol diglucoside.EF regulates the occurrence and development of hypertension by regulating biological processes,such as inhibiting inflammation,regulating the nitric oxide synthase pathway,reducing oxidative stress levels,regulating endothelial vasoactive factors,and lowering blood pressure.However,its molecular antihypertensive mechanisms are still unclear and require further investigation.In this review,by consulting the relevant literature on the antihypertensive effects of EF and using network pharmacology,we summarized the active ingredients and pharmacological mechanisms of EF in the treatment of hypertension to clarify how EF is associated with secondary hypertension,the related components,and underlying mechanisms.The results of the network pharmacology analysis indicated that EF treats hypertension through a multicomponent,multi-target and multi-pathway mechanism.In particular,we discussed the role of EF targets in the treatment of hypertension,including epithelial sodium channel,heat shock protein70,rhoassociated protein kinase 1,catalase,and superoxide dismutase.The relevant signal transduction pathways,the ras homolog family member A(RhoA)/Rho-associated protein kinase(ROCK)and nicotinamide adenine dinucleotide phosphate(NADPH)oxidase/eNOS/NO/Ca^(2+)pathways,are also discussed. | Mengyuan Li Yanchao Zheng Sha Deng Tian Yu Yucong Ma Jiaming Ge Jiarong Li Xiankuan Li Lin Ma | 2022 | Journal of Pharmaceutical Analysis2022，12，5： | 2 |
| 10 | Biomarkers of aging显示文摘Aging biomarkers are a combination of biological parameters to(i)assess age-related changes,(ii)track the physiological aging process,and(iii)predict the transition into a pathological status.Although a broad spectrum of aging biomarkers has been developed,their potential uses and limitations remain poorly characterized.An immediate goal of biomarkers is to help us answer the following three fundamental questions in aging research:How old are we?Why do we get old?And how can we age slower?This review aims to address this need.Here,we summarize our current knowledge of biomarkers developed for cellular,organ,and organismal levels of aging,comprising six pillars:physiological characteristics,medical imaging,histological features,cellular alterations,molecular changes,and secretory factors.To fulfill all these requisites,we propose that aging biomarkers should qualify for being specific,systemic,and clinically relevant. | Aging Biomarker Consortium Hainan Bao Jiani Cao Mengting Chen Min Chen Wei Chen Xiao Chen Yanhao Chen Yu Chen Yutian Chen Zhiyang Chen Jagadish K Chhetri Yingjie Ding Junlin Feng Jun Guo Mengmeng Guo Chuting He Yujuan Jia Haiping Jiang Ying Jing Dingfeng Li Jiaming Li Jingyi Li Qinhao Liang Rui Liang Feng Liu Xiaoqian Liu Zuojun Liu Oscar Junhong Luo Jianwei Lv Jingyi Ma Kehang Mao Jiawei Nie Xinhua Qiao Xinpei Sun Xiaoqiang Tang Jianfang Wang Qiaoran Wang Siyuan Wang Xuan Wang Yaning Wang Yuhan Wang Rimo Wu Kai Xia Fu-Hui Xiao Lingyan Xu Yingying Xu Haoteng Yan Liang Yang Ruici Yang Yuanxin Yang Yilin Ying Le Zhang Weiwei Zhang Wenwan Zhang Xing Zhang Zhuo Zhang Min Zhou Rui Zhou Qingchen Zhu Zhengmao Zhu Feng Cao Zhongwei Cao Piu Chan Chang Chen Guobing Chen Hou-Zao Chen Jun Chen Weimin Ci Bi-Sen Ding Qiurong Ding Feng Gao Jing-Dong JHan Kai Huang Zhenyu Ju Qing-Peng Kong Ji Li Jian Li Xin Li Baohua Liu Feng Liu Lin Liu Qiang Liu Qiang Liu Xingguo Liu Yong Liu Xianghang Luo Shuai Ma Xinran Ma Zhiyong Mao Jing Nie Yaojin Peng Jing Qu Jie Ren Ruibao Ren Moshi Song Zhou Songyang Yi Eve Sun Yu Sun Mei Tian Shusen Wang Si Wang Xia Wang Xiaoning Wang Yan-Jiang Wang Yunfang Wang Catherine CL Wong Andy Peng Xiang Yichuan Xiao Zhengwei Xie Daichao Xu Jing Ye Rui Yue Cuntai Zhang Hongbo Zhang Liang Zhang Weiqi Zhang Yong Zhang Yun-Wu Zhang Zhuohua Zhang Tongbiao Zhao Yuzheng Zhao Dahai Zhu Weiguo Zou Gang Pei Guang-Hui Liu | 2023 | Science China(Life Sciences)2023，66，5： | 2 |
| 11 | HEp-2 image classification using intensity order pooling based features and bag of words显示文摘 | SHEN Linlin LIN Jiaming WU Shengyin | 2013 | Pattern Recognition2013，47，7： | 1 |
| 12 | The record of paleoclimatic change from stalacmites and the determination of termination Ⅱ the south of Guizhou province,China显示文摘 | Zhang Meiliang Lin Yushi Qin Jiaming | 2002 | Science in China Series D (in Chinese)2002，32，11： | 1 |
| 13 | Distortion Measurement of CCD Imaging System with Short Focal Length and Large-field Objective显示文摘 | Lin Jiaming Xing Mailing Sha Dingguo | 2005 | Optics and Lasers in Engineering2005，43，10： | 1 |
