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| 1 | Recurrence and Outcomes Following Hepatic Resection, Radiofrequency Ablation, and Combined Resection/Ablation for Colorectal Liver Metastases显示文摘 | Eddie K. Abdalla Jean-Nicolas Vauthey Lee M. Ellis Vickie Ellis Raphael Pollock Kristine R. Broglio Kenneth Hess Steven A. Curley | 2004 | Annals of Surgery2004，，6： | 3 |
| 2 | Biomarker-guided sequential targeted therapies to overcome therapy resistance in rapidly evolving highly aggressive mammary tumors显示文摘组合指向的治疗在由堵住治疗癌症是更有效的绕过机制或导致的合成致命性。然而,他们的临床的申请被抵抗和毒性妨碍。遇见这重要挑战,我们用 ErbB2-overexpressing/PTEN-low 开发了并且测试各种各样的指向的治疗的指导 biomarker 的顺序的应用程序的一个新奇概念,高度好攻击的乳癌作为我们的模型。惊人地,从遗传上设计的鼠标与 intratumoral 异质从病人和乳房的肿瘤在两 PTEN-low/trastuzumab-resistant 乳癌支撑了 ErbB2 和下游的小径驱动器 trastuzumab 抵抗的激活。尽管 lapatinib 开始禁止了 trastuzumab 抵抗的鼠标肿瘤,肿瘤由激活表明由量的蛋白质数组出现的网络的 PI3K/mTOR 绕过抑制。有趣地,小径也是的 mTOR 的激活在 neoadjuvant 观察了表明 lapatinib 抵抗的对待 lapatinib 的病人。Trastuzumab + lapatinib 抵抗被一个 PI3K/mTOR 双 kinase 禁止者(BEZ235 ) 的顺序的申请有效地没有重要毒性克服。然而,我们的 p-RTK 数组分析证明 BEZ235 治疗在遗传上设计的老鼠肿瘤导致了增加的 ErbB2 表示和 phosphorylation,导致 BEZ235 抵抗并且在 3-D,然而并非 2-D,文化。机械学地,我们作为 BEZ235 抵抗的新奇机制识别了 ErbB2 蛋白质稳定和激活,它被随后的治疗与 lapatinib + BEZ235 联合颠倒。显著地, biomarker 指导的指向的治疗的这个顺序的应用程序在很快发展加倍的抵抗的肿瘤改变忍受极其好攻击的肿瘤的鼠标的寿命。使用的这条根本上新奇的途径有效地在一个顺序的顺序罐头指向了治疗目标和改编在在治疗期间发展抵抗的癌症的发信号的网络。 | Ozgur Sahin Qingfei Wang Samuel W Brady Kenneth Ellis Hai Wang Chia-Chi Chang Qingling Zhang Preety Priya Rui Zhu Stephen T Wong Melissa D Landis William J Muller Francisco J Esteva Jenny Chang Dihua Yu | 2014 | Cell Research2014，24，5： | 2 |
| 3 | Human Body Composition: In Vivo Meth- ods 显示文摘 | Kenneth J Ellis | 2000 | The American Physiological Society :2000，2，80： | 1 |
| 4 | A phase I and pharmacology study of an oral platinum complex, JM216: dose-dependent pharmacokinetics with single-dose administration显示文摘 | Mark J. McKeage Prakash Mistry Janet Ward Frances E. Boxall Swee Loh Ciaran O’Neill Paul Ellis Lloyd R. Kelland Sarah E. Morgan Barry Murrer Pedro Santabarbara Kenneth R. Harrap Ian R. Judson | 1995 | Cancer Chemotherapy and Pharmacology1995，，6： | 1 |
| 5 | A longitudinal study evaluating the effects of interferon-alpha therapy on cognitive and psychiatric function in adults with chronic hepatitis C显示文摘 | Marilyn Huckans Bret Fuller Viva Wheaton Sarah Jaehnert Carilyn Ellis Michael Kolessar Daniel Kriz Jeanne Renee Anderson Kristin Berggren Hannah Olavarria Anna W. Sasaki Michael Chang Kenneth D. Flora Jennifer M. Loftis | 2014 | Journal of Psychosomatic Research2014，，： | 1 |
| 6 | Composition of gestational weight gain impacts maternal fat retention and infant birth weight显示文摘 | Nancy F Butte Kenneth J Ellis William W Wong Judy M Hopkinson E.O’Brian Smith | 2003 | American Journal of Obstetrics and Gynecology2003，，： | 1 |
| 7 | Dose father ab- sence place daughters at special risk for early sexual activity and teenage pregnancy显示文摘 | Ellis Bruce J John BE Kenneth DA | | 0，，03： | 1 |
| 8 | Endovascular repair of abdominal aortic aneurysms: Device-specific outcome显示文摘 | Kenneth Ouriel Daniel G. Clair Roy K. Greenberg Sean P. Lyden Patrick J. O’Hara Timur P. Sarac Sunita D. Srivastava Brett Butler Ellis S.K. Sampram | 2003 | Journal of Vascular Surgery2003，，： | 1 |
| 9 | Human body composition: in vivo methods显示文摘 | Kenneth J Ellis | 2000 | Physiol Rev2000，80，1： | 1 |
| 10 | Investigation of the Safety of Irreversible Electroporation in Humans显示文摘 | Kenneth R. Thomson Wa Cheung Samantha J. Ellis Dean Federman Helen Kavnoudias Deirdre Loader-Oliver Stuart Roberts Peter Evans Christine Ball Andrew Haydon | 2011 | Journal of Vascular and Interventional Radiology2011，，5： | 1 |
| 11 | Composition of gestational weight gain impacts maternal fat retention and infant birth weight 显示文摘 | Nancy F Butte Kenneth J Ellis William W Wong | 2003 | Am J Obstet Gyneco2003，189，： | 1 |
| 12 | Recurrence and Outcomes Following Hepatic Resection, Radiofrequency Ablation, and Combined Resection/Ablation for Colorectal Liver Metastases显示文摘 | Eddie K. Abdalla Jean-Nicolas Vauthey Lee M. Ellis Vickie Ellis Raphael Pollock Kristine R. Broglio Kenneth Hess Steven A. Curley | | Annals of Surgery0，，： | 1 |
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