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| 1 | Pakl mediates the stimulatory effect of insulin and curcumin on hepatic ChREBP expression显示文摘 | Kejing Zeng Lili Tian Adam Sirek Weijuan Shao Ling Liu Yu-Ting Chiang Jonathan Chernoff Dominic S. Ng Jianping Weng Tianru Jin | 2017 | Journal of Molecular Cell Biology2017,9,5: | 4 |
| 2 | Role of β-microseminoprotein from prostate cancer initiationto recurrence: A mini-review显示文摘Medline/Pubmed articles relevant to this topic were considered using the search terms ?-microseminoprotein, MSMB, prostate secretory protein of 94 amino acids and PSP94. Full articles were retrieved when the abstract was considered relevant. In addition, other data related to this topic including our own are discussed. Summary of fi ndings-?-microseminoprotein(MSMB) is increasingly being considered as a marker for prostatecancer, as reduced levels have been associated with the disease. Here we review various aspects of this protein including its biological and physiological variants, binding proteins and immune modulation; its importance as a marker for biochemical recurrence of prostate cancer; prostate cancer related splice variants and its therapeutic utility. Two of the most important properties of MSMB are related to anticancer functions and immune modulation. Predominant expression of two(short and full-length) splice variants of MSMB has been observed from normal prostate and several other tissues. In benign prostate hyperplasia the short isoform is dominant, constituting 98% of this isoform, whereas in prostate cancer 96% constitute the fulllength isoform. The MSMB promoter single nucleotide polymorphism rs10993994 with the C allele functions as an activated cyclic adenosine monophosphate response element binding protein binding site. This C variant of rs10993994 could be responsible for the production of splice variants under variable conditions. MSMB has binding motifs to a few known proteins including immunoglobulin G and several Cysteine-rich secretory proteins family proteins. MSMB bound to these proteins is considered as immune modulating. Use of MSMB as a urinary marker for detecting aggressive prostate cancers that could resist radiation and surgical treatments, seems possible, but needs further investigation. The ratio of MSMB splice variants could also be a possible approach in understanding prostate cancers, with higher ratios indicating severe disease. | Nishi Karunasinghe Karen Bishop Pamela Murray Yuanye Xu Megan Goudie Lance Ng Shuotun Zhu Dug Yeo Han Lynnette R Ferguson Jonathan Masters Benji Benjamin Michael Holmes | 2014 | World Journal of Clinical Urology2014,3,1: | 2 |
| 3 | Side Resistance of Large Diameter Bored Piles Socketed into Decomposed Rocks显示文摘 | Charles W. W. Ng Terence L. Y. Yau Jonathan H. M. Li Wilson H. Tang | 2001 | Journal of Geotechnical and Geoenvironmental Engineering2001,,8: | 2 |
| 4 | Vascular tumors in livers with targeted inactivation of the von Hippel-Lindau tumor suppresser显示文摘 | Volker HH Jonathan NG Merav S | 2001 | PANS2001,98,4: | 1 |
| 5 | Dispatching vehicles in a mega container terminal显示文摘 | Ebru K. Bish Frank Y. Chen Yin Thin Leong Barry L. Nelson Jonathan Wing Cheong Ng David Simchi-Levi | 2005 | OR Spectrum2005,,4: | 1 |
| 6 | The evolution of allograft bone for spinal applications显示文摘 | Jonathan NG John MBBrian K | | 0,,06: | 1 |
| 7 | Lecithin:Cholesterol Acyltransferase Deficiency Protects against Cholesterol-induced Hepatic Endoplasmic Reticulum Stress in Mice显示文摘 | Lauren Hager Lixin Li Henry Pun Lu Liu Mohammad A. Hossain Graham F. Maguire Mark Naples Chris Baker Lilia Magomedova Jonathan Tam Khosrow Adeli Carolyn L. Cummins Philip W. Connelly Dominic S. Ng | 2012 | Journal of Biological Chemistry2012,,24: | 1 |
| 8 | Preliminary results of radiation dose escalation for locally advanced nasopharyngeal carcinoma显示文摘 | Dora L.W. Kwong Jonathan S.T. Sham Lucullus H.T. Leung Ashley C.K. Cheng W.M. Ng Philip W.K. Kwong W.M. Lui C.C. Yau P.M. Wu William Wei Gordon Au | 2006 | International Journal of Radiation Oncology Biology Physics2006,,2: | 1 |
| 9 | Side Resistance of Large Diameter Bored Piles Socketed into Decomposed Rocks显示文摘 | Charles W. W. Ng Terence L. Y. Yau Jonathan H. M. Li Wilson H. Tang | 2001 | Journal of Geotechnical and Geoenvironmental Engineering2001,,8: | 1 |
