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| 1 | Role of radiation therapy in gastric adenocarcinoma显示文摘在有在美国的胃的癌症的病人的结果仍然保持令人失望,与约 23% 的五年的全面幸存率。本地人地区性的控制追随者外科的给定的高率,一个强壮的基本原理为辅助放射治疗的使用存在。使随机化的审判与辅助放射疗法显示出优异本地控制并且与辅助 chemoradiation 改进全面幸存。在由一位富有经验的外科医生经历了 D2 淋巴节点解剖的病人的辅助 chemoradiation 的利益不被知道,并且除了辅助化疗的辅助放射治疗的利益继续定义。在 unresectable 疾病, chemoradiation 在病人的一个小数字允许长期的幸存并且提供有效减轻。大多数试用独自与化疗或放射治疗相比显示出一个好处到联合形式治疗。使用外科手术前, intra 起作用, 3D 保角,并且在胃的癌症的调制放射治疗进一步正在答应,但是要求的紧张学习。当前的文章在能的将切除的治疗考察放射治疗的角色,集中于在美国的当前的建议并且 unresectable 胃的癌。 | Lisa Hazard John O'Connor Courtney Scaife | 2006 | World Journal of Gastroenterology2006，12，10： | 15 |
| 2 | Therapeutic regulation of autophagy in hepatic metabolism显示文摘Metabolic homeostasis requires dynamic catabolic and anabolic processes. Autophagy, an intracellular lysosomal degradative pathway, can rewire cellular metabolism linking catabolic to anabolic processes and thus sustain homeostasis. This is especially relevant in the liver, a key metabolic organ thatgoverns body energy metabolism. Autophagy’s role in hepatic energy regulation has just begun to emerge and autophagy seems to have a much broader impact than what has been appreciated in the field. Though classically known for selective or bulk degradation of cellular components or energy-dense macromolecules, emerging evidence indicates autophagy selectively regulates various signaling proteins to directly impact the expression levels of metabolic enzymes or their upstream regulators. Hence, we review three specific mechanisms by which autophagy can regulate metabolism: A) nutrient regeneration, B) quality control of organelles, and C) signaling protein regulation. The plasticity of the autophagic function is unraveling a new therapeutic approach. Thus, we will also discuss the potential translation of promising preclinical data on autophagy modulation into therapeutic strategies that can be used in the clinic to treat common metabolic disorders. | Katherine Byrnes Sophia Blessinger Niani Tiaye Bailey Russell Scaife Gang Liu Bilon Khambu | 2022 | Acta Pharmaceutica Sinica B2022，12，1： | 11 |
| 3 | Seasonal Forecasts of the Summer 2016 Yangtze River Basin Rainfall显示文摘The Yangtze River has been subject to heavy flooding throughout history,and in recent times severe floods such as those in 1998 have resulted in heavy loss of life and livelihoods.Dams along the river help to manage flood waters,and are important sources of electricity for the region.Being able to forecast high-impact events at long lead times therefore has enormous potential benefit.Recent improvements in seasonal forecasting mean that dynamical climate models can start to be used directly for operational services.The teleconnection from El Ni ?no to Yangtze River basin rainfall meant that the strong El Ni ?no in winter 2015/16 provided a valuable opportunity to test the application of a dynamical forecast system.This paper therefore presents a case study of a real-time seasonal forecast for the Yangtze River basin,building on previous work demonstrating the retrospective skill of such a forecast.A simple forecasting methodology is presented,in which the forecast probabilities are derived from the historical relationship between hindcast and observations.Its performance for2016 is discussed.The heavy rainfall in the May–June–July period was correctly forecast well in advance.August saw anomalously low rainfall,and the forecasts for the June–July–August period correctly showed closer to average levels.The forecasts contributed to the confidence of decision-makers across the Yangtze River basin.Trials of climate services such as this help to promote appropriate use of seasonal forecasts,and highlight areas for future improvements. | Philip E. BETT Adam A. SCAIFE Chaofan LI Chris HEWITT Nicola GOLDING Peiqun ZHANG Nick DUNSTONE Doug M. SMITH Hazel E. THORNTON Riyu LU Hong-Li REN | 2018 | Advances in Atmospheric Sciences2018，35，8： | 3 |
