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| 1 | Radiofrequency ablation for early oesophageal squamous neoplasia:Outcomes form United Kingdom registry显示文摘AIM:To report outcomes on patients undergoing radiofrequency ablation(RFA)for early oesophageal squamous neoplasia from a National Registry.METHODS:A Prospective cohort study from 8 tertiary referral centres in the United Kingdom.Patients with squamous high grade dysplasia(HGD)and early squamous cell carcinoma(ESCC)confined to the mucosa were treated.Visible lesions were removed by endoscopic mucosal resection(EMR)before RFA.Following initial RFA treatment,patients were followed up 3monthly.Residual flat dysplasia was treated with RFA until complete reversal dysplasia(CR-D)was achieved or progression to invasive Squamous cell cancer defined as infiltration into the submucosa layer or beyond.The main outcome measures were CR-D at 12 mo from start of treatment,long term durability,progression to cancer and adverse events.RESULTS:Twenty patients with squamous HGD/ESCC completed treatment protocol.Five patients(25%)had EMR before starting RFA treatment.CR-D was 50%at12 mo with a median of 1 RFA treatment,mean 1.5(range 1-3).Two further patients achieved CR-D with repeat RFA after this time.Eighty per cent with CR-D remain dysplasia free at latest biopsy,with median follow up 24 mo(IQR 17-54).Six of 20 patients(30%)progressed to invasive cancer at 1 year.Four patients(20%)required endoscopic dilatations for symptomatic structuring after treatment.Two of these patients have required serial dilatations thereafter for symptomatic dysphagia with a median of 4 dilatations per patient.The other 2 patients required only a single dilatation to achieve an adequate symptomatic response.One patient developed cancer during follow up after end of treatment protocol.CONCLUSION:The role of RFA in these patients re-mains unclear.In our series 50%patients responded at12 mo.These figures are lower than limited published data. | Rehan J Haidry Mohammed A Butt Jason Dunn Matthew Banks Abhinav Gupta Howard Smart Pradeep Bhandari Lesley Ann Smith Robert Willert Grant Fullarton Morris John Massimo Di Pietro Ian Penman Marco Novelli Laurence B Lovat | 2013 | World Journal of Gastroenterology2013，19，36： | 7 |
| 2 | Gliotoxin Stimulates the Apoptosis of Human and Rat Hepatic Stellate Cells and Enhances the Resolution of Liver Fibrosis in Rats显示文摘 | Matthew C. Wright Razo Issa David E. Smart Nathan Trim Graeme I. Murray John N. Primrose Michael J.P. Arthur John P. Iredale Derek A. Mann | 2001 | Gastroenterology2001，，3： | 2 |
| 3 | 清管和化学处理在管线维护中的应用显示文摘化学处理和利用清管器的机械清理是两种最常见的管线内部维护方法 ,为了对管线发生的问题进行高效低耗的控制 ,在实际应用中常把二者结合起来。本文对管线运行过程中内部可能发生的各种问题进行了分析 ,并提出了可行的处理方法。最后 。 | 刘丹 姚煦春 Gary Smith John Smart | 2001 | 国外油田工程2001，17，4： | 2 |
| 4 | Method for calculating corrosion allowance for deepwater pipelines and risers显示文摘 | Dr John Smart | 2001 | Corrosion Prevention & Control2001，，6： | 1 |
| 5 | Maintaining Effectiveness Amid Downsizing and Decline in Institutions of Higher Education显示文摘 | Cameron Kim and Smart John | 1998 | Research in Higher Education1998，，： | 1 |
| 6 | Maintaining Effective- ness Amid Downsizing and Decline in Institution of Higher Education 显示文摘 | Cameron Kim Smart John | 1998 | Research in Higher Education1998，，1： | 1 |
| 7 | Battery electric vehicle driving and charging behavior observed early in the EV project显示文摘 | John Smart Stephen Schey | 2012 | SAE International Journal of Alternative Powertrains2012，1，1： | 1 |