| 10 | Incremental Prognostic Value of Novel Left Ventricular Diastolic Indexes for Prediction of Clinical Outcome in Patients With ST-Elevation Myocardial Infarction显示文摘 | Miriam Shanks Arnold C.T. Ng Nico R.L. van de Veire M. Louisa Antoni Matteo Bertini Victoria Delgado Gaetano Nucifora Eduard R. Holman Jonathan B. Choy Dominic Y. Leung Martin J. Schalij Jeroen J. Bax | 2010 | The American Journal of Cardiology2010,,: | 1 |
| 11 | Surgical Resection of Gastrointestinal Stromal Tumors After Treatment with Imatinib显示文摘 | Robert H. I. Andtbacka MD CM Chaan S. Ng MD Courtney L. Scaife MD Janice N. Cormier MD MPH Kelly K. Hunt MD Peter W. T. Pisters MD Raphael E. Pollock MD PhD Robert S. Benjamin MD Michael A. Burgess MD Lei L. Chen MD PhD Jonathan Trent MD Shreyaskumar | 2007 | Annals of Surgical Oncology2007,,1: | 1 |
| 12 | Surgical Resection of Gastrointestinal Stromal Tumors After Treatment with Imatinib显示文摘 | Robert H. I. Andtbacka MD CM Chaan S. Ng MD Courtney L. Scaife MD Janice N. Cormier MD MPH Kelly K. Hunt MD Peter W. T. Pisters MD Raphael E. Pollock MD PhD Robert S. Benjamin MD Michael A. Burgess MD Lei L. Chen MD PhD Jonathan Trent MD Shreyaskumar | 2007 | Annals of Surgical Oncology2007,,1: | 1 |
| 13 | Pancreatic Serous Cystadenocarcinoma: A Case Report and Review of the Literature显示文摘 | Jonathan C. King Tina T. Ng Stephen C. White Galen Cortina Howard A. Reber O. Joe Hines | 2009 | Journal of Gastrointestinal Surgery2009,,10: | 1 |
| 14 | Utilising inkjet printed paraffin wax for cell patterning applications显示文摘We describe a method to prepare patterned environments for eukaryotic cells by inkjet printing paraffin wax onto a substrate.This technique bypasses the requirement to create a master mould,typically required with the use of polydimethylsiloxane techniques and the printed structure could be immediately used to guide cell proliferation.In a space of 2–3 hours,the desired pattern could be created with computer assisted design,printed and have cells seeded onto the scaffold,which could reduce the cycle time of prototyping micropattern designs.Human dermal fibroblasts and RN22 Schwann cells were seen to proliferate within the fabricated patterns and survive for more than 7 days.Additionally,the wax constructs could be readily removed from the substrate at any stage after cell seeding with the cells continuing to proliferate.Thus,we report on a simple but novel approach for the controlled physical positioning of live cells by wax inkjet printing. | Christopher Chi Wai Tse Shea Shin Ng Jonathan Stringer Sheila MacNeil John W.Haycock Patrick J.Smith | 2016 | International Journal of Bioprinting2016,2,1: | 0 |
| 15 | Liver decompensation after rapid weight loss from semaglutide in a patient with non-alcoholic steatohepatitis -associated cirrhosis显示文摘There is rapidly increasing uptake of GLP-1 (glucagon-like peptide-1) agonistssuch as semaglutide worldwide for weight loss and management of non-alcoholicsteatohepatitis (NASH). remains a paucity of safety data in the vulnerable NASHcirrhotic population. We report herein the first documented case of liver decompensationand need for liver transplant waitlisting in a patient with NASHcirrhosistreated with semaglutide. Rapid weight loss led to the development ofascites and hepatic encephalopathy and an increase in the patients Model forEndstage Liver Disease-Na (MELD-Na) score from 11 to 22. Aggressive nutritionalsupplementation was commenced and the semaglutide was stopped. Overthe following months she regained her weight and her liver recompensated andher MELD-Na decreased to 13, allowing her to be delisted from the transplantwaitlist. This case serves as a cautionary tale to clinicians using semaglutide in thecirrhotic population and highlights the need for more safety data in this patientgroup. | Matthew Peverelle Jonathan Ng James Peverelle Ryan D.Hirsch Adam Testro | 2023 | World Journal of Gastroenterology2023,29,47: | 0 |
| 16 | Nasopharyngeal carcinoma research in Hong Kong in the past decade显示文摘NasopharyngealcarcinomaresearchinHongKonginthepastdecadeJonathanS.T.Sham,WiliamWei,M.H.Ng,J.NicholsandDamonChoyDepartmentsofR... | Jonathan S.T. Sham, William Wei, M.H. Ng, J. Nicholls and Damon Choy | 1997 | Chinese Medical Journal1997,,11: | 0 |