| 4 | Sequence analysis of ARI-1,a novel OXA beta-lactamase,responsible for imipenem resistance in Acinetobacter baumannii 6B92显示文摘 | Donald HM Scaife W Amyes SG | 2000 | Antimicrob Agents Chemother2000，，： | 1 |
| 5 | Characterization of cyanobacterial 显示文摘 | Scaife M A Burja A M Wright P C | 2009 | Biotechnol Bioeng2009，103，5： | 1 |
| 6 | Sequence analysis of ARI-1, a novel OXA beta-lactamase, responsible for imipenem resistance in Acinetobacter baumannii 6B92显示文摘 | Donald HM Scaife W Amyes SG | 2000 | Antimicrob Agents Chemother2000，44，： | 1 |
| 7 | Sequence analysis of ARI-l,a novel OX A beta-lactamase, responsible for imipenem resist-ance in Acinetobacter baumannii 6B92 显示文摘 | Donald HM Scaife W Amyes SG | 2000 | Antimicrob AgentsChemother2000，44，1： | 1 |
| 8 | Intraoperative radiotherapy in the multimodality approach to gastric cancer显示文摘 | Scaife CL Calvo FA Noyes RD | 2003 | Surg Oncol Clin North Am2003，12，： | 1 |
| 9 | Sequence analysis of ARI,a noval OXA laetamase,responsible for inipenim resistance in Acinetobacter baumannii 6 B92显示文摘 | SCAIFE W AMYES S G | 2004 | Antimierob Agents Chemother2004，44，： | 1 |
| 10 | Sequence analysis of ARI-1,a novel OXA β-lactamase,responsible for imipenem resistancein Acinetobacter baumannii 6B92显示文摘 | Donald HM Scaife W Amyes SG | 2000 | Antimicrob Agents Chemother2000，44，1： | 1 |
| 11 | Comparisons of the effect of genotype and protected methionine supplementation on growth, digestive characteristics and fibre yield in cashmere- yielding and Angora goats显示文摘 | Souri M Galbraith H Scaife J R | 1998 | Journal of Animal Science1998，66，： | 1 |
| 12 | Study of dissected lamb muscles by visible and near infrared reflectance spectroscopy for composition assessment 显示文摘 | Cozzolino D Murray I Scaife J R | 2000 | Animal Science2000，70，3： | 1 |
| 13 | Development of c-ompetent children's ward co-ordinators 显示文摘 | SCAIFE C OCTOBER M KELLEIT V | 2014 | Nurs ChildYoung People2014，26，6： | 1 |
| 14 | Sequence Analysis of ARId, a Novel OXA β-Lactamase, Responsible for Imipenem Resistance in Acinetobacter baumannii 6B92显示文摘 | Donald HM Scaife W Amyes SGB | 2000 | Antilnicrob Agents Chemother2000，44，1： | 1 |
| 15 | Sequence analysis of ARI-, a noval OXA-lactamase, responsible for inipenim resistance in Acinetobacter baumannii 6 B92 显示文摘 | DONALD H M SCAIFE W AMYES S G | 2000 | Antimicrob Agents Chemother2000，44，6： | 1 |
| 16 | 显示文摘 | Scaife D E | 1980 | Solar Engergy1980，25，： | 1 |
| 17 | Sequence analysis of ARI-1, a novel OXA beta-lactamase, responsible for imipenem resistance in Acinetobacter baumannii 显示文摘 | Donald H M Scaife W Amyes S G | 2000 | Antimierob Agents Chemother2000，44，1： | 1 |
| 18 | Unravelling vitamin B12-responsive gene regulation in algae显示文摘 | Helliwell KE Scaife MA Sasso S | 2014 | Plant Physiology2014，165，1： | 1 |
| 19 | Oxide semiconductors in photoelectrochemical conversion of solar energy显示文摘 | Scaife D E | 1980 | Solar Energy1980，25，1： | 1 |
| 20 | Effect of different dietary supplemental fats and oils on the tissue fatty acid composition and growth of female broilers显示文摘 | SCAIFE J R MOYO J GALBRAITH H | 1994 | British Poultry Science1994，35，1： | 1 |
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