| 8 | The production and characterization of novel conducting redox-active oligomeric thin films from electrooxidised indolocarbazole显示文摘 | Wharton Smart I Henry John B MaNab Hamish | 2009 | Chemistry-A European Journal2009，15，22： | 1 |
| 9 | Integration of visual and olfactory cues of hosts and non-hosts by three bark beetles ( Coleeptera: Sco- lytidae) 显示文摘 | Smart A Campbell John H Borden | 2006 | Ecological Entomology2006，31，： | 1 |
| 10 | In Vitro Adherence Properties of Lac- tobacillus Rhamnosus DR20 and Bifidobaeterium Lac- tis DR10 Strains and Their Antagonistic Activity A- gainst an Enterotoxigenic Escherichia Coli显示文摘 | PRAMOD K GOPAL JAYA PRASAD JOHN SMART | 2001 | Interna- tional Journal of Food Microbiology2001，67，3： | 1 |
| 11 | An atomic force microscopy investigation of bioadhesive polymer adsorption onto human buccal cells显示文摘 | Dharmendra Patel James R Smith Andrew W Smith Nigel Grist Paul Barnett John D Smart | 2000 | International Journal of Pharmaceutics2000，，2： | 1 |
| 12 | On the (MILD) combustion of gaseous, liquid, and solid fuels in high temperature preheated air显示文摘 | Roman Weber John P. Smart Willem vd Kamp | 2004 | Proceedings of the Combustion Institute2004，，2： | 1 |
| 13 | The effect of extreme temperature in an oxidising atmosphere on dense tantalum carbide (TaC)显示文摘 | Anna Lashtabeg Michael Smart Daniel Riley Andrew Gillen John Drennan | 2013 | Journal of Materials Science2013，，1： | 1 |
| 14 | Molecular Analysis to Detect Pancreatic Ductal Adenocarcinoma in High-Risk Groups显示文摘 | Li Yan Christopher McFaul Nathan Howes Jane Leslie Gillian Lancaster Theresa Wong Jane Threadgold Jonathan Evans Ian Gilmore Howard Smart Martin Lombard John Neoptolemos William Greenhalf | 2005 | Gastroenterology2005，，7： | 1 |
| 15 | Perceived quality and citation rates of education journals显示文摘 | Smart John C | | 0，，02： | 1 |
| 16 | Selection and characterisation of Lactobacillus and Bifidobacterium strains for use as probiotics显示文摘 | Jaya Prasad Harsharanjit Gill John Smart | 1998 | Dairy Journal1998，8，12： | 1 |
| 17 | Radiofrequency Ablation and Endoscopic Mucosal Resection for Dysplastic Barrett’s Esophagus and Early Esophageal Adenocarcinoma: Outcomes of the UK National Halo RFA Registry显示文摘 | Rehan J. Haidry Jason M. Dunn Mohammed A. Butt Matthew G. Burnell Abhinav Gupta Sarah Green Haroon Miah Howard L. Smart Pradeep Bhandari Lesley Ann Smith Robert Willert Grant Fullarton John Morris Massimo Di Pietro Charles Gordon Ian Penman Hugh Barr Praf | 2013 | Gastroenterology2013，，1： | 1 |
| 18 | Differences in recommendations between the Allergic Rhinitis and its Impact on Asthma Update 2010 and US Rhinitis Practice Parameters显示文摘 | Bradley Chipps Sheldon Spector Judith Farrar Warner Carr Eli Meltzer William Storms Michael Kaliner Allan Luskin Donald Bukstein John Oppenheimer Brian Smart Jenifer Derebery Julia Harder Mark Dykewicz Michael Benninger | 2011 | The Journal of Allergy and Clinical Immunology2011，，6： | 1 |
| 19 | On the (MILD)combustion of gaseous,liquid, and solid fuels in high temperaturepreheated air显示文摘 | Roman Weber John P Smart Willem vd Kamp | 2005 | Proceedings of the Combustion Institute2005，30，2： | 1 |
| 20 | Biodiesel from algae: Challenges and prospects显示文摘 | Scott Smart A Davey Matthew P Dennis John S | 2010 | Current Opinion in Biotechnology2010，21，： | 1 |
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