| 14 | Flexible temperature sensor with high sensitivity ranging from liquid nitrogen temperature to 1200℃显示文摘Flexible temperature sensors have been extensively investigated due to their prospect of wide application in various flexible electronic products.However,most of the current flexible temperature sensors only work well in a narrow temperature range,with their application at high or low temperatures still being a big challenge.This work proposes a flexible thermocouple temperature sensor based on aerogel blanket substrate,the temperature-sensitive layer of which uses the screen-printing technology to prepare indium oxide and indium tin oxide.It has good temperature sensitivity,with the test sensitivity reaching 226.7μV℃^(−1).Most importantly,it can work in a wide temperature range,from extremely low temperatures down to liquid nitrogen temperature to high temperatures up to 1200℃,which is difficult to be achieved by other existing flexible temperature sensors.This temperature sensor has huge application potential in biomedicine,aerospace and other fields. | Zhaojun Liu Bian Tian Zhuangde Jiang Shuimin Li Jiaming Lei Zhongkai Zhang Jiangjiang Liu Peng Shi Qijing Lin | 2023 | International Journal of Extreme Manufacturing2023，5，1： | 1 |
| 15 | Sensorless IPMSM drive system using saliency back-EMF-based intelligent torque observer with MTPA controln显示文摘 | Lin F J Hung Yingchih Chen Jiaming | 2014 | IEEE Transactions on Industrial Informatics2014，10，2： | 1 |
| 16 | Signal-to- noise Ratio Evaluation of a CCD Camera显示文摘 | Chen Lingfeng Zhang Xusheng Lin Jiaming | 2009 | Optics & Laser Technology2009，41，5： | 1 |
| 17 | A high-resolution,absolute-dated Holocene and deglacial Asian monsoon record from Dongge Cave,China显示文摘 | Dykoski C A Edwards R L Cheng Hai Yuan Daoxian Cai Yanjun Zhang Meiliang Lin Yushi Qing Jiaming An Zhisheng Revenangh J | | 0，，1： | 1 |
| 18 | Optimisation method for carbon black distribution of polypropylene-based semi-conductive screen materials and its effect on charge emission behaviour at screen/insulation interface显示文摘The semi-conductive(SC)screen materials used in polypropylene(PP)-based cables are usually multi-component composites.Polypropylene shows poor compatibility with carbon black(CB),and CB particles tend to disperse in the elastomer phase,which results in CB non-uniform dispersion in screen materials.The non-uniform distribution of CB will cause abnormal electric fields at the screen/insulation interface and affect insulation performance.This paper prepared modified PP grafted by molecule maleic anhydride,and four PP-based SC shielding materials were blended in combination with PP,PP-g-MAH,and thermoplastic elastomer(POE)as matrix resin.The CB distribution,electrical conductivity,and basic physical properties of the shielding material were characterised.Different screen materials were served as electrodes to test their effects on the space charge and conductivity characteristics of insulation.The relationship between the macroscopic properties and the distribution characteristics of CB was discussed.Results show that the selective dispersion of CB in screen material was improved by PPg-MAH and the surface electric potential distribution was homogenised.Charge emission at the screen/insulation interface and conductivity can be reduced by homogenising the CB distribution.CB/PP-g-MAH/POE prepared in this paper exhibits relatively uniform CB distribution,which can reduce the charge emission from the screen/insulation interface. | Jiaming Yang Rui Zhang Xu Yang Zhi Sun Xindong Zhao Hong Zhao Xuan Wang Lin Li Heqian Liu | 2023 | High Voltage2023，8，2： | 1 |
| 19 | Optimization of Extraction Process and Determination of Antioxidant Activity of Myrica ruba Leaf Pigment by Orthogonal Design显示文摘[Objectives] To determine the optimum conditions and antioxidant activity of Myrica ruba leaf pigment,and provide reference for further development and use of Myrica ruba leaves. [Methods]Pigment of Myrica ruba leaves was extracted by ethanol extraction method. Absorbance was measured at wavelength of 300 nm. Effects of ethanol volume fraction,solid-to-liquid ratio,temperature,and extraction time were studied. L_9( 3~3) orthogonal experiment was carried out to optimize the extraction process,and DPPH scavenging ability was measured.[Results]The optimum extraction process of Myrica ruba leaf pigment was as follows: the ethanol volume fraction was 50%; the solid-to-liquid ratio was 1: 60( w/v),extraction temperature 70℃; extraction time was 60 min; after the concentration of purified Myrica ruba leaf pigment reached 0. 4455 mg/mL,the DPPH scavenging ability was basically the same as the same concentration Vc.[Conclusions] The experiment indicates that the optimized extraction process has a high yield rate,and Myrica ruba leaf pigment has high anti-oxidant activity. | Gongxiao MO Mengyao LIN Jiaming WANG Yuandan LAN Xunjie LIANG Xiang WANG Qiumeng WEI Suoyi HUANG | 2017 | Medicinal Plant2017，8，5： | 1 |
| 20 | Timing, duration, and transitions of the last interglacial Asian monsoon 显示文摘 | Yuan Daoxian Cheng Hai Edwards R L Dykoski C A Kelly M J Zhang Meiliang Qing Jiaming Lin Yushi Wang Yongjin Wu Jiangyin Dorale J A An Zhisheng Cai Yanjun | 2004 | Science2004，304，5670： | 1 |
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